Nutrafol Men Review

Nutrafol Men is a dietary supplement sold as capsules. One serving is 4 capsules, and each container holds 30 servings, which is 120 capsules in all. The label lists these amounts per serving: Vitamin A 1500 mcg RAE, Vitamin C 60 mg, Vitamin D 62.5 mcg, Vitamin E 3.5 mg, Biotin 3000 mcg, Iodine 226 mcg, Zinc 25 mg, and Selenium 200 mcg. It also lists two blends, Synergen Complex at 1720 mg and Nutrafol Blend at 575 mg. The other ingredients are hypromellose and rice husk. No directions for use are printed in the label details provided, so check the package in your hand for any instructions. Buyer feedback is thin so far. A buyer post shares a husband's results after three months of use.

Product Focus: Thyroid HealthAlso covers:HormonesImmune system
Tier ⓘ
Tier 2 · Rank 10
Tier 2 · Researched. Human studies show improvement in an aging-related function or a specific goal, and the reviews agree. Rank 10 within Tier 2 for Thyroid Health; 10 of 61 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
77 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
70% of 6,173
Biohacker Mentions
8 of 10

Study, Trial or Testing Result Summary

Members Only227 human studies · 72 improved

2 of these 227 human studies gave the ingredient by drip or injection, not by mouth.

227 human studies72 improved106 no effect690,088 people studied

Selenium is at a full dose. In people with Hashimoto thyroiditis, a pooled analysis of 21 trials found it lowered thyroid antibodies and thyroid-stimulating hormone [1]. A second pooled analysis found similar results with no more side effects than control [2]. One review judged the evidence too weak for routine use [3]. Zinc is near the studied dose. Added to meds, it raised active thyroid hormone, though certainty was low [4]. Another review called the zinc evidence inconclusive [5]. Iodine is at a full dose. It shrank goiter in people low in iodine [6], but too much can slow thyroid recovery [7]. Vitamin D results are mixed: one pooled analysis found lower antibodies [8] and another found no significant drop [9]. Vitamin A and vitamin C are well below the doses studied [10][11]. Vitamin E alone did not change thyroid function [12]. Biotin was not shown to help the thyroid and can distort thyroid blood tests [13]. The Synergen Complex and the Nutrafol Blend are proprietary blends with no thyroid studies. Animal and cell studies are never counted.

See all 227 studies →Hide the studies

Review Totals and Summary

Members Only6,173 reviews · 70% positive
6,173 reviews · Amazon 6,011 · Walmart 162
70% positive9% neutral21% negative

No written reviews read yet.

