Kyolic Formula 103 Review

Kyolic Aged Garlic Extract - Immune Formula 103 is a capsule supplement from Wakunaga of America Company that the page describes as combining vitamin C, astragalus and mushrooms. The product description states that Kyolic Aged Garlic Extract begins with 100% organically grown garlic bulbs. The bulbs are then aged in a unique extraction process that the page says eliminates odor and creates beneficial compounds found only in Kyolic. The page says this combination of vitamins, mushrooms and herbs helps to support healthy immune function. The label lists each serving as two capsules, with 100 servings per bottle, and the product is sold as a 200 capsule bottle. Each serving provides 105 mg of vitamin C as calcium ascorbate, which the page lists as 175 percent daily value. The formula also includes 440 mg of aged garlic extract powder from the bulb, 150 mg of premium mushroom complex made from shiitake, maitake, poria cocos, reishi and agaricus, 100 mg of astragalus extract from the root, 100 mg of oregano extract from the leaf, and 80 mg of olive leaf extract standardized to 18 percent oleuropein. The other ingredients are gelatin and magnesium stearate from a vegetable source. The page states the product is preservative free and free of artificial sweeteners, flavors and colors. The directions say to take two capsules with a meal twice daily. The warning asks that the product be kept out of reach of children. The specifications list the form as capsules, the product weight as 6 oz, and the item number as WA-1010 with 1125054. The allergen section marks the product as egg free, fish free, milk free, peanut free, shellfish free, soy free, tree nut free and wheat free, and specialty diet notes include corn free, dairy free, salt free, starch free, sugar free and yeast free. The page also shows a nutritionist verified badge updated January 15, 2026, from the Vitamin Shoppe wellness team. The page lists a price of 28.99 dollars, which equals about 0.28 dollars per serving in the page's own calculation.

Product Focus: CirculationAlso covers:HeartImmune system
Tier ⓘ
Tier 2 · Rank 14
Tier 2 · Researched. Human studies show improvement in an aging-related function or a specific goal, and the reviews agree. Rank 14 within Tier 2 for Circulation; 14 of 57 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
88 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
97% of 131
Biohacker Mentions
10 of 10
Cost per month
$35 at 2 servings

Study, Trial or Testing Result Summary

Members Only110 human studies · 76 improved

28 of these 110 human studies gave the ingredient by drip or injection, not by mouth.

110 human studies76 improved16 no effect14,516 people studied

This product itself was tested in 3 human studies.

The main ingredient, aged garlic extract, has the strongest support for blood flow. A review of 12 trials in 553 people with high blood pressure found garlic lowered the top number by about 8 points and the bottom by about 5.5, and aged garlic extract made arteries less stiff [1]. In 49 people with uncontrolled high blood pressure, Kyolic aged garlic extract lowered blood pressure and artery stiffness versus placebo [2]. A year of aged garlic extract raised skin blood flow in people at raised heart risk [3], and 400 mg daily reduced artery stiffness in obese adults [4]. These trials tested garlic alone, often at 1.2 grams, more than the 880 mg in two servings here. Olive leaf is at a studied dose but results are mixed: one trial lowered blood pressure [5], another found no benefit over placebo [6]. Vitamin C helped vessel widening at 500 mg [7], but this product gives 210 mg, below that dose, and a large review found no overall effect on artery stiffness [8]. Astragalus studies mostly used injections or herb mixes [9]. Oregano was only tested as a skin application of its main compound [10]. The mushroom complex has no human studies. Animal and cell studies are never counted.

