Life Extension Neuro-Mag Magnesium L-Threonate Review

Neuro-Mag® Magnesium L-Threonate is sold by Life Extension as a bottle of 90 vegetarian capsules, presented as a best-selling brain health supplement that supports memory, quick thinking, and cognitive health. The page explains that magnesium is an essential mineral for more than 600 biochemical reactions in the body and plays an important role in the nervous system and brain, and it notes that most Americans do not get enough magnesium from their diet and that suboptimal magnesium levels increase with age. Neuro-Mag® contains clinically studied Magtein® magnesium L-threonate, described as a well-studied and absorbable form of magnesium. The product is positioned to promote working or short-term memory, encourage quick thinking, and support overall cognitive health. The page cites a randomized placebo-controlled trial in 44 adults aged 50 to 70 in which a daily dose of 1.5 to 2 grams of magnesium L-threonate showed improved cognitive and executive function in 12 weeks. The suggested daily dose is three capsules, which provides 2000 mg of magnesium L-threonate and 144 mg of elemental magnesium, and one bottle is listed as a one-month supply of 30 servings. The product is labeled gluten free, non-GMO, and vegetarian, and it is said to be manufactured in the USA. The page states that magnesium L-threonate has less of a laxative effect than other forms of magnesium, and that it can be taken at any time of day with or without food. It also notes that the product was designed for adults over 18. The page says that Life Extension tests raw materials and finished products for heavy metals, microbes, disintegration, and potency, and that a certificate of analysis is available on request. The statements have not been evaluated by the Food and Drug Administration, and the product is not intended to diagnose, treat, cure, or prevent any disease.

Product Focus: Focus and MemoryAlso covers:Brain
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$63 at 2 servings

Study, Trial or Testing Result Summary

MembersHuman studies

4 of these 31 human studies gave the ingredient by drip, not by mouth.

Magnesium L-threonate, the form in this product, has the direct support for thinking and memory. In a 2025 placebo-controlled trial of 100 adults aged 18 to 45 with sleep, 2 grams a day for 6 weeks overall thinking, memory, memory for events and reaction time than placebo, and estimated brain cognitive age was 7.5 years younger, though one reasoning test showed difference. …

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Review Totals and Summary

Members25,628 reviews
25,628 reviews · Amazon 24,775 · Life Extension 733 · Life Extension Europe 120

Across the stores, there are 733 ratings for Life Extension Neuro-Mag Magnesium L-Threonate, and the themes are drawn from the written reviews that could be read on their pages. Despite an overall rating of 4.7 out of 5 stars from 733 reviews, only a set of written feedback was readable on the product page, meaning the insights into customer experiences are drawn from a handful of comments. …

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Biohacker Summary

MembersWhat our biohacker panel says

of the panel or uses magnesium, and sleep is the top reason, with also naming blood pressure, stress, muscle recovery, bone and brain function. Two of them take 400 mg of the threonate form before bed, a third threonate for people who run , and others favor glycinate or blends, often taken in the evening or 90 minutes to 2 hours before bed. …

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RAL Summary

MembersThe tier and why

Placebo-controlled trials of 2 grams a day of magnesium L-threonate, the amount in one serving, memory and thinking, but reviews were counted, so the rules hold it at emerging.

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More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Nervous system. Combine with and possible side are for members.

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Supplement Facts

Magnesium 144 mg
Supplement Facts
Serving Size 3 vegetarian capsules
Servings Per Container 30
Amount Per Serving% Daily Value
Magnesium (from 2000 mg Magtein® magnesium L-threonate)144 mg

Other ingredients: Vegetable cellulose (capsule), microcrystalline cellulose, stearic acid, vegetable stearate, silica.

Directions: Take three (3) capsules daily, or as recommended by a healthcare practitioner.

Label source: Lifeextension · Report a label change

Where to Buy

Life Extension · Amazon
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Our articles on this subject

Graded October 26, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.