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NOW Foods UC-II Joint Health with Undenatured Type II Collagen bottle
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NOW Foods UC-II Joint Health with Undenatured Type II Collagen Review

NOW UC-II is a nutritional supplement designed to support joint health, mobility, and flexibility. Its primary ingredient is undenatured type II collagen, a patented form of collagen derived from chicken sternum cartilage that works with the immune system to promote healthy joints.

Product Focus: Joints and MobilityAlso graded for:Bone HealthRegularity: Long-Term ReliefBlood SugarAlso covers:Immune system
Tier ⓘ
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Members see this product's tier and why. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
Members
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
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Biohacker Mentions
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Cost per month
$9
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Study, Trial or Testing Result Summary

MembersHuman studies

The main ingredient, undenatured type II collagen, is at the studied dose. In a trial of 191 people with knee osteoarthritis, 40 milligrams a day for 180 days knee symptoms than placebo and than glucosamine with chondroitin. …

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Review Totals and Summary

Members22,742 reviews
22,742 reviews · IHerb 18,608 · Amazon 4,019 · Walmart 69 · Nowfoods 46

NOW Foods UC-II Joint with Undenatured Type II Collagen, 120 Veg Capsules has amassed a substantial number of user reviews across platforms like iHerb, Amazon, and Walmart, and the sentiment from these testimonies is quite . users note in joint comfort and flexibility after introducing this supplement to their daily routines. …

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Biohacker Summary

MembersWhat our biohacker panel says

People take it for skin, joints, connective tissue, muscle, and recovery, and a also mention hair, nails, and sleep. Panelists who gave a dose named 10 grams a day, usually in the morning, with others ranging from 2.5 to 15 grams, and they prefer hydrolyzed collagen peptides, with one also using marine collagen. …

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RAL Summary

MembersThe tier and why

human studies of this product itself found for this goal.

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More Details

MembersBody systems · Combine with · Possible side effects

Body systems: Musculoskeletal system, Immune system. Combine with and possible side are for members.

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Supplement Facts

Calcium 80 mg · UC-II® Standardized Chicken Cartilage 40 mg · Aquamin® 250 mg
Supplement Facts
Serving Size 1 Capsule
Servings Per Container 120
Amount Per Serving% Daily Value
Calcium (from Aquamin)80 mg6%
UC-II® Standardized Chicken Cartilage (Providing 10 mg Total Collagen, including Undenatured Type II Collagen)40 mg†
Aquamin® (Seaweed Derived Minerals) (Lithothamnium spp.) (Whole Plant)250 mg†
† Daily Value not established.

Directions: Take 1 capsule daily at bedtime on an empty stomach.

Barcode (UPC) 733739031365 · Label source: the brand's label · Report a label change

Where to Buy

NOW Foods · iHerb
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Our articles on this subject

Graded October 24, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.