See all 110 studies →Hide the studies

Review Totals and Summary

Members Only131 reviews · 97% positive
131 reviews · Vitacost 75 · Walmart 35 · PureFormulas 12 · The Vitamin Shoppe 5 · King Soopers 1 · Ralphs 1 · Blue Sky Vitamin 1 · Foodsco 1
97% positive1% neutral2% negative

Buyers rate Kyolic Formula 103 capsules very highly, with about 130 ratings across the stores. Most are from long-term users who take it for immune support. The few complaints concern allicin content, one filler ingredient and the vitamin C source, and a single serious allergic reaction. **What buyers say it did for them:** Most describe steady immune support over many years. One says "Have used them for over 10 years!" and another credits it with staying healthy through two flu seasons without a flu shot. One reviewer thinks it "Seemed to speed up the healing" of shingles. A Vitacost buyer reports getting sick less often, and a PureFormulas reviewer mentions fewer sinus infections. Others are still judging: one has used it for only a month, and another is waiting to see whether it prevents colds. These are personal impressions, not proof. **What they complain about:** Complaints are few. One 3-star reviewer says it "doesn't contain the amount of Allicin in the Supplement facts." A Vitacost reviewer calls the quality good apart from one filler and dislikes the vitamin C source, wishing it were food-based. The one 1-star review reports a severe reaction in the reviewer's husband, with facial swelling, hives and digestive trouble. The reviewer blames the astragalus in the formula, because a separate astragalus product caused the same reaction. **Taste, smell and form:** This is the most repeated praise. Buyers like the lack of garlic taste or odor: "No garlic odor. No colds." One says "I hardly notice it," and another notes "no aftertaste like may happen with other garlic products." A reviewer who struggles with strong-tasting pills says these go down easily. Another mentions no stomach ache. Pill size is not criticized, and a Blue Sky Vitamin buyer calls the capsules easy to swallow and odorless. **Value for money:** Opinion on price is positive. One buyer says "I think the price is very fair for the quality," and another says this is "same product sold in health food stores for more." A Piping Rock reviewer says they could not find this much product for the money elsewhere. A Vitacost buyer chose it over a pricier brand, believing the ingredients were the same. **Who it seems to suit:** It suits people who want a garlic-based immune supplement without the smell or aftertaste, and those who value a trusted brand. Several say it combines what they need, so "no need to take the individual products." Repeat buyers are common, and many take it daily or through the winter. One reviewer uses it for heart and general health, and another for candida support. It did not suit the one person who reacted badly, and it may disappoint anyone who cares about the allicin amount or filler ingredients. Buyers sensitive to astragalus should note that complaint. Reviews of other forms of this product, such as gummies or powder, were left out; this summary covers the capsules only.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

