Formutech Nutrition Carve Water Loss Review
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Study, Trial or Testing Result Summary
Members Only42 human studies · 30 improved
This is a water loss formula, and none of its ingredients has been tested in people for fast heartburn relief in this form. Magnesium is at a full dose, but its support comes mostly from antacid mixtures, often with aluminium. Those mixtures gave complete heartburn relief more often than placebo in pregnant women [1], helped 88% of pregnant women within two weeks [2], and raised stomach pH within about 6 minutes [3]. One trial found no benefit over placebo [4]. Green tea extract, at slightly below the studied 500 milligrams, eased indigestion symptoms over 8 weeks [5], but green tea drinkers were more likely to have reflux in another study [6]. Vitamin B6 studies disagree: one linked higher intake to less reflux [7] and another to more [8]. Potassium did not change reflux or acidity [9]. Dandelion was helpful only as part of a herb blend in a study without placebo [10]. Evodia fruit and resveratrol have only animal studies [11][12]. Uva ursi has no human studies for this goal. Animal and cell studies are never counted.
See all 42 studies →Hide the studies
- In a review of nine small trials in pregnant women, drug treatments including a magnesium-aluminium antacid with simethicone gave complete heartburn relief more often than placebo or no treatment, though evidence was limited.Interventions for heartburn in pregnancy.
- A review of nutrition trials in children with cerebral palsy found magnesium helped constipation but did not assess heartburn relief.Dietary and nutritional interventions in children with cerebral palsy: A systematic literature review.
- In 351 adults with acid reflux disease, a blend containing vitamin B6 plus melatonin and other nutrients led to complete symptom relief in all 176 people after 40 days, versus 65.7% of those taking a med, though the vitamin B6 effect cannot be separated from the other ingredients.Read the study on PubMed (16948779) →
- In 276 adults with indigestion, one month of a simethicone, charcoal and magnesium oxide combination lowered overall symptoms and epigastric burning more than placebo.Efficacy of a simethicone, activated charcoal and magnesium oxide combination (Carbosymag®) in functional dyspepsia: res…
- In 100 pregnant women with heartburn, a magnesium-aluminium antacid gel for two weeks worked about as well as an alginate-based product, with 88% improving in heartburn frequency versus 80%.Efficacy of alginate-based reflux suppressant and magnesium-aluminium antacid gel for treatment of heartburn in pregnanc…
- In 100 adults with functional dyspepsia, 500 mg a day of green tea seed and leaf extract for 8 weeks reduced overall digestive symptoms, including reflux and abdominal pain, more than placebo, with no treatment-related adverse events.Effects of a green tea seed and leaf extract complex on functional dyspepsia: A randomized, double-blind, placebo-contro…
- In 97 patients with gastritis, esophagitis or upper abdominal complaints, a magnesium and aluminium hydroxide antacid with smectite beat an aluminium hydroxide antacid on pain relief, speed of effect and heartburn over four weeks.[Antacid therapy of upper abdominal symptoms. Double-blind study on the effect and tolerance of 2 antacids in gastritis …
- In 90 people with acid reflux disease, adding magnesium-containing mineral water to standard treatment for a month improved indigestion and pain more than standard treatment alone.Application of mineral waters in the complex treatment of patients with gastroesophageal reflux disease.
- In 89 people with nonulcer indigestion, four weeks of an aluminum-magnesium antacid did not relieve symptoms compared with placebo.Antacids reduce Campylobacter pylori colonization without healing the gastritis in patients with nonulcer dyspepsia and …
- In 89 people with reflux not helped by standard drugs, a regimen including magnesium aluminum carbonate gave the best improvement in heartburn sensation compared with a herbal decoction.Efficacy evaluation and exploratory analysis of influencing factors of Banxia Houpu Decoction in the treatment of refrac…
- In 80 children with reflux, 8 weeks of domperidone plus magnesium and aluminum hydroxide fully cleared symptoms in 16 of 20 children, versus 7 of 20 on placebo.Domperidone plus magnesium hydroxide and aluminum hydroxide: a valid therapy in children with gastroesophageal reflux. A…
- In 72 infants with regurgitation, two weeks of magnesium alginate lowered reflux symptom scores about as well as thickened formula, at slightly lower cost.Magnesium Alginate in Gastro-Esophageal Reflux: A Randomized Multicenter Cross-Over Study in Infants.
