Life Extension NAD+ Cell Regenerator Review

NAD+ Cell Regenerator™ is a Life Extension supplement that provides 300 mg of NIAGEN® nicotinamide riboside per vegetarian capsule. The product is presented as a best-selling NAD supplement and is sold in a bottle of 30 vegetarian capsules, with a suggested use of one capsule daily or as recommended by a healthcare practitioner. The page describes NAD+ as a cellular coenzyme found in every cell of the body. According to the page, NAD+ is necessary to create adenosine triphosphate (ATP), the compound the body uses for fuel. The product is positioned to help maintain youthful levels of NAD+ and to help fight general fatigue at the cellular level. NIAGEN® is described as the first commercially available form of nicotinamide riboside. The page states that NIAGEN® helps encourage the body's production of nicotinamide adenine dinucleotide, also called NAD+. Listed benefits include a clinically studied form of nicotinamide riboside to support energy, support for healthy levels of the coenzyme NAD+, and the role of NAD+ in the production of cellular energy. The Product Details section explains that NAD+ levels have been shown to decline with age, and it cites a randomized controlled trial published in 2019 in which adults taking 300 mg of nicotinamide riboside as NIAGEN® had a 51% increase in blood levels of NAD+ after 2 weeks. The page notes that NIAGEN® is a patented, clinically studied form of nicotinamide riboside, and that NIAGEN® is a registered trademark of ChromaDex, Inc. The product is listed as gluten free, non-GMO and vegetarian. Other ingredients include microcrystalline cellulose, vegetable cellulose for the capsule, silica and vegetable stearate. The page also lists a ConsumerLab Award Approved Quality seal and a 100 mg version sold separately. Warnings on the page advise keeping the product out of reach of children, not exceeding the recommended dose, and consulting a physician when undergoing medical treatment, pregnant or lactating. The page also carries the standard statements that these statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure or prevent any disease.

Product Focus: Healthy AgingAlso covers:Immune systemBrainBreathingMuscles and joints
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$122 at 3 servings

Study, Trial or Testing Result Summary

MembersHuman studies

Each capsule gives 300 mg of nicotinamide riboside. At the three capsules a day members are told to take, that is close to the 1 gram a day used in studies. …

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Review Totals and Summary

Members14,865 reviews
14,865 reviews · Iherb 13,250 · Walmart 586 · Vitaminshoppe 539 · Life Extension 391 · Life Extension Europe 98 · Fruitfulyield 1

Life Extension NAD+ Cell Regenerator capsules have received approximately 1075 ratings across various retail platforms, with a of customers, , awarding them 4 or 5 stars. This supplement is generally viewed by individuals seeking to enhance their energy levels and overall vitality. ** ** users report experiencing notable in their energy and mental clarity after taking these capsules. …

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Biohacker Summary

MembersWhat our biohacker panel says

People who use it say they take it to NAD, a molecule tied to cellular energy, and report energy, recovery, and in one case from arthritis, while one says he notices a big difference when he skips it. Doses mentioned run from 300 milligrams to about a gram a day, and name Niagen as their preferred brand form, with some taking it alongside NMN or CoQ10 or comparing it with plain nicotinamide, which one panelist says is much cheaper. …

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RAL Summary

MembersThe tier and why

More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Cellular metabolism, Immune system, Nervous system, Respiratory system, Musculoskeletal system. Combine with and possible side are for members.

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Supplement Facts

NIAGEN® Nicotinamide Riboside Chloride 300 mg
Supplement Facts
Serving Size 1 vegetarian capsule
Servings Per Container none
Amount Per Serving% Daily Value
NIAGEN® Nicotinamide Riboside Chloride300 mg†
† Daily Value not established.

Other ingredients: Microcrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate.

Directions: Take one (1) capsule daily, or as recommended by a healthcare practitioner. Nicotinamide Riboside does not cause flushing.

Label source: Lifeextension · Report a label change

Where to Buy

Life Extension · Walmart
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Our articles on this subject

Graded October 26, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.