Garlic is the main ingredient, and most of the panel leans positive: five of the ten recommend it and three more use it, while one warns and one says he does not eat it. Panelists take it for gut health, blood pressure and cholesterol, with one favoring aged garlic extract backed by human trials, and one using a 600 milligram capsule whenever he takes Alpha-GPC. Others eat it as food, paired with avocado or in a dressing, or at breakfast. The caution comes from one panelist who says eating a lot of garlic left his brain feeling less sharp, and who notes a bleeding risk for anyone on meds, so he advises using it strategically. Vitamin C and oregano are smaller ingredients in this product, and vitamin C draws mostly positive comments, mainly for collagen and immune support.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Garlic · recommends
    • 5 Nov 2026 · recommends · YouTube ↗
      Recommends garlic, explaining that crushing it releases allicin, which activates fat burning in the liver and significantly reduces liver enzymes.
    • 7 Nov 2026 · Vitamin C · warns · Facebook ↗
      Warns against generic multivitamins, stating they are often full of fillers and synthetics.
    • 6 Nov 2026 · Vitamin C · neutral · Instagram ↗
      Mentions that bleeding or swollen gums point to vitamin C deficiency, and sugar competes with it directly, reducing absorption.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
    • 25 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Dr. Berg states that Vitamin C helps fight biofilms and is essential for making collagen in gums, teeth, and capillaries.
    • 24 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C as a cofactor, especially for collagen.
    • 23 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that high doses of vitamin C, like 2 to 4 grams, can greatly reduce inflammation and support the immune system.
    • 18 Oct 2026 · neutral · Facebook ↗
      Garlic supports detoxification, contains allicin, is antimicrobial, supports a healthy heart, supports healthy blood pressure, may have anticancer benefits, supports healthy gut microbes, and is a potent anti-inflammatory.
    • 17 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Highly recommends taking natural food vitamin C, about 500 mg, at the first sign of a cold.
    • 16 Oct 2026 · recommends · Instagram ↗
      Dr. Eric Berg recommends adding garlic to eggs to support satiety, antioxidant potential, cardiovascular, and liver health.
    • 11 Oct 2026 · recommends · YouTube ↗
      Recommends mixing one drop of garlic with five drops of povidone iodine for a wart and skin tag remedy, suggesting to crush the garlic.
    • 3 Oct 2026 · recommends · Facebook ↗
      Recommends garlic for its chelation abilities and its ability to turn up the body's detoxification genes.
    • 2 Oct 2026 · recommends · YouTube ↗
      Recommends putting some garlic on skin tags to help them go away quickly.
    • 1 Oct 2026 · recommends · YouTube ↗
      Recommends chewing one clove of garlic every single day, noting that it has a unique compound called allicin which is highly antimicrobial and can cause the liver to detoxify poisons, get rid of pathogens, increase nitric oxide, decrease blood pressure, and act as a med.
  • Dr. Mark Hyman · Garlic · recommends
    • 25 Oct 2026 · recommends · Instagram ↗
      Recommends garlic as a fibrous food to heal the gut.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 7 Oct 2026 · Vitamin C · neutral · Podcast ↗
      Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
    • 7 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Mentions topical vitamin C as an antioxidant that can help skin with aging.
    • 6 Oct 2026 · Vitamin C · neutral · X ↗
      Mentions that what they do when a cold comes on is not just vitamin C.
    • 5 Oct 2026 · uses · YouTube ↗
      Eats a lot of garlic and includes it in his chicken soup and a special drink because it is an antimicrobial and antiviral.
    • 5 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends ensuring adequate vitamin C intake on a regular basis for immune support, stating it's important for healthy immune function despite mixed data on its effectiveness for colds.
    • 5 Oct 2026 · Astragalus · uses · YouTube ↗
      Puts astragalus, a Japanese herb, into his chicken soup because it has a huge effect on the immune system and improves immune response.
    • 30 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that vitamin C was the very first vitamin discovered, isolated, and synthesized in 1932, and its deficiency caused scurvy.
    • 14 Sep 2026 · Vitamin C · recommends · Facebook ↗
      Recommends nutrient-dense foods rich in vitamin C, such as guavas and parsley, to reduce inflammation.
    • 9 Sep 2026 · Vitamin C · uses · YouTube ↗
      Used intravenous vitamin C cocktails to help him detoxify and recover from chronic fatigue.
