Loomis Enzymes DGST Review
Proper digestion ensures efficient breakdown of food, allowing absorption of essential nutrients for the continual supply of energy the body needs. Additionally, the proper function of the digestive system helps reduce nutritional deficiencies and occasional gastrointestinal discomforts. DGST is presented by Loomis Enzymes as a great product when embarking on a digestive enzyme routine, or for a person with a good diet and few digestive issues. The formula is described as comprehensive: nine different enzymes, with three sources of lipase and two sources of protease, are combined in one digestive formula. The product is positioned to help the body digest enzyme-deficient foods, to aid absorption of nutrients, and to potentially reduce digestive disruptions such as bloating or gas. The page lists the SKU as DGST 180 and offers a bottle size of 180 capsules, with 30 capsule and 90 capsule options also shown in the bottle size selector. The ingredients listed are Protease, Amylase, Glucoamylase, Lactase, Diastase, Hemicellulase, Lipase, Cellulase, Invertase, Vegetable capsule, and Phytase. The page carries a caution that users should consult a physician before use if they are pregnant, nursing, taking medication, or have a medical condition. It also carries the standard disclaimer that the statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure, or prevent disease. Product images show a DGST 180 capsule bottle and its label. No price is shown because the visitor must log in to see price or purchase the item, and no customer reviews, ratings, or barcode appear on this page.
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Study, Trial or Testing Result Summary
Members Only9 human studies · 7 improved
Several placebo-controlled trials found that multi-enzyme blends eased indigestion. In 120 adults with indigestion, 400 milligrams a day of a multi-enzyme blend for about 2 months improved indigestion-related quality of life, pain and sleep compared with placebo, with no side effects [1]. In 40 people with indigestion, 150 milligrams a day of a multienzyme complex for 60 days improved all symptom scores more than placebo [2]. This product gives about 732 milligrams a day of its blend, above the amounts studied. However, the label does not list how much of each enzyme it holds, and the studied blends were not this exact formula. A trial of 203 people found an enzyme tablet helped about 80 percent of people, about as well as another enzyme product, but it had no placebo group [3]. For fast relief, the only short study was an open-label trial in 50 older adults, where an enzyme and probiotic syrup reduced indigestion within 5 days [4]. Enzymes also eased gas, bloating and pain after stomach bypass surgery [5], and an enzyme mix reduced pain and bloating in people with bowel disease [6]. Most other trials lasted weeks, so quick relief after a single meal is less well tested. Animal and cell studies are never counted.
See all 9 studies →Hide the studies
- In 203 people with dyspepsia, a compound digestive enzyme tablet taken three times daily for 2 weeks worked about as well as an enzyme capsule (80.2% vs 79.4% effective), with few mild side effects; there was no placebo group.[Efficacy of compound digestive enzyme tablet for dyspeptic symptoms: a randomized double-blind parallel controlled mult…
- In 120 adults with functional dyspepsia, 400 mg a day of a multi-enzyme blend for 2 months improved dyspepsia quality of life, pain severity and sleep quality compared with placebo, with no side effects.Efficacy of digestive enzyme supplementation in functional dyspepsia: A monocentric, randomized, double-blind, placebo-c…
- In 60 people with digestive symptoms after gastric bypass surgery, 2 weeks of digestive enzymes or probiotics improved gas, bloating, belching, heartburn and abdominal pain scores, with no placebo group.Effect of probiotics on postoperative quality of gastric bypass surgeries: a prospective randomized trial.
- In 43 people with inflammatory bowel disease and irritable bowel symptoms, adding a beta-glucan, inositol and digestive enzyme mix for 4 weeks reduced abdominal pain, bloating and gas compared with standard treatment alone.Beta-glucan, inositol and digestive enzymes improve quality of life of patients with inflammatory bowel disease and irri…
- In 40 people with functional dyspepsia, 150 mg a day of a multienzyme complex for 60 days improved all dyspepsia symptom scores more than placebo, with no product-related side effects.Evaluation of the Safety and Efficacy of a Multienzyme Complex in Patients with Functional Dyspepsia: A Randomized, Doub…
- In 90 people with irritable bowel syndrome, a mix of beta-glucan, inositol and digestive enzymes improved bloating, gas and abdominal pain compared with no treatment, but had no effect on other symptoms.Effect of beta-glucan, inositol and digestive enzymes in GI symptoms of patients with IBS.
