Qunol Magnesium 420mg, Extra Strength, High Absorption, Vegetarian, 180ct Review

Qunol Magnesium Extra Strength 420 mg is a once-daily dietary supplement expertly formulated to support nerve, bone, muscle, and heart health. Nearly half of Americans (48%, according to an analysis of NHANES 2013-2016 data) do not ingest enough magnesium from food and beverages alone to meet their nutritional needs. To help bridge this nutritional gap, each two-capsule serving of Qunol Magnesium Extra Strength delivers 420 mg of magnesium, providing 100% of the recommended Daily Value in two convenient capsules. The formula is specifically focused on superior absorption, utilizing buffered chelated magnesium glycinate, which offers high absorption compared to regular magnesium composed of 100% magnesium oxide, and provides extra strength potency compared to Qunol Magnesium 200 mg Gummies. As an essential mineral backed by the trusted medical science of Qunol, this high-absorption supplement promotes healthy nerve, bone, and muscle function, while also helping to support muscle relaxation and a healthy response to occasional stress. For daily use, adults are instructed to take two capsules daily, or as recommended by a healthcare professional. The displayed 120-count bottle (with a 180-count option also listed on the page) contains 60 servings per container. In addition to its active ingredient of 420 mg buffered chelated magnesium glycinate, the product is made with a vegetarian hydroxypropyl methylcellulose capsule, silicon dioxide, and magnesium stearate. It is thoughtfully crafted to accommodate dietary restrictions and preferences: the formula is completely gluten-free, vegetarian, made without animal-derived ingredients, and formulated without synthetic dyes. Furthermore, it is free of major food allergens, including milk, egg, fish, shellfish, wheat, peanuts, and their by-products.

Product Focus: Regularity: Fast ReliefAlso covers:Digestion
Tier ⓘ
Tier 3
Tier 3 · Reviewed. Strong review agreement, with limited or early support from human studies. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
67 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
92% of 15,009
Biohacker Mentions
6 of 10
Cost per month
$9

Study, Trial or Testing Result Summary

Members Only35 human studies · 23 improved
35 human studies23 improved9 no effect4,329 people studied

This product provides 420 milligrams of magnesium as buffered chelated magnesium glycinate, which is below the 800 milligrams daily dose that worked in studies for constipation relief. Human trials mainly tested magnesium oxide and magnesium sulfate rather than magnesium glycinate. A 2023 pooled analysis of 8 trials with 787 adults found that 68 percent responded to magnesium oxide compared to 19 percent on control, gaining about 3.7 more bowel movements per week and softer stools [1]. In a 2021 controlled trial of 90 adults, 1.5 grams of magnesium oxide daily for 4 weeks improved symptoms in 68.3 percent of users versus 11.7 percent on placebo [2]. Drinking 1 liter daily of mineral water rich in magnesium and sulfate also helped adults in two trials, improving response rates to 50 percent versus 29 percent over 2 weeks in 226 people [3], and reducing constipation in 37.5 percent of 244 women versus 21.1 percent on low-mineral water [4]. In children, oral magnesium sulfate improved constipation in 68 percent versus 9.5 percent on placebo [5], and magnesium oxide for 4 weeks gave more bowel movements and softer stools [6]. Overall evidence for magnesium is rated as moderate. Animal and cell studies are never counted.

See all 35 studies →Hide the studies

Review Totals and Summary

Members Only15,009 reviews · 92% positive
15,009 reviews · Amazon 10,232 · Walmart 4,491 · Costco 154 · Qunol 130 · Fry's Food Stores 1 · Kroger 1
92% positive3% neutral5% negative