- In 64 infants with reflux, magnesium alginate plus simethicone reduced symptom scores more than thickened formula or reassurance alone over up to 2 months.Effect of magnesium alginate plus simethicone on gastroesophageal reflux in infants.
- In 50 adults with throat reflux, 2 months of magnesium alginate suspension reduced symptoms and signs about as much as a med 20 mg daily.Read the study on PubMed (35032204) →
- In 49 adults with constipation-type irritable bowel syndrome, a drink with 2 mg vitamin B6, inulin and menthol taken for 2 weeks improved bowel symptoms but caused noticeable heartburn in 10 of 25 people who drank it.[Using a multicomponent functional food in IBS patients with constipation a comparative controlled study].
- In 44 people with reflux, 23 percent reported good relief on a magnesium-aluminium antacid gel over two 15-day periods, compared with 84 percent on Liquid Gaviscon.A comparative crossover study on the treatment of heartburn and epigastric pain: Liquid Gaviscon and a magnesium--alumin…
- In 37 people with chronic dyspepsia, an aluminium-magnesium antacid plus antispasmodic tablet relieved heartburn earlier and more than aluminium hydroxide alone over 4 weeks.A comparison of an antacid plus antispasmodic combination and aluminium hydroxide in dyspepsia.
- In 30 patients with stomach or duodenal ulcers, antacids containing 1.6 g magnesium hydroxide and 1.6 g aluminium hydroxide daily relieved heartburn and pain, but less than when triletide was added.Controlled clinical assessment of the efficacy and tolerance of triletide versus antacids in patients with gastric and d…
- In 24 healthy volunteers, a single dose of Riopan Gel (800 mg magaldrate) or Rennie tablets raised stomach pH for a short time compared with no drug, with Riopan acting faster in the first 5 minutes.Comparison of two antacid preparations on intragastric acidity--a two-centre open randomised cross-over placebo-controll…
- In 20 adults with chronic cough, the antacid Maalox reduced cough-like efforts triggered by deep lung emptying within minutes, while placebo did not, though this study measured cough rather than heartburn.Effect of an anti-reflux medical device in the control of deflation cough: A placebo-controlled comparative study with a…
- In 11 healthy volunteers and 9 people with chronic reflux, 4 days of potassium nitrate (dose not stated) did not change stomach acidity, acid reflux, or reflux symptoms compared with placebo, though it slightly improved how well the food pipe contracted.Effects of dietary nitrate on oesophageal motor function and gastro-oesophageal acid exposure in healthy volunteers and …
- In 16 healthy fasting adults, a single 1360 mg dose of the calcium-magnesium antacid Rennie raised stomach acid pH above 3 within about 6 minutes, compared with about 240 minutes with placebo.Comparison of the effect of the antacid Rennie versus low-dose H2-receptor antagonists (ranitidine, famotidine) on intra…
- In 15 patients with reflux-related eye symptoms, a month of magnesium alginate eye drops and tablets brought tear film measures back to normal values.Ocular Surface Disease as Extraesophageal Gastroesophageal Reflux Disease Manifestation: A Specific Therapeutic Strategy…
- In people with reflux oesophagitis over 10 weeks, Gastrocote reduced heartburn days from baseline, though acid exposure was no lower than with cimetidine and the combination with cimetidine worked best.Combined cimetidine-alginate antacid therapy versus single agent treatment for reflux oesophagitis: results of prospecti…
- A single 1.5 gram dose of the aluminium-magnesium antacid almagate was effective for reflux damage to the food pipe in a double-blind crossover trial, with both tested formulations performing equally.Effectiveness of almagate in gastroesophageal reflux disease: a post-hoc analysis of a randomized cross-over double-blin…
- In infants under one year with reflux, giving a small formula feeding before a standard magnesium-aluminum antacid dose improved how well the antacid buffered stomach acid.Antacid and formula effects on gastric acidity in infants with gastroesophageal reflux.
