Tru Niagen 300 mg Review

Our foundational 300mg daily serving is clinically shown to increase NAD+ levels by over 50% in most individuals. Tru Niagen gives you the daily support you need to help your body manage the cellular demands of aging and stressors such as poor diet, excess alcohol consumption, overtraining, a sedentary lifestyle, immune stress, and excess sun exposure. Our award-winning, key ingredient, Niagen® NR (nicotinamide riboside), is backed by world-leading researchers, and currently over 75% of published peer-reviewed clinical studies on NR use Niagen® NR. Made in the U.S. with globally sourced components. The page lists several recognitions: Tru Niagen 300mg won the Consumer Choice Award as a top supplement for everyday wellness and cellular vitality; it earned the Most Beloved Brand title in 2023; Niagen was honored as the 2024 Healthy Aging Ingredient of the Year; and the product is tested by SuppCo certified, with active ingredients independently verified by ISO 17025 accredited labs. How to use: adults can take one capsule one to three times daily as needed or as recommended by a healthcare professional. Tru Niagen is meant to be taken daily, and depending on lifestyle, stressors and diet, an additional capsule can be added. It is stated to be safe to consume up to 2,000mg per day. Function: Niagen, the patented nicotinamide riboside, is described as clinically shown to increase NAD+ more efficiently than other NAD+ precursors. The page says nicotinamide riboside boosts NAD+ to support cellular function, energy production and cellular repair, and supports cellular health, muscle health and heart health, as well as healthy aging for people with active lifestyles, age-related concerns and additional lifestyle stressors. The Ingredients section describes Niagen as a patented, safety-reviewed form of nicotinamide riboside that is shown to pass through cell walls. The product is labelled vegetarian, formulated without gluten or major allergens, halal, kosher, safety-tested and FDA-notified. Serving size is one vegetarian capsule. Supplement Facts show 300mg of NIAGEN nicotinamide riboside chloride per capsule, with a Daily Value not established. Caution: if pregnant, nursing or taking medications, seek advice from a healthcare professional before use, and the product is not intended for children under 18. The page states that the statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure or prevent any disease.

Product Focus: Healthy AgingAlso covers:BrainMusclesImmune systemBreathing
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$147 at 3 servings

Study, Trial or Testing Result Summary

MembersHuman studies

Nicotinamide riboside, the only active ingredient here, reliably blood levels of a cell energy molecule that falls with age. In a placebo-controlled trial of overweight adults, 300 milligrams a day of this exact form that molecule by about half within 2 weeks, with side than placebo. …

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Review Totals and Summary

Members622 reviews
622 reviews · Tru Niagen website 622

Across the stores, Tru Niagen 300 mg has accumulated 622 ratings, with the themes drawn from the written reviews that could be read on their pages. Customers frequently Tru Niagen 300 mg for its impact on their energy levels and overall -being. …

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Biohacker Summary

MembersWhat our biohacker panel says

Nicotinamide riboside is the main ingredient here, and the panel leans toward using it, though firmly. Doses are rarely given: one panelist takes 300 mg, another a gram, and a third cites about a gram a day from trials, while one advises following the bottle label. …

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RAL Summary

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More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Cellular metabolism, Nervous system, Muscular system, Immune system, Respiratory system. Combine with and possible side are for members.

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Supplement Facts

NIAGEN® 300 mg
Supplement Facts
Serving Size 1 Vegetarian Capsule
Servings Per Container 90
Amount Per Serving% Daily Value
NIAGEN® (nicotinamide riboside chloride)300 mg†
† Daily Value not established.

Label source: Truniagen · Report a label change

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Our articles on this subject

Graded October 26, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.