Stress and Calm: supplements ranked by the human studies
We graded 11 stress products in our catalog against the human studies of their ingredients, the dose that worked and what the reviews say, then we rank them based on the evidence. This page is educational, not medical advice.
What the studies sayMembersThe ingredients that work, strongest evidence first
shows a clear improvement in meta-analyses, the largest of people, from a day. shows a clear improvement in meta-analyses, the largest of people, from a day. shows a clear improvement in meta-analysis of 2,471 people. shows a clear improvement in meta-analysis of 2,256 people, from a day. shows a clear improvement in controlled trials, the largest of people, from a day. shows a clear improvement in controlled trials, the largest of people, from a day.
Ingredients with evidenceMembersThe 9 strongest of 16
| Ingredient | Studies read | What they show | Dose that worked |
|---|---|---|---|
| Ashwagandha | 48 | ||
| Folate | 19 | ||
| Cayenne | 6 | – | |
| Thiamin | 4 | ||
| Black Pepper | 6 | ||
| Ginseng | 21 | ||
| Fenugreek | 6 | ||
| Vitamin B6 | 19 | ||
| Riboflavin | 5 | – |
Products – highest ranked firstMembersThe top 3 of 11 ranked, by the studies, then reviews
Biohacker panelMembersHow many of our 10 biohackers recommend each ingredient
Questions people askMembers
What is the best supplement for stress?
Answer for members.
How much ashwagandha a day?
Answer for members.
Can I take these with my meds?
Answer for members.
Members see the answers, checked against their own meds and goals. Start My 7-Day Free Trial →
Educational, not medical advice. Grades come from human studies on PubMed, the dose that worked, store reviews we read ourselves and our biohacker panel. Updated as new studies arrive. How we grade →