hims RX skin Review
Hims RX Skin represents a comprehensive line of prescription and over-the-counter skincare solutions primarily designed for men, accessible through a convenient telehealth platform. The core of Hims' prescription skincare offerings revolves around customized formulations targeting common concerns such as anti-aging, acne, and hyperpigmentation. These personalized treatments are not off-the-shelf products; instead, they are formulated after an online consultation with a licensed medical provider who assesses individual skin conditions, health history, and treatment goals. For anti-aging, Hims' prescription creams often feature a blend of clinically proven ingredients like tretinoin, azelaic acid, and niacinamide. Tretinoin, a potent retinoid derived from Vitamin A, is a cornerstone of these formulations. It works by accelerating skin cell turnover, meaning older, damaged skin cells are shed more rapidly, making way for newer, healthier cells. This process helps to visibly reduce the appearance of fine lines, wrinkles, and dark spots, while also stimulating collagen production for improved skin elasticity and firmness. Niacinamide, a form of Vitamin B3, complements tretinoin by offering hydrating properties, reducing redness, and further addressing dark spots and uneven skin tone. Azelaic acid, another active ingredient, contributes to minimizing wrinkles and improving skin elasticity. For acne treatment, Hims offers customized gel creams that may contain a mix of up to five ingredients, including prescription-strength retinoids (like tretinoin) and topical meds such as clindamycin and zinc pyrithione, alongside niacinamide and azelaic acid. Tretinoin aids in shedding old skin cells and preventing clogged pores, while clindamycin and zinc pyrithione work to combat acne-causing bacteria and reduce inflammation. This multi-ingredient approach allows for a targeted attack on various types of acne, including whiteheads, blackheads, and more severe breakouts. Beyond prescription options, Hims also provides non-prescription skincare products like the Goodnight Wrinkle Cream, Vitamin C Serum, and Everyday Moisturizer. The Goodnight Wrinkle Cream, for instance, is designed to be used after prescription treatments and contains ingredients like caffeine and hyaluronic acid to reduce redness, keep skin moisturized, and diminish puffiness. Hyaluronic acid is a powerful humectant that draws moisture into the skin, providing intense hydration, while caffeine helps to de-puff and revitalize the skin. The Vitamin C Serum offers antioxidant benefits to soften skin and reduce wrinkle appearance, and the Everyday Moisturizer focuses on lightweight hydration with ingredients like hyaluronic acid and shea butter. The entire process, from consultation to delivery, is designed for convenience, allowing users to receive tailored treatments directly to their door without traditional in-person doctor visits.
Study, Trial or Testing Result SummaryMembersHuman studies
1 of these 46 human studies gave the ingredient by injection, not by mouth.
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Review Totals and SummaryMembers135 reviews
Biohacker SummaryMembersWhat our biohacker panel says
RAL SummaryMembersThe tier and why
More DetailsMembersBody systems · Combine with · Possible side effects
Supplement FactsTretinoin 0.055 % · Niacinamide 4 % · Azelaic Acid 5 %
| Tretinoin | 0.055 % | † |
| Niacinamide | 4 % | † |
| Azelaic Acid | 5 % | † |
Other ingredients: Water, Cyclopentasiloxane, Polysilicone-11, Laureth-4, Octyldodecanol, Octyldodecyl Xyloside, PEG-30 Dipolyhydroxystearate, Dimethicone, Cyclomethicone, Alcohol, Carapa Guianensis Seed Oil.
Label source: Skinsort · Report a label change
Graded October 24, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
