Planetary Herbals Digestive Grape Bitters Review
Planetary Herbals Digestive Grape Bitters™ is a liquid herbal supplement marketed under the heading Supports Digestion. The page explains that herbal bitters have been an integral part of almost every herbal tradition in the world and are extensively used in Europe. According to the page, herbal bitters help enhance digestion and assimilation by stimulating taste receptors on the tongue. This increases the flow of bile from the liver, which the page says supports both digestion and the body's natural cleansing processes. The page notes that bitters are especially beneficial when taken after a heavy meal. The product provides three main classes of bitter herbs: tonic, warming, and aromatic bitters. The proprietary extract blend of 600 mg combines gentian root, angelica root, astragalus root, bai-zhu atractylodes rhizome, dill seed, juniper berry, Oregon grape root, yerba santa leaf, cardamom seed, ginger root, yarrow leaf and flower, coriander seed, and galangal rhizome, with essential oils of anise seed and orange peel. Suggested use is 1 teaspoon (approximately 5 mL) twice daily, taken half an hour before meals or after a heavy meal. Other ingredients are deionized water, grape juice concentrate, and grain alcohol at 20 to 30 percent by volume. The label warns not to use the product if pregnant, may become pregnant, or breastfeeding, unless under the direct supervision of a health care professional. Customers are told not to use the product if either tamper-evident seal is broken or missing, to keep it out of the reach of children, and to shake well before using. The page lists three sizes: 2 fl oz (SKU PF0137, $10.25), 4 fl oz (SKU PF0125, $18.98), and 8 fl oz (SKU PF0126, $36.50). The page states that Planetary Herbals does not sell directly to consumers and links to a where-to-buy page for retailers.
We don’t sell supplements. We help you make decisions and get the best price.
Lowest prices
We may earn a commission from some store links. How we choose.
We hold no current store prices for it yet: check the store.
Sold at: Planetary Herbals
Study, Trial or Testing Result Summary
Members OnlyHuman studies
No human studies were found that test this product or its herbs for easing upper stomach discomfort after meals, so there are no study findings to report here. The formula is a liquid bitters made from gentian root, angelica root, astragalus root, atractylodes, dill seed, juniper berry, Oregon grape root, yerba santa, cardamom, ginger, yarrow, coriander, galangal, and anise and orange peel oils. All of these sit inside one proprietary blend. The label does not give the amount of any single herb, so there is no way to tell whether any of them reaches a dose that has been studied. The tier rests on buyer ratings. About twenty-two thousand ratings are counted, and nearly all of them are positive. Only two short written reviews could be read. One praises the flavor and says it helps digestion move along. The other, after about a week of use, says it seems to help with heartburn. Treat these as early personal impressions, not proof that it brings fast relief. The product also contains grain alcohol, which matters for anyone avoiding alcohol. Animal and cell studies are never counted.
Review Totals and Summary
Members Only22,771 reviews · 98% positive
Across the stores, the Planetary Herbals Digestive Grape Bitters shows 22,764 ratings in total, but the themes below come from the written reviews that could be read on their pages, and only two written reviews were readable, both on Walmart. What buyers praise: Both written reviews are positive, though brief. One reviewer, who has a verified purchase, says the flavor is nice. The same reviewer says the bitters help increase digestive movement. The other reviewer says the product seems to be helping with heartburn. What buyers complain about: No complaints appear in the readable reviews. The page carries no negative comments about taste, effectiveness, value or anything else. Who it seems to suit: Going only by what the two reviewers describe, it appeals to people looking for digestive support, specifically those who want help with digestive movement or with heartburn. Neither reviewer says anything more about who they are or why they chose it. Taste, form and value: Flavor is the only taste point made, and it is favorable, with one reviewer calling it nice. Nobody comments on price, value for money, serving size, bottle size or how the liquid is taken. No other forms of the product (gummies, capsules, powder) showed up in the readable reviews, so there was nothing to leave out on that front. Caveats on the evidence: One reviewer had used the product for only about a week. That person says it seems to be helping with heartburn but is not yet sure of the long-term effect, so the heartburn comment is an early impression and not a settled verdict. With just two written reviews, both short, the sample is too small to draw firm conclusions. The large rating count suggests many more people have tried the product than have written about it, but those ratings come without any text, so they do not reveal what people liked or disliked. Overall, the readable feedback is warm but thin on detail: a pleasant flavor, a perceived boost to digestive movement, and a tentative sign of heartburn relief, with no criticism recorded. Anyone considering it should treat these as early, anecdotal impressions and not as proof of lasting results.
