Life Extension Hair, Skin & Nails Collagen Plus Formula Review
The Life Extension Hair, Skin & Nails Collagen Plus Formula is a best-in-class and best-selling nutritional supplement designed to support lasting beauty from within. This formula, available in 120 tablets, is packed with clinically studied nutrients that promote collagen and keratin health, essential for youthful and healthy hair, skin, and nails. It specifically encourages healthy hair, skin, and nail growth, supports skin suppleness and elasticity, and is clinically shown to promote overall collagen and keratin health. Key ingredients include VERISOL® Bioactive Collagen Peptides®, Cynatine® HNS, Biotin, and Silicon. VERISOL® Bioactive Collagen Peptides® work to support the skin’s extracellular matrix by stimulating collagen and elastin formation and inhibiting their breakdown. This action helps to enhance skin suppleness, elasticity, growth, repair, thickness, hydration, and resilience to sunlight. Clinical research has demonstrated that these peptides can lead to a significant minimization in eye wrinkle volume, increased skin elastin and collagen, and support healthy nails by maintaining their growth rate and preventing chipping and breakage. Cynatine® HNS provides solubilized keratin, along with a blend of zinc, vitamins B3, B5, B6, copper, and biotin. These components are vital for promoting keratin formation, which is a cornerstone for strong hair, skin, and nails. Studies on Cynatine® have shown a reduction in the appearance of wrinkles and an improvement in hair brightness and luster. Biotin is included for its crucial role in the metabolism of proteins and fatty acids, which are fundamental for healthy skin, hair, and nails. Additionally, Silicon, a mineral, is incorporated to maintain healthy collagen and contribute to strong, youthful hair, skin, and nails, while also aiding in the transfer of calcium into bone. This innovative formula works synergistically to rejuvenate hair and skin, reduce the appearance of fine lines and wrinkles, and promote healthy keratin formation. It maintains the essential proteins and compounds responsible for healthy hair and skin, offering a comprehensive approach to beauty and wellness. The product is gluten-free and non-GMO, reflecting Life Extension's commitment to science-backed health solutions for those seeking to improve their appearance and combat signs of aging.
Study, Trial or Testing Result SummaryMembersHuman studies
3 of these 47 human studies gave the ingredient by injection, not by mouth.
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Review Totals and SummaryMembers8,480 reviews
Biohacker SummaryMembersWhat our biohacker panel says
RAL SummaryMembersThe tier and why
More DetailsMembersBody systems · Combine with · Possible side effects
Supplement FactsNiacin 18 mg · Vitamin B6 2 mg · Biotin 2500 mcg
| Niacin (as niacinamide) | 18 mg | 113% |
| Vitamin B6 (as pyridoxine HCl) | 2 mg | 118% |
| Biotin | 2,500 mcg | 8333% |
| Pantothenic acid (as D-calcium pantothenate) | 13.68 mg | |
| Calcium (as dicalcium phosphate) | 83 mg | |
| Zinc (as zinc oxide) | 15 mg | |
| Copper (as copper sulfate) | 1.65 mg | |
| VERISOL® Bioactive Collagen Peptides® | 2,500 mg | † |
| Cynatine® HNS (providing solubilized keratin) | 500 mg | † |
| Silicon [from std. bamboo extract (stem)] | 3 mg | † |
Directions: Take four (4) tablets daily, or as recommended by a healthcare practitioner.
Barcode (UPC) 737870232216 · Label source: the brand's label · Report a label change
Graded October 24, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.

