Niacin: what it does, by goal, and the dose that worked

What the 309 human studies of niacin we graded show for each goal, the dose that worked, and the products that hold it. This page is educational, not medical advice.

Human studies graded
309
Goals with an improvement
10
Products
16
Ranked
15
Biohacker opinions
10/10
What it does, by goalMembersThe top 5 of 21 goals

3 of these 309 human studies gave niacin by drip, injection or inhaler, not by mouth.

GoalWhat the studies showStudiesDose that worked
Improved in studies 34 studies, 9 showed an improvement, 11 found none, 1 pooled analysis, 2 by drip, injection or inhaler34200 mg
Improved in studies 21 studies, 8 showed an improvement, 3 found none, 1 pooled analysis2150 mg
Improved in studies 16 studies, 4 showed an improvement, 3 pooled analyses161 g
Improved in studies 9 studies, 3 showed an improvement, 1 by drip, injection or inhaler9–
Improved in studies 7 studies, 2 showed an improvement74 %
Improved in studies 6 studies, 2 showed an improvement, 3 found none6–
Improved in studies 2 studies, both showed an improvement2–
Improved in studies 10 studies, 1 showed an improvement, 3 found none, 1 pooled analysis10–
Improved in studies 3 studies, 1 showed an improvement, 1 found none3–
Improved in studies 2 studies, 1 showed an improvement2–
Too few studies 4 studies, 1 found none4–
Too few studies 3 studies, no clear result yet3–
Too few studies 2 studies, no clear result yet2–
No effect in studies 51 studies, 20 showed an improvement, 7 found none, 6 pooled analyses51200 mg
No effect in studies 45 studies, 20 showed an improvement, 4 found none, 10 pooled analyses451.5 g
No effect in studies 57 studies, 11 showed an improvement, 23 found none, 8 pooled analyses574 mg
No effect in studies 30 studies, 9 showed an improvement, 9 found none, 7 pooled analyses30500 mg
No effect in studies 31 studies, 5 showed an improvement, 12 found none, 4 pooled analyses31500 mg
No effect in studies 16 studies, 4 showed an improvement, 8 found none161.9 mg
No effect in studies 8 studies, 1 showed an improvement, 2 found none865 mg
No effect in studies 2 studies, both found no effect2–

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Products – highest ranked firstMembersThe top 3 of 16
Dose and safetyThe dose that worked and the upper limit

The studies taken by mouth that showed an improvement gave 1.9 mg to 4 g a day.

Biohacker panelMembersWhat our 10 biohackers say about niacin
Questions people askMembersAnswered from the figures on this page

What is niacin good for?

Answer for members.

How much niacin a day?

Answer for members.

Can I take niacin with my meds?

Answer for members.

Members see the answers, checked against their own meds and goals. Start My 7-Day Free Trial →

Educational, not medical advice. Figures come from the human studies on PubMed we have graded; a study counts for a form when it names the form it used. Updated as new studies arrive. How we grade →