Fleet Laxative Glycerin Suppositories, 50 Count Review

Fleet Laxative Glycerin Suppositories provide gentle, fast-acting relief from occasional constipation. As a hyperosmotic laxative, they work by attracting water into the stool to promote a bowel movement, typically within 15 minutes to an hour.

Product Focus: Regularity: Fast ReliefAlso covers:Digestion
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$0
Study, Trial or Testing Result SummaryMembersHuman studies

This product gives 2 grams of glycerin per suppository. The studies used glycerin enemas at much larger amounts, around 30 milliliters, so it is unclear whether this dose matches what was tested. …

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Review Totals and SummaryMembers2,867 reviews
2,867 reviews · Amazon 1,757 · Walmart 854 · Walgreens 119 · CVS 113 · Fredmeyer 12 · Harristeeter 12

Fleet Laxative Glycerin Suppositories, 50 Count receives generally feedback across major online retailers, with users describing it as a reliable and effective solution for occasional constipation or bowel irregularity. reviewers highlight its quick action, often commenting on fast compared to other methods they’ve tried. …

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Biohacker SummaryMembersWhat our biohacker panel says

Their comments were about teeth and sweetening instead. One panelist that glycerin in dental products coats the teeth and blocks minerals from getting in, which he says leads to teeth that are prone to cavities. …

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RAL SummaryMembersThe tier and why

Rated because placebo-controlled trial supports glycerin for this goal, and in the controlled trials glycerin enemas did than the comparison treatments. The studies also used enemas at far larger amounts than this 2 gram suppository.

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More DetailsMembersBody systems · Combine with · Possible side effects

Body systems: Digestive system. Combine with and possible side are for members.

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Supplement FactsGlycerin 2 g
Supplement Facts
Serving Size 1 suppository
Servings Per Container none
Amount Per Serving% Daily Value
Glycerin2 g†
† Daily Value not established.

Directions: Adults and children, 6 years and over: One suppository, or as directed by a doctor, (per 24 hours). Insert suppository well into rectum.

Label source: Fleetlabs · Report a label change

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More regularity: fast relief productsMembersThe highest ranked for the same goal

Graded October 23, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.