    • 27 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C for immune system support and modulation.
    • 22 Jul 2026 · Vitamin C · uses · YouTube ↗
      Relies on Big Bold Health's HTB Immune Energy Chews, which deliver 1000mg of sprouted Himalayan tardy buckwheat, along with vitamin C, D, magnesium, and zinc, to support immune balance, resilience, energy, and focus.
    • 26 May 2026 · neutral · X ↗
      Notes that crushing garlic and letting it rest for 10 minutes before cooking activates an enzyme that significantly increases its cancer-fighting and heart-protective compounds.
  • Siim Land · Garlic · recommends
    • 7 Oct 2026 · recommends · Instagram ↗
      Recommends Aged garlic extract for blood pressure and cholesterol, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 6 Oct 2026 · neutral · X ↗
      Lists Aged garlic extract as one of 15 supplements backed by human studies.
    • 30 Sep 2026 · Vitamin C · neutral · X ↗
      Lists sauerkraut and fruit as sources of Vitamin C.
    • 15 Sep 2026 · recommends · Instagram ↗
      Says garlic is an old food with health benefits, especially good for lipids and the immune system.
    • 12 Sep 2026 · recommends · YouTube ↗
      Says garlic has benefits for the immune system and the cold, and advises crushing or chopping it and letting it sit for 10 minutes before heating or eating it to preserve its health benefits.
    • 6 Sep 2026 · Vitamin C · neutral · X ↗
      Notes that Vitamin C is one of several supplements with human evidence.
    • 7 Aug 2026 · neutral · YouTube ↗
      Mentions aged garlic extract as a compound that can increase autophagy, but notes it doesn't come close to exercise in effectiveness.
    • 27 Jul 2026 · Vitamin C · neutral · X ↗
      Notes that researchers found vitamin C alleviates ferro-aging, a process of iron overload and lipid peroxidation that drives aging, and that it directly inhibited ACSL4, a protein driving ferro-aging.
    • 27 Jul 2026 · Vitamin C · neutral · X ↗
      States that Vitamin C has a central role in aging and longevity, and that in monkeys, oral vitamin C slowed ovarian aging during a 3.3-year study.
    • 27 Jul 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is one of the most important vitamins for staying healthy and aging well, and that intakes of 200 to 400 mg a day from food or supplements largely saturates plasma and neutrophils in most healthy adults. He also recommends spreading out the vitamin C across the day to avoid oversaturation.
    • 9 Jul 2026 · Vitamin C · neutral · YouTube ↗
      Mentions vitamin C in comparison to topical melatonin for oxidative defense, stating that melatonin would compete but is not as broadly validated clinically.
    • 4 Jul 2026 · Vitamin C · uses · YouTube ↗
      Was found to be vitamin C deficient by True Health and Mayo Clinic tests, and now addresses this by eating one extra kiwi fruit daily.
  • Andrew Huberman · Garlic · uses
    • 1 Oct 2026 · uses · YouTube ↗
      Makes it a point to ingest a 600 milligram capsule of garlic anytime they take Alpha-GPC to offset potential increases in TMAO.
    • 27 Jul 2026 · recommends · YouTube ↗
      He suggests taking 600 milligrams of garlic, which contains allicin, to inhibit TMAO production, especially when taking Alpha GPC regularly, and notes that garlic capsules are inexpensive and don't cause bad breath.
    • 17 Jun 2026 · Vitamin C · uses · X ↗
      Takes a multivitamin every day for longevity.
    • 2 Feb 2026 · Vitamin C · recommends · YouTube ↗
      Recommends AG1, a vitamin, mineral, and probiotic drink, and notes that for a limited time, a subscription comes with additional supplements.
    • 7 Jul 2025 · Vitamin C · uses · YouTube ↗
      Takes an extra gram of vitamin C a day for its effects on immunity and potential synergy with collagen.
    • 16 Jun 2025 · Vitamin C · uses · YouTube ↗
      Found the Met RX Big 100 Bar to be 'magic' on the trail because it's a hunk of calories with protein and fortified with vitamins and minerals, despite being something they would never eat in normal life.
    • 28 Apr 2025 · Vitamin C · uses · YouTube ↗
      Started taking AG1 in 2012 and still takes it every single day to ensure he meets his quota for daily vitamins and minerals and to support gut health, which is critical for proper brain function, immune system, and neurotransmitter production.
    • 3 Feb 2025 · Vitamin C · uses · YouTube ↗
      Has been taking AG1 daily since 2012 because it is the highest quality and most complete foundational nutritional supplement, ensuring he gets all necessary vitamins, minerals, and micronutrients for daily health.
    • 18 Nov 2024 · Vitamin C · uses · YouTube ↗