Biohacker Summary

Members Only8 of 10 recommend it
8 of 10 biohackers on our panel recommend it

The panel is split between zinc and selenium as the main ingredient, and zinc got most of the attention, with seven of the ten speaking about it. Among them, three take or use it, one recommends it, and the rest are neutral or cautious. Reasons given include gut lining support from a zinc carnosine form, helping the body absorb vitamin C for immune support in fall and winter, wound healing and tissue repair, testosterone, and possible help with sleep. One panelist takes 15 mg in the morning, and another described a plan of 30 grams a day for one week before surgery and two weeks after, and he was the one who warned. Selenium came up with three panelists: two recommend it, one citing weak immune regulation when it runs low and another noting that farming has depleted it from soil, while one noted studies linking it to thyroid antibody levels; vitamin D was a smaller ingredient in this product and most who mentioned it take or recommend it.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Selenium · neutral
    • 8 Nov 2026 · neutral · Facebook ↗
      Notes that sardines are rich in selenium, which binds with mercury.
    • 8 Nov 2026 · Vitamin D · neutral · Facebook ↗
      Lists Vitamin D as an ingredient found in sardines.
    • 8 Nov 2026 · Iodine · recommends · Facebook ↗
      Recommends using povidone-iodine daily with a small bandage for skin tags and warts, stating it may help deactivate the virus behind these growths.
    • 8 Nov 2026 · Vitamin A · neutral · Facebook ↗
      Mentions that the body relies on healthy fats to absorb essential vitamins like A, D, E, and K, which help support skin health, moisture, and normal cell function.
    • 7 Nov 2026 · recommends · Facebook ↗
      Recommends selenium as a trace mineral, noting that modern farming practices deplete it from the soil, leading to low levels in crops.
    • 7 Nov 2026 · Zinc · recommends · Facebook ↗
      Recommends zinc as a trace mineral, noting that modern farming practices deplete it from the soil, leading to low levels in crops.
    • 7 Nov 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D3 because it's nearly impossible to get enough from food and most people don't get enough sun, advising to aim for blood levels of at least 50 to 80 ng/mL.
    • 7 Nov 2026 · Vitamin D · neutral · Instagram ↗
      Dr. Berg states that when nutrients like vitamin D are too low, fatigue and weakness can follow.
    • 7 Nov 2026 · Iodine · recommends · Facebook ↗
      Recommends iodine as a trace mineral, noting that modern farming practices deplete it from the soil, leading to low levels in crops.
    • 7 Nov 2026 · Iodine · recommends · Instagram ↗
      Dr. Eric Berg states that 80% of the body's iodine is concentrated in the thyroid, but other tissues like breast tissue, reproductive organs, and stomach also rely on iodine to function properly, emphasizing the importance of getting enough iodine even with a normally functioning thyroid.
    • 7 Nov 2026 · Iodine · uses · YouTube ↗
      Introduces his new product, Plant-based Iodine Icelandic Sea Kelp, which he uses and recommends taking one vegetable capsule delivering 200 micrograms of plant-based iodine in the morning.
    • 7 Nov 2026 · Vitamin A · warns · Facebook ↗
      Warns against generic multivitamins, stating they are often full of fillers and synthetics.
    • 7 Nov 2026 · Vitamin E · warns · Facebook ↗
      Warns against generic multivitamins, stating they are often full of fillers and synthetics.
    • 7 Nov 2026 · Vitamin C · warns · Facebook ↗
      Warns against generic multivitamins, stating they are often full of fillers and synthetics.
  • Dr. Rhonda Patrick · Zinc · neutral
    • 6 Nov 2026 · neutral · Instagram ↗
      Mentions that getting too little zinc may play a role in declining testosterone levels, and that zinc helps the body make testosterone.
    • 8 Nov 2026 · Vitamin D · neutral · Instagram ↗
      Notes that vitamin D from sunlight, food, or supplements needs to undergo conversions in the liver and kidneys to become its active hormone form, calcitriol.
    • 4 Nov 2026 · Vitamin D · neutral · Instagram ↗
      States that Vitamin D supplementation has been associated with a 40% lower dementia risk, and low levels are linked to a 50 to 80% higher risk.
    • 28 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends getting adequate vitamin D, noting that people taking vitamin D supplements have a 40% lower risk of dementia, while those with lower vitamin D have a 50-80% higher risk.
    • 5 Oct 2026 · Vitamin D · neutral · Facebook ↗
      Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
    • 30 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Mentions that vitamin D also plays a role in maintaining muscle mass.
    • 29 Sep 2026 · recommends · YouTube ↗
      Notes that not getting enough zinc can affect testosterone, as zinc is very important for testosterone synthesis.
    • 28 Sep 2026 · recommends · YouTube ↗
      Recommends men take a 30 milligram zinc supplement for sperm health when preparing for IVF.
    • 28 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Recommends ensuring adequate vitamin D intake for men's sperm health.
    • 24 Sep 2026 · Vitamin D · neutral · Facebook ↗
      Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
    • 25 Aug 2026 · Vitamin D · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 25 Aug 2026 · Vitamin E · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 25 Aug 2026 · Vitamin C · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 25 Aug 2026 · Vitamin A · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
  • Andrew Huberman · Zinc · neutral
    • 5 Nov 2026 · neutral · YouTube ↗
      Notes that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 29 Oct 2026 · uses · YouTube ↗
      Zinc carnosine to support and improve the lining of your gut.
    • 26 Oct 2026 · uses · YouTube ↗
      Notes that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 19 Oct 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 12 Oct 2026 · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 28 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut, and he was already taking some of these ingredients separately.
    • 21 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro includes zinc carnosine, which he was already taking separately, to support and improve the lining of the gut.
    • 21 Sep 2026 · Vitamin D · neutral · YouTube ↗
      Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
    • 14 Sep 2026 · uses · YouTube ↗
      Personally takes zinc carnosine, which is included in AG1 Pro to support and improve the lining of the gut.
    • 31 Aug 2026 · uses · YouTube ↗
      AG1 Pro has zinc carnosine to support and improve the lining of your gut. Some of these ingredients I personally was already taking separate from the AG1 formula.
    • 24 Aug 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of your gut.
    • 7 Aug 2026 · Vitamin D · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for longevity.
    • 20 Jul 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 20 Jul 2026 · Vitamin D · recommends · YouTube ↗
      States that Vitamin D is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
  • Ben Greenfield · Zinc · warns
    • 29 Oct 2026 · warns · YouTube ↗
      Ben Greenfield's formulation includes 30 grams of zinc a day, taken for one week before surgery and two weeks after, as it is an important cofactor for wound healing.
    • 29 Oct 2026 · Vitamin E · neutral · YouTube ↗
      Mentions a recent study showing no significant increase in bleeding for patients on Vitamin E supplementation during open heart surgery, which was interesting for him to learn.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 29 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
    • 21 Oct 2026 · Vitamin A · neutral · Instagram ↗
      Notes that Vitamin A is a fat-soluble vitamin that supports healthy skin cell turnover.
    • 15 Oct 2026 · Selenium · recommends · YouTube ↗
      Recommends taking sufficient selenium to ensure free T3 levels are right, which is important for the reverse calcium transport system.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 15 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Mentions vitamin D as part of a bare-minimum protocol.
    • 15 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
    • 15 Oct 2026 · Iodine · recommends · YouTube ↗
      Recommends taking sufficient iodine to ensure free T3 levels are right, which is important for the reverse calcium transport system.
    • 10 Oct 2026 · recommends · YouTube ↗
      Emphasizes that zinc sufficiency is crucial for immunity because the thymus-derived peptide thymulin, which trains lymphocytes, requires zinc to be active.
    • 24 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
    • 19 Sep 2026 · recommends · YouTube ↗
      Recommends adding zinc into one's stack because it is a co-factor for enzymes involved in testosterone synthesis and sperm maturation, and zinc deficiency is a reproducible cause of low sperm count.
    • 19 Sep 2026 · neutral · Podcast ↗
      He mentions zinc as a supplement with real human data behind it for male fertility.
  • Dr. Mark Hyman · Zinc · neutral
    • 29 Oct 2026 · neutral · YouTube ↗
      Explains that zinc is important for the body's repair crew, helping to heal damaged tissue, and a deficiency can lead to cuts and wounds taking longer to heal.
    • 4 Nov 2026 · Vitamin D · uses · YouTube ↗
      Consumes Zetopia's Atlantic salmon to get Vitamin D, particularly in the winter months, as it is one of the few foods that provides both Omega-3s and Vitamin D.
    • 29 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Mentions that the body makes vitamin D from sunlight exposure, and a deficiency can hinder calcium absorption, which is crucial for strong bones.
    • 26 Oct 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
    • 21 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 19 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Notes that vitamin D plays a role in immune function.
    • 19 Oct 2026 · Vitamin A · neutral · YouTube ↗
      Mentions that vitamin A levels can be looked at to get a deep sense of what's happening with nutrient levels.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 8 Oct 2026 · Vitamin D · recommends · Instagram ↗
      Recommends checking vitamin D levels and states that if they had to pick one single intervention for immune health, vitamin D would be it.
    • 7 Oct 2026 · uses · YouTube ↗
