Pure TheraPro Rx Bio Boron 30 mg Review

Pure TheraPro Rx Bio Boron is a 30 mg boron supplement in capsule form, sold as a 90 count bottle of Bororganic Glycine Boron supplements for men and women. The product page states that boron can be challenging for the body to absorb, and that this formula contains Albion's Bororganic Glycinate, which the brand says optimizes absorption and bioavailability. The page describes boron as an essential nutrient for optimal health and says the supplement supports bone metabolism, immunity, and nervous system health. The listing highlights several areas of support. It says boron acts as a Vitamin D and Magnesium cofactor and assists in the absorption and utilization of Calcium, and it mentions Calcium, Magnesium and Phosphorus, activation of Vitamin D, and healthy aging. The page also claims that boron has been shown to support healthy hormonal balance, brain activity, and cell membrane function. For bones, it refers to strong bones, healthy bone growth and mineralization, and support for the bone matrix's connective structure, including ligaments and tendons. For cognition, it refers to maintaining the proper function of cell membranes and supporting brain and cognitive function. Each capsule contains 30 mg of Boron, and the page says this helps maintain healthy hormone activity, with boron described as aiding the production, regulation, and half-life of hormones and helping protect hormones from rapid breakdown. The About Us section states that Pure TheraPro Rx was founded in Denver, Colorado, to formulate and manufacture supplements. The brand says purity is its priority, that it uses patented, clinically studied ingredients, and that it does not use fillers, flow agents, excipients, or ingredients sourced from China. It also states that its formulas do not contain dairy, gluten, corn, soy, or other common allergens, and describes them as practitioner-recommended. The page lists a current price of USD $29.97, sold by Pure TheraPro and fulfilled by Walmart, with a free 90-day return policy. The product details, specifications, indications, directions, warranty and ingredients sections are present as headings but show no content in the scraped text, so dosing directions, full ingredient list and specifications cannot be confirmed from this page.

Product Focus: Bone Health
Tier ⓘ
Tier 4
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
56 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
100% of 113
Biohacker Mentions
6 of 10

Study, Trial or Testing Result Summary

Members Only6 human studies · 4 improved
6 human studies4 improved401 people studied

The evidence that swallowed boron helps bone health is limited. This product gives 30 milligrams of boron a day, far above the 250 micrograms used in the main bone study. In an open study of 334 women past menopause with low bone density, a daily mineral tablet with 250 micrograms of boron plus calcium, vitamin D and other minerals raised spine bone density by about 1.5% over a year while the comparison group lost bone. Because the tablet held many ingredients and there was no placebo, the gain cannot be credited to boron [1]. In a one-year controlled trial of 28 young women, boron changed blood phosphorus and magnesium but showed no clear bone benefit [2][3]. Boric acid gel placed into gum pockets during deep cleaning improved jawbone defects compared with placebo gel, by about 37% versus 3% in one trial [4] and 17% versus 3% bone fill in another [5], and a review of eight gum studies agreed [6]. These gum results come from local treatment of gum disease, not from swallowing a supplement, so they say little about this product. Animal and cell studies are never counted.

See all 6 studies →Hide the studies

Review Totals and Summary

Members Only113 reviews · 100% positive
113 reviews · Purethera 111 · Walmart 2
100% positive0% neutral0% negative

Customer feedback for Pure TheraPro Rx Bio Boron 30 mg highlights several qualitative themes, with many users expressing significant satisfaction, particularly regarding its impact on bone health. A recurring sentiment among long-term users, especially those previously diagnosed with osteoporosis, is the remarkable improvement in bone density. Several individuals reported a noticeable increase in bone density, with one user even experiencing a 20 percent increase in some areas after five years of consistent use, leading them to become a "lifelong believer". These testimonials often emphasize that while results may not be immediate, patience is key to experiencing these profound benefits. Beyond bone health, customers frequently praise the supplement for contributing to a general sense of well-being and sustained energy. Some users have noted feeling a "more steady all day energy" that they hadn't experienced in a long time, even when starting with a reduced dosage due to sensitivity. The product's high bioavailability, attributed to Albion's Bororganic Glycinate, is often implicitly or explicitly appreciated by customers who report feeling a tangible difference in their bodies. However, a notable qualitative theme in customer feedback revolves around initial "detox symptoms." Several users, particularly those new to boron supplementation, have reported experiencing mild side effects such as headaches, fatigue, or brain fog when first starting the supplement. This feedback often includes advice to begin with a lower dose, sometimes as little as a quarter capsule, and gradually increase it as the body adjusts to mitigate these temporary effects. Despite these initial adjustments, the overall sentiment remains positive, with many customers finding the product easy to incorporate into their daily routine once the appropriate dosage is established. The consistent positive outcomes, especially in areas like bone density, have cultivated a loyal customer base, with many considering themselves "lifelong customers" due to the perceived effectiveness of the product.

