Nature Made Folic Acid 400 mcg Tablets Review

Nature Made Folic Acid 400 mcg Tablets are presented as an important B vitamin for women of childbearing age. Each tablet provides 400 mcg of folic acid, equivalent to 665 mcg DFE. The page explains that folic acid, also known as folate and folacin from dietary sources, helps support the nervous system. It states that it plays a critical role in the proper development of the baby's nervous system, and that adequate folic acid in healthful diets may reduce a woman's risk of having a child with a neural tube defect. The product is described as a little nutritional support for a whole lot of nervous system development. The label lists 665 mcg Folate (400 mcg Folic Acid) and 45 mg Calcium per serving. The serving size is one tablet. The suggested use for adults is one tablet daily with water and a meal. The product is marked as women's health and carries a tablet strength icon of 400 mcg. The page highlights that Nature Made Folic Acid 400 mcg is made from carefully selected ingredients under strict manufacturing processes. It also says the brand is the number one pharmacist recommended letter vitamin brand, based on a U.S. News and World Report and Pharmacy Times survey. The product is United States Pharmacopeia verified, meaning USP has tested and verified ingredients, potency and manufacturing process. Product facts note that folate is sourced from high quality ingredients and can be found in green leafy vegetables. The page lists no artificial flavors, no preservatives, no color added and gluten free. The nutrient shortfalls section notes that only 24 percent of U.S. women of childbearing age consume the recommended intake of folic acid, and that supplementation should begin before conception because the neural tube forms by day 28 of gestation. Good food sources include spinach, lentils, garbanzo beans, and fortified spaghetti or white rice. The interactions section advises consulting a healthcare professional before use if taking medications, and it warns that folic acid should be used with caution with seizure medications such as Dilantin and Mysoline. The page states that folic acid intake from all sources should not exceed 1,000 mcg daily. The product is listed as a one-time purchase at $6.99, with a subscribe and save option at $6.29 per shipment. The product is marked as discontinued and no longer available for purchase on this page.

Product Focus: Digestion and BloatingAlso graded for:Mood
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$1

Study, Trial or Testing Result Summary

MembersHuman studies

1 of these 18 human studies gave the ingredient by drip, not by mouth.

trial has tested folic acid alone for everyday gas, bloating or irregularity. The studies pooled six placebo-controlled trials in 624 adults with rheumatoid arthritis taking a med. …

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Review Totals and Summary

Members1,091 reviews
1,091 reviews · Walmart 975 · Target 75 · Kroger 4 · Baker's Plus 4

This Nature Made Folic Acid 400 mcg product has received about 1016 ratings across various stores, with a overall reception; of reviews with stars give it 4 or 5. Customers generally find it effective, affordable, and easy to incorporate into their daily routines. **What it did for them** users report outcomes from taking these tablets. …

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Biohacker Summary

MembersWhat our biohacker panel says

They take it to homocysteine, support mitochondria and brain , and pregnancy, with one noting a child with levels was given it and another noting it has spina bifida. of the prefer methylfolate, an active form the body can use directly, over synthetic folic acid, which is what this product contains. …

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RAL Summary

MembersThe tier and why

The tier rests on trials where folic acid gut side of the drug a med in arthritis patients, which is evidence for everyday gas, bloating or irregularity, and study tested folate for this goal. …

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More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Digestive system, Blood. Combine with and possible side are for members.

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Supplement Facts

Folate 665 mcg DFE 665 mcg DFE · Calcium 45 mg
Supplement Facts
Serving Size 1 Tablet
Amount Per Serving% Daily Value
Folate 665 mcg DFE (400 mcg Folic Acid)665 mcg DFE166%
Calcium (as Calcium Carbonate and Dibasic Calcium Phosphate)45 mg3%

Other ingredients: Cellulose Gel, Maltodextrin, Croscarmellose Sodium, Stearic Acid, Magnesium Stearate.

Directions: Adults, take 1 tablet daily with water and a meal.

Label source: Naturemade · Report a label change

Where to Buy

Nature Made · Target · Kroger
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Graded October 28, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.