Life Extension Hair, Skin & Nails Collagen Plus Formula Review

The Life Extension Hair, Skin & Nails Collagen Plus Formula is a best-in-class and best-selling nutritional supplement designed to support lasting beauty from within. This formula, available in 120 tablets, is packed with clinically studied nutrients that promote collagen and keratin health, essential for youthful and healthy hair, skin, and nails. It specifically encourages healthy hair, skin, and nail growth, supports skin suppleness and elasticity, and is clinically shown to promote overall collagen and keratin health. Key ingredients include VERISOL® Bioactive Collagen Peptides®, Cynatine® HNS, Biotin, and Silicon. VERISOL® Bioactive Collagen Peptides® work to support the skin’s extracellular matrix by stimulating collagen and elastin formation and inhibiting their breakdown. This action helps to enhance skin suppleness, elasticity, growth, repair, thickness, hydration, and resilience to sunlight. Clinical research has demonstrated that these peptides can lead to a significant minimization in eye wrinkle volume, increased skin elastin and collagen, and support healthy nails by maintaining their growth rate and preventing chipping and breakage. Cynatine® HNS provides solubilized keratin, along with a blend of zinc, vitamins B3, B5, B6, copper, and biotin. These components are vital for promoting keratin formation, which is a cornerstone for strong hair, skin, and nails. Studies on Cynatine® have shown a reduction in the appearance of wrinkles and an improvement in hair brightness and luster. Biotin is included for its crucial role in the metabolism of proteins and fatty acids, which are fundamental for healthy skin, hair, and nails. Additionally, Silicon, a mineral, is incorporated to maintain healthy collagen and contribute to strong, youthful hair, skin, and nails, while also aiding in the transfer of calcium into bone. This innovative formula works synergistically to rejuvenate hair and skin, reduce the appearance of fine lines and wrinkles, and promote healthy keratin formation. It maintains the essential proteins and compounds responsible for healthy hair and skin, offering a comprehensive approach to beauty and wellness. The product is gluten-free and non-GMO, reflecting Life Extension's commitment to science-backed health solutions for those seeking to improve their appearance and combat signs of aging.

Product Focus: Hair GrowthAlso graded for:Joints and MobilityYounger-Looking Skin for WomenAlso covers:Skin
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$25
Study, Trial or Testing Result SummaryMembersHuman studies

3 of these 47 human studies gave the ingredient by injection, not by mouth.

The support comes from a placebo-controlled trial of 50 women who took 500 milligrams of a soluble keratin with vitamins and minerals for 90 days. They had hair and nail measures than the placebo group. …

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Review Totals and SummaryMembers8,480 reviews
8,480 reviews · IHerb 6,513 · Amazon 1,103 · Walmart 419 · Life Extension 229 · Swanson Vitamins 214 · SupplementFirst 1 · Vitacost 1

This "Life Extension Hair, Skin & Nails Collagen Plus Formula" has garnered approximately 8480 ratings across various stores, with a of users expressing . A remarkable of star ratings are 4 or 5 stars, indicating a reception. **What Buyers Say It Did For Them** customers report in their hair and nails. …

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Biohacker SummaryMembersWhat our biohacker panel says

Keratin, the main ingredient, drew only three comments from the panel, so there is real group view on it. One noted that hair protein is made of sulfur, one pointed to a wool-based keratin scaffold said to beat collagen for bone regeneration, and one questioned whether a keratin joint supplement without water. …

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RAL SummaryMembersThe tier and why

A placebo-controlled trial of 50 women found that the same 500 milligram keratin, combined with vitamins and minerals, hair and nails. …

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More DetailsMembersBody systems · Combine with · Possible side effects

Body systems: Skin, hair and nails. Combine with and possible side are for members.

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Supplement FactsNiacin 18 mg · Vitamin B6 2 mg · Biotin 2500 mcg
Supplement Facts
Serving Size 4 Tablets
Servings Per Container 30
Amount Per Serving% Daily Value
Niacin (as niacinamide)18 mg113%
Vitamin B6 (as pyridoxine HCl)2 mg118%
Biotin2,500 mcg8333%
Pantothenic acid (as D-calcium pantothenate)13.68 mg
Calcium (as dicalcium phosphate)83 mg
Zinc (as zinc oxide)15 mg
Copper (as copper sulfate)1.65 mg
VERISOL® Bioactive Collagen Peptides®2,500 mg†
Cynatine® HNS (providing solubilized keratin)500 mg†
Silicon [from std. bamboo extract (stem)]3 mg†
† Daily Value not established.

Directions: Take four (4) tablets daily, or as recommended by a healthcare practitioner.

Barcode (UPC) 737870232216 · Label source: the brand's label · Report a label change

Where to BuyLife Extension · Amazon · iHerb
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Graded October 24, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.