Life Extension CoQ10 + PQQ Review
The Super Ubiquinol CoQ10 with PQQ from Life Extension is an advanced, bioavailable formula designed to support heart health, combat general fatigue, and enhance cellular energy production. Coenzyme Q10 (CoQ10) is a vital nutrient essential for healthy mitochondrial function, which is the process responsible for generating energy at the cellular level throughout the body. This makes CoQ10 particularly concentrated in high-energy organs such as the brain, liver, kidneys, and especially the heart. Beyond its role in energy, CoQ10 also possesses powerful antioxidant properties, offering protection to cell membranes, lipids, and other crucial cellular components from oxidative stress. A key challenge with standard CoQ10, known as ubiquinone, is its poor absorption by the body. Life Extension addresses this by utilizing ubiquinol, a highly bioavailable form of CoQ10 that maintains healthy blood concentrations more effectively than ubiquinone. Clinical studies have shown that individuals taking ubiquinol can achieve high levels of plasma CoQ10 in as little as four weeks. This improved absorption is crucial for maximizing the benefits of CoQ10, especially as the body's natural CoQ10 levels tend to decline with age, and it is difficult to obtain sufficient amounts through diet alone. This advanced formula is further augmented with two additional powerful ingredients: PQQ (Pyrroloquinoline quinone) and shilajit. PQQ is a potent antioxidant that provides comprehensive cellular and mitochondrial health support, working synergistically with CoQ10 to optimize energy production and cellular protection. Shilajit fulvic acid complex also contributes to the formula's efficacy, enhancing the overall benefits. The combination of ubiquinol CoQ10, PQQ, and shilajit offers triple-action support for cardiovascular health, helps to alleviate the effects of general fatigue, and supports liver health and function. It also works to inhibit inflammatory factors, promoting overall body health. For those seeking to maintain youthful cellular energy and robust heart health, this non-GMO supplement provides a comprehensive and highly absorbable solution. The product is designed for daily use, with one softgel providing 100 mg of Ubiquinol (as Kaneka Ubiquinol™), 100 mg of Shilajit fulvic acid complex, and 10 mg of PQQ disodium salt. This formulation ensures that the body receives the necessary support for vital functions, helping individuals to feel more energetic and focused, as reported by some users.
Study, Trial or Testing Result SummaryMembersHuman studies
Review Totals and SummaryMembers4,714 reviews
Biohacker SummaryMembersWhat our biohacker panel says
RAL SummaryMembersThe tier and why
More DetailsMembersBody systems · Combine with · Possible side effects
Supplement FactsUbiquinol 100 mg · Shilajit fulvic acid complex 100 mg · PQQ disodium salt 10 mg
| Calories | 5 | |
| Total Fat | 0.5 g | |
| Ubiquinol (as Kaneka Ubiquinol™) | 100 mg | † |
| Shilajit fulvic acid complex | 100 mg | † |
| PQQ (Pyrroloquinoline quinone) disodium salt | 10 mg | † |
Other ingredients: Medium chain triglycerides, gelatin, glycerin, purified water, beeswax, sunflower lecithin, annatto color, rosemary extract.
Directions: Take one (1) softgel daily with food, or as recommended by a healthcare practitioner.
Barcode (UPC) 737870173335 · Label source: Lifeextension · Report a label change
Graded October 23, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.

