Sports Research Women's Probiotics Review
Sports Research Women's Probiotics is a dietary supplement sold as a delayed release veggie capsule. The serving size is 1 capsule, and each container holds 30 servings. Per serving, the Supplement Facts list a Women's Probiotic Blend at 298 mg, a Prebiotic Blend at 60 mg, and Cranberry powder at 60 mg. The other ingredients are potato starch, hypromellose, gellan gum, purified water, L-leucine and pectin. The printed directions say that healthy adults take 1 delayed release veggie capsule daily with food, and that it is best when taken as directed by a qualified healthcare professional. Buyers most often say the capsules are easy to swallow and leave no aftertaste, and many report feeling less bloated and having smoother digestion. The complaints that come up most are about price and the product sometimes being out of stock.
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Study, Trial or Testing Result Summary
Members Only100 human studies · 48 improved
The main ingredient is the women's probiotic blend, given at a full dose. For kidney health, results are mixed. A pooled analysis of 17 trials with 701 kidney patients found no change in kidney filtration, creatinine or urea [1]. An analysis of 16 trials found little or no difference in urea or gut-made toxins [2]. A review of 45 trials with 2266 people found very uncertain or little effect [3]. Twelve trials in people not on dialysis found no drop in creatinine [4]. On the other side, an analysis of 10 trials in 552 people with diabetic kidney disease found lower creatinine, urea and urine protein [5], and another found lower gut-made kidney toxins [6]. The prebiotic blend is only a trace amount, far below the roughly 19 grams studied, so its kidney findings likely do not apply here [7]. The cranberry dose is small and unclear compared with studied amounts. Its best evidence is fewer urinary infections, about 30% fewer across 50 trials [8], not better kidney function, and two small kidney disease trials of a larger cranberry dose found no change in inflammation or gut-made toxins [9][10]. Animal and cell studies are never counted.
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- Across 50 trials with 8857 people, cranberry products lowered the risk of urinary tract infections by about 30% overall, helping women with recurrent infections, children and people prone to infection after procedures, but not the elderly, pregnant women or people with bladder emptying problems.Cranberries for preventing urinary tract infections.
- Across 50 trials with 8857 people, cranberry products lowered the risk of urinary tract infections by about 30% overall, helping women with recurrent infections, children and people prone to infection after procedures, but not the elderly, pregnant women or people with bladder emptying problems.Cranberries for preventing urinary tract infections.
- In a review of 34 trials in 4001 children with urine reflux toward the kidneys, cranberry was tested in only a single study versus no treatment, and the abstract reports no cranberry-specific result.Interventions for primary vesicoureteric reflux.
- In 23 trials with 3335 children with repeated urinary infections, cranberry products lowered the odds of urinary infection, but no preventive option reduced kidney scarring.Prophylaxis Options in Children With a History of Recurrent Urinary Tract Infections: A Systematic Review.
- In a pooled analysis of 2,492 people with chronic kidney disease, prebiotics and synbiotics lowered blood levels of two gut-derived kidney toxins (indoxyl sulfate and p-cresyl sulfate) compared with placebo, with the effect seen only in dialysis patients.Protein-bound uremic toxin lowering strategies in chronic kidney disease: a systematic review and meta-analysis.
- In 28 trials with 1,373 people with chronic kidney disease, prebiotics lowered inflammation markers (C-reactive protein and tumor necrosis factor) but did not lower creatinine, whereas probiotics did.Effectiveness of Microecological Preparations for Improving Renal Function and Metabolic Profiles in Patients With Chron…
- In 25 trials with 1,106 dialysis patients, prebiotics ranked best at lowering indoxyl sulfate, blood urea nitrogen, a marker of oxidative damage, and inflammation markers interleukin-6 and tumor necrosis factor.Probiotics, Prebiotics, and Synbiotics Improve Uremic, Inflammatory, and Gastrointestinal Symptoms in End-Stage Renal Di…
- In 23 trials with 842 people with chronic kidney disease, prebiotics lowered creatinine and blood urea nitrogen, and biotics overall lowered some toxins and oxidative stress, but kidney filtration rate did not change.Biotic Supplements in Patients With Chronic Kidney Disease: Meta-Analysis of Randomized Controlled Trials.
- Pooling 17 trials with 701 kidney patients, probiotic-type supplements did not change kidney filtration rate, creatinine, C-reactive protein or urea compared with control.Biotic Supplements for Renal Patients: A Systematic Review and Meta-Analysis.
