Lactase: benefits by goal, the dosage that worked, and the supplements ranked

What the 11 human studies of lactase we graded show for each goal, the dose that worked, and the products that hold it. This page is educational, not medical advice.

Human studies graded
11
Goals with an improvement
0
Products
0
Ranked
–
Biohacker opinions
6/10

Lactase benefits, by goal: what the studies show

Members OnlyThe top 1 of 1 goals
GoalWhat the studies showStudiesDose that worked
After-Meal Comfort: Fast ReliefToo few studies 11 studies, 4 showed an improvement, 1 found none116,000 IU

Lactase supplements, ranked by the human studies

Members OnlyNone in our catalog yet

No product in our catalog holds it at a dose that counts yet.

Lactase dosage: how much per day

The dose that worked in the studies, and the upper limit

The studies taken by mouth that showed an improvement gave 6,000 to 9,900 IU a day.

Biohacker panel

Members OnlyWhat our 10 biohackers say about lactase
Recommend or use it3 of 10

Dave Asprey, 25 Dec 2025: Recommends leaving Santa some enzyme support from MassZymes because 70% of adults lack the enzyme lactase to properly digest dairy. Source

Ben Greenfield, 20 Nov 2024: Discusses how the lactase enzyme might affect digestion. Source

Dr. Eric Berg, 29 Jun 2024: Explains that lactase is an enzyme that helps break down milk sugar (lactose) and is destroyed during pasteurization, but is present in raw dairy. Source

Peter Attia, 31 Oct 2023: Explains that people take lactase milk because if they don't have the lactase enzyme, they can't break down lactose sugar in milk, leading to food sensitivity symptoms. Source

Dr. Mark Hyman, 26 Mar 2022: Recommends taking a lactase enzyme replacement with a meal if you have lactose intolerance and want to consume dairy or accidentally ingest it. Source

Thomas DeLauer, 15 Jun 2018: Notes that people with lactose intolerance can usually take a lactase enzyme to help break down lactose, but this may warrant further investigation into the body's overall ability to break down milk. Source

What they said, newest first, one statement each.

Questions people ask

Members OnlyAnswered from the figures on this page

How much lactase per day?

The studies taken by mouth that showed an improvement used 6,000 to 9,900 IU a day.

Can I take lactase with my meds?

Some supplements can change how meds work or are absorbed. Members have every product checked against the meds in their Health Profile before it joins their protocol.

Educational, not medical advice. Figures come from the human studies on PubMed we have graded; a study counts for a form when it names the form it used. Updated as new studies arrive. How we grade →