Citrulline: what it does, by goal, and the dose that worked

What the 61 human studies of citrulline we graded show for each goal, the dose that worked, and the products that hold it. This page is educational, not medical advice.

Human studies graded
61
Goals with an improvement
2
Products
3
Ranked
3
Biohacker opinions
9/10
What it does, by goalMembersThe top 3 of 3 goals

1 of these 61 human studies gave citrulline by drip, not by mouth.

GoalWhat the studies showStudiesDose that worked
Improved in studies 30 studies, 15 showed an improvement, 7 found none, 3 pooled analyses, 1 by drip, injection or inhaler302 g
Improved in studies 8 studies, 5 showed an improvement8800 mg
No effect in studies 27 studies, 8 showed an improvement, 11 found none, 7 pooled analyses276 g

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Products – highest ranked firstMembersThe top 3 of 3
Dose and safetyThe dose that worked and the upper limit

The studies taken by mouth that showed an improvement gave 800 mg to 10 g a day.

Biohacker panelMembersWhat our 10 biohackers say about citrulline
Questions people askMembersAnswered from the figures on this page

What is citrulline good for?

Answer for members.

How much citrulline a day?

Answer for members.

Can I take citrulline with my meds?

Answer for members.

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Educational, not medical advice. Figures come from the human studies on PubMed we have graded; a study counts for a form when it names the form it used. Updated as new studies arrive. How we grade →