Biohacker Summary
Members Only7 of 10 recommend it
The panel has no statements about the main ingredient of this bitters blend, so what follows covers only the smaller ingredients. Astragalus drew the most comment, with seven of the ten speaking about it. Several of them take or recommend it as an adaptogen or immune support, one takes it only when run down in winter, and one warns it can overstimulate and that adaptogens should not be taken all the time. Gentian root, also a smaller ingredient in this product, was praised by two panelists, one for a subtle uplifting effect and one who used it with artichoke extract to get past reflux and heartburn and has not needed meds in about eight years. Dill was mentioned mostly as a cooking herb, and one panelist noted insufficient evidence for using it to treat period pain.
See all 7 biohackers →Hide the biohackers
Dr. Mark Hyman · Astragalus · uses
- Puts astragalus, a Japanese herb, into his chicken soup because it has a huge effect on the immune system and improves immune response.
- Recommends gentian root as an ingredient in Besper that adds a subtle uplifting effect.
- Notes that gentian root in Vesper adds a subtle uplifting effect.
- Uses fresh dill as an ingredient in a salmon recipe.
- Recommends astragalus for immune system issues and helping repair a leaky gut, noting it's a top herb in Chinese medicine and a great example of one that strengthens the body's system to fight off viruses.
- Recommends Astragalus as a great example of an herb that strengthens one's own system to better fight off a virus.
- Recommends astragalus for long-term prevention and strengthening of the immune system, noting its ability to help repair a leaky gut and support the gut-related immune system.
- Mentions astragalus as a helpful herb for immune support.
- Mentions that they will be doing deep dives into Astragalus as part of their ongoing discussions.
- Mentions that they can provide a supplement, an Astragalus root product, to increase telomere length.
Ben Greenfield · Astragalus · neutral
- Mentions Astragalus as one of the Chinese herbs used, noting its potential in decreasing the rate at which telomeres shorten.
- Stuffs the trout with herbs like dill.
- Considers astragalus a really good adaptogen to use with lunch to help with afternoon naps.
- Ben Greenfield uses Astragalus as an adaptogen to help him nap.
- Ben mentions reading up on a book while lying in bed at night with astragalus tincture as a resource for learning about plants.
- Mentions the herb astragalus as something that can help with the conversion of white fat to brown fat.
- Ben uses Astragalus for telomere length.
- Ben mentions Astragalus as a hack for travel.
- Travels with astragalus, specifically Kion Chi, for long-haul flights to help heal cells from radiation and for anti-aging.
- Lists Astragalus TA-65 as a compound recommended by Dr. Kaufmann for anti-aging.
- Lists Astragalus for telomeres.
- Ben recommends Gentian bitters for naturally increasing HCL production.
Dr. Eric Berg · Dill · neutral
- Notes that Wikipedia states there is insufficient evidence to recommend the use of dill for treating dysmenorrhea.
- Astragalus is a natural immunomodulator.
- Recommends choosing one or two herbs, including Astragalus, to help inhibit EBV from coming out of remission.
- Recommends Astragalus, a Chinese herb, to help put the Epstein-Barr virus back into remission.
- Mentions dill as a food high in quercetin.
- Identifies dill seeds as one of the worst seeds for keto due to their high net carbohydrate value.
- Recommends astragalus as an adrenal adaptogen that helps counter stress.
- Recommends astragalus, taking six grams of the dried root simmered in two cups of water for 30 minutes, once a day, as a potent antiviral remedy and for reducing stress to put the Epstein-Barr virus back in remission.
- Recommends taking Angelica Root as a potential solution for chronic fatigue, achiness, and stiffness.
- Recommends Angelica root as a natural a med with minimal side effects for addressing mycoplasma.
- Recommends astragalus as a potent herb that has been shown to decrease creatine and improve the filtration rate of the kidneys, helping to reverse kidney damage.
- Recommends astragalus as a potential thing to take to help support T helper cells.
