Nature Made Folic Acid 400 mcg Tablets Review
Nature Made Folic Acid 400 mcg Tablets are presented as an important B vitamin for women of childbearing age. Each tablet provides 400 mcg of folic acid, equivalent to 665 mcg DFE. The page explains that folic acid, also known as folate and folacin from dietary sources, helps support the nervous system. It states that it plays a critical role in the proper development of the baby's nervous system, and that adequate folic acid in healthful diets may reduce a woman's risk of having a child with a neural tube defect. The product is described as a little nutritional support for a whole lot of nervous system development. The label lists 665 mcg Folate (400 mcg Folic Acid) and 45 mg Calcium per serving. The serving size is one tablet. The suggested use for adults is one tablet daily with water and a meal. The product is marked as women's health and carries a tablet strength icon of 400 mcg. The page highlights that Nature Made Folic Acid 400 mcg is made from carefully selected ingredients under strict manufacturing processes. It also says the brand is the number one pharmacist recommended letter vitamin brand, based on a U.S. News and World Report and Pharmacy Times survey. The product is United States Pharmacopeia verified, meaning USP has tested and verified ingredients, potency and manufacturing process. Product facts note that folate is sourced from high quality ingredients and can be found in green leafy vegetables. The page lists no artificial flavors, no preservatives, no color added and gluten free. The nutrient shortfalls section notes that only 24 percent of U.S. women of childbearing age consume the recommended intake of folic acid, and that supplementation should begin before conception because the neural tube forms by day 28 of gestation. Good food sources include spinach, lentils, garbanzo beans, and fortified spaghetti or white rice. The interactions section advises consulting a healthcare professional before use if taking medications, and it warns that folic acid should be used with caution with seizure medications such as Dilantin and Mysoline. The page states that folic acid intake from all sources should not exceed 1,000 mcg daily. The product is listed as a one-time purchase at $6.99, with a subscribe and save option at $6.29 per shipment. The product is marked as discontinued and no longer available for purchase on this page.
Study, Trial or Testing Result Summary
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1 of these 18 human studies gave the ingredient by drip, not by mouth.
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Review Totals and Summary
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Biohacker Summary
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Supplement Facts
Folate 665 mcg DFE 665 mcg DFE · Calcium 45 mg
| Folate 665 mcg DFE (400 mcg Folic Acid) | 665 mcg DFE | 166% |
| Calcium (as Calcium Carbonate and Dibasic Calcium Phosphate) | 45 mg | 3% |
Other ingredients: Cellulose Gel, Maltodextrin, Croscarmellose Sodium, Stearic Acid, Magnesium Stearate.
Directions: Adults, take 1 tablet daily with water and a meal.
Label source: Naturemade · Report a label change
Where to Buy
Nature Made · Target · Kroger
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Graded October 28, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.

