MB Herbals Cissus Powder Review

MB Herbals Cissus Powder is a premium herbal supplement derived from the stem of *Cissus quadrangularis*, a succulent vine belonging to the Vitaceae family, widely recognized in traditional healing systems like Ayurveda. Known as "Hadjod" in Indian Ayurvedic texts, as well as Asthisanghata, Kandavalli, and Vajrangi, this plant has been revered for centuries for its profound medicinal properties, particularly concerning bone and joint health. MB Herbals ensures a pure product, consisting of 100% *Cissus quadrangularis* Stem Powder, free from preservatives, additives, GMOs, and gluten. The efficacy of *Cissus quadrangularis* is attributed to its rich phytochemical profile, which includes flavonoids, triterpenoids, phytosterols, glycosides, carotenoids, tannins, phenols, calcium, and vitamin C. These bioactive compounds work synergistically to exert a range of pharmacological activities within the body. Primarily, *Cissus quadrangularis* is celebrated for its potent anti-inflammatory, analgesic (pain-reducing), and antioxidant properties. One of the most significant mechanisms involves its role in bone metabolism and regeneration. The plant's constituents, including anabolic meds, are believed to influence gene expression related to bone remodeling, promoting osteoblast proliferation (bone formation cells) and enhancing the differentiation of mesenchymal stem cells into osteoblastic lineages. This action accelerates the early generation of connective tissue, leading to faster healing of fractures and potentially reducing bone loss associated with conditions like osteoporosis. Studies suggest it can restore normal bone composition more quickly than natural healing alone. Furthermore, *Cissus quadrangularis* acts as a natural anti-inflammatory agent by suppressing specific inflammatory pathways and reducing levels of inflammatory markers such as TNF-α. This mechanism contributes to its ability to alleviate joint pain and swelling, making it beneficial for individuals suffering from arthritis and other inflammatory joint conditions. Its analgesic properties can provide relief from both acute and chronic pain, sometimes within as little as 30 minutes of ingestion. Beyond musculoskeletal support, *Cissus quadrangularis* has demonstrated potential in metabolic health. It may aid in weight management by influencing appetite control and enhancing fat metabolism, with some studies observing reductions in body weight, body fat, and improvements in blood parameters like fasting blood sugar, triglycerides, and cholesterol levels. The plant also exhibits hepatoprotective activity, potentially due to its antioxidant properties, and has shown anti-ulcerative effects, protecting the gastrointestinal lining. The recommended dosage for MB Herbals Cissus Powder is typically 1g to 3g daily, divided into two doses.

Product Focus: Joints and Mobility
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Study, Trial or Testing Result SummaryMembersHuman studies

11 of these 33 human studies gave the ingredient by drip or injection, not by mouth.

This product is sold as pure Cissus stem powder, and the label lists only amounts of minerals per serving. We were given studies on Cissus itself, so this summary covers only those minerals, and of them is present at a studied dose. …

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Review Totals and SummaryMembers90 reviews
90 reviews · Mbherbals 90

MB Herbals Cissus Powder has garnered about 90 ratings across various online stores, generally receiving a response. A of customers, of those who provided star ratings, awarded the product 4 or 5 stars. **What Buyers Say It Did For Them** customers reported , particularly joint and bone recovery. …

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Biohacker SummaryMembersWhat our biohacker panel says

ten members of our panel either use or zinc, the main ingredient in this product. They highlight its for immunity, testosterone, sperm , mood, longevity, sleep, joint , skin, and the gut lining. …

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RAL SummaryMembersThe tier and why

This tier rests mainly on buyer reviews, with of 90 ratings and every written review that mentioned joints saying it . The supporting zinc study is because it pooled zinc with other supplements and did test zinc alone.

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More DetailsMembersBody systems · Combine with · Possible side effects

Body systems: Musculoskeletal system. Combine with and possible side are for members.

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Supplement FactsTotal Calories 0 · Carbohydrate 1 g · Fat 40 mg
Supplement Facts
Serving Size 2g
Servings Per Container 113
Amount Per Serving% Daily Value
Total Calories00%
Carbohydrate1 g0.3%
Protein250 mg0.5%
Fat40 mg0.1%
Dietary Fibre25 mg0.1%
Calcium36 mg1.5%
Phosphorus37 mg3.7%
Potassium18 mg0.8%
Zinc2 mg0.2%
Magnesium3 mg0.6%
Iron2 mg25%
* Percent Daily Values are based on a 2,000 calorie diet.

Directions: 2g with water once daily.

Label source: Amazon · Report a label change

Where to BuyMB Herbals · Amazon · Silkrute
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Graded October 24, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.