Arms Race Nutrition Clarity Very Cherry Berry Review

Clarity Very Cherry Berry by Arms Race Nutrition is a supplement in powder form with 14 active ingredients, presented on this page as a product for focus, alertness, and brain function. The label directions say to mix 1 scoop with 8 to 12 ounces of water and consume daily during activities that require increased focus and alertness. The label lists a serving size of 9.2 g with 20 servings per container, and a net content of 6.4 ounces (184 g). The maker's own words describe it as a formulation combining research studies with trademarked ingredients, offering heightened focus and alertness while contributing to improved brain function, with the claims presented as the maker's words and not evaluated by the Food and Drug Administration. The listed active ingredients include Vitamin B6 at 100 mg, Vitamin B9 at 400 mcg, Vitamin B12 at 100 mcg, nooLVL at 1600 mg, Acetyl-L-Carnitine Hydrochloride at 1000 mg, L-Tyrosine at 1000 mg, Alpha-Glycerylphosphorylcholine at 600 mg, Mucuna pruriens Seed Extract at 500 mg, EnXtra at 300 mg, Bacopa monnieri Extract at 300 mg, Sabroxy at 100 mg, Caffeine Anhydrous at 100 mg, Caffeine at 50 mg, and Huperzia serrata Leaf and Stem Extract at 20 mg. Other ingredients listed are malic acid, natural and artificial flavors, citric acid, silicon dioxide, sucralose, and acesulfame potassium. The page reports that 10 of the 14 active ingredients matched its records, and that 1,406 drugs have a documented interaction with the supplement, with the most serious rated major. Ingredient transparency is rated full because the label gives an exact amount for each active ingredient. The label is dated June 2024 and was entered into the NIH Dietary Supplement Label Database on June 20, 2024. The page notes the product is on the market and is intended for adults aged 18 to 50 and women who are not pregnant or lactating. The page states that none of the ingredient names point to a major food allergen and that the label text carries no allergen statement. The page advises that the label on the bottle should always be read, and that the information is educational and not medical advice.

Product Focus: Focus and MemoryAlso covers:BrainDigestion
Tier ⓘ
Tier 4 · Rank 12
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 12 within Tier 4 for Focus and Memory; 34 of 49 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
35 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Biohacker Mentions
10 of 10

Study, Trial or Testing Result Summary

Members Only318 human studies · 168 improved

11 of these 318 human studies gave the ingredient by drip or injection, not by mouth.

318 human studies168 improved82 no effect1,443,713 people studied

Several main ingredients are at doses that worked in studies. nooLVL at 1600 milligrams improved memory reaction times and steadied accuracy and planning in small trials of gamers [1][2]. Alpha glycerylphosphorylcholine improved thinking in pooled trials of adults with memory problems [3] and in Alzheimer dementia [4]. Bacopa at 300 milligrams improved memory in older adults [5], though one trial at that dose found no benefit [6]. Caffeine improved attention in pooled trials [7]. Huperzine, from Huperzia serrata, improved memory in mostly low quality trials [8], with one trial finding no lasting benefit [9]. At two servings, tyrosine helped working memory under stress [10], and acetyl carnitine helped people with mild memory decline [11]. Sabroxy is far below the 1000 milligrams that helped memory in its one trial [12]. Velvet bean has only animal studies [13], and EnXtra has no studies given. Vitamins B6, folate and B12 did not improve thinking in people without deficiency [14]. Animal and cell studies are never counted.

See all 318 studies →Hide the studies

Review Totals and Summary

Members OnlyWhat buyers say

Written customer feedback on Clarity is sparse, and most of it comes from retailer listings such as NutriCartel, whose international customers include buyers in the UAE. The reviews I found are short and positive. Customers mention a noticeable lift in focus and mood, and one described the experience as "great focus, great feeling." Another reviewer on the same page praised "very nice mood elevation and focus." That matches the product's positioning as a mood-supportive, energized nootropic rather than a purely stimulant-based focus aid. Reviewers also praised the flavor, though the one flavor comment I found was about Lemon Rush rather than Very Cherry Berry, so I have no direct customer verdict on the cherry flavor. Retailer service and shipping drew compliments too, but that is feedback on the store, not the product. The positive themes are focus, a good feeling or mood boost, and an acceptable-tasting powder. I did not find substantial complaints, but that probably reflects how few reviews exist rather than a lack of problems. The review sample is tiny, with roughly three reviews on the main page I read. Large retailers and community forums gave me no usable detail on side effects, crashes, sleep disruption or jitters. Because the formula has 137.5 mg of caffeine plus tyrosine, some users may well react that way, but I cannot attribute those complaints to customers from what I found. Availability is a practical issue: the NutriCartel listing showed Very Cherry Berry as sold out at the time I looked, and the product is sold in a 20-serving size only. Professional write-ups from PricePlow and Stack3d were also favorable. They emphasized the clinically dosed ingredient list, the dual-release caffeine and the shift from the older capsule version. They are product-launch coverage, not user experience, so they do not show whether customers feel the effects over time. Overall, the available feedback suggests users like the mood and focus effect and the flavor, but there is not enough review volume to draw firm conclusions about taste, tolerability or long-term results.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

