Thorne Magnesium Bisglycinate Review

Thorne Magnesium Bisglycinate is presented as a powdered formula designed to promote restful sleep and muscle relaxation, making it an ideal supplement for active individuals seeking to unwind. This lightly sweetened powder is noted for being well-tolerated and optimally absorbed, and it carries the NSF Certified for Sport® designation, ensuring rigorous testing for purity and label accuracy, which is particularly beneficial for athletes. The product supports the health of the heart, blood vessels, brain, bones, muscles, and lungs, while also aiding in healthy sugar metabolism, maintaining normal blood pressure, and facilitating energy production. Its bisglycinate form is specifically bound to glycine, a calming neurotransmitter, which makes it especially suitable for pre-bedtime use to help users relax and prepare for sleep. This gentle formulation is less likely to cause the laxative effects often associated with other types of magnesium supplements. Magnesium itself is a vital mineral involved in over 600 enzymatic reactions within the body. The text highlights that a significant portion of U.S. adults may not meet the recommended daily intake of magnesium, leading to potential issues such as inefficient blood sugar metabolism, muscle cramps, fatigue, and poor sleep. Thorne Magnesium Bisglycinate aims to address these deficiencies by providing essential support for the electrical activity of the heart, promoting normal heart rate and rhythm, and helping to relax both smooth and skeletal muscles. It also encourages the dilation of blood vessels, which contributes to maintaining normal blood pressure and enhancing blood flow, alongside supporting insulin sensitivity and acting as a cofactor for enzymes crucial in cellular energy production. The product is available in a great-tasting powder that can be easily mixed with water, juice, or other powdered supplements, offering a convenient alternative to capsules. It is also noted that magnesium bisglycinate is synonymous with magnesium glycinate, with 'bisglycinate' being a more precise term due to the presence of two glycine molecules. For athletes, the NSF Certified for Sport® status is a critical feature, as it guarantees that every batch is tested for compliance with label claims and the absence of nearly 300 substances banned by major athletic organizations, providing peace of mind regarding supplement integrity. The product is designed to support relaxation, healthy heart, muscle, and sugar metabolism, and optimal sleep quality. Thorne emphasizes its comprehensive testing for identity, purity, and potency of each ingredient, including checks for contaminants like heavy metals, pesticides, and harmful microbes. For best results in supporting sleep, it is recommended to take Thorne Magnesium Bisglycinate 30-60 minutes before bedtime as part of an evening routine, with results varying depending on individual health and consistent use.

Product Focus: SleepAlso graded for:Blood SugarOccasional Heartburn: Fast ReliefHealthy AgingAlso covers:BrainMuscles and joints
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$26
Study, Trial or Testing Result SummaryMembersHuman studies

6 of these 53 human studies gave magnesium by drip, not by mouth.

This product gives 200 milligrams of magnesium a day, which counts as a dose. The study results for sleep are , and any appears . …

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Review Totals and SummaryMembers3,410 reviews
3,410 reviews · Amazon 2,600 · Thorne 810

Thorne Magnesium Bisglycinate is widely regarded by customers, particularly active individuals, for its impact on sleep quality and overall mood. Users consistently report that this powdered formula effectively promotes restful sleep, them to unwind and relax, especially when taken before bedtime. …

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Biohacker SummaryMembersWhat our biohacker panel says

The common reason is sleep, followed by blood pressure, bone , brain function, and fixing levels. On forms, three panelists like glycinate for calming and sleep, while three others take or suggest threonate, and two of them take 400 mg before bed. …

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RAL SummaryMembersThe tier and why

The rules placed this at the tier because the trials and the latest review found reliable sleep from magnesium, with trials in sleepers and older adults and a review rating the evidence and certainty.

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More DetailsMembersBody systems · Combine with · Possible side effects

Body systems: Nervous system, Musculoskeletal system. Combine with and possible side are for members.

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Supplement FactsMagnesium 200 mg
Supplement Facts
Serving Size 1 Scoop (5.9 g)
Servings Per Container 30
Amount Per Serving% Daily Value
Magnesium (as Magnesium Bisglycinate)200 mg48%

Barcode (UPC) 693749006442 · Label source: Blueskyvitamin · Report a label change

Graded October 23, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.