      Has been drinking AG1 since 2012, finding it difficult to get enough vitamins, minerals, micronutrients, and adaptogens from diet alone. He finds that taking AG1 daily improves all aspects of his health, including physical and mental health, performance, recovery from exercise, and immune system strength, and also notices more mental clarity and energy.
    • 14 Oct 2024 · Vitamin C · recommends · YouTube ↗
      Recommends AG1 as the highest quality and most complete foundational nutritional supplement, containing vitamins, minerals, probiotics, prebiotics, and adaptogens to cover dietary gaps and support a demanding life.
    • 12 Aug 2024 · Vitamin C · uses · YouTube ↗
      States that AG1 is the highest quality and most complete foundational nutritional supplement available, containing vitamins, minerals, probiotics, prebiotics, and adaptogens, and that he has been taking it daily since 2012, often twice a day, to bolster his energy, immune system, and gut microbiome.
    • 2 Aug 2024 · Vitamin C · recommends · YouTube ↗
      Huberman mentions that vitamin C seems to help with the absorption or utilization of collagen protein.
    • 29 Jul 2024 · neutral · YouTube ↗
      Mentions that if one takes Alpha GPC, they would have to take 600 milligrams of garlic to offset the increase in TMAO, if one believes TMAO matters. He prefers to just eat garlic anyway.
    • 1 Jul 2024 · recommends · YouTube ↗
      Agrees with a dermatologist's recommendation to ingest garlic because it contains sulfur, which is key for collagen synthesis and repair.
  • Thomas DeLauer · Garlic · recommends
    • 25 Sep 2026 · recommends · YouTube ↗
      Recommends using garlic along with avocado in the same meal to feed the same microbes and compound the positive effects on gut health.
    • 6 Nov 2026 · Vitamin C · recommends · YouTube ↗
      Recommends whole food vitamin C, found in kiwi fruit, citrus, and bell peppers, to help clear uric acid by competing at kidney transporters, preventing reabsorption.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 4 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
    • 29 Sep 2026 · Vitamin C · uses · YouTube ↗
      Takes Purity's liquid liposomal vitamin C for immune support and overall wellness, finding it easy to add to water, juice, or take straight up due to its good taste.
    • 25 Sep 2026 · neutral · Facebook ↗
      Notes that garlic's allicin converts to hydrogen sulfide, which relaxes vessel walls.
    • 18 Sep 2026 · Vitamin C · neutral · Facebook ↗
      Compares the Vitamin C content of oranges (53mg) to guava (228mg), noting guava has 4x more.
    • 5 Sep 2026 · uses · YouTube ↗
      Includes garlic in their homemade mineral broth, noting its detoxifying properties as part of a detoxification protocol.
    • 29 Aug 2026 · Vitamin C · neutral · Instagram ↗
      States that collagen synthesis is vitamin C dependent, in the context of glowing skin.
    • 25 Aug 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C for sleep, noting that intake in the range of 125 to 200 mg per day is associated with a lower risk of sleep disorders and sleep apnea, with the benefit plateauing beyond this range.
    • 19 Aug 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming a little bit of vitamin C, such as a couple of berries or kiwi, along with flavanol-rich cocoa to help the delicate flavanols hold up and prevent oxidation in the gut.
    • 8 Aug 2026 · Vitamin C · neutral · YouTube ↗
      Explains that vitamin C improves the ability of neutrophils to engulf bacterial infections, and that they have a greater ability to engulf larger infections.
    • 9 Jun 2026 · recommends · YouTube ↗
      Garlic is recommended for its inulin content.
  • Dave Asprey · Garlic · warns
    • 13 Sep 2026 · warns · X ↗
      Likes garlic but notices their brain feels less sharp when they eat a lot of it, even tracking the effect with EEG, and advises using it strategically, especially if it affects cognition.
    • 3 Nov 2026 · Vitamin C · neutral · YouTube ↗
      Recounts a doctor telling him in his 20s that vitamin C would kill him.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 7 Oct 2026 · Vitamin C · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 4 Sep 2026 · warns · Podcast ↗
      Host Dave Asprey separates what the human data actually supports regarding raw garlic, modest blood pressure and cholesterol effects, real antimicrobial properties, and a genuine bleeding-risk caution for anyone on meds, from the unproven parasite-cleanse and brain fog claims driving the trend online.
    • 14 Aug 2026 · Vitamin C · neutral · Podcast ↗
      Dave Asprey reflects on how new research clarifies the mechanism behind IV vitamin C's anti-cancer effect, vindicating a decades-old idea that was dismissed for the wrong reasons.
    • 25 Jul 2026 · Vitamin C · neutral · Facebook ↗
      Notes that plain Vitamin C isn't enough and that most people never think to check for a specific ingredient that makes it work.
    • 16 Jul 2026 · Vitamin C · warns · YouTube ↗