- In 13 trials with 671 people with chronic kidney disease, microbial supplements including prebiotics lowered inflammation and oxidative stress markers and cholesterol compared with placebo.Probiotics, prebiotics, and synbiotics for the improvement of metabolic profiles in patients with chronic kidney disease…
- In 16 trials with 645 adults with chronic kidney disease, prebiotics, probiotics and synbiotics made little or no difference to urea or gut-produced toxins, with limited evidence overall.Prebiotic, Probiotic, and Synbiotic Supplementation in Chronic Kidney Disease: A Systematic Review and Meta-analysis.
- Across 10 trials with 552 people with diabetic kidney disease, probiotics lowered creatinine, blood urea nitrogen, cystatin C and urine albumin-to-creatinine ratio, and also reduced inflammation and oxidative stress compared with controls.Probiotics improve renal function, glucose, lipids, inflammation and oxidative stress in diabetic kidney disease: a syst…
- Across 14 trials in 513 people with chronic kidney disease, prebiotic, probiotic or synbiotic treatment lowered the blood toxin p-cresyl sulfate but did not significantly lower indoxyl sulfate; prebiotic and synbiotic groups lowered p-cresyl sulfate, probiotics did not.Effects of Microbiota-Driven Therapy on Circulating Indoxyl Sulfate and P-Cresyl Sulfate in Patients with Chronic Kidney…
- In trials with 331 people with moderate to advanced chronic kidney disease, gut-targeted supplements lowered the gut-produced toxins indoxyl sulfate and p-cresyl sulfate.Impact of Gut Microbiome Modulation on Uremic Toxin Reduction in Chronic Kidney Disease: A Systematic Review and Network…
- Across 12 trials in people not on dialysis, prebiotics, probiotics or synbiotics did not lower serum creatinine compared with placebo.Effects of prebiotics, probiotics and synbiotics on serum creatinine in non-dialysis patients: a meta-analysis of random…
- In a comparison of 53 studies in chronic kidney disease, mixes of three or more probiotics ranked best for lowering creatinine, uric acid and oxidative stress markers.Gut microbiome-targeted therapeutics for chronic kidney disease: comparative efficacy of probiotic and microbial prepara…
- Across 45 trials with 2266 people with chronic kidney disease, probiotics and related supplements showed very uncertain or little to no effect on kidney function and albumin in urine compared with placebo or no treatment.Synbiotics, prebiotics and probiotics for people with chronic kidney disease.
- In 16 publications covering 903 people with diabetes, some studies showed changes in kidney markers such as creatinine and kidney filtration rate but others did not, and uric acid tended to rise, so the results were mixed.Renal Health Improvement in Diabetes through Microbiome Modulation of the Gut-Kidney Axis with Biotics: A Systematic and…
- Eight trials of 4 to 24 weeks in people with chronic kidney disease mostly reported better kidney function and lower urea, ammonia and gut-produced toxins with probiotics.Probiotics in the treatment of chronic kidney disease: a systematic review.
- A review of 9 studies in people with diabetic kidney disease found most reported probiotics reduced inflammation and oxidative stress and improved kidney function markers, with no major side effects.Effects of Probiotics on Diabetic Nephropathy: A Systematic Review.
- A narrative review of 10 kidney disease studies reported that prebiotics increased helpful gut bacteria, lowered a uremic toxin called p-cresol, and reduced inflammation and oxidative stress markers.Modulation of intestinal microbiota, control of nitrogen products and inflammation by pre/probiotics in chronic kidney d…
- A review found no randomised trials testing cranberry as a treatment for existing urinary tract infections, so there is no good evidence it works for treatment.Cranberries for treating urinary tract infections.
- A review found no controlled trials testing cranberry as a treatment for existing urinary tract infections, so there is no good evidence it works for treatment.Cranberries for treating urinary tract infections.
- In a placebo-controlled trial of 200 older adults with prefrailty or frailty, 3 months of inulin and oligofructose improved frailty, kidney function, grip strength and walking speed.Prebiotics improve frailty status in community-dwelling older individuals in a double-blind, randomized, controlled tria…
- In 192 children with recurrent urinary infections, cranberry syrup worked no worse than a med trimethoprim at preventing infection.Urinary excretion of phenolic acids by infants and children: a randomised double-blind clinical assay.
- In 150 people with non-dialysis kidney disease, 30 mL a day of lactulose for 3 months lowered blood urea more than no treatment (a drop of 5.0 vs 1.8 mg/dL), though a probiotic tablet worked better.Lactulose vs Lactobacillus acidophilus for patients with chronic kidney disease: A randomized controlled trial.