Alpha-GPC, the main ingredient, gets a mixed but mostly favorable read from the panel: two of them recommend it, one uses it, and three are neutral on it, with the rest not speaking about it as a main focus. People take it for focus, faster thinking and brain function, and one recommends it to boost growth hormone naturally. Doses named were 300 to 600 mg for focus, with up to 1,000 mg a day mentioned as an upper limit, and one person uses it in the morning with other brain supplements while another pairs it with caffeine, MCT and theanine in coffee for long stretches of mental work. One panelist prefers a different form of choline over Alpha-GPC, so it is not a universal favorite. Caffeine is a smaller ingredient in this product, and the panel's main advice on it is to keep it early in the day, with some people stopping it entirely.

See all 10 biohackers →Hide the biohackers
  • Andrew Huberman · Alpha-GPC · neutral
    • 22 Oct 2026 · neutral · Podcast ↗
      Discusses Alpha-GPC as a neuromodulator for cognitive enhancement and focus.
    • 26 Oct 2026 · Caffeine · uses · YouTube ↗
      Used caffeine, taking 400 milligrams, to improve his mood and physical vigor during mundane tasks like swimming, noting that it made life not so bad and allowed him to rip through the water.
    • 26 Oct 2026 · Caffeine · neutral · Podcast ↗
      Mentions caffeine in a discussion about supplement use.
    • 22 Oct 2026 · recommends · YouTube ↗
      He recommends alpha-GPC, a choline donor, at dosages of 300 to 600 mg, to enhance focus for mental or physical work by augmenting acetylcholine pathways, noting its half-life is about 4 to 6 hours.
    • 22 Oct 2026 · Caffeine · neutral · Podcast ↗
      Discusses caffeine timing as a tool related to sleep.
    • 22 Oct 2026 · Caffeine · warns · YouTube ↗
      He recommends caffeine, in coffee or tea form, or in tablet or capsule form at lower dosages than found in coffee and tea, as a reasonable way to explore stimulant-based approaches for enhancing cognitive function and focus.
    • 1 Oct 2026 · uses · YouTube ↗
      Uses Alpha-GPC at dosages of 300 to 600 milligrams prior to workouts or cognitive work, about four days a week, to increase focus and concentration, and takes garlic with it to offset potential TMAO increases.
    • 1 Oct 2026 · neutral · Podcast ↗
      Discusses Alpha-GPC, its relation to acetylcholine, and safety considerations.
    • 1 Oct 2026 · Caffeine · recommends · YouTube ↗
      Huberman states that caffeine can improve focus and concentration, with a general useful range of 100 to 400 milligrams, and most people do well with 100 to 200 milligrams prior to focused work.
    • 1 Oct 2026 · Caffeine · neutral · Podcast ↗
      Discusses caffeine as a tool for improving attention, noting its impact on focus and sleep.
    • 28 Sep 2026 · Caffeine · uses · YouTube ↗
      Mentions that coffee and tea produce caffeine, which were likely defense chemicals, and that plants learned it was better to alter consciousness than kill predators outright.
    • 28 Sep 2026 · Caffeine · uses · Podcast ↗
      Discusses caffeine and its health benefits.
    • 6 Aug 2026 · neutral · Podcast ↗
      Discusses Alpha-GPC as a supplement that can enhance acetylcholine.
    • 6 Aug 2026 · uses · YouTube ↗
      Uses Alpha-GPC, taking 300 mg prior to workouts or cognitive work bouts, three or four times per week in the early part of the day, to sharpen his focus and increase acetylcholine.
  • Dave Asprey · Alpha-GPC · neutral
    • 25 Apr 2026 · neutral · YouTube ↗
      Some people like Alpha-GPC for faster thinking, which is similar to CDP-choline, but Dave Asprey prefers CDP-choline.
    • 31 Oct 2026 · Caffeine · uses · YouTube ↗
      Loves coffee, has the caffeine molecule tattooed on his arm, drinks it every morning, and says it does amazing things for your brain and for how long you can live, but it can't clear most brain fog on its own.
    • 23 Oct 2026 · Caffeine · recommends · Instagram ↗
      Created Danger Coffee, a mineral-enriched, lab-tested, mold-free coffee that delivers rich flavor and clean caffeine without all the junk, and recommends it to others.
    • 22 Oct 2026 · Caffeine · recommends · YouTube ↗
      Dave Asprey's lab proved that caffeine is a flow hack and the only known substance to actually make you flow prone. Coffee will make you more flow prone.
    • 17 Oct 2026 · Folate · neutral · Facebook ↗
      States that folate can affect how the body responds to a supplement.