      Gave a patient with psoriatic arthritis a little zinc, which contributed to significant improvement in her condition.
    • 7 Oct 2026 · Vitamin D · neutral · Podcast ↗
      Dr. Hyman discusses vitamin D in relation to sun exposure patterns.
    • 7 Oct 2026 · Vitamin D · recommends · YouTube ↗
      States that vitamin D supplementation can help with oxidative stress.
    • 7 Oct 2026 · Vitamin C · neutral · Podcast ↗
      Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
    • 7 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Mentions topical vitamin C as an antioxidant that can help skin with aging.
  • Thomas DeLauer · Zinc · uses
    • 23 Oct 2026 · uses · YouTube ↗
      Adds zinc to their immunity duo because it helps them absorb vitamin C, considering the two together a fantastic combination for fall and winter.
    • 6 Nov 2026 · Vitamin C · recommends · YouTube ↗
      Recommends whole food vitamin C, found in kiwi fruit, citrus, and bell peppers, to help clear uric acid by competing at kidney transporters, preventing reabsorption.
    • 5 Nov 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking Vitamin D3 in the morning, between 6:00 and 10:00 a.m., to align with the body's natural metabolic activation phase and sunlight-triggered vitamin D production.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 23 Oct 2026 · Vitamin D · uses · YouTube ↗
      Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
    • 20 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking a massive amount of vitamin D simultaneously with an early morning massive breakfast to help reset circadian rhythms and address hyperphagia.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends zinc, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 8 Oct 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D, stating that it has receptors throughout the brain and deficiency can quickly impact brain and mood.
    • 6 Oct 2026 · Vitamin D · uses · YouTube ↗
      Takes supplemental vitamin D because he is skin sensitive and from northern latitudes, limiting his UV exposure.
    • 5 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking vitamin D on non-liver days to ensure both nutrients get proper receptor access.
    • 4 Oct 2026 · Selenium · recommends · YouTube ↗
      Recommends adding selenium to the diet, found in Brazil nuts (two or three a day), eggs, shellfish, and mushrooms, as the glutathione recycling process is very selenium dependent and it helps protect against feroptosis.
    • 4 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
    • 3 Oct 2026 · neutral · YouTube ↗
      Mentions that more zinc could be beneficial for testosterone, but it's not working on the axis that most people need help with.
  • Dave Asprey · Zinc · uses
    • 7 Oct 2026 · uses · YouTube ↗
      Developed a nonnano zinc sunscreen over five years, stating her skin is probably better now than it's ever been.
    • 3 Nov 2026 · Biotin · warns · YouTube ↗
      Mentions that most places put in extra biotin for hair growth, suggesting it's not always necessary or beneficial.
    • 3 Nov 2026 · Vitamin C · neutral · YouTube ↗
      Recounts a doctor telling him in his 20s that vitamin C would kill him.
    • 1 Nov 2026 · Vitamin D · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs.
    • 25 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Suggests that vitamin D supports brain health, muscle function, and focus.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 9 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
    • 7 Oct 2026 · Vitamin C · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 7 Oct 2026 · Vitamin D · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 7 Oct 2026 · Vitamin E · uses · YouTube ↗
      Dave Asprey's kids get a little bit of vitamin E every day, which helps to stabilize the bad oils they get when eating at restaurants.
    • 5 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Recommends vitamin D, noting it's actually a hormone and that most people are deficient, even those who take it, because they don't take enough.
    • 3 Sep 2026 · recommends · YouTube ↗
      Emphasizes the importance of having enough zinc before trying advanced longevity strategies like peptides.
    • 3 Sep 2026 · Selenium · recommends · YouTube ↗
      Emphasizes the importance of having enough selenium before trying advanced longevity strategies like peptides.
    • 3 Sep 2026 · Vitamin D · recommends · YouTube ↗
      States that most people on the spectrum are low in vitamin D and need more of it, mentioning his own product, Vitam DAKNE, which contains real vitamin A.
  • Siim Land · Selenium · recommends
    • 5 Aug 2026 · recommends · YouTube ↗
      States that deficiencies in nutrients such as selenium can impair normal immune regulation.
    • 31 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
    • 29 Oct 2026 · Vitamin D · recommends · Instagram ↗
      Recommends taking Vitamin D with fat for better absorption.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 24 Oct 2026 · Vitamin D · neutral · Instagram ↗
      States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 30 Sep 2026 · Vitamin C · neutral · X ↗
      Lists sauerkraut and fruit as sources of Vitamin C.
    • 30 Sep 2026 · Vitamin A · neutral · X ↗
