NOW Foods Serrapeptase 60,000 SPU Review

NOW Serrapeptase Veg Capsules provide 60,000 Units of Activity of serrapeptase, also called serratiopeptidase, per capsule. The page describes serrapeptase as a protein-digesting enzyme isolated from the friendly bacterium Serratia marcescens. The product page states that studies indicate serrapeptase is absorbed intact from the digestive tract and acts systemically to support healthy immune system functions and the body's normal healing processes. The page also notes that some evidence suggests serrapeptase may support respiratory health by helping to maintain normal mucus secretions. The product is listed under Healthy Immune Function and Promotes Respiratory Health, with a note that these statements have not been evaluated by the Food and Drug Administration. Each bottle contains 60 veg capsules, with one capsule per serving and 60 servings per container. The suggested usage is to take 1 capsule daily on an empty stomach with 8 oz. of water. The page advises that continuous use for more than 30 days is not recommended except under physician supervision. Caution notes state that the product is for adults only, is not for long-term use, is not recommended for pregnant or nursing women, and should be discussed with a physician if taking medication, especially meds, or if a medical condition exists. The capsules are vegan, gluten free, and made without dairy, eggs, nuts, soy, and keto friendly. The product is Intertek GMP Supplement Certified. The page states it was made and quality tested in the USA with globally sourced ingredients, and that natural color variation may occur. The company describes itself as family owned since 1968. The capsule color is listed as beige with speckles. Store in a cool, dry place after opening.

Product Focus: Joints and MobilityAlso covers:Immune system
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$13

Study, Trial or Testing Result Summary

MembersHuman studies

Serrapeptase is the only active ingredient here, at 27 milligrams a day, close to the 30 milligrams a day used in studies, so it counts as a dose. Two human studies looked at serrapeptase after ankle injuries, and both found swelling. …

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Review Totals and Summary

Members1,457 reviews
1,457 reviews · IHerb 1,273 · Vitacost 155 · Walmart 16 · Swanson Vitamins 6 · NOW Foods 5 · Ebay 2

NOW Foods Serrapeptase 60,000 SPU capsules are generally very -received by customers, with about 1439 ratings across stores. Of the reviews with stars, give 4 or 5 stars. …

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Biohacker Summary

MembersWhat our biohacker panel says

They take it mainly as an enzyme that breaks down protein, scar tissue and old tissue, and some also mention clotting or stroke , breaking up the slimy layers that bacteria and yeast form, and supporting joints. One panelist takes about five pills every night on an empty stomach, which he puts at about a million units, and he has done so for 25 years. …

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RAL Summary

MembersThe tier and why

The studies cover sudden injuries rather than long-term joint conditions. …

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More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Musculoskeletal system, Immune system. Combine with and possible side are for members.

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Supplement Facts

Serrapeptase 27 mg
Supplement Facts
Serving Size 1 Veg Capsule
Servings Per Container 60
Amount Per Serving% Daily Value
Serrapeptase (60,000 Serratiopeptidase Units)27 mg†
† Daily Value not established.

Other ingredients: Microcrystalline Cellulose, Hypromellose (cellulose capsule), Maltodextrin and MCT (medium-chain triglycerides) Powder. Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Directions: Take 1 capsule daily on an empty stomach with 8 oz. of water. Continuous use of this product for more than 30 days is not recommended except under the supervision of a physician. Store in a cool, dry place after opening.

Label source: Nowfoods · Report a label change

Where to Buy

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Graded October 27, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.