- In 136 adults with type 2 diabetes, 12 weeks of a multi-strain probiotic lowered blood urea compared with placebo, but other kidney measures such as creatinine and filtration rate did not differ.Effect of microbial cell preparation on renal profile and liver function among type 2 diabetics: a randomized controlled…
- In 126 healthy well-trained adults, 6 weeks of Bifidobacterium breve Bif195 caused no differences from placebo in kidney markers or adverse events.Safety of Bifidobacterium breve, Bif195, employing a human exercise-induced intestinal permeability model: a randomised,…
- In 120 children with persistent vesicoureteral reflux, probiotics prevented urinary infections about as well as meds over one year, with no difference in new kidney scarring.Probiotics prophylaxis in children with persistent primary vesicoureteral reflux.
- In 98 participants, Bacillus probiotics taken daily for 45 days left kidney function blood markers unchanged compared with placebo.Evaluation of Bacillus clausii CSI08, Bacillus megaterium MIT411 and a Bacillus cocktail on gastrointestinal health: a r…
- In 96 healthy adults, one or three daily bottles of a multi-strain fermented milk product for four weeks caused no difference in kidney, liver, or thyroid safety tests compared with control.Safety and functional enrichment of gut microbiome in healthy subjects consuming a multi-strain fermented milk product: …
- In 92 adults with kidney injury from sepsis, 7 days of probiotics did not improve kidney recovery or 6-month survival compared with placebo, although blood urea fell in the probiotic group.Probiotics in septic acute kidney injury, a double blind, randomized control trial.
- In 78 hospitalized COVID-19 patients over 2 weeks, a synbiotic lowered interleukin-6 compared with placebo, but kidney function markers showed no significant between-group differences.The effect of synbiotic adjunct therapy on clinical and paraclinical outcomes in hospitalized COVID-19 patients: A rando…
- In 76 people with type 2 diabetes and diabetic kidney disease, 3.2 billion CFU of a probiotic blend daily for 12 weeks lowered blood sugar, HbA1c and urine albumin compared with placebo, though kidney filtration rate did not change.Probiotics ameliorates glycemic control of patients with diabetic nephropathy: A randomized clinical study.
- In 75 overweight or obese young adults, taking Bifidobacterium breve BBr60 at 10 billion CFU daily for 12 weeks lowered weight and lowered fasting blood glucose compared with placebo; the abstract reports no kidney result.Gut Microbiome and Metabolome Alterations in Overweight or Obese Adult Population after Weight-Loss Bifidobacterium brev…
- In 75 iron-deficient women over 90 days, prebiotic plus iron-fortified flour raised liver enzymes and bilirubin, and the highest serum creatinine and urea values appeared in prebiotic groups.Prebiotics and iron fortification among women of reproductive age group - Is there an association with liver and renal f…
- In 72 people with moderate to severe kidney disease, a Lactobacillus plantarum probiotic taken for six months raised kidney filtration rate while placebo lowered it, and no probiotic users saw kidney disease progress versus 8.6% on placebo.Effects of probiotic supplementation on disease progression in patients with moderate to severe chronic kidney disease: …
- In 60 people on dialysis, 60 days of a synbiotic did not lower indoxyl sulphate compared with placebo but improved constipation and constipation-related quality of life.The effects of synbiotics on indoxyl sulphate level, constipation, and quality of life associated with constipation in c…
- In 60 adults with type 2 diabetes taking 2.8 g a day of an anthocyanin and fibre supplement for 60 days, filtration rate improved, as did blood sugar and LDL cholesterol versus maltodextrin placebo; no adverse effects were reported.Diabetes Therapeutics of Prebiotic Soluble Dietary Fibre and Antioxidant Anthocyanin Supplement in Patients with Type 2 …
- In 58 people on hemodialysis, 7 weeks of a synbiotic meal made from sorghum and probiotic milk lowered two blood uremic toxins and urea compared with a control meal.Synbiotic meal decreases uremic toxins in hemodialysis individuals: A placebo-controlled trial.
- In 57 people with advanced chronic kidney disease on a low-protein diet, probiotics for 3 months showed a trend toward lower uremic toxins, while the placebo group's toxin levels rose.Probiotics-Supplemented Low-Protein Diet for Microbiota Modulation in Patients with Advanced Chronic Kidney Disease (Pro…
- In 57 overweight adults over 8 weeks, a lifestyle program with fibre supplements was followed by significant improvements in liver and kidney function, while the placebo group showed no notable changes.A multifaceted lifestyle program for weight loss in overweight adults: evidence from a randomised clinical trial.