    • 11 Oct 2026 · Caffeine · recommends · Podcast ↗
      Dave explains why the 1:2 ratio of caffeine to L-theanine beats coffee alone for working memory, accuracy, and calm, sustained concentration.
    • 3 Oct 2026 · Caffeine · uses · YouTube ↗
      States that his entire career started on caffeine and he uses it every morning, but notes it's like a loan from your future self, leading to an afternoon crash.
    • 1 Oct 2026 · Caffeine · stopped · YouTube ↗
      Dave Asprey's company used caffeine, which is a safe ingredient, but they stopped using it because it doesn't provide the type of results and change in the skin that newer ingredients do.
    • 3 Sep 2026 · Caffeine · uses · YouTube ↗
      States that caffeine is one of his superpowers and increases the rate of ketone formation, which fuels neurons.
    • 31 Aug 2026 · Caffeine · uses · Instagram ↗
      Once I’ve hydrated and taken my creatine, I reach for Danger Coffee for caffeine and essential minerals in one cup.
    • 22 Aug 2026 · Caffeine · uses · YouTube ↗
      Uses caffeine, noting it blocks adenosine to increase norepinephrine and dopamine signaling, fueling the prefrontal cortex for focus. He mentions it got him through business school and is part of his longevity journey.
    • 13 Aug 2026 · Caffeine · warns · YouTube ↗
      Does not believe caffeine is a nootropic, considering it just a stimulant.
    • 5 Aug 2026 · Folate · recommends · Facebook ↗
      Recommends methylfolate as a better option than folic acid.
    • 1 Jul 2026 · Vitamin B12 · recommends · YouTube ↗
      States that Vitamin B12 is extremely important for every kind of brain function and recommends ensuring B12 levels are optimal, around 500, not just barely above normal.
  • Dr. Eric Berg · Alpha-GPC · recommends
    • 10 Oct 2025 · recommends · Podcast ↗
      Recommends Alpha-GPC to boost growth hormone naturally.
    • 19 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that birth control pills deplete the body of folate, which is needed for the brain to make serotonin.
    • 10 Oct 2026 · Vitamin B6 · warns · Podcast ↗
      Dr. Berg lists pyridoxine hydrochloride as a synthetic vitamin to avoid.
    • 4 Oct 2026 · Vitamin B6 · recommends · Facebook ↗
      Recommends taking the active form of vitamin B6, pyridoxal-5-phosphate (P5P), for its benefits to the nervous system, including building the myelin sheath and protecting sensory nerve integrity.
    • 4 Oct 2026 · Vitamin B6 · neutral · X ↗
      Notes that Vitamin B6 is intimately involved in the nervous system and may be behind sciatica and carpal tunnel syndrome.
    • 4 Oct 2026 · Vitamin B12 · recommends · Facebook ↗
      Recommends taking the natural form of vitamin B12, methylcobalamin, to support nerve regeneration, myelin production, and nerve growth factors.
    • 4 Oct 2026 · Vitamin B12 · neutral · X ↗
      Notes that Vitamin B12 is intimately involved in the nervous system and may be behind sciatica and carpal tunnel syndrome.
    • 25 Sep 2026 · Caffeine · warns · Podcast ↗
      Warns that caffeine can keep you awake and advises to watch out for hidden sources of caffeine.
    • 20 Sep 2026 · Vitamin B12 · recommends · Facebook ↗
      Recommends taking vitamin B12 if on a med.
    • 15 Sep 2026 · Vitamin B6 · neutral · Podcast ↗
      States that high vitamin B6 levels can be linked to peripheral neuropathy.
    • 15 Sep 2026 · Vitamin B12 · neutral · Podcast ↗
      Briefly mentions Vitamin B12 in relation to neuropathy.
    • 14 Sep 2026 · Caffeine · warns · Facebook ↗
      Stimulating the body with caffeine can actually make fatigue worse.
    • 10 Sep 2026 · Vitamin B12 · neutral · Instagram ↗
      States that vertical ridges on nails could mean a vitamin B12 deficiency, and slightly brown or grey nails, especially for vegans, could indicate low B12. Completely white nails with a pink strip across the top could also be low B12.
    • 8 Sep 2026 · Vitamin B12 · recommends · Instagram ↗
      Recommends incorporating vitamin B12 foods into the diet, especially for those who don't regularly consume animal products, to prevent irreversible damage to the nervous system.
  • Ben Greenfield · Alpha-GPC · uses
    • 1 Apr 2023 · uses · YouTube ↗
      Uses Alpha-GPC in the morning as part of a stack to push dopamine and acetylcholine for optimal brain function.
    • 24 Oct 2026 · Caffeine · stopped · Facebook ↗
      Came off caffeine for a year after his separation.
