NOW Foods D-Mannose 500 mg Review

D-Mannose Urinary Support 500 mg Veg Capsules from NOW Foods is listed under Healthy Urinary Tract. The page describes the product as beige with speckles, and notes that natural color variation may occur. The main claim is Cleanses the Bladder. D-mannose is described as a naturally occurring simple sugar that the body uses to help cleanse the urinary tract and maintain a healthy bladder lining. The page states that it is metabolized only in small amounts, with excess amounts rapidly excreted in urine, so it will not interfere with healthy blood sugar regulation. Clinical studies are cited as demonstrating that, when taken regularly, D-mannose promotes normal urinary tract function by cleansing and maintaining the health of the bladder lining. The product is sold in four sizes: 60 veg capsules at $16.99 with 20 servings, 100 veg capsules at $27.99 (in stores only) with 33 servings, 120 veg capsules at $31.99 with 40 servings, and 240 veg capsules at $59.99 with 80 servings. Each serving is 3 veg capsules and provides 1.5 g (1,500 mg) of D-mannose, with 10 calories, 2 g total carbohydrate and 2 g total sugars per serving. Suggested usage is to take 3 capsules 1 to 3 times daily with water or unsweetened juice, such as unsweetened cranberry juice. The label says to store in a cool, dry place after opening. The caution section says the product is for adults only, and that adults should consult a physician if pregnant or nursing, taking medication, or having a medical condition, and to keep out of reach of children. Other ingredients are hypromellose cellulose capsule, rice flour, stearic acid from a vegetable source, magnesium stearate from a vegetable source and silicon dioxide. The page says it is not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients, but is produced in a GMP facility that processes other ingredients containing these allergens. Certifications and labels listed include Halal, Intertek GMP Supplement Certification, Kosher Triangle K, Non-GMO Project Verified, Vegan, Made without Dairy, Made without Eggs, Gluten Free, Made without Nuts, Made without Soy and Vegan or Vegetarian. The page notes the product received a 2018 Taste for Life Essentials Award. It is made and quality tested in the USA with globally sourced ingredients. The company describes itself as family and employee owned, and the bottle is made from 100 percent PCR post-consumer recycled resin. The page carries the standard disclaimer that these statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure or prevent any disease. The product is listed under Other Supplement Products and the page rating is 4.5 from 11 ratings.

Product Focus: Kidney Health
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Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$25

Study, Trial or Testing Result Summary

MembersHuman studies

human study measured kidney function directly. The studies looked at urinary infections, which can reach the kidneys. …

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Review Totals and Summary

Members534 reviews
534 reviews · Walmart 414 · Pureformulas 74 · Gnc 18 · NOW Foods website 11 · Cvs 10 · Lifeextension 7

NOW Foods D-Mannose 500 mg capsules are -received by customers, garnering approximately 425 ratings across various stores, with an impressive of star ratings being 4 or 5. Buyers consistently highlight its effectiveness in supporting urinary tract . **What it does for buyers** Customers primarily use these D-Mannose capsules for and addressing urinary tract infections (UTIs). …

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Biohacker Summary

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RAL Summary

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More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Urinary system, Kidneys. Combine with and possible side are for members.

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Supplement Facts

D-Mannose 1.5 g (1,500 mg)
Supplement Facts
Serving Size 3 Veg Capsules
Servings Per Container 20
Amount Per Serving% Daily Value
Calories10
Total Carbohydrate2 g1%
Total Sugars2 g
D-Mannose1.5 g (1,500 mg)
* Percent Daily Values are based on a 2,000 calorie diet.

Other ingredients: Hypromellose (cellulose capsule), Rice Flour, Stearic Acid (vegetable source), Magnesium Stearate (vegetable source) and Silicon Dioxide.

Directions: Take 3 capsules 1 to 3 times daily. Take with water or unsweetened juice, such as unsweetened cranberry juice.

Label source: Nowfoods · Report a label change

Where to Buy

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Graded October 26, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.