- In 50 people on hemodialysis, 6 months of probiotics compared with placebo lowered several uremic toxins in blood or stool and improved gut bacteria balance, while other kidney-related outcomes did not change.Effect of probiotics on the intestinal microbiota of hemodialysis patients: a randomized trial.
- In 50 people with advanced kidney disease not on dialysis, 12 grams a day of a fructooligosaccharide fiber for 3 months did not significantly lower harmful gut-derived blood toxins compared with placebo; only a non-significant trend was seen.Effect of prebiotic (fructooligosaccharide) on uremic toxins of chronic kidney disease patients: a randomized controlled…
- In 48 adults, Bifidobacterium infantis BI45 for 8 weeks left kidney function markers unchanged compared with placebo.Assessing the Safety and Probiotic Potential of Bifidobacterium longum subsp. infantis BI45: A Comprehensive Study from …
- In 47 spinal cord injury patients with neurogenic bladder, 6 months of cranberry tablets cut urinary infections to 0.3 per year versus 1.0 per year on placebo, with the most benefit in people with better kidney filtration.Evaluation of cranberry tablets for the prevention of urinary tract infections in spinal cord injured patients with neur…
- In 46 dialysis patients taking 90 billion CFU of a probiotic blend daily for 3 months, urea and a uremic toxin rose within the probiotic group, but the change was no different from placebo and inflammatory markers did not change.Probiotic Supplementation in Chronic Kidney Disease: A Double-blind, Randomized, Placebo-controlled Trial.
- In 46 people with stage 3 kidney disease, probiotics alone for 3 months did not lower uremic toxins or improve kidney filtration, while activated bamboo charcoal did.Efficacy of novel activated bamboo charcoal in reducing uremic toxins and enhancing kidney function in chronic kidney di…
- In 43 adults on peritoneal dialysis, 21 g daily of unripe banana flour for 4 weeks did not change serum indoxyl sulfate, p-cresyl sulfate, or indole 3-acetic acid compared with placebo overall, though indoxyl sulfate fell in an 11-person subgroup who took closer to the full dose.Effect of Unripe Banana Flour on Gut-Derived Uremic Toxins in Individuals Undergoing Peritoneal Dialysis: A Randomized, …
- In 42 patients with peritoneal dialysis-related peritonitis, a probiotic arm was compared with an herbal formula, and only the herbal formula lowered blood urea nitrogen and creatinine, with no kidney benefit shown for probiotics.The effects of Fushen Granule on the composition and function of the gut microbiota during Peritoneal Dialysis-Related P…
- In 41 people with type 1 diabetes and protein in the urine, a 12-week synbiotic mix did not reduce urine albumin, kidney filtration rate, inflammation or gut barrier markers compared with placebo.Effects of probiotics and fibers on markers of nephropathy, inflammation, intestinal barrier dysfunction and endothelial…
- In 40 people with reduced kidney function, 10 grams twice daily of arabinoxylan fiber for 4 weeks did not lower most gut-derived toxins or improve insulin resistance compared with maltodextrin placebo, though one toxin (trimethylamine N-oxide) dropped slightly.The Influence of Prebiotic Arabinoxylan Oligosaccharides on Microbiota Derived Uremic Retention Solutes in Patients with…
- In 39 dialysis patients completing six months, a daily four-strain probiotic capsule lowered inflammatory cytokines and endotoxin versus placebo and helped preserve residual kidney function.The effect of probiotics on serum levels of cytokine and endotoxin in peritoneal dialysis patients: a randomised, double…
- In 39 people with chronic kidney disease, a daily meal of probiotic Bifidobacterium longum milk with sorghum flakes for 7 weeks lowered uremic toxins and eased gut symptoms within the group, though the abstract does not clearly report the comparison with the control group.A Symbiotic Meal Containing Extruded Sorghum and Probiotic (Bifidobacterium longum) Ameliorated Intestinal Health Marker…
- In 37 adults with advanced kidney disease, 6 weeks of synbiotic therapy lowered one uremic toxin (p-cresyl sulfate) compared with placebo but did not significantly lower indoxyl sulfate, and albuminuria rose in the synbiotic group.Synbiotics Easing Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial.
