Nature's Bounty Milk Thistle 1000mg, Rapid Release Softgels, 50 Count Review

Milk Thistle is a concentrated herb with beneficial antioxidant properties that contribute to overall health and well-being. Milk Thistle has been used in Greek health practices for over 2,000 years. Nature's Bounty Milk Thistle supplements have been traditionally used for liver health. The page lists the label claim Concentrated Herb. Directions: For adults, take one softgel once or twice daily, preferably with a meal. Serving size is 1 softgel, with 50 servings per container. Each softgel provides Milk Thistle Extract 250 mg (Silybum marianum, seed), described as a 4:1 extract equivalent to 1,000 mg whole herb. The Daily Value is not established. Other ingredients are soybean oil, gelatin and vegetable glycerin, with natural caramel color, soy lecithin and titanium dioxide color. The label is marked Non-GMO, with no artificial flavor, artificial sweetener, sugar, starch, milk, lactose, gluten, wheat, yeast or fish, and is sodium free. Warning: if you are pregnant, nursing, taking any medications or have a medical condition, consult your doctor before use. Avoid this product if you are allergic to ragweed or daisylike flowers. Discontinue use and consult your doctor if any adverse reactions occur. Not intended for persons under 18. Keep out of reach of children. Store at room temperature. Do not use if seal under cap is broken or missing. The FAQ advises following the label directions and consulting a doctor or healthcare professional before taking more than recommended. Manufactured by Nature's Bounty, Inc., Bohemia NY 11716 U.S.A.

Product Focus: Liver HealthAlso graded for:Gallbladder and Fat DigestionAlso covers:Digestion
Tier ⓘ
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Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions

Study, Trial or Testing Result Summary

MembersHuman studies

This product gives 500 milligrams a day of milk thistle extract, the 103 milligrams a day that in one trial, so it is at a dose. Silymarin is the active extract of milk thistle. …

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Review Totals and Summary

Members1,042 reviews
1,042 reviews · Hy-vee 564 · Walmart 423 · EBay 25 · Nature's Bounty website 9 · Metro Market 7 · QFC 7 · Pay-Less 7

This Nature's Bounty Milk Thistle 1000mg product has garnered about 478 ratings across various stores, with a of giving it 4 or 5 stars. Overall, customers express with its perceived and of use. **Effectiveness** buyers report , primarily noting support for liver and overall wellness. …

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Biohacker Summary

MembersWhat our biohacker panel says

of the panel milk thistle, with four of the six who spoke leaning and one , and the main reason is liver support and detox, including use around drinking. Doses given were 200 to 400 milligrams of silymarin at 80 percent standardization, 70 to 140 milligrams of silymarin taken 30 to 60 minutes before hot-cold contrast therapy, and 200 milligrams a day for allergy symptoms. …

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RAL Summary

MembersThe tier and why

More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Liver, Digestive system, Metabolism. Combine with and possible side are for members.

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Supplement Facts

Milk Thistle Extract 250 mg
Supplement Facts
Serving Size 1 Softgel
Servings Per Container 50
Amount Per Serving% Daily Value
Milk Thistle Extract250 mg†
† Daily Value not established.

Other ingredients: Soybean Oil, Gelatin, Vegetable Glycerin. Contains <2%>: Natural Caramel Color, Soy Lecithin, Titanium Dioxide Color.

Directions: For adults, take one (1) softgel once or twice daily, preferably with a meal.

Label source: Naturesbounty · Report a label change

Where to Buy

Nature's Bounty · Walmart · Metromarket
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Our articles on this subject

Graded October 28, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.