This Qunol Magnesium 420mg supplement has garnered significant attention, accumulating about 15009 ratings across various stores. The overall sentiment is largely positive, with 68% of reviews giving it 4 or 5 stars, indicating many users find it beneficial. **What buyers say it did for them** Many customers report positive effects from taking this magnesium supplement. Users frequently mention improvements in relaxation and sleep, with one reviewer stating it "helps tremendously with relaxation and sleep." Others found relief from physical discomfort, noting it "helps my body pain" and is effective for "relieving muscle cramps!" Some experienced benefits for restless legs and heart health. Several users who switched from other magnesium forms or brands found Qunol to be more effective, with one saying it's "the only one that works." **What they complain about** A notable number of complaints revolve around product formulation and transparency. Some customers expressed concern that the product's formulation changed, with one reviewer stating the company "changed the packaging and the formulation very sneakily." Several users discovered the product is "buffered," meaning it's mixed with cheaper, less bioavailable forms like magnesium oxide or citrate, which can lead to side effects such as "diarrhea for three weeks" and "stomach distress." Some felt this was deceptive, especially when expecting pure magnesium glycinate. Other complaints included delivery issues, receiving the wrong item, or damaged bottles. **Taste, smell, pill size, or form** Regarding the physical attributes of the supplement, many users find the pills easy to consume. One reviewer noted, "They’re easy to take. They’re not big." However, there were complaints from vegan customers who stated the "capsules were changed to gelatin," making the product no longer suitable for their dietary needs despite being advertised as vegetarian. **Value for money** Opinions on value are mixed. Some customers consider it an excellent deal, calling it the "best product at the best price." Conversely, others, particularly those who discovered the "buffered" formulation, felt the "Price is too good to be true," implying the lower cost comes at the expense of quality or purity due to fillers. **Who it seems to suit and who it did not** This supplement appears to suit individuals seeking general relaxation, improved sleep, and relief from muscle cramps or restless legs. It's often favored by those who have not found success with other magnesium forms, particularly magnesium oxide, and are looking for better absorption. However, it may not be suitable for those with sensitive digestive systems prone to diarrhea or stomach distress from magnesium oxide. It also did not suit migraine sufferers who found it ineffective due to the buffered formulation. Vegans should be aware of the reported change to gelatin capsules. Those expecting a pure magnesium glycinate product without fillers may be disappointed.

Biohacker Summary

Members Only6 of 10 recommend it
6 of 10 biohackers on our panel recommend it

Most of the panel recommends or uses magnesium, and sleep is the main reason, with five of the ten naming it directly, while others cite blood pressure, stress, muscle recovery, brain function and bone health. Forms matter to them: glycinate is favored by three for calming and sleep, and threonate by four, who take 400 mg before bed. Others suggest 300 mg before bed, 400 to 500 mg a day as a general need, or 300 to 500 mg a day as a minimum, and several take it in the evening or 90 minutes to 2 hours before bedtime. A few pair it with electrolytes like sodium and potassium, and one pairs it with glycine. One panelist cautions that labels can mislead by listing the whole compound weight instead of the actual magnesium, and says the evidence that it reliably improves sleep is inconsistent.