- Recommends astragalus as an antiviral and anti-microbial to help with infections or chronic systemic immune weakness.
- Mentions that astragalus has the ability to boost telomerase and has interesting anti-aging properties, increasing the immune system, decreasing sickness, improving sleep, and increasing memory, but studies are inconclusive regarding life extension.
Siim Land · Astragalus · warns
- Warns that Astragalus Root can inhibit the COMT or MAO genes, effectively 'plugging the drain' for adrenaline and leading to overstimulation, and is often found in thyroid supplements.
- States that astragalus is the source of ingredients like those in TA-65 and 818, and consuming it on a regular basis is not a bad idea for telomere health.
- Highlights astragalus as a significant longevity herb, with one of its main roles being immune modulation.
- Biohacked his way out of reflux and heartburn using gentian root and artichoke extract, and hasn't needed reflux medications for about eight years.
Thomas DeLauer · Astragalus · uses
- Takes Astragalus during the winter time, not regularly, but when he feels run down, as he finds adaptogens work best when taken only when needed to help regulate the body.
- Used to take Astragalus for recovery and immune function but now warns that adaptogens like Astragalus should not be taken all the time, as they could potentially 'trap' one in a perpetual state of issues if taken when feeling run down.
- Mentions Angelica root extract but states he needs to do more research on it as he doesn't know much about it.
- Recommends using a little bit of dill weed with breakfast, keeping spices simple during the carnivore challenge.
- Uses Dill Sheety, an apple nectar, as a sugar substitute, noting its extremely low glycemic index (7-9) and that it's derived from organic apples.
Dave Asprey · Astragalus · neutral
- Mentions that astragalus is used in some of their products, noting that in huge amounts it is a very advanced telomere lengthening supplement, and at lower doses, it is a well-known adaptogen.
- Mentions that astragalus is added to Flying Embers products during fermentation and acts as an adaptogen to help turn stress responses on and off more effectively.
- Discusses Astragalus as an adaptogen for stress and sex.
- Lists astragalus as an ingredient in Mighty Gum, which is recommended for hacking biology.
Dr. Rhonda Patrick · Astragalus · neutral
- Extracts of the astragalus root, the key ingredient in the dietary supplement TA-65, promoted telomerase activity and increased telomere length as much as 40 percent in humans.
RAL Summary
Members OnlyTier 3 for After-Meal Comfort: Fast Relief
Rated tier 3 on reviews: 98% of about 22,771 ratings are positive, but no human studies on this goal were found for its ingredients, so study support is thin.
- No human studies on this goal for its ingredients.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Digestive system
Combine with: For digestive support, pair the bitters with a broad-spectrum digestive enzyme blend, ginger root, or peppermint to ease occasional fullness and gas. Artichoke leaf or milk thistle can complement the bitter-stimulated bile flow and liver support, and a probiotic can support gut balance. If the real goal is cellular and DNA repair, use dedicated compounds instead: NAD+ precursors (NMN or nicotinamide riboside), resveratrol or pterostilbene, quercetin with fisetin, CoQ10 or ubiquinol, alpha-lipoic acid, and omega-3s, along with magnesium and B vitamins. Check with a clinician first, especially if you take medications or have gallbladder disease, ulcers or reflux, since bitters can increase acid and bile secretion.
Possible side effects: No major side effects reported. The liquid contains 20 to 30 percent grain alcohol by volume.
Supplement Facts
Proprietary Extract Blend 5 mL
| Proprietary Extract Blend | 5 mL | † |
Other ingredients: Purified Water, Grape juice concentrate, Grain Alcohol.
Directions: Suggested Use: 1 teaspoon twice daily. Take 1/2 hour before meals, or after a heavy meal. Shake well before using.
Barcode (UPC) 021078101260 · Label source: NIH label database · Report a label change
Other sizes and barcodes: 2 fl. Oz.; 59.14 mL, UPC 0 21078 10137 6 (not checked yet); 4 fl. Oz.; 118.28 mL, UPC 0 21078 10125 3 (not checked yet)
Show entire label
More after-meal comfort: fast relief products
Members OnlyThe highest ranked for the same goal
Graded November 10, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
Privacy policyConsumer health dataAffiliate disclosureTermsDo Not Sell or Share My Personal InformationCookie settings