- In 169 people with heartburn, the aluminum-magnesium antacid almagate was effective, and most patients were symptom free by the end of a 2-week open trial with no control group.Treatment of gastric pyrosis with almagate in patients with and without endoscopically demonstrable duodenal ulcer. A mu…
- In 89 people with high blood pressure taking a combined pill with 600 mg potassium chloride for 9 months, heartburn was the second most common symptom reported, after headache. This study did not test heartburn as a treatment goal.Oxprenolol slow-release with cyclopenthiazide KCl in the treatment of essential hypertension. A multicentre general prac…
- In 61 adults with fatty liver disease and stomach or bowel symptoms, drinking 400 mL of a magnesium-containing mineral water daily for six months improved lower bowel symptoms, which worsened after stopping; the study had no placebo group and did not test heartburn directly.The use of bicarbonate-sulphate-calcium-magnesium and sodium-low drinkable water improves functional gastrointestinal sy…
- In 60 elderly patients with reflux, an alginate product (Geviskon) relieved heartburn, regurgitation, cough and sore throat more completely and faster than an aluminum-magnesium antacid over 7 days.[Using gaviscon preparation for relief of esophageal, extraesophageal syndromes and functional dyspepsia in elderly pati…
- In 49 healthy adults, a combined esomeprazole and magnesium hydroxide tablet raised stomach pH to 4 faster than enteric-coated esomeprazole alone over seven days of dosing.Pharmacokinetics and Pharmacodynamics of a Fixed-Dose Combination of Esomeprazole and Magnesium Hydroxide Compared to th…
- In a large cohort of about 356,000 people, harder tap water was linked to lower risk of some digestive conditions such as dyspepsia, but moderately hard water was linked to higher risk of reflux disease and peptic ulcer.Water hardness and digestive diseases: a large-scale population-based prospective cohort study.
- In a study of 11,690 people who had endoscopy and diet records, higher dietary vitamin B6 intake was linked to lower odds of non-erosive reflux disease, though this does not prove cause.Gender-specific Effect of Micronutrient on Non-erosive Reflux Disease and Erosive Esophagitis.
- In 2,853 Japanese adults in a health examination program, drinking green tea was linked to a higher likelihood of reflux disease, alongside high body weight, short sleep, and lack of exercise.Lifestyle change influences on GERD in Japan: a study of participants in a health examination program.
- In a case-control study of 150 women with reflux and 300 controls in Iran, higher dietary vitamin B6 intake was linked to higher odds of reflux disease.Dietary Vitamin B6 Intake and Gastroesophageal Reflux Disease: A Case-Control Study.
- In a cross-sectional study of 328 young adults, lower dietary vitamin B6 intake was linked to higher overall gastrointestinal symptom scores, but vitamin B6 intake was not directly linked to reflux status.Health cooking at home: can cooking skills reduce gastrointestinal symptoms, cross sectional study?
- In 305 outpatients with functional dyspepsia taking a multi-herb capsule that included dandelion root, 79% had at least a 50% drop in symptom scores after 60 days, though the study had no placebo group and dandelion's share could not be separated from the other herbs.[Phytotherapy with a mixture of dry extracts with hepato-protective effects containing artichoke leaves in the managemen…
- In 100 outpatients with throat reflux, two months of magnesium alginate significantly reduced voice problems, swallowing trouble and cough on a visual scale, with no side effects reported.Magnesium alginate in patients with laryngopharyngeal reflux.