    • 24 Oct 2026 · Caffeine · stopped · Podcast ↗
      Quit caffeine in the same year he quit testosterone replacement therapy and alcohol.
    • 22 Oct 2026 · Caffeine · uses · YouTube ↗
      Uses caffeine, such as coffee or green tea, in his morning fasted fat-burning session to slightly increase the oxidation of fats.
    • 17 Oct 2026 · Caffeine · warns · YouTube ↗
      Advises against relying on caffeine for morning energy, suggesting that natural sugar-based stimulants combined with hydration and meditation can provide sufficient wakefulness.
    • 12 Oct 2026 · Folate · recommends · Facebook ↗
      Recommends methylfolate as an active form of folate that the body can use directly without conversion.
    • 27 Sep 2026 · Caffeine · recommends · Facebook ↗
      Recommends Caffeine, noting that it can improve focus, mood, and training, help control appetite, raise calories burned, and reduce fatigue.
    • 19 Sep 2026 · L-Carnitine · recommends · YouTube ↗
      Recommends L-carnitine for male fertility, explaining that it helps shuttle fatty acids into mitochondria, assisting with beta-oxidation, and its concentration in sperm correlates with sperm motility.
    • 19 Sep 2026 · L-Carnitine · neutral · Podcast ↗
      He mentions L-carnitine as a supplement with real human data behind it for male fertility.
    • 18 Sep 2026 · Caffeine · neutral · X ↗
      Notes that 3 mg/kg of caffeine increases fat oxidation by 31%, and 5 mg/kg increases it by 51% compared to a placebo.
    • 16 Sep 2026 · Caffeine · neutral · X ↗
      Caffeine on its own isn’t particularly impressive as an ergogenic aid, but when combined with taurine, there are significant increases in power production.
    • 14 Sep 2026 · Caffeine · neutral · X ↗
      Mentions that caffeine can help mitigate the negative effects of a caloric deficit on lean muscle mass and metabolism.
    • 11 Sep 2026 · Caffeine · neutral · X ↗
      Has talked before about caffeine as a supplement that seems to assist with sleep deprivation.
    • 8 Sep 2026 · L-Carnitine · recommends · X ↗
      Recommends L-carnitine at 1-3 grams per day for at least 30 days pre-conception to improve mitochondrial function tied to sperm quality.
  • Dr. Rhonda Patrick · Alpha-GPC · neutral
    • Date not recorded · neutral · Website ↗
      Notes that doses of alpha-GPC up to 1,000 milligrams a day have been observed as an upper limit.
    • 26 Oct 2026 · Caffeine · neutral · Instagram ↗
      Explains that caffeine can activate AMPK, a cellular energy sensor involved in fat burning and glucose regulation, which helps muscle cells take up glucose and promotes using fatty acids for energy.
    • 2 Oct 2026 · Caffeine · recommends · YouTube ↗
      Recommends pairing caffeine with L-theanine to enhance alertness and focus while mitigating anxiety and jitteriness, suggesting a dose of 100 to 150 mg of caffeine.
    • 30 Sep 2026 · Caffeine · recommends · Facebook ↗
      Recommends pairing coffee with L-theanine to enhance cognitive performance, noting that L-theanine can help balance caffeine’s stimulatory effects.
    • 28 Sep 2026 · Caffeine · warns · YouTube ↗
      Recommends cutting out caffeine in the three months before conception for both men and women, as it affects sperm.
    • 28 Sep 2026 · Folate · recommends · YouTube ↗
      Recommends ensuring adequate methyl folate intake, ideally through a prenatal vitamin, for women preparing for IVF.
    • 7 Sep 2026 · L-Carnitine · neutral · YouTube ↗
      Discusses L-carnitine's role as a transporter for fatty acids into mitochondria for energy, its role in detoxifying metabolites, and its involvement in stabilizing cell membranes and ketone production. They mention studies showing it helps increase muscle mass and improve cognitive function in women, and meta-analyses showing reductions in body weight, waist size, and body fat in overweight and obese individuals.
    • 14 Aug 2026 · Caffeine · recommends · Facebook ↗
      Recommends caffeine for alertness and focus, especially when combined with L-theanine to smooth out the response and maintain cognitive benefits, suggesting a practical dose of 100-150 mg.
    • 5 Jun 2026 · Caffeine · recommends · Instagram ↗
      Recommends cutting down or eliminating caffeine when actively trying to conceive.
    • 27 May 2026 · Caffeine · warns · Facebook ↗
      Warns that a very high dose of caffeine, around 350 mg pre-workout, may blunt some of creatine's performance benefit due to opposite effects on muscle relaxation.