- In an open-label study of 50 older adults with indigestion, a Bacillus coagulans and digestive enzyme syrup taken daily for 5 days reduced dyspepsia severity more than placebo syrup, with fewer abdominal pain and gas complaints, and no major side effects.A prospective, randomized, open-label, placebo-controlled comparative study of Bacillus coagulans GBI-30,6086 with diges…
- In 249 people with functional dyspepsia treated with a compound digestive enzyme product, blood levels of several proteins predicted which patients responded poorly, but the abstract does not report the overall share who improved, the dose, or the treatment length.A preliminary exploration of a predictive model and nomogram for the efficacy of compound digestive enzyme therapy based…
- In an uncontrolled online survey after 4 weeks of a FODMAP-targeting digestive enzyme blend, most people reported less bloating and gas (78%) and less abdominal pain (65%), though no control group was included.FODMAP-Targeting Digestive Enzyme Blend for Management of Gastrointestinal Symptoms: A "Real-World" Pre-Post Interventio…
Review Totals and Summary
Members Only7,600 reviews · 95% positive
I could not find any real customer reviews of DGST, so I can't give you genuine themes from customer feedback. My searches covered the manufacturer's page, a practitioner supplement store, SuppCo, KusogLife, the BBB profile and an Amazon search. The Amazon search returned unrelated competitor products instead of a DGST listing with ratings. SuppCo had no TrustScore for the product and no user reviews. The other pages were product or catalog entries without review text. I won't invent praise or complaints. The evidence does show a few things. First, Loomis sells through practitioners, so most buyers probably get DGST on a clinician's recommendation. That would explain why open, consumer-style review pages are so sparse. Second, the brand's own messaging makes DGST the gentle, general-purpose choice. It is aimed at people with good diets and mild issues, not at severe digestive problems. Anyone with more complex needs is steered toward other Loomis products. Third, independent analysts raised mainly transparency concerns. The enzyme blend is proprietary, per-enzyme amounts and activity units are not disclosed, and third-party testing for this specific product is not verified. Those gaps would likely be the main sticking point for ingredient-focused shoppers. The positives on record are the vegetarian capsule, the wide enzyme range and the brand's good BBB standing. If you need real user sentiment, check practitioner dispensary portals such as Fullscript. You could also check the manufacturer's own site reviews or ask clinicians who dispense it. I could not verify any of those from here.
Biohacker Summary
Members Only7 of 10 recommend it
Only one of the ten panelists spoke about the enzyme blend, which is the main ingredient in this product, so there is no group view to report. That person recommends taking a blend of different enzymes as nutritional help when eating certain foods. They say it matters most for people who eat mostly cooked, canned, or pasteurized food. No doses, preferred forms, pairings, cautions, or anyone who stopped were mentioned.
See all 1 biohackers →Hide the biohackers
Dr. Eric Berg · Enzyme Blend · recommends
- Recommends taking a blend of different enzymes as nutritional assistance when eating certain foods, especially if consuming mostly cooked, canned, or pasteurized food.
RAL Summary
Members OnlyTier 4 for After-Meal Comfort: Fast Relief
The 7600 review count does not appear to belong to DGST: the review search found no customer reviews of this product, and the Amazon search returned unrelated competitor products instead. Its reviews are set aside, so it is graded on its studies alone. Human studies support Proprietary Enzyme Blend (7 of 9 human studies showed an improvement), but there are not yet enough reviews to confirm it (0).
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 1 of the 9 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Digestive system
Combine with: For digestion, DGST pairs well with lipase (for fat digestion), betaine HCl or ox bile if there is low stomach acid or poor fat handling, and a probiotic or prebiotic fiber for gut flora balance. Ginger or peppermint may help with post-meal comfort. If the real interest is cellular and DNA repair, look at separate products with evidence-backed ingredients such as NAD+ precursors (NMN or nicotinamide riboside), resveratrol or pterostilbene, CoQ10 or ubiquinol, alpha-lipoic acid, and omega-3s, ideally discussed with a clinician. Better digestion from enzymes can support absorption of those nutrients, but the enzymes themselves are not anti-aging agents.
Possible side effects: The studies reported no side effects or only a few mild ones. No written reviews could be read.
Supplement Facts
Proprietary Enzyme Blend 244 mg
| Proprietary Enzyme Blend | 244 mg | † |
Other ingredients: Phytase, Cellulose, Water.
Directions: Directions for use: Take 2 capsules, 3 times daily with meals or as directed.
Barcode (UPC) 697706042016 · Label source: NIH label database · Report a label change
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Graded November 4, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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