- In 15 children with reflux treated with magnesium and aluminium hydroxide for eight weeks, 12 were cured and 3 improved, and acid reflux measured on pH monitoring was significantly reduced.[Magnesium hydroxide and aluminum hydroxide in the treatment of gastroesophageal reflux].
- Drinking a magnesium-rich sulphate mineral water was linked to fewer symptoms and better heart measures in people with mild gastroesophageal reflux and heart-related symptoms.[Magnesium-containing mineral waters in the treatment of patients with cardial manifestations of gastroesophageal reflux…
- In a lab and small test in normal people, acidic stomach contents helped an alginate and magnesium antacid mixture form a protective floating barrier against reflux, while plain water did not.Use of 111In-labeled alginate to study the pH dependence of alginic acid anti-esophageal reflux barrier.
- A 1994 Ukrainian report describes an antacid containing alginic acid and magnesium, used with antisecretory drugs for dyspepsia and reflux, that forms a protective floating layer in the stomach, but the abstract gives no patient numbers or outcome figures.[The use of 3rd-generation antacid preparations for the treatment of patients with nonulcerous dyspepsia and peptic ulce…
Review Totals and Summary
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Biohacker Summary
Members Only0 of 10 recommend it
All ten panelists spoke about magnesium, and most recommend or use it, with only one staying neutral. The main reason is sleep, along with muscle recovery, cramps, vitamin D function, blood pressure and bone support. Preferred forms are glycinate, which two or three praise for absorption and nightly use, and threonate, which three take at 400 mg before bed, while glycinate is also advised at around 300 to 400 mg a day from diet and supplements. Several pair it with electrolyte drinks that contain sodium and potassium, or with vitamin D and protein, and one suggests better forms because magnesium alone did not stop night waking for them. Nobody said they stopped, and potassium and green tea are smaller ingredients in this product that a few panelists also use or recommend.
See all 10 biohackers →Hide the biohackers
Dr. Rhonda Patrick · Magnesium · recommends
- Explains that magnesium helps the body activate and metabolize vitamin D, and that magnesium intake has been associated with lower odds of vitamin D deficiency and insufficiency.
- Mentions that getting too little magnesium may play a role in declining testosterone levels.
- Recommends getting enough magnesium, around 300–400 mg daily from diet and supplements, as it is an essential cofactor for vitamin D metabolism. Magnesium glycinate is a good form.
- Mentions magnesium as one of the micronutrients found in multivitamins that people often don't get enough of from their diets.
- Explains that magnesium helps control blood pressure by boosting the production of substances that relax blood vessels and improve cardiovascular health, citing a meta-analysis that found magnesium supplementation at an average dose of 368 mg per day notably lowers both systolic and diastolic blood pressure.
- Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
- Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
- Mentions magnesium as an important nutrient component for testosterone.
- Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
- States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
- Recommends getting enough potassium, noting that most people get too much sodium and not enough potassium.
- Rhonda takes 500 mg of Resveratrol daily for longevity.
- States that resveratrol was not only unhelpful but actually blocked some of the benefit of Nicotinamide Riboside in a peripheral artery disease trial, calling it 'science fiction'.
- Notes that while red wine contains beneficial compounds like resveratrol, the quantities are minimal, typically between 0.03 and 1 milligram per glass, which is starkly lower than the 50 to 500 milligrams used in lab studies showing health benefits.
Dr. Eric Berg · Magnesium · recommends
- Recommends Magnesium glycinate, noting its high absorption rate compared to magnesium oxide, and its support for energy, sleep, muscle relaxation, and vitamin D function.
- Dr. Berg states that when nutrients like magnesium are too low, fatigue and weakness can follow.
- Recommends potassium as an important electrolyte, noting that most people get less than half of the 4700 mg RDA.
- Recommends focusing on magnesium to support stronger bones if a neck hump is associated with osteoporosis.
- Explains that leg and calf cramps are most often caused by low magnesium, with leafy greens being a top source.