Biohacker Summary

Members Only6 of 10 recommend it
6 of 10 biohackers on our panel recommend it

Boron is the only ingredient here, and the panel leans toward it: of the ten, six recommend it in their latest statements, one uses it, and three stay neutral. The most common reason is hormones, as several say it lowers a binding protein called SHBG, which frees up more testosterone without raising total testosterone. Others take it for bone strength, for helping vitamin D work, and for longevity. Doses they name run from 2 mg up to 12 mg a day, with 6 to 12 mg the most common range, and one panelist describes his own low dose. Panelists pair it with vitamin D, K2, magnesium and zinc, and one says to try it if SHBG is high; one panelist notes that people should look at possible side effects, and another calls it a safe choice.

See all 9 biohackers →Hide the biohackers
  • Siim Land · Boron · neutral
    • 8 Oct 2026 · neutral · Instagram ↗
      Boron is a mineral that helps with bone density and vitamin D utilization, and also helps to increase free testosterone by reducing SHBG.
    • 3 Oct 2026 · neutral · Instagram ↗
      States that boron is a superstar when it comes to hormone and bone optimization.
    • 18 Aug 2026 · neutral · X ↗
      Notes that prunes are the highest food source of boron.
    • 14 Aug 2026 · neutral · X ↗
      Prunes are an excellent source of boron, providing 1.5 to 3.0 mg of boron per 3 oz serving.
    • 14 Aug 2026 · recommends · X ↗
      Recommends Boron, calling it a "superhero mineral" that helps bone mineralization, improves vitamin D, improves testosterone/estrogen status, increases antioxidant defense, reduces inflammation, and reduces calcium/magnesium loss.
    • 12 Jun 2026 · stopped · YouTube ↗
      Notes that Boron improves bone mineral density by improving vitamin D status and lowering inflammation, and increases testosterone and estrogen by reducing SHBG, but he stopped taking it as it didn't increase his testosterone or lower his SHBG, and it only works in particular conditions like high SHBG.
    • 5 Jun 2026 · neutral · Instagram ↗
      Notes that Boron helps to lower SHBG but only to a certain degree.
    • 23 Feb 2026 · recommends · Instagram ↗
      Recommends boron as a bonus to pair with a vitamin D supplement.
    • 28 Dec 2025 · recommends · YouTube ↗
      Recommends boron, stating it's a mineral that helps with testosterone by lowering SHBG levels and also aids bone density, noting that many people are deficient.
    • 5 Nov 2025 · recommends · YouTube ↗
      Recommends taking boron whenever taking vitamin D supplements to increase vitamin D utilization.
  • Dr. Eric Berg · Boron · neutral
    • 2 Oct 2026 · neutral · YouTube ↗
      States that boron, along with other trace minerals, is necessary for bone formation and that K2 helps direct these minerals into the bone.
    • 6 Jun 2026 · neutral · Instagram ↗
      States that Vitamin D needs K2, magnesium, zinc, B6, boron, and even vitamin A to do its job, emphasizing that vitamins rarely work alone.
    • 22 Jun 2024 · recommends · Podcast ↗
      Recommends getting plenty of boron when taking vitamin D.
    • 22 Jun 2024 · recommends · YouTube ↗
      Mentions that boron is a crucial nutrient needed for vitamin D to go through its biochemical reactions and maximize its effectiveness.
    • 24 May 2024 · recommends · Podcast ↗
      Recommends taking boron as a cofactor when taking vitamin D to help shrink fibroids, suggesting the recommended dose on the bottle.
    • 9 May 2024 · recommends · Podcast ↗
      Recommends ensuring adequate boron intake when taking vitamin D supplements.
    • 8 May 2024 · recommends · Podcast ↗
      States that boron may help prevent calcification of the soft tissues.
    • 25 Apr 2024 · recommends · Podcast ↗
      Recommends starting with 3 mg of boron three times per day to help relieve arthritis symptoms, noting that it helps keep minerals inside the bone, allows vitamin D to be activated, and helps prevent tooth decay.
    • 2 Apr 2024 · neutral · Podcast ↗
      Includes Boron as a natural alternative to increase vitamin D levels and combat vitamin D resistance.
    • 31 Mar 2024 · recommends · YouTube ↗
      States that boron helps override the problem of vitamin D receptor resistance.
  • Ben Greenfield · Boron · recommends
    • 7 Jun 2026 · recommends · Facebook ↗
      Recommends using hormone building blocks like boron for hormone optimization.
    • 19 Apr 2025 · recommends · YouTube ↗
      Recommends consuming boron as a building block for testosterone.
    • 5 Apr 2025 · recommends · YouTube ↗
      Recommends boron as one of the foundational supplements to consider before TRT for testosterone support.
    • 3 Apr 2025 · recommends · YouTube ↗
      Recommends boron as an important precursor for testosterone.
    • 21 Mar 2025 · recommends · YouTube ↗
      States that boron is important for naturally increasing testosterone.
    • 13 Feb 2025 · recommends · YouTube ↗
      Recommends checking boron levels and ensuring adequate intake if testosterone is low.
    • 17 Aug 2024 · uses · YouTube ↗
      Uses Boron, which he knows anecdotally helps with testosterone, but his cardiologist recommended it for heart health.
    • 11 Apr 2024 · warns · YouTube ↗
      Warns of boron deficiency on a strict carnivore diet, as it is not found in many meats or organ meats, and low intake has been linked to issues with bone health, brain health, and hormone production.
    • 19 Nov 2022 · recommends · YouTube ↗
      Recommends ensuring adequate boron intake as a foundational element before considering testosterone therapy for issues like poor libido or decreased performance.
    • 27 Feb 2020 · uses · YouTube ↗
      States he gets boron from bone broth.
  • Dave Asprey · Boron · neutral
    • 27 May 2026 · neutral · YouTube ↗
      Lists boron as one of the minerals needed.
    • Date not recorded · uses · Website ↗