- In 34 people with chronic kidney disease over 12 weeks, a daily synbiotic with 32 billion CFU and inulin improved estimated kidney filtration by 12% versus 8% with placebo and lowered indoxyl sulfate and C-reactive protein.The Impact of Synbiotic Treatment on the Levels of Gut-Derived Uremic Toxins, Inflammation, and Gut Microbiome of Chroni…
- In 34 trail runners taking a probiotic for four weeks before races, kidney injury markers still rose after running and did not change versus placebo, but gut inflammation was lower, with the effect strongest in ultra-distance races.Effects of race distance and probiotics intervention on kidney, muscle, and gut injury and inflammation biomarker respon…
- In 31 malnourished people on dialysis, a supplement with probiotics raised kidney-protective microRNA levels and lowered inflammation-related genes after 3 months compared with diet advice alone.Modulation of miR-29a and miR-29b Expression and Their Target Genes Related to Inflammation and Renal Fibrosis by an Ora…
- In 30 people with stage 3 or 4 chronic kidney disease, 8 weeks of the higher dose of Lactobacillus casei Shirota lowered blood urea by more than 10%.Effect of probiotics on human blood urea levels in patients with chronic renal failure.
- In 30 adults with moderate to advanced chronic kidney disease (25 finished), 1000 mg a day of cranberry extract for two months did not change inflammation, oxidative stress or related gene activity compared with placebo.Effects of Cranberry Extract (Vaccinium macrocarpon) Supplementation on Lipid Peroxidation and Inflammation in Patients …
- In 29 healthy adults, a genetically modified mouth bacteria tablet taken twice daily for one month was as safe as placebo, with no kidney or laboratory problems and no serious side effects.Study to evaluate the safety and tolerability of Streptococcus salivarius eK12, a genetically modified strain derived fr…
- In 25 adults with chronic kidney disease not on dialysis, 1000 mg a day of cranberry extract for two months did not lower gut-produced toxins or bacterial endotoxin in the blood compared with placebo.Effect of cranberry supplementation on toxins produced by the gut microbiota in chronic kidney disease patients: A pilot…
- In 23 people with advanced kidney disease and vascular calcification, 6 months of Probimel showed no clear improvement in kidney function or calcification, although it lowered indoxyl sulfate and inflammation in rats.Probiotic Supplementation in Chronic Kidney Disease: Outcomes on Uremic Toxins, Inflammation, and Vascular Calcification…
- In 21 people on dialysis, 3 months of a three-strain probiotic did not change blood TMAO levels compared with placebo.Effects of Probiotic Supplementation on Trimethylamine-N-Oxide Plasma Levels in Hemodialysis Patients: a Pilot Study.
- In 20 adults with metastatic kidney cancer starting targeted drugs, a Bifidobacterium yogurt did not change how often treatment gave clinical benefit compared with the restricted-probiotic arm (70% vs 80%).Randomized trial assessing impact of probiotic supplementation on gut microbiome and clinical outcome from targeted ther…
- In 20 healthy young men, drinking 500 mL of cranberry juice a day (diluted in water) for two weeks lowered urinary oxalate and phosphate, raised citrate, and reduced calcium oxalate stone-forming risk compared with baseline.Influence of cranberry juice on the urinary risk factors for calcium oxalate kidney stone formation.
- In 19 healthy adults over 20 days, a resistant starch and Lactobacillus acidophilus yoghurt mixture lowered the kidney's excretion of toxic ammonia compared with a regular diet.The metabolic effect of resistant starch and yoghurt on the renal and faecal nitrogen and ammonia excretion in humans as…
- In 16 people on peritoneal dialysis, inulin-type prebiotic fiber for 12 weeks lowered blood uric acid by about 10% compared with placebo, with better breakdown of uric acid by gut bacteria; the dose was not stated.Inulin-type prebiotics reduce serum uric acid levels via gut microbiota modulation: a randomized, controlled crossover t…
- In 15 people on peritoneal dialysis, inulin-type fructan fiber for 12 weeks prevented the rise in gut-made indole seen with placebo, though the dose was not stated and blood toxin levels did not change significantly.Inulin-type fructan intervention restricts the increase in gut microbiome-generated indole in patients with peritoneal d…
- In patients with mild oxalate-related kidney stone risk on a controlled diet, neither an oral probiotic nor a synbiotic lowered urinary oxalate or calcium oxalate supersaturation compared with placebo, while dietary oxalate restriction did lower urinary oxalate.Diet, but not oral probiotics, effectively reduces urinary oxalate excretion and calcium oxalate supersaturation.
