The Vitamin Shoppe Active-C with Bioflavonoids 500 MG Review
The Vitamin Shoppe Active-C with Bioflavonoids 500 MG is a dietary supplement meticulously formulated to deliver comprehensive immune support and potent antioxidant benefits. At its core, this supplement provides 500 milligrams of Vitamin C, a crucial water-soluble vitamin essential for numerous physiological functions within the human body. Beyond its primary ascorbic acid component, this advanced formulation is enhanced with a synergistic blend of citrus bioflavonoids, rutin, rose hips, acerola, and mineral ascorbates including calcium, magnesium, and zinc, all designed to optimize absorption and efficacy. Vitamin C, or ascorbic acid, functions natively as a powerful antioxidant, meaning it neutralizes harmful free radicals that can cause oxidative stress and cellular damage throughout the body. This protective action is vital for maintaining cellular integrity and overall health. Furthermore, Vitamin C plays a pivotal role in promoting natural immunity by supporting various cellular functions of the immune system. It is integral to the production and function of white blood cells, particularly phagocytes and lymphocytes, which are critical for identifying and eliminating pathogens. Beyond its immune and antioxidant properties, Vitamin C is indispensable for collagen formation. Collagen is the most abundant protein in the body, forming the structural framework of skin, bones, cartilage, blood vessels, and connective tissues. By facilitating collagen synthesis, Vitamin C contributes to wound healing, skin elasticity, and the maintenance of healthy joints and bones. Additionally, it significantly enhances the absorption of non-heme iron, the form of iron found in plant-based foods, which is crucial for preventing iron deficiency and supporting healthy red blood cell production. The inclusion of bioflavonoids, such as those derived from citrus, rutin, rose hips, and acerola, is a key differentiating factor in this Active-C formulation. Bioflavonoids are plant compounds that naturally occur alongside Vitamin C in fruits and vegetables. They are believed to work synergistically with Vitamin C, enhancing its absorption and bioavailability within the body. While the exact mechanisms are still being researched, bioflavonoids are thought to protect Vitamin C from oxidation, thereby prolonging its activity and ensuring more of the vitamin is utilized by the body. They also possess their own antioxidant and anti-inflammatory properties, further contributing to the supplement's overall health benefits, including supporting capillary and blood vessel integrity and promoting cardiovascular health. The mineral ascorbates (calcium, magnesium, zinc) present in the formula are designed to provide a buffered form of Vitamin C, which can be gentler on the stomach for individuals who might experience digestive discomfort with traditional ascorbic acid. Zinc, in particular, is another essential mineral known for its critical role in immune function, further bolstering the supplement's capacity to support the body's natural defenses. This comprehensive blend ensures that the 500 mg of Vitamin C is not only delivered effectively but also absorbed efficiently, making it a suitable choice for individuals seeking daily wellness support and enhanced immune resilience.
Study, Trial or Testing Result SummaryMembersHuman studies
6 of these 124 human studies gave the ingredient by drip, not by mouth.
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Supplement FactsVITAMIN C - 500 MG · CALCIUM - AND CALCIUM CARBONATE)) 60 MG · MAGNESIUM - ) 10 MG
| VITAMIN C - (AS ACTIVE C (TRI-SCORB PROPRIETARY BLEND (AS CALCIUM ASCORBATE, MAGNESIUM ASCORBATE, ZINC ASCORBATE) | 500 MG | 556% |
| CALCIUM - (AS ACTIVE C™ (AS TRI-SCORB™ PROPRIETARY BLEND (AS CALCIUM ASCORBATE, MAGNESIUM ASCORBATE, AND ZINC ASCORBATE) AND CALCIUM CARBONATE)) | 60 MG | 5% |
| MAGNESIUM - (AS ACTIVE C™ (AS TRI-SCORB™ PROPRIETARY BLEND (AS CALCIUM ASCORBATE, MAGNESIUM ASCORBATE, AND ZINC ASCORBATE)) | 10 MG | 2% |
| ZINC - (AS ACTIVE C™ (AS TRI-SCORB™ PROPRIETARY BLEND (AS CALCIUM ASCORBATE, MAGNESIUM ASCORBATE, AND ZINC ASCORBATE)) | 2 MG | 18% |
| CITRUS BIOFLAVONOIDS STD. FOR 50% HESPERIDIN 100 MG | 111 MG | |
| RUTIN | 25 MG | |
| ROSE HIPS EXTRACT 4:1 | 20 MG | |
| ACEROLA 4:1 EXTRACT | 20 MG | |
| BLACK PEPPER - 12:1 EXTRACT (PIPER NIGRUM L.)(FRUIT) | 5 MG |
Directions: Take one (1) tablet daily, preferably with a meal.
Label source: The Vitamin Shoppe · Report a label change
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Graded October 23, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