      Mentions using boron.
  • Bryan Johnson · Boron · uses
    • 4 May 2026 · uses · X ↗
      Takes 2 mg of Boron in the morning for longevity.
    • 14 Apr 2026 · uses · X ↗
      Takes 6 mg of Boron in the morning.
    • 2 Apr 2026 · uses · X ↗
      Takes 6 mg of Boron in the morning for longevity.
    • 5 Jun 2025 · recommends · YouTube ↗
      Recommends boron as a mineral that, along with calcium, phosphorus, and magnesium, is deposited to fortify the bone structure.
    • 7 Dec 2023 · neutral · Instagram ↗
      Mentions boron as a potential therapy that could positively influence sperm health.
  • Dr. Rhonda Patrick · Boron · recommends
    • 17 Dec 2025 · recommends · Instagram ↗
      Recommends Boron, stating it potentially reduces SHBG levels, freeing up bound testosterone, and is particularly useful at dosages around 6-12 mg daily.
    • 15 Sep 2025 · neutral · Facebook ↗
      Boron may play a supportive role for optimizing testosterone. Supplementing with 6-12 mg per day can increase free testosterone by suppressing SHBG.
    • 14 Sep 2025 · neutral · Facebook ↗
      Supplementing with boron may boost free testosterone by lowering sex hormone-binding globulin (SHBG). While boron won’t increase total testosterone production, doses around 6 to 12 mg daily may help free up more testosterone by modestly reducing SHBG levels.
    • 9 Sep 2025 · recommends · YouTube ↗
      Suggests Boron as a safer choice for boosting testosterone due to its safety profile, and notes that it has also been thought to potentially be a longevity molecule.
    • 12 Jun 2024 · uses · YouTube ↗
      Takes a low dose of boron.
    • Date not recorded · uses · Website ↗
      She occasionally uses boron, meaning about twice a week.
  • Dr. Mark Hyman · Boron · recommends
    • 12 Mar 2025 · recommends · YouTube ↗
      Recommends taking Boron if you have high sex hormone binding globulin (SHBG) to lower it and increase free testosterone.
    • 16 Sep 2022 · neutral · YouTube ↗
      Mentions that sometimes antifungal medications like boronox are needed for fungal overgrowth.
    • 15 Jun 2022 · recommends · YouTube ↗
      Lists boron as a critical nutrient for building strong bones.
    • 7 Nov 2021 · neutral · YouTube ↗
      Mentions that boron is needed for bone formation.
    • 13 May 2021 · recommends · YouTube ↗
      States that most people will still be lacking boron because it is very difficult to source in the diet, making it a great supplement to take.
    • 4 Jan 2021 · recommends · YouTube ↗
      Mentions there is some evidence that boron can be helpful for osteoporosis.
    • Date not recorded · neutral · Website ↗
      Lists Boron Glycinate: 2 mg by Pure Encapsulations as a product available.
  • Thomas DeLauer · Boron · recommends
    • 8 Feb 2025 · recommends · YouTube ↗
      Recommends boron for helping with sex hormone binding globulin decreases, leading to more free androgens and potentially balancing estrogen.
    • 3 Jan 2024 · uses · YouTube ↗
      Uses a mix of magnesium, zinc, and boron, along with Tongkat Ali and Forskolii, to support testosterone levels and increase libido, especially during prolonged deficits.
    • 1 Dec 2019 · recommends · YouTube ↗
      Recommends that men try supplementing with 9 milligrams of boron to help release testosterone in the form of free testosterone by unbinding it from sex hormone-binding globulin.
    • 28 Aug 2019 · recommends · YouTube ↗
      Recommends that males experiment with taking boron, possibly 9 milligrams, as it has been shown to unbind testosterone from sex hormone binding globulin, helping to balance estrogen and androgen levels.
    • 14 Jul 2019 · recommends · YouTube ↗
      Recommends boron, stating it doesn't increase total testosterone but unlocks bound testosterone to be free, with studies showing a significant increase in available free testosterone after one week of 10 milligrams daily.
    • 30 Jun 2019 · recommends · YouTube ↗
      Recommends boron for males to unlock bound-up testosterone, leading to more muscle mass, energy, strength, and libido.
    • 9 Jun 2019 · recommends · YouTube ↗
      Recommends consuming small amounts of boron, specifically six to nine milligrams a day, as studies have shown it can increase free testosterone levels.
    • 18 Jul 2018 · recommends · YouTube ↗
      Recommends boron, noting that it helps the kidneys retain magnesium and sustains the half-life of vitamin D, which prevents fluctuations that can be hard on the body and helps avoid vitamin D deficiency.
    • 5 Jan 2017 · recommends · YouTube ↗
      Recommends taking between 6 and 15 milligrams of boron daily to get the most impact, as studies show it increases free testosterone and decreases sex hormone binding globulin.
  • Andrew Huberman · Boron · recommends
    • 12 Dec 2022 · recommends · YouTube ↗
      Recommends boron, at a dose of 5 to 12 milligrams per day, to acutely help lower high SHBG, noting that it's depleted in soils in many countries.
    • 11 Apr 2022 · recommends · YouTube ↗
      Explains that boron, an element found in rich soils, can help regulate SHBG, and is unlikely to have a bad effect, suggesting a dose of 3 to 6 milligrams once to twice a day.
    • 12 Apr 2021 · neutral · Podcast ↗
      Discusses boron in relation to nettles, the prostate, and the blood brain barrier.
    • 12 Apr 2021 · neutral · YouTube ↗
      Notes that there is scientific support for boron freeing up more testosterone, with people typically taking a couple grams a day, and encourages examining potential side effects.
    • Date not recorded · uses · Website ↗
      Andrew Huberman has long been taking boron, at two to four milligrams per day, as part of a cocktail for testosterone augmentation.
    • Date not recorded · recommends · Website ↗
      Andrew Huberman recommends boron in a dose of 5 to 12 milligrams per day to acutely help lower very high SHBG, though it's not a sustained effect.