- In a trial of Lactobacillus crispatus for Helicobacter pylori, kidney and liver function blood tests were not affected.Study of the effect of Lactobacillus crispatus FSCDJY67L3 on Helicobacter Pylori eradication: a double-blind randomized …
- In a placebo-controlled trial of people with irritable bowel syndrome without constipation taking at least 24 billion CFU twice daily for 12 weeks, kidney function was measured, but the abstract reports no kidney-specific result; the main finding concerned bowel symptom response and a gut bacterium that predicted it.Collinsella aerofaciens as a predictive marker of response to probiotic treatment in non-constipated irritable bowel syn…
- In people with non-dialysis chronic kidney disease, 4 weeks of Lacticaseibacillus rhamnosus L34 lowered gut-derived uremic toxins and inflammation markers compared with placebo.Lacticaseibacillus rhamnosus attenuates uremic toxins in patients with nondialysis chronic kidney disease through the an…
- In a 12-week trial in overweight men aged 50 and older, a yogurt with Bifidobacterium longum BB536 plus exercise and diet slowed a DNA-based pace-of-aging score, and a kidney-related aging marker fell, but no aging clock stayed significant after correction for multiple testing.Short-term responsiveness of DNA methylation-based aging biomarkers to a multimodal intervention comprising exercise and…
- In people with type 2 diabetes, kidney disease and constipation, Bifidobacterium bifidum G9-1 for 12 weeks increased normal stool consistency, especially in those aged 65 and over, men, and those with better kidney filtration.Effects of age, sex, and renal function on bowel movement-improving effects of Bifidobacterium bifidum G9-1 on constipat…
- In people with end-stage kidney disease, resistant starch supplementation for 8 weeks increased beneficial gut bacteria and lowered blood markers of inflammation compared with placebo; the dose and number of participants were not stated.Amylose resistant starch (HAM-RS2) supplementation increases the proportion of Faecalibacterium bacteria in end-stage re…
- In a 6-month placebo-controlled crossover trial of 46 people with stage 3 or 4 chronic kidney disease, a daily probiotic with 90 billion CFU lowered blood urea nitrogen in 63% of patients, a significant change compared with placebo.Pilot study of probiotic dietary supplementation for promoting healthy kidney function in patients with chronic kidney d…
- In 40 people on dialysis, 3 months of probiotics lowered a gut-derived kidney toxin (P-cresyl sulfate), inflammation and a gut leakage marker compared with controls.The Effect of Probiotic Use on Gut Leakage Measured by Zonulin and its Relation to P Cresyl Sulfate and Inflammation in …
- In 16 people with chronic kidney disease, 19 grams a day of inulin added to a low-protein diet for 6 months significantly lowered blood uric acid and C-reactive protein compared with a low-protein diet alone.Effect of Low-Protein Diet and Inulin on Microbiota and Clinical Parameters in Patients with Chronic Kidney Disease.
- In 12 healthy men, 330 ml of cranberry juice lowered urine pH and raised urinary oxalate and uric acid supersaturation compared with water, so it may help some stone types but may increase the risk of others.Effect of blackcurrant-, cranberry- and plum juice consumption on risk factors associated with kidney stone formation.
- In 11 healthy adults, 4 weeks of the VSL#3 probiotic reduced oxalate absorption overall, with the largest reduction in four people who absorbed high amounts of oxalate at baseline; this may lower kidney stone risk.Probiotic-induced reduction of gastrointestinal oxalate absorption in healthy subjects.
- In 8 hemodialysis patients with end-stage kidney disease, freeze-dried Lactobacillus acidophilus lowered serum dimethylamine and nitrosodimethylamine, two toxins linked to kidney failure.Biomodulation of the toxic and nutritional effects of small bowel bacterial overgrowth in end-stage kidney disease using…
- In 30 people with diabetes and kidney disease who had constipation, Bifidobacterium bifidum G9-1 for 12 weeks improved stool form and urinary albumin decreased at week 6, with no change in filtration rate in this open-label single-group study.Efficacy of probiotics (Bifidobacterium bifidum G9-1) in patients with type 2 diabetes mellitus and chronic kidney disea…
- In 28 people with early kidney disease, a probiotic lowered inflammation markers and improved iron status and gut bacteria compared with placebo, while placebo showed no change.An open-label, randomized, placebo-controlled study on the effectiveness of a novel probiotics administration protocol (…
- In 23 people with calcium oxalate kidney stones, 20 days of probiotics with potassium citrate and magnesium left no patients with crystals in their urine at 1 and 3 months, though crystals returned in some by 6 and 12 months.Oral supplementation with probiotics, potassium citrate, and magnesium in reducing crystalluria in stone formers: A phas…
- In 16 volunteers taking 900 mg of cranberry extract daily for 7 days, urine from men blocked bladder bacteria from sticking to cells, while urine from women did not.Influence of Cranberry Extract on Tamm-Horsfall Protein in Human Urine and its Antiadhesive Activity Against Uropathogen…
- In 13 adults with chronic kidney disease taking a prebiotic fiber (inulin) daily for 12 weeks in an open-label pilot without a placebo group, urine levels of two gut-derived kidney toxins, indoxyl sulfate and p-cresol sulfate, fell during treatment.Prebiotic Administration to Chronic Kidney Disease Patients Modifies Their Fecal Microbiome and Host Metabolism.
