Choline: what it does, by goal, and the dose that worked

What the 157 human studies of choline we graded show for each goal, the dose that worked, and the products that hold it. This page is educational, not medical advice.

Human studies graded
157
Goals with an improvement
5
Products
8
Ranked
8
Biohacker opinions
9/10
What it does, by goalMembersThe top 5 of 12 goals

8 of these 157 human studies gave choline by drip or injection, not by mouth.

GoalWhat the studies showStudiesDose that worked
Improved in studies 59 studies, 23 showed an improvement, 6 found none, 9 pooled analyses, 2 by drip, injection or inhaler59500 mg
Improved in studies 28 studies, 15 showed an improvement, 1 found none, 2 pooled analyses, 4 by drip, injection or inhaler28250 mg
Improved in studies 18 studies, 5 showed an improvement, 3 found none, 1 pooled analysis, 1 by drip, injection or inhaler18480 mg
Improved in studies 2 studies, 1 showed an improvement2–
Improved in studies 1 study, it showed an improvement110 mg
Too few studies 6 studies, 1 found none, 2 pooled analyses6–
Too few studies 3 studies, no clear result yet3–
Too few studies 2 studies, no clear result yet2–
Too few studies 1 study, no clear result1–
No effect in studies 20 studies, 4 showed an improvement, 4 found none, 1 pooled analysis20–
No effect in studies 20 studies, 4 showed an improvement, 3 found none, 4 pooled analyses, 1 by drip, injection or inhaler20500 mg
No effect in studies 8 studies, 1 showed an improvement, 2 found none8–

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Products – highest ranked firstMembersThe top 3 of 8
Dose and safetyThe dose that worked and the upper limit

The studies taken by mouth that showed an improvement gave 10 mg to 25 g a day.

Biohacker panelMembersWhat our 10 biohackers say about choline
Questions people askMembersAnswered from the figures on this page

What is choline good for?

Answer for members.

How much choline a day?

Answer for members.

Can I take choline with my meds?

Answer for members.

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Educational, not medical advice. Figures come from the human studies on PubMed we have graded; a study counts for a form when it names the form it used. Updated as new studies arrive. How we grade →