    • 24 Mar 2026 · Caffeine · uses · YouTube ↗
      Self-administers 350 mg of caffeine in a bolus right after returning from mass and his workout, and before eating, noting that he likes dark roast Starbucks.
    • 6 Feb 2026 · Caffeine · neutral · Instagram ↗
      The newest literature on Caffeine dose and its link to multiple cardiometabolic disease risk reduction shows that even the ≥400 mg group was healthier than 0 mg.
    • 8 Oct 2025 · Caffeine · neutral · X ↗
      Explains that caffeine works by blocking adenosine, a molecule that builds up and makes one feel tired, and that timing coffee intake is about leveraging adenosine biology for peak cognitive alertness.
    • 8 Oct 2025 · Vitamin B12 · warns · Facebook ↗
      Warns that Vitamin B12 enhances light's melatonin-suppressing effects and should be avoided too close to bedtime.
  • Thomas DeLauer · Caffeine · neutral
    • 29 Oct 2026 · neutral · YouTube ↗
      Explains that caffeine from green tea mobilizes fatty acids, which can be converted into ketones, providing a ketone boost, especially in a fasted or low-carb state.
    • 27 Oct 2026 · warns · YouTube ↗
      Warns that treating brain fog with caffeine without addressing underlying inflammation is ineffective and likely to make the situation worse.
    • 21 Oct 2026 · uses · Facebook ↗
      Notes that caffeine significantly increased fat metabolism and fat oxidation during exercise, especially at lower intensities, and that adding coffee around an exercise bout led to more calories and fat burned.
    • 21 Oct 2026 · uses · Instagram ↗
      Says that caffeine significantly increased fat metabolism and that at low intensity cardio or exercise caffeine works better at mobilizing and utilizing fat.
    • 18 Oct 2026 · Vitamin B12 · recommends · YouTube ↗
      Recommends Vitamin B12 for mental health and mood, explaining its role in myelination and neurotransmitter production. They specifically recommend a liposomal and micellar form of methylcobalamin B12 for better absorption and to avoid toxicity.
    • 14 Oct 2026 · uses · YouTube ↗
      Might have some caffeine before fasted training.
    • 26 Sep 2026 · recommends · YouTube ↗
      Recommends caffeine as a must on the fasting day to create a low-grade energy demand that forces the body to favor lipolysis.
    • 2 Sep 2026 · recommends · YouTube ↗
      Recommends drinking 150 to 200 mg of caffeine immediately before a 20-minute nap to enhance alertness and performance, as the caffeine peaks when the nap has cleared adenosine.
    • 1 Sep 2026 · recommends · Instagram ↗
      States that caffeine is probably the most studied ergogenic aid with a profound effect on fat mobilization, suggesting that simple is better.
    • 25 Aug 2026 · neutral · YouTube ↗
      Mentions that people try cutting out caffeine when dealing with sleep issues, but it's not always the root cause.
    • 15 Aug 2026 · warns · YouTube ↗
      Warns that consuming more than 50-60 mg of caffeine in the first hour after waking stacks a stimulant on top of the body's natural cortisol-driven alertness, leading to a sharp spike and mid-morning crash, and building tolerance faster.
    • 30 Jun 2026 · Vitamin B12 · neutral · YouTube ↗
      Mentions that a single serving of sardines provides vitamin B12 at something like three to four times the daily needs.
    • 29 Jun 2026 · Vitamin B12 · recommends · YouTube ↗
      Recommends taking methylcobalamin as a methylated form of B vitamin for mitochondrial function.
    • 29 Jun 2026 · Folate · recommends · YouTube ↗
      Recommends taking methylfolate as a methylated form of B vitamin for mitochondrial function.
  • Siim Land · Caffeine · recommends
    • 25 Oct 2026 · recommends · Instagram ↗
      Recommends stopping caffeine earlier to improve sleep.
    • 19 Oct 2026 · neutral · YouTube ↗
      Notes that polyphenolic compounds in coffee, both decaf and regular caffeinated, can influence cellular stress pathways and have been seen to increase autophagy activity in mice, with regular coffee appearing more potent due to caffeine's additional energetic stress.
    • 12 Oct 2026 · recommends · Instagram ↗
      Recommends moving caffeine intake earlier in the day because having it too late can disrupt sleep, especially for slow metabolizers.
    • 12 Oct 2026 · warns · YouTube ↗
      Recommends not having caffeine after lunch, noting that 400 mg 4 hours before bed reduced deep sleep by approximately 30 minutes in a trial, although he personally has a fast caffeine metabolism.
