Transparent Labs Creatine HMB Review

Transparent Labs Creatine HMB is presented as an evidence-based step forward for creatine supplementation, which the page says is well known to enhance muscle growth and athletic performance, including muscle endurance and strength. The formula combines creatine monohydrate, described as the most studied form of creatine, with beta-hydroxy-beta-methylbutyrate (HMB), a naturally occurring metabolite that the page says helps reduce muscle damage and muscle protein breakdown. Creatine HMB is also rounded out with BioPerine, an absorption enhancer, and vitamin D3 for comprehensive muscle recovery and support of lean tissue mass. The key ingredients listed are creatine monohydrate at 5,000 mg, myHMB at 1,500 mg, vitamin D3 at 12.5 mcg (500 IU), and BioPerine black pepper fruit extract at 5 mg. The page explains that BioPerine is a standardized extract containing a minimum of 95 percent piperine, so a small dose provides piperine comparable to a much larger amount of ground black pepper, and that it helps increase absorption of the creatine and HMB. The creatine monohydrate section cites the International Society of Sports Nutrition's view that creatine monohydrate is among the most effective ergogenic supplements available, and notes that combining it with resistance training can support performance, lean mass, strength gains, and recovery. The HMB section states that HMB may reduce muscle protein breakdown, accelerate regeneration of skeletal muscle after intense or prolonged exercise, and provide additive effects when combined with creatine. The product is sold as a flavored or unflavored powder in 30 and 60 serving sizes. Directions say to add one level scoop to a shaker with 10 to 12 ounces of cold water, shake until fully dissolved, and consume within 30 minutes after training, or take one scoop in the morning on rest days. The FAQ says cycling is unnecessary, loading is not recommended because of excess vitamin D intake, and one serving daily is the recommended approach. The page also states that the product is third-party tested and offers a 45-day satisfaction guarantee.

Product Focus: Muscle and Strength
Tier ⓘ
Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
Biohacker Mentions
Cost per month
$100 at 2 servings

Study, Trial or Testing Result Summary

MembersHuman studies

2 of these 193 human studies gave the ingredient by drip or injection, not by mouth.

Creatine is the supported ingredient here, at a dose of 5 grams. Combined with strength training, it added about 1.39 kilograms of lean mass over placebo across 61 trials and about 0.82 kilograms across 143 trials. …

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Review Totals and Summary

Members3,431 reviews
3,431 reviews · Transparent Labs (Judge.me reviews) 3,431

Across stores, Transparent Labs Creatine HMB has accumulated 3431 ratings, with the following themes emerging from the written reviews visible on their product pages, which are compared to the total number of ratings. Customers who provide written feedback often describe the product in , terms. …

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Biohacker Summary

MembersWhat our biohacker panel says

of the panel creatine, with about six it, three using it daily, and a staying or cautious. They take it for muscle strength, lean mass, recovery and brain support, and the dose often named is 5 grams a day, usually as creatine monohydrate, with one favoring Creapure powder on fasting days and another taking extra during muscle building phases. …

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RAL Summary

MembersThe tier and why

Human studies support Vitamin D (28 of 55 human studies showed an ), but there are yet reviews to confirm it (0). The final check notes: The tier was justified by vitamin D, a minor ingredient whose own studies show muscle , instead of the main ingredients creatine and HMB; with reviews counted, the tier stays at 4.

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More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Musculoskeletal system. Combine with and possible side are for members.

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Supplement Facts

Total Carbohydrates 1 g · Vitamin D 12.5 mcg (500IU) · Calcium 200 mg
Supplement Facts
Serving Size 1 Scoop (9.5g)
Servings Per Container 30
Amount Per Serving% Daily Value
Calories10
Total Carbohydrates1 g<1%
Vitamin D (as Cholecalciferol)12.5 mcg (500IU)63%
Calcium200 mg16%
Creatine Monohydrate5,000 mg†
β-Hydroxy β-Methylbutyrate (HMB) (as patented myHMB® calcium β-Hydroxy β-Methylbutyrate monohydrate)1,500 mg†
BioPerine® (Black Pepper Extract) (95% Piperine) (Piper nigrum) (fruit)5 mg†
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.

Other ingredients: Citric Acid (920mg), Natural Flavors (700mg), L-Malic Acid (555mg), Stevia Extract (300mg), Beet Root Powder (for color) (40mg).

Label source: Vitacost · Report a label change

Where to Buy

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Graded October 26, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.