Niance Epigen12 Cell Renewal Review

EPIGEN12 Cell Renewal is presented by Niance as a longevity supplement designed to turn back the biological clock by up to 12 years. The page describes it as a formula that addresses 12 out of 14 hallmarks of aging at a cellular level. The main active is a proprietary EPIGEN12 extract, described as a next-generation, flavonoid-rich extract from scarlet beebalm and lemon balm. According to the page, the formula is enhanced with Trans-Resveratrol for bioavailability and combines Nicotinamide Riboside with Niacinamide, which together are said to support DNA repair, boost NAD+ levels and defend against oxidative stress. The product is positioned as reducing epigenetic aging, preserving telomere length, revitalising mitochondrial energy production, preventing cellular senescence, supporting vascular health through endothelial function and nitric oxide release, and providing antioxidant protection. The page states that these claims are supported by an 81-participant, randomised, double-blind, placebo-controlled study in which participants aged 45 to 65 took 100 mg of EPIGEN12 over 12 weeks. Reported outcomes include improved leukocyte telomere length, enhanced quality of life with better physical activity and sleep indices compared with placebo, and a reduction in biological aging markers. The page also lists laboratory studies covering DNA methylation age, telomere shortening rate, mitochondrial ATP production in human heart cells, nitric oxide release in endothelial cells, and a nematode healthspan study. A separate 12-week consumer perception study, which the page says is self-reported, lists improvements in vitality, sleep, mental agility and physical recovery. Each capsule is listed with Nicotinamide Riboside 250 mg, EPIGEN12 complex 150 mg, Trans-Resveratrol 100 mg, Niacinamide 16 mg and Coenzyme Q10 15 mg. The product is one capsule daily with a meal, preferably in the morning, for a suggested 6 to 9 months, with the page noting that it is a vegan, Swiss-made product in a bottle of 30 capsules. The page recommends pairing it with a balanced diet and healthy lifestyle and says it is designed to be used alongside other Niance products such as the Collagen-Hyaluron Beauty Booster and GENR8 Biotic supplements. The page states that the product is developed and manufactured in Switzerland in Swissmedic-certified facilities, and that it is gmo free, mineral oil free, sensitizer free, PEG free and clean beauty. It also says the product is not a replacement for a healthy lifestyle and that results on biological age are assessed over months through biomarker testing.