- In 5 healthy volunteers taking cranberry concentrate tablets at the manufacturer's dose for 7 days, urinary oxalate (a stone-forming substance) rose by an average of 43%, and calcium and phosphate excretion also rose, raising concern about kidney stone risk.Dietary supplementation with cranberry concentrate tablets may increase the risk of nephrolithiasis.
- In a large US population survey of 15,291 adults, people who reported taking probiotics or prebiotics had lower urine albumin levels, lower rates of kidney disease in those with high blood pressure, high cholesterol, or diabetes, and lower all-cause mortality, though this is an association and not proof of cause.The relationship between probiotics and prebiotics, kidney dysfunction and mortality - Results from a longitudinal cohor…
- In a survey of 2,665 adults with type 2 diabetes, those who took probiotics, prebiotics, synbiotics, or yogurt had lower odds of diabetic kidney disease, but this association does not prove the supplements caused the benefit.Association Between Probiotic, Prebiotic, Synbiotics, and Yogurt Supplements and Diabetic Kidney Disease: The National H…
- In a two-year study of 1017 postmenopausal women, cranberry juice use was not linked to a lower risk of bladder infection after adjusting for other factors.Predictors of urinary tract infection after menopause: a prospective study.
- In a survey of 117 parents of children in a kidney clinic, 29% gave cranberry products for kidney or urinary problems and most felt it helped, but no controlled test of benefit was done.Cranberry use among pediatric nephrology patients.
- In 103 kidney stone patients surveyed, cranberry juice products contained only about 1.5 to 4.7 mEq of alkali per serving, and the study did not test whether cranberry improved kidney stone outcomes.Complementary and Alternative Medicine Use in First-time and Recurrent Kidney Stone Formers.
- In a survey of 95 kidney stone patients, 20% used cranberry extract and about 65% thought it was probably safe, but the authors state its risks and benefits for kidney stones remain unknown.Patient Perceptions of Dietary Supplement Use and Kidney Stone Disease.
- In a retrospective study of 82 kidney transplant recipients, cranberry juice (100 mL daily) with or without L-methionine cut urinary tract infections by about 58% over a year.Prophylaxis of recurrent urinary tract infection after renal transplantation by cranberry juice and L-methionine.
- In 39 children, a daily cranberry, probiotic and vitamin C supplement for six months reduced recurrent urinary tract infections, and 69% stayed infection-free over the full follow-up.Effects of a Cranberry, Probiotic, and Vitamin C Supplement on Recurrent Urinary Tract Infections in Children-A Cohort S…
- In 128 infants with vesicoureteral reflux, a year of Lactobacillus acidophilus was not significantly different from meds for repeat urinary infections or kidney scarring (32.8% vs 40.6% had recurrent infection).Probiotics prophylaxis in infants with primary vesicoureteral reflux.
- In 16 volunteers taking 900 mg cranberry extract daily for 7 days, urine showed some ability to block E. coli from sticking to the bladder lining, but bacterial gene activity was not changed; no kidney outcome was measured.Antiadhesive natural products against uropathogenic E. coli: What can we learn from cranberry extract?
- Probiotics lowered E. coli and indoxyl sulfate levels and improved heart outcomes in rats and in people with chronic kidney disease and heart failure.Gut-microbiota-derived indole sulfate promotes heart failure in chronic kidney disease.
- In experimental models, a cranberry-derived diet reduced kidney stone crystal formation linked to a urinary bacterium, but this was not tested in people.Hippuric acid metabolism by Corynebacterium glucuronolyticum-like bacteria promotes calcium oxalate crystallization.
