Double Wood Supplements Serrapeptase Review

Serrapeptase is a proteolytic enzyme produced by silkworms with the main function of dissolving the silkworm's cocoon. It is most often supplemented to support joint health but has also been found to liquefy mucus and reduce the size of bacterial biofilms. This makes it helpful for reducing phlegm buildup and nasal discharge. The product carries a Notice that it contains soy and milk, and it is labelled gluten-free and non-GMO. The benefits listed on the page include reducing mucus production, where multiple studies are said to show the enzyme may decrease the viscosity of mucus and help nasal discharge. It is also described as supporting a healthy immune response, and as a systemic proteolytic enzyme that digests certain proteins. Each two capsule serving is stated to contain 240,000 SPU, with each bottle containing 60 servings, which is presented as a two month supply. The brand says it provides pure, potent supplements backed by careful sourcing and rigorous third-party testing. Directions recommend one to two capsules per day, which is 120,000 to 240,000 SPU, taken thirty minutes before eating or two hours after eating, and the page advises not to exceed three capsules per day. The certificate of analysis for lot 2611001 lists a capsule weight of 420 mg, a serrapeptase potency of 233,532 SPU against a specification of 216,000 to 360,000 SPU, a passed disintegration test within 30 minutes, heavy metal results well under limits, and passing microbial tests with E. coli, Salmonella and Staphylococcus aureus absent. The page notes the product is manufactured in an FDA-registered cGMP facility, in the USA from globally sourced materials, and that identity, potency and contaminants are verified per batch. A 30 day money back guarantee is offered. The current listing shows the single bottle as backordered and unavailable, though the price is listed at $19.95. The page also suggests pairing with magnesium products and offers a short frequently asked questions section about timing, dosage and use.

Product Focus: Joints and MobilityAlso covers:Immune system
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$10

Study, Trial or Testing Result Summary

MembersHuman studies

Two human studies tested serrapeptase for ankle joint injuries, and both found swelling. In a 1989 randomized trial of 66 patients after surgery for a torn ankle ligament, those given serrapeptase had about half as much swelling by the third day. …

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Review Totals and Summary

Members121 reviews
121 reviews · Pureformulas 66 · Double Wood Supplements website 24 · Vitacost 2 · Target 1

Across three online stores, Double Wood Supplements Serrapeptase has received a total of 54 ratings, with the following themes drawn from the written reviews visible on their pages, noting that some pages displayed only a handful of comments while others showed . Customers frequently the Double Wood Supplements brand and the overall buying experience. …

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Biohacker Summary

MembersWhat our biohacker panel says

They take it to break down scar tissue, unwanted proteins and biofilms, and some also take it to clotting or stroke , support joints, or with floaters. One panelist describes taking about five big pills every night, roughly a million units, on an empty stomach, and says he has done this for 25 years, while another doses for yeast biofilms. …

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RAL Summary

MembersThe tier and why

The review summary is seller feedback about shipping, pricing, ordering and refunds, and it counts 54 ratings across three stores, which does match the 121 reviews behind the grade, so the review count cannot be taken as reviews of this product. Its reviews are set aside, so it is graded on its studies alone. …

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More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Musculoskeletal system, Immune system. Combine with and possible side are for members.

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Supplement Facts

Serrapeptase 240000 SPU
Supplement Facts
Serving Size 2 Capsules
Servings Per Container 60
Amount Per Serving% Daily Value
Serrapeptase240,000 SPU†
† Daily Value not established.

Other ingredients: Hypromellose (capsule), Rice Flour, Magnesium Stearate and Silicon Dioxide.

Directions: Suggested Use: Take 2 capsules per day. For best results take 30 minutes before a meal or 2 hours after a meal.

Label source: Doublewoodsupplements · Report a label change

Where to Buy

Double Wood Supplements · Vitacost
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Graded October 27, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.