      Dave Asprey recommends taking maybe a gram of vitamin C a day in divided doses, noting that plasma levels peak around 250 milligrams twice a day.
    • 14 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Qualia Vitamin C Plus, highlighting its combination of seven forms of vitamin C with 250 mg of citrus bioflavonoids, which helps with absorption and use for building collagen and a strong immune system.
    • 9 Jul 2026 · Vitamin C · warns · YouTube ↗
      Warns that taking too much vitamin C can raise oxalate levels, emphasizing that everything has risk and reward.
    • 2 Jul 2026 · Oregano · recommends · YouTube ↗
      Recommends adding oregano to oil halfway through cooking to provide additional antioxidants and protect the oil, or when using butter at the end for flavor.
    • 14 Jun 2026 · Vitamin C · recommends · Podcast ↗
      Recommends Vitamin C as the real biological fix for deep focus issues, explaining how the brain hoards it at levels 100 times higher than blood and how to bypass the blood-brain barrier.
    • 27 May 2026 · Vitamin C · warns · YouTube ↗
      States that Ensure is like SlimFast but worse, and that its ingredients, including synthetic vitamins, guar gum, maltodextrin, high fructose corn syrup, and seed oils, are disgusting and should not be given to sick or well people.
    • 2 Apr 2026 · Oregano · neutral · TikTok ↗
      States that oregano regulates gut bacteria.
  • Dr. Rhonda Patrick · Garlic · uses
    • 8 Sep 2026 · uses · Facebook ↗
      Rhonda's current diet includes a homemade salad dressing made with avocado, garlic, apple cider vinegar, and olive oil.
    • 25 Aug 2026 · Vitamin C · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 5 Jun 2026 · Vitamin C · recommends · Instagram ↗
      Recommends nutrients like vitamin C for men to prioritize sperm mitochondrial health.
    • 4 May 2026 · Vitamin C · uses · YouTube ↗
      Dr. Rhonda Patrick's daughter chugs an Emergency fizzy drink in the morning to ensure she gets some vitamin C and micronutrients before school.
    • 5 Feb 2026 · Vitamin C · recommends · Facebook ↗
      Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
    • 9 Jan 2026 · Vitamin C · neutral · Facebook ↗
      Notes that ~35% of Americans are low in vitamin C.
    • 29 Dec 2025 · Vitamin C · recommends · X ↗
      Recommends increasing vitamin C intake if concerned about skin aging, noting it is an essential cofactor for collagen synthesis.
    • 9 Sep 2025 · Vitamin C · warns · YouTube ↗
      Suggests avoiding a multivitamin if it contains biotin before a testosterone blood test to prevent confounding results.
    • 4 Sep 2025 · Vitamin C · neutral · Facebook ↗
      Multiple randomized controlled trials show older adults taking a standard multivitamin (like Centrum Silver) had measurable improvements in processing speed, cognition, and episodic memory.
    • 11 Aug 2025 · Vitamin C · uses · X ↗
      Currently takes the Pure Encapsulations O.N.E Multivitamin.
    • 26 Jun 2025 · Vitamin C · uses · Facebook ↗
      Rhonda's current supplement routine includes Vitamin C.
    • 8 Jun 2021 · recommends · YouTube ↗
      Suggests that if someone is an 'immuno-ager,' they might want to take garlic to help with their immune system.
    • 11 Aug 2015 · uses · YouTube ↗
      Used a concoction of garlic and grapefruit seed extract, applied both topically and orally, to successfully treat MRSA after meds failed.
    • 21 Jul 2014 · neutral · YouTube ↗
      Rhonda Patrick points out that garlic is very high in sulfur-containing compounds like beta-mercaptans.
  • Bryan Johnson · Garlic · uses
    • 1 Jul 2026 · uses · X ↗
      Uses garlic as part of their breakfast.
    • 1 Jul 2026 · Oregano · uses · X ↗
      Uses oregano as part of their breakfast.
    • 12 Jun 2026 · uses · X ↗
      Eats garlic for breakfast.
    • 12 Jun 2026 · Oregano · uses · X ↗
      Eats oregano for breakfast.
    • 16 Oct 2025 · uses · YouTube ↗
      Uses garlic, noting it has been shown to lower blood pressure and help the immune system.
    • 3 Feb 2025 · Vitamin C · neutral · YouTube ↗
      Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
    • 8 Jan 2025 · Vitamin C · uses · YouTube ↗
      Applies vitamin C after showering.
    • 2 Jul 2024 · uses · YouTube ↗
      Includes one odor-free garlic pill in his Blueprint stack.
    • 9 Dec 2023 · uses · YouTube ↗
      Adds one peeled clove of garlic to his Super Veggie for heart and immune health.
    • 26 Sep 2023 · Vitamin C · uses · YouTube ↗
      Takes 250 milligrams of Vitamin C.
    • 27 Jul 2023 · uses · YouTube ↗
      Includes garlic in his Super Veggie meal, which he eats at 7 AM.
    • 21 Jun 2023 · uses · YouTube ↗
      Takes garlic for liver enzymes and cholesterol management, and also eats it daily as part of his super veggie.
    • 25 Jan 2023 · uses · YouTube ↗
