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Life Extension Glycine and N-Acetyl-L-Cysteine Review

A supplement combining Glycine and N-Acetyl-L-Cysteine (NAC), two amino acids that are precursors to the master antioxidant glutathione. It is designed to support antioxidant defenses and promote cellular health.

Product Focus: Healthy AgingAlso graded for:Immune HealthAlso covers:Immune systemMusclesMetabolism
Tier ⓘ
Members
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
Members
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
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Biohacker Mentions
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Cost per month
$5
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Study, Trial or Testing Result SummaryMembersHuman studies

6 of these 48 human studies gave the ingredient by drip, not by mouth.

study measured biological age directly, but N-acetylcysteine, which this product gives at a dose, has human trials on oxidative stress, a common aging marker. In 120 men, 600 mg daily for 3 months antioxidant capacity and oxidative stress compared with placebo. …

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Review Totals and SummaryMembers19,702 reviews
19,702 reviews · IHerb 16,125 · Walmart 2,287 · Swanson 1,093 · Lifeextension 102 · Amazon 88 · Vitacost 7

With a substantial user base and overall ratings, Life Extension Glycine and N-Acetyl-L-Cysteine has carved out a reputation for of its consumers. reviewers express with the supplement, frequently describing it as a reliable addition to their wellness routines. …

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Biohacker SummaryMembersWhat our biohacker panel says

The main ingredient here is N-acetylcysteine (the cysteine source), and the panel leans : of ten, five it, two use it, and one , with two staying . People take it mainly to support glutathione, the body's key antioxidant, and for oxidative stress, with other uses named including calming inflammation, glutamate spikes, breaking up bacterial biofilms, and handling heavy air pollution. …

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RAL SummaryMembersThe tier and why

study measured biological age directly. …

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More DetailsMembersBody systems · Combine with · Possible side effects

Body systems: Immune system, Muscular system, Metabolic system, Reproductive system. Combine with and possible side are for members.

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Supplement FactsN-Acetyl-L-Cysteine 1800 mg · Glycine 1800 mg
Supplement Facts
Serving Size 1 Scoop
Servings Per Container none
Amount Per Serving% Daily Value
N-Acetyl-L-Cysteine (free-form)1,800 mg†
Glycine (free-form)1,800 mg†
† Daily Value not established.

Directions: 1 capsule daily

Label source: the brand's label · Report a label change

Where to BuyLife Extension · Amazon · Swanson
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We sell no supplements. Prices change; check the store.

Graded October 23, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.