RAL Summary

Members OnlyTier 4 for Bone Health

The tier rests on two trials of boric acid gel placed into gum pockets during dental cleaning, a local gum treatment rather than a swallowed boron supplement, and the swallowed boron studies do not show a clear bone benefit from boron itself. So it is graded Tier 4, lower than the rules alone gave.

  • Emerging: not enough evidence to rank higher yet.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Skeletal system

Combine with: To enhance the benefits of boron, particularly for bone health, consider combining it with Vitamin D3 and Vitamin K2, which are crucial for calcium absorption and proper utilization in bones. Magnesium is also highly synergistic, as it works closely with boron and calcium for optimal bone mineralization and overall skeletal integrity. For broader support of hormonal balance, which boron can indirectly influence, zinc and healthy fats (like omega-3s) could also be beneficial additions.

Possible side effects: No major side effects reported in the studies; no written reviews could be read to confirm the headaches, tiredness or brain fog described in the review summary.

Supplement Facts

Boron 30 mg
Supplement Facts
Serving Size 1 Capsule(s)
Servings Per Container 90
Amount Per Serving% Daily Value
Boron30 mg†
† Daily Value not established.

Other ingredients: Hypromellose.

Directions: Directions: Take one (1) capsule daily, or as directed by a healthcare practitioner.

Label source: NIH label database · Report a label change

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Graded November 3, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.