      Includes garlic in his daily 'Super Veggie' breakfast for its nutrient density.
    • Date not recorded · uses · Source ↗
      Uses chopped garlic in his Super Veggies.
  • Ben Greenfield · Garlic · recommends
    • 23 May 2026 · recommends · YouTube ↗
      Recommends root spices like garlic for use on the AIP diet.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 24 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
    • 24 Sep 2026 · Astragalus · neutral · YouTube ↗
      Mentions Astragalus as one of the Chinese herbs used, noting its potential in decreasing the rate at which telomeres shorten.
    • 25 Aug 2026 · Vitamin C · neutral · X ↗
      Notes that IV vitamin C has been used for decades for cancer patients with almost no standardization and that he receives many questions about its effectiveness and combination with chemo.
    • 9 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C for skin repair post-tattoo.
    • 7 Mar 2026 · Vitamin C · warns · YouTube ↗
      Does not agree that ascorbic acid is vitamin C, comparing it to calling chaff wheat, and notes that it is made from genetically modified cornstarch or corn syrup byproducts using solvents.
    • 26 Jan 2026 · Oregano · neutral · Facebook ↗
      Oregano was mentioned in a study as a biofilm disruptor that can improve microbial access and affect outcomes in SIBO and methane-dominant cases.
    • 22 Nov 2025 · Vitamin C · warns · YouTube ↗
      Warns against ascorbic acid, stating that it does not cure scurvy and that the world has been led astray by the deception around it versus the whole food vitamin C complex.
    • 16 Nov 2025 · Vitamin C · warns · Facebook ↗
      Warns against taking 1,000 mg of vitamin C immediately after a workout for individuals under 50, as it can dull the body's natural adaptation signal.
    • 30 Oct 2025 · Vitamin C · warns · YouTube ↗
      Warns that using high-dose antioxidants like vitamin C directly before or after a hyperbaric session is not a great idea, as it could impair some of the effects by reducing reactive oxygen species.
    • 9 Oct 2025 · Vitamin C · warns · YouTube ↗
      Warns that taking a whole bunch of antioxidants like vitamin C after a workout can suppress the body's inflammatory response, which is necessary for benefits like mitochondrial proliferation and satellite cell generation for new muscle.
    • 2 Sep 2025 · Oregano · uses · Facebook ↗
      Stuffs the trout with herbs like oregano.
  • Peter Attia · Garlic · uses
    • 31 Dec 2019 · uses · YouTube ↗
      States that he does not eat garlic.
    • 3 Jul 2025 · Vitamin C · stopped · YouTube ↗
      Recommends vitamin C as an important molecule for skin, noting its role as a precursor for collagen synthesis, a powerful antioxidant, and a regulator of complexion for even skin tone.
    • 29 Jun 2025 · Vitamin C · stopped · YouTube ↗
      Tried a vitamin C serum mixed with ferulic acid but stopped using it because she hated the smell. She notes that topical application of vitamin C far exceeds the levels achievable by ingestion for skin benefits.
    • 6 Sep 2024 · Vitamin C · neutral · YouTube ↗
      States that vitamin C deficiency is associated with an elevated risk of cataract, but supplementation to supranormal levels has not been shown to protect against cataract formation.
    • 19 Aug 2024 · Vitamin C · recommends · YouTube ↗
      Mentions the elimination of scurvy through the work of James Lind and the eventual understanding that it was due to vitamin C, initially thought to be just citrus.
    • 7 Mar 2022 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C deficiency is associated with an elevated risk of cataract, supplementation to supranormal levels has been conclusively shown not to protect against cataract formation.
    • 24 Jan 2022 · Vitamin C · neutral · YouTube ↗
      Mentions that a survey of doctors showed they recommend Vitamin C for COVID-19, but notes there is no real evidence behind it.
    • 19 Oct 2020 · Vitamin C · warns · YouTube ↗
      Expresses skepticism about 'panacea treatments' for cancer, specifically mentioning a 'twenty thousand dollars of vitamin C' treatment, implying it's an example of something he's 'squirrely' about due to cost and unproven claims.
    • 10 Aug 2020 · Vitamin C · recommends · YouTube ↗
      Asks if vitamin C matters for immune function, suggesting a need for a definitive study.
    • 12 Mar 2020 · Vitamin C · warns · YouTube ↗
      Warns against the "total nonsense" of taking excessive amounts of vitamin C, especially in specific forms like liposomal vitamin C, for immunity, stating that it is idiotic and potentially dangerous to think it will offer immunity.
    • 6 Feb 2020 · Vitamin C · neutral · YouTube ↗
      Would love to see more research done on mega dose intravenous vitamin C for viral infections, noting some interesting but not followed-through research from the 1960s.

