Methylcobalamin: what the studies show, and the products
33 of the human studies we graded used methylcobalamin, and 9 showed an improvement. Its products are graded on the studies of every form of vitamin B12. This page is educational, not medical advice.
What it does, by goalMembersThe top 5 of 12 goals
2 of these 27 human studies gave methylcobalamin by injection, not by mouth.
| Goal | What the studies show | Studies | Dose that worked |
|---|---|---|---|
| Improved in studies 7 studies, 2 showed an improvement, 2 found none, 1 pooled analysis | 7 | – | |
| Improved in studies 3 studies, 2 showed an improvement | 3 | – | |
| Improved in studies 2 studies, both showed an improvement | 2 | 500 mcg | |
| Improved in studies 5 studies, 1 showed an improvement, 2 found none, 1 by drip, injection or inhaler | 5 | – | |
| Improved in studies 4 studies, 1 showed an improvement, 1 found none, 1 by drip, injection or inhaler | 4 | 1 mg | |
| Improved in studies 2 studies, 1 showed an improvement | 2 | 1.5 mg | |
| Too few studies 3 studies, no clear result yet, 1 pooled analysis | 3 | – | |
| Too few studies 2 studies, no clear result yet | 2 | – | |
| Too few studies 1 study, no clear result | 1 | – | |
| Too few studies 1 study, no clear result | 1 | – | |
| Too few studies 1 study, no clear result | 1 | – | |
| Too few studies 1 study, no clear result | 1 | – |
Members see which goal each result is for, and the products for it. Start My 7-Day Free Trial →
Products – highest ranked firstMembersThe top 3 of 10
Dose and safetyThe dose that worked and the upper limit
The studies of methylcobalamin taken by mouth that showed an improvement gave 500 mcg to 1.5 mg a day.
Biohacker panelMembersWhat our 10 biohackers say about methylcobalamin
Questions people askMembersAnswered from the figures on this page
What is methylcobalamin good for?
Answer for members.
How much methylcobalamin a day?
Answer for members.
Can I take methylcobalamin with my meds?
Answer for members.
Members see the answers, checked against their own meds and goals. Start My 7-Day Free Trial →
Educational, not medical advice. Figures come from the human studies on PubMed we have graded; a study counts for a form when it names the form it used. Updated as new studies arrive. How we grade →