- States that magnesium is a cofactor that allows B1 to work more efficiently.
- States that magnesium is the most important mineral for energy production, as one cannot make energy without it.
- Magnesium is involved in 300 to 600 enzyme reactions, acts as a biological brake pedal, is the master controller over calcium, and is involved in making ATP, the energy currency of the body. It takes energy to go to sleep, and magnesium is required for relaxation and good sleep. Magnesium also helps balance cortisol levels and calm you.
- States that vitamin B6 is needed to absorb magnesium.
- Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
- States that people need more potassium than any other mineral, yet most people aren’t getting enough.
- Notes that magnesium could also be a factor in preventing muscle cramps.
- Explains that potassium is essential for peristalsis, the pumping action through the colon, and without it, things can sit there, leading to constipation.
- Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
Thomas DeLauer · Magnesium · recommends
- Recommends taking magnesium glycinate and threonate at night to act as a brake on the nervous system, block excitatory signaling, help wind down, and support serotonin and melatonin production for better sleep.
- Mentions that magnesium glycinate also helps a lot with sleep.
- Or, I'll just go to something much lower caffeine. Like, I'll sip on green tea. I put a link down below for Peak Matcha. So, Peak Tea is really good quality tea.
- Mentions that restless leg syndrome is often treated with magnesium, but states that the sensation is actually coming from three other issues.
- Recommends Element electrolytes, noting they are focused on sodium first, then potassium, then magnesium, helping with sending signals and hydrating tissue.
- Now rotates green tea with coffee, having green tea for two days, then coffee for two days, to maintain energy and benefit from different antioxidant profiles. He previously focused too much on green tea and neglected coffee.
- Combines MCT oil with matcha green tea in a cognitive cocktail, finding that green tea provides more mental benefits than coffee for focus and calm energy.
- Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
- Uses Element's cans which contain 100 milligram potassium, finding that electrolytes help his workout performance.
- Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
- Uses Element's 100 mg potassium cans first thing in the morning to prime his day and help with workout performance.
- Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
- Explains that green tea's catechin benefits often diminish in the intestines, with less than 20% surviving digestion, but adding citrus can reclaim these benefits by about 5x.
- Recommends adding citrus, specifically lemon, to green tea to reclaim the benefits of catechins, as it can leave 80% of them intact.
Andrew Huberman · Magnesium · recommends
- Notes that Les Spellman's team includes 'Magnesium timed right' as part of their game plan to optimize recovery in unfavorable conditions.
- Discusses Magnesium Threonate as a tool for falling asleep.
- Drinks green tea and believes it has very positive cognitive benefits in terms of focus.
- Takes 400 mg of Magnesium Threonate before bed for sleep.
- Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
- Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
- Takes 400 mg of Magnesium L-Threonate before bed for sleep.
- Confirms that magnesium is absolutely important for cognitive function, noting studies show those with lower magnesium intakes tend to perform less well on cognitive function tests, and it's related to brain changes over time and dementia risk.
- Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
- Uses Athletic Greens AG1 in the morning for gut health.
- He takes 400 mg of Magnesium L-Threonate from Double Wood before bed for sleep.
- Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of magnesium L-threonate before bed for sleep.
- Uses Element, which contains potassium in the correct ratios, to ensure proper hydration and electrolyte intake for brain and body function.
Dr. Mark Hyman · Magnesium · recommends
- Recommends magnesium breakthrough advanced ten from Biooptimizers, which is their most complete magnesium formula with 10 bioavailable forms and 550 milligrams of elemental magnesium, designed to support restful restorative sleep, muscle recovery, stress resilience, and metabolic health.
- Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
- Explains that a lack of magnesium can cause muscles and nerves to malfunction, resulting in muscle weakness, twitching, and cramps.
- Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
- Warns that potassium bromate, a dough conditioner banned in the EU, UK, and Canada, is still allowed in U.S. bread.
- Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
- Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
- Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
- Has recommended magnesium breakthrough from bioptimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
- Mentions that EGCG from green tea activates thermogenesis, contributing to calorie burning.
