HPN PA(7) Phosphatidic Acid Review

HPN PA(7) Phosphatidic Acid is a top natural muscle builder designed to significantly enhance muscle mass and strength, offering a 30-day supply in each container. This advanced supplement is backed by rigorous clinical studies, demonstrating remarkable benefits for individuals seeking to optimize their physical performance and body composition. Research has shown that subjects using PA(7) experienced an impressive 200% increase in lean muscle mass, alongside a substantial 47% gain in bench press strength. Beyond muscle development, the supplement also contributes to improved nutrient utilization, with amino acid absorption increasing by as much as 66.7%, and ATP production rising by 18%, which is crucial for cellular energy and performance during workouts. The core mechanism of PA(7) revolves around its ability to increase mTOR activation. mTOR, or mammalian target of a med, is a critical regulator of muscle protein synthesis, a process essential for the growth and repair of skeletal muscle. Scientists have identified that supplying the body with Phosphatidic Acid (PA) can effectively trigger this vital receptor, leading to enhanced muscle building. A key advantage of HPN PA(7) is its safe approach to boosting mTOR activation. Unlike meds, which achieve mTOR activation by elevating testosterone levels and often come with undesirable health complications, PA(7) works at the cellular level within muscle tissues to promote growth without the associated side effects of steroidal compounds. This product is not only scientifically validated but also trusted by professionals. HPN PA(7) is certified Safe for Sport by the NSF, ensuring its purity and absence of banned substances, making it a legal and reliable choice for athletes competing across various professional sports leagues. For optimal results, the directions suggest a flexible dosage regimen: for light to moderate training, individuals can start with 2 tablets per day, taken immediately upon waking or 30 minutes to 1 hour before exercise, with the option to increase to the full dosage of 4 tablets daily if desired. For those engaged in intense training, the recommended dosage is 4 tablets of PA(7) on workout/training days (up to 6 days per week), taken 30 minutes to 1 hour before the session. The product comes in a tablet form, with a unit count of 96, providing 24 total servings per container, and is noted for its natural and Non-GMO material features, suitable for adults.

Product Focus: Muscle and Strength
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$110 at 2 servings
Study, Trial or Testing Result SummaryMembersHuman studies

Phosphatidic acid is present at 1500 milligrams a day, the 750 milligram dose tested. Two trials in men who lifted weights . …

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Review Totals and SummaryMembers2,128 reviews
2,128 reviews · Amazon 1,754 · HPN Supplements 330 · Tiger Fitness 42 · Shop.tiktok 1 · Everybodynutrition 1

Customer feedback for HPN PA7 consistently highlights a sense of efficacy, with users reporting tangible and rapid in their physical performance and muscle development. A prominent theme is the noticeable in energy levels and muscle preservation, enabling individuals to approach their workouts with greater intensity and lift heavier weights. …

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Biohacker SummaryMembersWhat our biohacker panel says

Leucine, the main ingredient, gets a response: six of the nine panelists who spoke on it it, mainly because it is the key signal for building and keeping muscle. Doses came up twice: one gram in a capsule with a normal meal, especially for plant-based eaters, and two to three grams a day for muscle , with about eight or nine grams a day as the optimal range, plus a blend of essential amino acids that is about leucine. …

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RAL SummaryMembersThe tier and why

The rules placed this product in tier two because pooled studies show leucine-rich protein supplements muscle strength and mass, and counted reviews are . The main ingredient, phosphatidic acid, has only two trials that .

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More DetailsMembersBody systems · Combine with · Possible side effects

Body systems: Muscular system. Combine with and possible side are for members.

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Supplement FactsPotassium 0 mg · Total Carbohydrates 0 mg · Mediator ® 1500 mg
Supplement Facts
Serving Size 3 capsules
Servings Per Container 24
Amount Per Serving% Daily Value
Calories00%
Total Fat0 mg0%
Cholesterol0 mg0%
Sodium0 mg0%
Potassium0 mg0%
Total Carbohydrates0 mg0%
Mediator ® (containing Phosphatidic Acid)1,500 mg†
L-Leucine1,400 mg†
AstraGin™Panax Natoginseng and Astragalus Membranaceus (Root)100 mg†
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.

Directions: For Light to Moderate Training; Take 3 capsules per day immediately upon waking or 30 minutes to 1 hour before exercise.

Label source: Tigerfitness · Report a label change

Graded October 23, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.