See all 10 biohackers →Hide the biohackers
  • Dr. Rhonda Patrick · Magnesium · recommends
    • 8 Nov 2026 · recommends · Instagram ↗
      Explains that magnesium helps the body activate and metabolize vitamin D, and that magnesium intake has been associated with lower odds of vitamin D deficiency and insufficiency.
    • 6 Nov 2026 · neutral · Instagram ↗
      Mentions that getting too little magnesium may play a role in declining testosterone levels.
    • 3 Nov 2026 · recommends · X ↗
      Recommends getting enough magnesium, around 300–400 mg daily from diet and supplements, as it is an essential cofactor for vitamin D metabolism. Magnesium glycinate is a good form.
    • 1 Nov 2026 · neutral · YouTube ↗
      Mentions magnesium as one of the micronutrients found in multivitamins that people often don't get enough of from their diets.
    • 31 Oct 2026 · neutral · YouTube ↗
      Explains that magnesium helps control blood pressure by boosting the production of substances that relax blood vessels and improve cardiovascular health, citing a meta-analysis that found magnesium supplementation at an average dose of 368 mg per day notably lowers both systolic and diastolic blood pressure.
    • 29 Oct 2026 · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 16 Oct 2026 · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 29 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 28 Sep 2026 · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 2 Sep 2026 · neutral · Facebook ↗
      States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
  • Dr. Eric Berg · Magnesium · recommends
    • 7 Nov 2026 · recommends · Facebook ↗
      Recommends Magnesium glycinate, noting its high absorption rate compared to magnesium oxide, and its support for energy, sleep, muscle relaxation, and vitamin D function.
    • 7 Nov 2026 · neutral · Instagram ↗
      Dr. Berg states that when nutrients like magnesium are too low, fatigue and weakness can follow.
    • 6 Nov 2026 · recommends · Podcast ↗
      Recommends focusing on magnesium to support stronger bones if a neck hump is associated with osteoporosis.
    • 6 Nov 2026 · neutral · Instagram ↗
      Explains that leg and calf cramps are most often caused by low magnesium, with leafy greens being a top source.
    • 6 Nov 2026 · recommends · YouTube ↗
      States that magnesium is a cofactor that allows B1 to work more efficiently.
    • 4 Nov 2026 · recommends · YouTube ↗
      States that magnesium is the most important mineral for energy production, as one cannot make energy without it.
    • 1 Nov 2026 · neutral · YouTube ↗
      Magnesium is involved in 300 to 600 enzyme reactions, acts as a biological brake pedal, is the master controller over calcium, and is involved in making ATP, the energy currency of the body. It takes energy to go to sleep, and magnesium is required for relaxation and good sleep. Magnesium also helps balance cortisol levels and calm you.
    • 30 Oct 2026 · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 28 Oct 2026 · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 25 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
  • Thomas DeLauer · Magnesium · recommends
    • 5 Nov 2026 · recommends · YouTube ↗
      Recommends taking magnesium glycinate and threonate at night to act as a brake on the nervous system, block excitatory signaling, help wind down, and support serotonin and melatonin production for better sleep.
    • 4 Nov 2026 · neutral · YouTube ↗
      Mentions that magnesium glycinate also helps a lot with sleep.
    • 2 Nov 2026 · neutral · YouTube ↗
      Mentions that restless leg syndrome is often treated with magnesium, but states that the sensation is actually coming from three other issues.
    • 28 Oct 2026 · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 24 Oct 2026 · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 6 Oct 2026 · neutral · YouTube ↗
      Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
    • 1 Oct 2026 · recommends · YouTube ↗
      Recommends taking some magnesium glycinate tonight to help calm down and sleep.
    • 25 Sep 2026 · neutral · Facebook ↗
      Mentions that magnesium in pumpkin seeds relaxes bronchial smooth muscle.
  • Andrew Huberman · Magnesium · recommends
    • 4 Nov 2026 · recommends · Instagram ↗
      Notes that Les Spellman's team includes 'Magnesium timed right' as part of their game plan to optimize recovery in unfavorable conditions.
    • 22 Oct 2026 · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 7 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 27 Jul 2026 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 20 Jul 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 20 Jul 2026 · recommends · YouTube ↗
      Confirms that magnesium is absolutely important for cognitive function, noting studies show those with lower magnesium intakes tend to perform less well on cognitive function tests, and it's related to brain changes over time and dementia risk.
    • 13 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 12 Jul 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate from Double Wood before bed for sleep.
    • 6 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 22 Jun 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
  • Dr. Mark Hyman · Magnesium · recommends
    • 4 Nov 2026 · recommends · YouTube ↗
      Recommends magnesium breakthrough advanced ten from Biooptimizers, which is their most complete magnesium formula with 10 bioavailable forms and 550 milligrams of elemental magnesium, designed to support restful restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 1 Nov 2026 · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 29 Oct 2026 · neutral · YouTube ↗
      Explains that a lack of magnesium can cause muscles and nerves to malfunction, resulting in muscle weakness, twitching, and cramps.
    • 21 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 14 Oct 2026 · recommends · TikTok ↗
      Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
    • 7 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 30 Sep 2026 · uses · YouTube ↗
      Has recommended magnesium breakthrough from bioptimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
    • 22 Sep 2026 · recommends · Instagram ↗
      Recommends correcting nutrient deficiencies with magnesium.
    • 16 Sep 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advance 10 from BiOptimizers, which has 10 bioavailable forms of magnesium and more elemental magnesium, as part of his evening routine for sleep, muscle recovery, and metabolic health.
  • Dave Asprey · Magnesium · uses
    • 3 Nov 2026 · uses · Instagram ↗
      Looks at magnesium alongside protein to keep muscle for the long run.
    • 3 Nov 2026 · recommends · YouTube ↗
      Suggests adding magnesium to help keep potassium in the system longer, as they work hand in hand.
    • 31 Oct 2026 · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 17 Oct 2026 · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 27 Sep 2026 · recommends · Podcast ↗
      Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
    • 7 Sep 2026 · uses · Instagram ↗
      Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
    • 5 Sep 2026 · recommends · YouTube ↗
      Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
    • 3 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
    • 29 Aug 2026 · recommends · YouTube ↗
      Dave Asprey recommends Magnesium Glycinate for sleep, noting human studies show it helps people fall asleep faster, is safe, and works on a fundamental aspect of health, unlike magnesium oxide which acts as a laxative.
  • Ben Greenfield · Magnesium · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 22 Oct 2026 · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 3 Sep 2026 · recommends · YouTube ↗
      Recommends supplementing with magnesium threonate if one is low in magnesium, as it crosses the blood-brain barrier and is demonstrated to increase hippocampus plasticity, theoretically making one smarter and improving memories.
    • 25 Aug 2026 · uses · Facebook ↗
      Uses Magnesium Breakthrough from BIOptimizers as part of their daily stack, taking four capsules in the evening to support relaxation, recovery, and a good night of sleep.
    • 17 Aug 2026 · recommends · Facebook ↗
      Recommends Celtic Sea Salt's new electrolyte drink "Hydrate" for replacing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, plus magnesium, taurine, and potassium.
    • 15 Aug 2026 · warns · YouTube ↗
      Had heart palpitations when he was really overdoing magnesium, not knowing what he was taking.
    • 8 Aug 2026 · recommends · YouTube ↗
      Recommends taking magnesium as a co-factor to increase vitamin D absorption.
    • 13 Jun 2026 · neutral · X ↗
      Notes a new study indicating that magnesium is a core dietary antioxidant closely associated with a reduced risk of accelerated biological aging.
  • Siim Land · Magnesium · recommends
    • 25 Oct 2026 · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
    • 7 Oct 2026 · recommends · Instagram ↗
      Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · neutral · X ↗
      Lists Magnesium as one of 15 supplements backed by human studies.
    • 30 Sep 2026 · recommends · Instagram ↗
      States that magnesium is a fundamental mineral governing over 600 enzymes and metabolic reactions, and recommends that most people need at least 400-500 mg/d for health, with some needing up to 600 mg/d.
    • 30 Sep 2026 · neutral · X ↗
      Lists seafood and pumpkin seeds as sources of Magnesium.
    • 6 Sep 2026 · recommends · Instagram ↗
      Thinks magnesium has some of the strongest evidence and is worth considering.
    • 17 Aug 2026 · recommends · YouTube ↗
      Recommends taking magnesium, specifically glycinate and threonate forms, 1 to 2 hours before bed for sleep benefits, noting that glycinate promotes relaxation and threonate crosses the blood-brain barrier for sleep quality and cognitive function.
    • 14 Aug 2026 · neutral · X ↗
      Notes that Boron reduces calcium/magnesium loss.
    • 10 Aug 2026 · recommends · YouTube ↗
      Notes that magnesium is important for activating thiamine into its more biologically active form, and a magnesium deficiency can impair blood sugar regulation even with adequate thiamine intake.
  • Bryan Johnson · Magnesium · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 4 May 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 2 May 2026 · uses · X ↗
      He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 21 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 15 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 14 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 8 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
    • 7 Apr 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 5 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium threonate before bed for sleep.
  • Peter Attia · Magnesium · neutral
    • 1 Jun 2026 · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 15 Sep 2025 · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
    • 6 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium for optimizing bone mineral density, suggesting a daily intake of 300 to 500 milligrams as a minimum, but personally aims for about a gram.
    • 7 Jul 2024 · recommends · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede the metabolism of vitamin D because magnesium is a cofactor in its enzymatic conversion.
    • 1 Jul 2024 · uses · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede vitamin D metabolism because magnesium is a co-factor in the enzymatic conversion of vitamin D.
    • 20 May 2024 · uses · YouTube ↗
      Takes magnesium as a straightforward supplement.
    • 28 Feb 2024 · neutral · YouTube ↗
      Mentions that magnesium intake is often super low and impactful on testosterone levels.
    • 11 Dec 2023 · uses · Facebook ↗
      Discusses the important roles of magnesium in the body, how to determine if one might be deficient, the prevalence of magnesium deficiency, and its potential cognitive benefits.