- Recommends correcting nutrient deficiencies with magnesium.
- Recommends Magnesium Breakthrough Advance 10 from BiOptimizers, which has 10 bioavailable forms of magnesium and more elemental magnesium, as part of his evening routine for sleep, muscle recovery, and metabolic health.
- Optimized a child's nutrient status with vitamin B6, as the child had low B6 levels.
- States that potassium plays a critical role in nerve signaling and muscle contraction, especially in the heart, and low levels can lead to dangerous irregular heart rhythms.
Dave Asprey · Magnesium · uses
- Looks at magnesium alongside protein to keep muscle for the long run.
- Suggests adding magnesium to help keep potassium in the system longer, as they work hand in hand.
- Explains that potassium helps open a gate, allowing creatine to slip through and cross the blood-brain barrier more effectively.
- Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
- Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
- States that magnesium can affect how the body responds to a supplement.
- Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
- Warns that very high doses of EGCG or green tea extract could cause harm to the liver.
- Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
- Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
- Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
- Recommends Vinia, stating that one capsule has the same piceid resveratrol as 1,000 red grapes, and it supports the activity of sirtuins and works as an antioxidant.
- Dave Asprey recommends Magnesium Glycinate for sleep, noting human studies show it helps people fall asleep faster, is safe, and works on a fundamental aspect of health, unlike magnesium oxide which acts as a laxative.
- Dave Asprey warns that resveratrol, despite launching the longevity supplement industry, has never delivered on its mouse data promises, with 20 years of inconsistent human trial results.
Ben Greenfield · Magnesium · uses
- Uses magnesium during surgery because it is neuroprotective.
- Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
- Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
- Mentions magnesium as part of a bare-minimum protocol.
- Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
- Mentions resveratrol as a known agent for mitochondrial biogenesis.
- Recommends supplementing with magnesium threonate if one is low in magnesium, as it crosses the blood-brain barrier and is demonstrated to increase hippocampus plasticity, theoretically making one smarter and improving memories.
- Uses Magnesium Breakthrough from BIOptimizers as part of their daily stack, taking four capsules in the evening to support relaxation, recovery, and a good night of sleep.
- Drinks green tea in the morning as part of her quiet time.
- Recommends Celtic Sea Salt's new electrolyte drink "Hydrate" for replacing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, plus magnesium, taurine, and potassium.
- Recommends Celtic Sea Salt's new electrolyte drink 'Hydrate' for replenishing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, magnesium, taurine, and potassium, with no added sugar, artificial colors, or synthetic ingredients.
- Had heart palpitations when he was really overdoing magnesium, not knowing what he was taking.
- Recommends taking magnesium as a co-factor to increase vitamin D absorption.
- Used to take dandelion root pre-show as a bodybuilder as a pretty potent a med to get a lot of fluids out of the body.
Siim Land · Magnesium · recommends
- States that Magnesium can be a useful addition for some people for sleep.
- States that green tea is very effective for visceral fat loss due to its polyphenol content.
- Personally drinks 2 cups of green tea a day and made it one of the small changes while reducing his visceral fat.
- Mentions that green tea's EGCG has stimulated autophagy in cultured liver cells and mouse experiments by increasing AMPK.
- Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
- Consumed more polyphenol-rich foods, including green tea, to reduce visceral fat.
- Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
- Lists Magnesium as one of 15 supplements backed by human studies.
- States that magnesium is a fundamental mineral governing over 600 enzymes and metabolic reactions, and recommends that most people need at least 400-500 mg/d for health, with some needing up to 600 mg/d.
- Lists seafood and pumpkin seeds as sources of Magnesium.
- Mentions that he drank green tea, which targets visceral fat, as one of the things he did to reduce visceral fat.
- Lists potatoes and fruit as sources of Potassium.
- Drinks 1-3 cups of green tea a day, noting that there are multiple lines of evidence suggesting it improves various health markers and may have longevity benefits.
