Indole-3-carbinol: benefits by goal, the dosage that worked, and the supplements ranked
What the 9 human studies of Indole-3-carbinol we graded show for each goal, the dose that worked, and the products that hold it. This page is educational, not medical advice.
Indole-3-carbinol benefits, by goal: what the studies show
Members OnlyThe top 1 of 1 goals
| Goal | What the studies show | Studies | Dose that worked |
|---|---|---|---|
| Hormone Balance for Women | Improved in studies 9 studies, 3 showed an improvement | 9 | 400 mg |
Indole-3-carbinol supplements, ranked by the human studies
Members OnlyThe top 1 of 1

Indole-3-carbinol dosage: how much per day
The dose that worked in the studies, and the upper limit
The studies taken by mouth that showed an improvement gave 400 mg a day.
Biohacker panel
Members OnlyWhat our 10 biohackers say about Indole-3-carbinol
Dr. Mark Hyman, 21 Dec 2022: Notes that indole-3-carbinol was among the compounds identified to regulate inflammation in a clinical trial. Source
Thomas DeLauer, 26 Jul 2022: Recommends consuming indole-3-carbinol, noting that a 400 mg dose was effective in a study for improving estrogen ratios. Source
Ben Greenfield, 4 Jul 2019: Recommends indole-3-carbinol, found in cruciferous vegetables and supplementation form, for supporting phase one and phase two liver detoxification pathways. Source
Questions people ask
Members OnlyAnswered from the figures on this page
What is Indole-3-carbinol good for?
By the human studies we graded, Indole-3-carbinol shows an improvement for hormone balance for women.
Indole-3-carbinol for hormone balance for women: what do the studies show?
In the human studies of Indole-3-carbinol we graded for hormone balance for women: 9 studies, 3 showed an improvement. The dose that worked: 400 mg a day.
How much Indole-3-carbinol per day?
The studies taken by mouth that showed an improvement used 400 mg a day.
Can I take Indole-3-carbinol with my meds?
Some supplements can change how meds work or are absorbed. Members have every product checked against the meds in their Health Profile before it joins their protocol.
Educational, not medical advice. Figures come from the human studies on PubMed we have graded; a study counts for a form when it names the form it used. Updated as new studies arrive. How we grade →
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