RAL Summary

Members OnlyTier 3 for Regularity: Fast Relief

This product is placed in Tier 3 because 89 percent of its 4,777 customer reviews are positive, while human trials for constipation tested higher doses of 800 milligrams or more using other forms like magnesium oxide and magnesium sulfate.

  • Magnesium: below the dose that worked in studies

Where the evidence disagrees: 9 of the 35 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Digestive system

Combine with: For enhanced regularity and overall digestive health, this magnesium supplement could be combined with a fiber supplement (like psyllium husk or glucomannan) to add bulk to stool and further aid passage. Probiotics could also be beneficial to support a healthy gut microbiome, which indirectly contributes to regular bowel movements. For more immediate, but short-term, relief, natural laxatives like senna or cascara sagrada could be considered, but these are generally not for long-term daily use.

Possible side effects: Some customers report diarrhea, stomach distress, and headaches, which they attribute to the buffered magnesium formulation.

Supplement Facts

Magnesium 420 mg
Supplement Facts
Serving Size 2 Capsules
Servings Per Container 60
Amount Per Serving% Daily Value
Magnesium (as chelated magnesium glycinate buffered)420 mg100%

Other ingredients: Hydroxypropyl methylcellulose (capsule), silicon dioxide, magnesium stearate.

Label source: Qunol · Report a label change

Show entire label
The Qunol Magnesium 420mg, Extra Strength, High Absorption, Vegetarian, 180ct label
Magnesium 420mg, Extra Strength, High Absorption, Vegetarian, 180ct

More regularity: fast relief products

Members OnlyThe highest ranked for the same goal

Graded October 28, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.