- States that green tea is one of the healthiest beverages in the world, improving cardiovascular disease risk factors, heart health, metabolic health markers, targeting all hallmarks of aging, reducing visceral fat, and being associated with lower mortality.
Bryan Johnson · Magnesium · uses
- Takes 400 mg of Magnesium Threonate before bed for sleep.
- Takes 400 mg of Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of Magnesium Threonate before bed for sleep.
- He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of Magnesium Threonate before bed for sleep.
- Takes 400 mg of Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of magnesium L-threonate before bed for sleep.
- He takes 400 mg of Magnesium L-Threonate before bed for sleep.
- Takes 400 mg of magnesium threonate before bed for sleep.
- Used to take Resveratrol for longevity but stopped due to lack of clear benefits.
- Takes Athletic Greens AG1 in the morning for gut health.
- Mentions extra virgin olive oil is better than resveratrol.
- Mentions resveratrol as less powerful than Premium Extra Virgin Olive Oil.
Peter Attia · Magnesium · neutral
- Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
- States there is some evidence that increasing dietary potassium through potassium-rich foods like bananas and potatoes, rather than supplements, can lower blood pressure.
- Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
- Uses resveratrol extending mammalian life as an example of something complicated that can be effectively disproved through repeated randomized controlled experiments.
- Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
- Is completely convinced that resveratrol has zero benefit whatsoever and is an absolutely useless molecule, calling it a "fiasco" and a "debacle."
- States that it was clear to him by about 2010 that resveratrol was not going to work for aging, and it probably slowed down investor interest in the field.
- Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
- Recommends magnesium for optimizing bone mineral density, suggesting a daily intake of 300 to 500 milligrams as a minimum, but personally aims for about a gram.
- States that Resveratrol is 'garbage' and that there's no reason to believe it affects the biology of aging or acts as a longevity drug, citing a famous experiment where it only extended lifespan in mice on a poisonous diet by preventing liver expansion.
- States there is no reason to believe resveratrol affects the biology of aging or is a longevity drug, despite its continued popularity and sales, and recounts a famous experiment where its supposed lifespan extension in mice was due to preventing a bizarre phenomenon caused by a toxic diet.
- Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede the metabolism of vitamin D because magnesium is a cofactor in its enzymatic conversion.
- Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede vitamin D metabolism because magnesium is a co-factor in the enzymatic conversion of vitamin D.
- Takes magnesium as a straightforward supplement.
RAL Summary
Members OnlyTier 4 for Occasional Heartburn: Fast Relief
Magnesium has human support for heartburn, but mainly as part of antacid mixtures, and the other ingredients have thin, mixed or animal-only evidence. There are no reviews yet, so the evidence is thin and Tier 4 fits.
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 11 of the 42 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Digestive system, Urinary system
Combine with: Combine with a healthy diet and lifestyle.
Possible side effects: In one trial, a drink containing vitamin B6 with other ingredients caused heartburn in 10 of 25 people, and heartburn was commonly reported with meds containing potassium. No reviews have been read.
Supplement Facts
Vitamin B6 100 mg · Magnesium 200 mg · Potassium 100 mg
| Vitamin B6 | 100 mg | |
| Magnesium | 200 mg | |
| Potassium | 100 mg | |
| Uva Ursi | 1.2 g | † |
| Dandelion | 1.15 g | † |
| Green Tea | 200 mg | † |
| Evodiae fructus | 100 mg | † |
| Resveratrol | 37.5 mg | † |
Other ingredients: Wheat Flour, Gelatin, Titanium Dioxide.
Directions: Directions: Take 5 capsules 2 times daily, preferably 5 capsules after breakfast and 5 capsules after lunch. Drink an additional 8 oz. of water with each serving. For best results begin taking Carve 3-5 days before any scheduled event.
Barcode (UPC) 608938406088 · Label source: NIH label database · Report a label change
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Our articles on this subject
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Graded November 14, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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