    • 28 Sep 2026 · warns · YouTube ↗
      Warns that combining a large dose of glycine with caffeine can amplify negative experiences, as caffeine independently increases arousal and can cause restlessness, anxiety, and increased heart rate.
    • 25 Sep 2026 · recommends · YouTube ↗
      States that regular coffee promotes visceral fat loss, and going from low or zero intake to moderate intake increases fat loss due to caffeine and polyphenols.
    • 15 Jun 2026 · recommends · YouTube ↗
      Suggests that higher caffeine intake might be useful for older people because caffeine raises cortisol, and consuming it in the morning contributes to circadian regulation.
    • 12 Jun 2026 · recommends · YouTube ↗
      States that caffeine has proven benefits for increasing exercise performance when used correctly and at the right time.
    • 7 Jun 2026 · neutral · X ↗
      States that caffeine raises blood pressure, but mostly if one is not used to consuming it, and habitual caffeine consumers develop tolerance to these effects.
    • 6 Jun 2026 · neutral · X ↗
      Quotes a tweet suggesting that without caffeine, civilization would be 100 years behind.
    • 24 Apr 2026 · Vitamin B12 · uses · YouTube ↗
      Created Microvitamin, a supplement that bundled all the supplements he was taking, to help fund his a med trial.
    • 24 Mar 2026 · Vitamin B12 · recommends · YouTube ↗
      States that vitamin B12 deficiency is the most common reason for premature graying of hair and recommends fixing B12 status if it is deficient, as it gives a greater likelihood of reversing gray hair.
    • 17 Jan 2026 · Folate · neutral · Instagram ↗
      States that Homocysteine levels can often be improved through adequate folate intake.
    • 23 Aug 2025 · Folate · warns · YouTube ↗
      Notes that Brian's folate levels are over 20, which is too high and above the reference range, possibly due to supplementation.
  • Dr. Mark Hyman · Folate · neutral
    • 21 Oct 2026 · neutral · YouTube ↗
      Notes that taking folate can lower homocysteine levels, which has shown health benefits and physical improvements in brain scans in clinical trials.
    • 19 Oct 2026 · neutral · YouTube ↗
      Notes that some people may need a little bit extra folate with a supplement.
    • 7 Oct 2026 · Caffeine · warns · YouTube ↗
      Discusses with patients their caffeine consumption, suggesting that too much caffeine can artificially increase their stress response.
    • 17 Sep 2026 · Caffeine · recommends · X ↗
      Recommends stopping caffeine by noon.
    • 31 Aug 2026 · uses · YouTube ↗
      Optimized a child's nutrient status with folate, as the child had low folate levels and was not eating greens.
    • 31 Aug 2026 · Caffeine · neutral · YouTube ↗
      States that caffeine's effect on ADHD depends on the person, as it can help focus but also activate irritation or stress, and its impact is related to individual caffeine metabolism.
    • 31 Aug 2026 · Vitamin B6 · uses · YouTube ↗
      Optimized a child's nutrient status with vitamin B6, as the child had low B6 levels.
    • 28 Jul 2026 · neutral · Facebook ↗
      Notes that a med depletes folate.
    • 22 Jul 2026 · recommends · YouTube ↗
      States that folate is a nutritional deficiency that impacts mental health.
    • 22 Jul 2026 · Vitamin B12 · recommends · YouTube ↗
      States that vitamin B12 is a nutritional deficiency that impacts mental health.
    • 20 Jul 2026 · Caffeine · warns · YouTube ↗
      Warns that drinking coffee first thing in the morning before eating layers caffeine on top of already elevated stress hormones, providing unsustainable energy and setting up for an afternoon crash.
    • 8 Jul 2026 · uses · YouTube ↗
      Recounts giving a patient with MCI high-dose methylfolate, along with B12 shots and B6, which completely cured her MCI.
    • 29 Jun 2026 · recommends · Facebook ↗
      Recommends folate with vitamin B6 and B12 as supplements with strong evidence for PMS.
    • 29 Jun 2026 · Caffeine · neutral · Facebook ↗
      Notes that caffeine is one of the things that drives the hormone imbalance causing PMS.
  • Bryan Johnson · Caffeine · uses
    • 23 Sep 2026 · uses · YouTube ↗
      Drinks coffee when starting to fade, ensuring the last cup is between 10 and 12 hours before bed so caffeine doesn't affect sleep.
    • 18 Jun 2026 · uses · X ↗
      Used 300 mg of caffeine in the morning as part of their jet lag recovery.
