Reverse Age Lab Logo
Source Naturals Guggulsterones 37.5 mg - 60 Tablets bottle
+ Add to ProtocolAsk Rala about it

Source Naturals Guggulsterones 37.5 mg - 60 Tablets Review

Source Naturals Guggulsterones deliver natural support for maintaining cholesterol levels that are already within the normal range. These plant compounds act at the farnesoid X receptor (FXR) to aid in the conversion of cholesterol into bile‚ a key process in cholesterol management. Guggulsterones also enhance thyroid activity‚ further supporting healthy cholesterol regulation by the liver.

Product Focus: Thyroid HealthAlso covers:HormonesDigestionSkin
Tier ⓘ
Members
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
Members
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Members
Biohacker Mentions
Members
Cost per month
$14
+ Add to ProtocolAsk Rala about it

Study, Trial or Testing Result Summary

MembersHuman studies

Direct evidence that guggul thyroid is . In a trial of 100 adults with an underactive thyroid, a four-herb formula that includes guggul, taken at 20 grams a day for about 60 days alongside standard thyroid hormone medicine, thyroid-stimulating hormone than the medicine alone, and free thyroid hormone levels rose. …

Members see the full analysis, checked against their own meds and goals. Start My 7-Day Free Trial →

Review Totals and Summary

Members112 reviews
112 reviews · Amazon 110 · EBay 2

Real users of Guggulsterones 37.5 mg - 60 Tablets consistently report a remarkable level of with their experiences, as reflected in reviews across major platforms like Amazon and eBay. People frequently this product for its effectiveness, often noting that they feel a noticeable difference shortly after starting their regimen. …

Members see the full analysis, checked against their own meds and goals. Start My 7-Day Free Trial →

Biohacker Summary

MembersWhat our biohacker panel says

Our biohacker panel has discussed this product yet.

Members see the full analysis, checked against their own meds and goals. Start My 7-Day Free Trial →

RAL Summary

MembersThe tier and why

The tier rests on a controlled trial of 100 people with an underactive thyroid in which a four-herb formula containing guggul thyroid hormone results alongside standard medicine, together with 112 counted reviews being . Guggul was tested alone, so its own is uncertain.

Members see the full analysis, checked against their own meds and goals. Start My 7-Day Free Trial →

More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Endocrine system, Digestive system, Skin. Combine with and possible side are for members.

Members see the full analysis, checked against their own meds and goals. Start My 7-Day Free Trial →

Supplement Facts

Guggul Gum Extract Yielding 37.5 mg Guggulsterones 375 mg
Supplement Facts
Serving Size 1 Tablet
Servings Per Container 60
Amount Per Serving% Daily Value
Guggul Gum Extract (10%) Yielding 37.5 mg Guggulsterones375 mg†
† Daily Value not established.

Directions: 1 tablet twice daily between meals.

Barcode (UPC) 021078018391 · Label source: the brand's label · Report a label change

Where to Buy

Amazon · Walmart · Target
AmazonBuy ↗
WalmartBuy ↗
TargetBuy ↗

We sell no supplements. Prices change; check the store.

More thyroid health products

MembersThe highest ranked for the same goal
  • Tier
  • Tier
  • Tier

All thyroid health supplements, ranked

Members see the products, their ranking and the reasons. Start My 7-Day Free Trial →

Read more

Our articles on this subject

Graded October 23, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.