RAL Summary

Members OnlyTier 2 for Circulation

Tier 2 fits: several placebo-controlled human trials and a review show aged garlic extract, the main ingredient, lowers blood pressure and artery stiffness [1][2], and 94% of 141 reviews are positive.

Take 2 servings a day (4 capsules) to match the dose that worked in the studies.

This product itself was tested in 3 human studies.

Where the evidence disagrees: 16 of the 110 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Cardiovascular system, Immune system

Combine with: Aged garlic extract with S-allyl cysteine has clinical support for modestly improving arterial elasticity, endothelial function, and reducing arterial stiffness and plaque progression, which aligns with healthy blood flow. Synergistic options include omega-3 fish oil (EPA/DHA) for endothelial function and triglyceride support, CoQ10 (ubiquinol) for mitochondrial and vascular energy, magnesium for vascular smooth muscle relaxation, and vitamin K2 (MK-7) to help direct calcium away from arteries. L-citrulline or L-arginine can boost nitric oxide production for vasodilation, and beet root or nitrate-rich extracts add further nitric oxide support. Because garlic can have mild antiplatelet effects, consult a physician before combining with meds, high-dose fish oil, or ahead of surgery.

Possible side effects: The studies listed report no major side effects. One reviewer reported a severe allergic reaction in her husband with facial swelling, hives and digestive trouble, which she blamed on the astragalus.

Supplement Facts

Vitamin C 105 mg · Aged Garlic Bulb Extract, Powder 440 mg · Premium Mushroom Complex 150 mg
Supplement Facts
Serving Size 2 Capsule(s)
Servings Per Container 50
Amount Per Serving% Daily Value
Vitamin C105 mg
Aged Garlic Bulb Extract, Powder440 mg†
Premium Mushroom Complex150 mg†
Astragalus Root Extract100 mg†
Oregano Leaf Extract100 mg†
Olive Leaf Extract80 mg†
† Daily Value not established.

Other ingredients: Gelatin, Magnesium Stearate.

Directions: Suggested Use: Take two capsules with a meal twice daily.

Barcode (UPC) 023542103411 · Label source: NIH label database · Report a label change

Other sizes and barcodes: 200 Capsule(s), UPC 0 23542 10342 8 (not checked yet); 200 Capsule(s), UPC 0 23542 10342 8 (not checked yet)

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Our articles on this subject

Graded November 10, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.