    • 7 Jun 2026 · uses · X ↗
      Uses 300 mg of slow release caffeine in the morning as part of a jet lag recovery protocol.
    • 25 Apr 2026 · neutral · X ↗
      Notes that coffee affects the gut, which then affects the brain, and that it is the coffee bean, not the caffeine, doing most of the work.
    • 19 Nov 2025 · warns · YouTube ↗
      Notes that the culture in DC involves running on caffeine, along with alcohol and sleep deprivation, leading to poor nutrition and an unhealthy environment.
    • 3 Jul 2025 · warns · YouTube ↗
      Warns that caffeine has a 6-hour half-life, so consuming it later in the day will leave a significant amount in the body at bedtime, recommending consumption earlier in the day.
    • 5 Jun 2025 · Vitamin B12 · uses · YouTube ↗
      States that Blueprint essential capsules and soft gels are packed with key vitamins and minerals needed for strong bone health.
    • 12 Apr 2025 · recommends · YouTube ↗
      Recommends consuming no caffeine past noon due to its 6-hour half-life, suggesting that if sleep is nailed, caffeine might not be needed.
    • 6 Nov 2024 · warns · YouTube ↗
      Warns against stimulants like caffeine for sleep, advising to have the last cup of coffee before noon if going to bed at 10:00 p.m.
    • 16 Oct 2024 · stopped · YouTube ↗
      Advises that if one is going to drink caffeine, they should try to have it earlier in the day and experiment to find the right time that doesn't disrupt their sleep.
    • 23 Mar 2024 · stopped · YouTube ↗
      Has stopped all caffeine, as it has helped him improve his sleep.
    • Date not recorded · Folate · recommends · Source ↗
      Recommends supplementing with folate for brain health for both the mother and the baby during pregnancy.
  • Peter Attia · Caffeine · uses
    • 16 Aug 2026 · uses · YouTube ↗
      States that he needs two to three times the normal dose of any medication or drug to feel an effect, including caffeine, and can drink four cups of coffee without feeling anything.
    • 4 Jan 2026 · neutral · YouTube ↗
      Mentions data suggesting caffeine might be more helpful in the luteal phase to help with fatigue components.
    • 12 Dec 2025 · uses · YouTube ↗
      Uses caffeine in combination with Alpha GPC, MCT, and Theanine, often adding it to coffee for long periods of cognitive work.
    • 7 Dec 2025 · uses · YouTube ↗
      Finds Alpha GPC works well with caffeine, and he puts a product containing Alpha GPC, MCT, and caffeine into his coffee for long periods of cognitive work.
    • 4 May 2025 · neutral · YouTube ↗
      Mentions that experimenting with the timing of caffeine is a great idea for sleep.
    • 27 Mar 2025 · warns · YouTube ↗
      Warns that decaffeinated coffee can contain significant amounts of caffeine and advises cutting off all coffee, including decaf, by 11 a.m. for better sleep quality.
    • 23 Mar 2025 · warns · YouTube ↗
      Explains that caffeine is problematic because it blocks adenosine receptors, leading to a 'caffeine crash' when it wears off and adenosine floods the receptors, causing sleepiness.
    • 10 Dec 2024 · neutral · YouTube ↗
      States that caffeine does not wake him up, which contributed to his belief that he did not have an addiction gene.
    • 14 Oct 2024 · neutral · YouTube ↗
      States that caffeine does not wake him up.
    • 10 Oct 2024 · warns · YouTube ↗
      Warns that constantly consuming caffeine and Red Bull to turn up the sympathetic dial is a sign that the sympathetic system isn't working as it should, possibly due to overstimulation from stress.
    • 9 Sep 2024 · Vitamin B12 · neutral · YouTube ↗
      Notes that deficiencies in certain vitamins and minerals, such as B12, can be a cause of hair loss in women.
    • 19 Aug 2024 · Folate · recommends · YouTube ↗
      Highlights folate supplementation as a significant practical progress in nutrition science, which has radically reduced spinabifida.
    • 3 Mar 2024 · L-Carnitine · warns · YouTube ↗
      Discusses L-carnitine, noting that people inject it for fat loss and to get more out of testosterone input, but warns against injecting it due to potential contamination from homebrewing or even compounding pharmacies, which have had issues leading to deaths.
    • 26 Feb 2024 · L-Carnitine · warns · YouTube ↗
      Warns that injecting L-carnitine, especially if home-brewed, is a bad idea due to sterilization concerns and potential for contamination, which can lead to serious health issues.