      Lists liver and carrots as sources of Vitamin A.
    • 6 Sep 2026 · Vitamin D · recommends · Instagram ↗
      Thinks vitamin D has some of the strongest evidence and is worth considering.
    • 6 Sep 2026 · Vitamin D · neutral · X ↗
      Notes that Vitamin K2 pairs well with vitamin D by regulating calcium and bone mineralization.
    • 6 Sep 2026 · Vitamin C · neutral · X ↗
      Notes that Vitamin C is one of several supplements with human evidence.
    • 26 Aug 2026 · Vitamin D · recommends · Instagram ↗
      Recommends taking vitamin D supplements with some fat to maximize its absorption, suggesting with food or a teaspoon of olive oil.
    • 23 Aug 2026 · Vitamin D · neutral · X ↗
      Notes that taking vitamin D3 with a fat-containing meal resulted in 32% higher peak blood vitamin D levels.
    • 17 Aug 2026 · Vitamin D · recommends · X ↗
      Recommends taking Vitamin D in the morning or at lunch with fat.
  • Bryan Johnson · Zinc · uses
    • 4 May 2026 · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 22 Oct 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Aug 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 3 Jul 2026 · Vitamin D · neutral · X ↗
      Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
    • 4 May 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for longevity.
    • 2 May 2026 · Vitamin D · uses · X ↗
      He takes 5000 IU of Vitamin D3 in the morning for general health.
    • 21 Apr 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Apr 2026 · Vitamin D · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for longevity.
    • 14 Apr 2026 · uses · X ↗
      Takes 15 mg of Zinc in the morning.
    • 14 Apr 2026 · Vitamin D · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning.
    • 8 Apr 2026 · Vitamin D · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning.
    • 7 Apr 2026 · Vitamin D · uses · X ↗
      He takes 5000 IU of Vitamin D3 in the morning for general health.
    • 2 Apr 2026 · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 3 Feb 2025 · Vitamin C · neutral · YouTube ↗
      Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
  • Peter Attia · Zinc · recommends
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 4 Jan 2026 · Vitamin D · uses · YouTube ↗
      Lists vitamin D as one of her staple supplements.
    • 17 Nov 2025 · Iodine · warns · Podcast ↗
      Discusses the dangers of supplementing with high levels of iodine.
    • 16 Nov 2025 · Selenium · neutral · YouTube ↗
      Notes that several studies show patients taking selenium can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 16 Nov 2025 · Vitamin D · neutral · YouTube ↗
      Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 16 Nov 2025 · Iodine · warns · YouTube ↗
      Warns that high-dose iodine supplementation carries a risk of autoimmune thyroid disease, citing increased incidence in Japan due to higher dietary iodine intake.
    • 6 Aug 2025 · Vitamin D · neutral · YouTube ↗
      States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
    • 6 Aug 2025 · Vitamin A · neutral · YouTube ↗
      Notes that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin A for male mice.
    • 3 Aug 2025 · Vitamin D · neutral · YouTube ↗
      Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
    • 20 Jul 2025 · Vitamin D · neutral · YouTube ↗
      In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
    • 20 Jul 2025 · Vitamin A · neutral · YouTube ↗
      In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin A for male mice.
    • 10 Jul 2025 · Vitamin D · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.
    • 9 Jul 2025 · Vitamin D · recommends · YouTube ↗
      Recommends Vitamin D3 as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 800 to 1,000 IU, which can be obtained through sunlight or supplementation.
    • 6 Jul 2025 · Vitamin D · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might overcome the negative effects of phenytoin on bone health by counteracting increased catabolism of vitamin D and subsequent decreased calcium absorption.

RAL Summary

Members OnlyTier 2 for Thyroid Health

Full-dose selenium, backed by pooled trials in Hashimoto thyroiditis [1][2], and zinc with meds [4] show improvement in thyroid markers. Over 6,000 reviews are 70% positive, which supports tier 2.

Where the evidence disagrees: 106 of the 227 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Endocrine system, Immune system

Possible side effects: Too much iodine can enlarge the thyroid or slow its recovery, and one review reported more side effects with selenium. High biotin can distort thyroid blood test results, so tell your doctor before blood work.

Supplement Facts

Vitamin A 1500 mcg RAE · Vitamin C 60 mg · Vitamin D 62.5 mcg
Supplement Facts
Serving Size 4 Capsule(s)
Servings Per Container 30
Amount Per Serving% Daily Value
Vitamin A1,500 mcg RAE
Vitamin C60 mg
Vitamin D62.5 mcg
Vitamin E3.5 mg
Biotin3,000 mcg
Iodine226 mcg
Zinc25 mg
Selenium200 mcg
Synergen Complex1,720 mg†
Nutrafol Blend575 mg†
† Daily Value not established.

Other ingredients: Hypromellose, Rice Husk.

Label source: NIH label database · Report a label change

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Graded November 11, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.