Doctor's Best Fisetin with Novusetin Review

At Doctor's Best, antioxidants are at the core of our wellness philosophy. Our formula features Fisetin, a flavonoid known for supporting cellular health and potentially boosting cognitive function, contributing to overall well-being. The product is positioned as science-based nutrition with antioxidant and cognitive support, and is labeled non-GMO, gluten free, soy free and vegan. Key claims on the page state that it helps maintain glutathione levels and mitochondrial function in the presence of oxidative stress, that it may help maintain neuronal function, and that it provides flavonol antioxidant support for healthy aging. The Supplement Facts panel lists a serving size of 1 veggie capsule with 30 servings per container, and each serving provides 100 mg of Fisetin (as Novusetin) from Rhus succedanea stem, with no established Daily Value. Suggested adult use is to take 1 capsule daily with food, or as recommended by a nutritionally informed physician. The page advises storing the product in a cool dry place. Novusetin is noted as a registered trademark of Omega Protein Corporation, d/b/a Nutegrity. The page also notes that the product contains natural ingredients that may vary in color. A fisetin fact sheet is linked from the description. A disclaimer states that these statements have not been evaluated by the FDA and that the product is not intended to diagnose, treat, cure, or prevent any disease. The page also carries a general notice that packaging and ingredients may change pending site updates, and that items may occasionally ship with alternate packaging while freshness is always guaranteed. Readers are advised to read labels, warnings and directions before use. The product is currently shown as sold out on this page, and the one-time purchase price is $22.99 with an autoship option at $21.84. No written customer reviews or rating counts appear on the scraped text, so no review statistics can be reported from this page alone. The page does not provide a star histogram, so positive, neutral and negative shares are left empty. The page offers a subscription option managed through Recharge, with a five percent discount for autoship orders, and the product is presented as a single veggie capsule dosage form.

Product Focus: Healthy AgingAlso covers:BrainHeart
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$23

Study, Trial or Testing Result Summary

MembersHuman studies

Fisetin is the only active ingredient, at 100 milligrams a day. the evidence for reversing aging comes from animal and lab studies; study measured this in people, and human dose has been shown to , so it is unclear whether this dose matters. …

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Review Totals and Summary

Members4,146 reviews
4,146 reviews · IHerb 3,055 · EBay 861 · Vitacost 213 · Naturitas 9 · Walmart 5 · Swanson Vitamins 3

Doctor's Fisetin with Novusetin capsules have accumulated approximately 3276 ratings across various retail platforms, with a of of starred reviews giving 4 or 5 stars. Overall, customers express general with the product, though some remain uncertain about its . …

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Biohacker Summary

MembersWhat our biohacker panel says

Three lean toward using or it, mainly as a senolytic that old, worn-out cells, with one adding that it comes from strawberries and another listing it as a plant compound that supports a cell defense pathway. Doses mentioned include 500 milligrams during a water fast alongside quercetin, 500 to 1000 milligrams, a 4 or 5 day course, and 100 milligrams once a month for 3 days. …

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RAL Summary

MembersThe tier and why

More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Cellular aging, Nervous system, Kidneys, Metabolism, Cardiovascular system. Combine with and possible side are for members.

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Supplement Facts

Fisetin 100 mg
Supplement Facts
Serving Size 1 Veggie Capsule
Servings Per Container 30
Amount Per Serving% Daily Value
Fisetin (as Novusetin®) (from Rhus succedanea) (stem)100 mg†
† Daily Value not established.

Other ingredients: Microcrystalline cellulose, hypromellose (vegetarian capsule), magnesium stearate (vegetable source).

Directions: Suggested Adult Use: Take 1 capsule daily with food, or as recommended by a nutritionally informed physician.

Label source: Doctorsbest · Report a label change

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Our articles on this subject

Graded October 26, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.