RAL Summary

Members OnlyTier 4 for Focus and Memory

Studies support several full-dose ingredients such as alpha glycerylphosphorylcholine [3], but only 10 reviews were counted with half positive, too few for a higher tier, so the evidence stays mixed at tier 4.

Take 2 servings a day to match the dose that worked in the studies.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 82 of the 318 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Nervous system, Digestive system

Combine with: For its intended cognitive purpose, Clarity pairs well with Alpha-GPC or CDP-choline for acetylcholine support, Bacopa monnieri or Lion's Mane for longer-term memory and focus support, and omega-3 fish oil (DHA/EPA) for brain cell membrane health. Rhodiola rosea can help with mental fatigue, and magnesium L-threonate may support calm cognition. If you are prone to heartburn, take it with food, limit the dose, and consider a separate heartburn product such as calcium carbonate antacid, alginate (sodium alginate) raft-forming formula, or DGL licorice for digestive comfort, spaced apart from the stimulant. Stay hydrated and avoid taking it late in the day to protect sleep.

Possible side effects: Bacopa caused stomach upset such as cramps, nausea and loose stools in some trials, and higher tyrosine doses worsened working memory in older adults. With 150 milligrams of caffeine, jitters or sleep trouble are possible, but no reviews reported them.

Supplement Facts

Vitamin B6 100 mg · Vitamin B9 400 mcg · Vitamin B12 100 mcg
Supplement Facts
Serving Size 9.2 Gram(s)
Servings Per Container 20
Amount Per Serving% Daily Value
Vitamin B6100 mg
Vitamin B9400 mcg
Vitamin B12100 mcg
nooLVL1,600 mg†
Acetyl-L-Carnitine Hydrochloride1,000 mg†
L-Tyrosine1,000 mg†
Alpha-Glycerylphosphorylcholine600 mg†
Mucuna pruriens Seed Extract500 mg†
EnXtra300 mg†
Bacopa monnieri Extract300 mg†
Sabroxy100 mg†
Caffeine Anhydrous100 mg†
Caffeine50 mg†
Huperzia serrata Leaf, Stem Extract20 mg†
† Daily Value not established.

Other ingredients: Malic Acid, Natural & Artificial Flavors, Citric Acid, Silicon Dioxide, Sucralose, Acesulfame Potassium.

Directions: Directions: Mix 1 scoop with 8-12 ounces of water and consume daily during activities that require increased focus and alertness.

Barcode (UPC) 658580432829 · Label source: NIH label database · Report a label change

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Our articles on this subject

Graded November 8, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.