Review Totals and Summary
Members Only2,210 reviews · 92% positive
Across the stores that sell it, Sports Research Women's Probiotics carries about 2210 ratings, and 82% of the starred reviews give 4 or 5 stars. Buyers are mostly happy, with praise centered on digestion and how easy the capsules are to take, and a smaller set of complaints about price, stock and delivery. **What buyers say it did for them:** The most common story is a calmer gut. Several people mention less bloating, with one writing "I’ve felt a lot less bloated" and another saying "no more bloating or bad moods." Others describe easier digestion, less gas and more regular trips to the bathroom. A few say they noticed a change within a month, and some mention vaginal health or balance as a reason they like it. One buyer said they could not tell how it works for UTIs because they rarely get them. Some reviewers are newer and say they hope it will work. **What they complain about:** The complaints are mostly practical. One buyer says it is "sometimes out of stock for long periods." Another reports that a tracking number showed delivery but the package never arrived. These are not about how the capsule itself performs. **Taste, smell, pill size and form:** Buyers describe the veggie capsule as normal in size and easy to swallow. One says "No after taste, easy to swallow," and another says the capsules "go down very easily." Several like that it is a delayed release capsule, and some are glad the cranberry is already in it so they do not need a separate cranberry product. A few comment that the packaging and the container are good. **Value for money:** Opinions split a little. One buyer calls it "not so expensive as other products in the market," and another likes the price. A three star reviewer says it is fairly expensive when two people each go through a bottle every month, and wishes it "came in a larger quantity at a lesser cost." One buyer mentions that subscribing was easy and delivery was on time. **Who it seems to suit and who it did not:** It seems to suit women who want a daily probiotic that is gentle on the stomach and simple to fit into a routine, taken with a meal. Buyers who already use other products from the same brand say they trusted it for quality. The people it suited least were those bothered by cost, those who ran into stock problems, and the one buyer whose order did not arrive.
Biohacker Summary
Members Only5 of 10 recommend it
Probiotic blend is the main ingredient, and three of the ten panelists spoke about it. Two of them recommend or use a daily product that pairs probiotics with prebiotics, one for its scientific approach and multi-stage delivery, the other for its 24 strains, capsule-in-capsule design, and reported help with bloating, gas, and regularity. The third panelist is neutral, simply noting that a full probiotic blend is included for the gut, though he earlier recommended adding a probiotic and prebiotic to a daily routine because gut health affects the whole body. One panelist suggests taking it a couple of hours apart from fermented foods, and none gave a dose or reported stopping. Cranberry is a smaller ingredient in this product, and panelists mostly mention it for urinary tract support and for feeding a gut bacterium, with one caution that unsweetened cranberry juice carries carbs and sugar.
See all 8 biohackers →Hide the biohackers
Thomas DeLauer · Probiotic Blend · recommends
- Recommends Seed probiotic, stating it's the only probiotic he would ever recommend due to its scientific approach and multi-stage delivery system.
- Recommends cranberry for kidney health, explaining that proanthocyanidins block bacterial adhesion.
- Highly recommends Seed Daily Synbiotic, a prebiotic and probiotic, to capitalize on the beneficial effects of fermented foods and improve gut health, suggesting it be taken a couple of hours apart from fermented foods.
- Recommends cranberry capsules, citing an RCT where a cranberry group had greater reductions in fatty liver, lower insulin, and improved insulin resistance, attributed to terostilbene activating fat burning and reducing triglyceride accumulation.
- Recommends cranberry extract, referencing a study where 144 milligrams of cranberry extract for 6 months reduced insulin levels and insulin resistance, leading to less fat deposition in the liver.
- Recommends Seed Daily Synbiotic, a prebiotic and probiotic in one, especially when changing diet or acclimating to a new diet style, and offers a discount code.
- Recommends Seed's daily symbiotic, which is a prebiotic and probiotic in one capsule, as a great tool to use in conjunction with honey to shift and alter the microbiome rapidly.
- Is a huge fan of Seed Daily Symbiotic and states it's the only probiotic he personally uses, appreciating their transparency in publishing clinical trials, even when results aren't in their favor.
- Recommends Seed's daily symbiotic, which contains a prebiotic and probiotic in one capsule, for good digestive health and notes the brand's commitment to microbiome research.
- Recommends Seed Daily Synbiotic, stating it's the only probiotic he would ever recommend, especially when in a caloric deficit or changing one's diet, due to its unique capsule-in-capsule technology for better colonization of bacteria in the gut.
- Recommends Seed's daily symbiotic, which contains a prebiotic and probiotic in one capsule, for those looking to improve their gut microbiome, noting its unique technology and the company's funding of microbiome research.
- Recommends Seed, a synbiotic that combines a probiotic and prebiotic, for people who are intermittent fasting and may not be getting a wide variety of food, to help support their gut biome.
- Likes that Ample includes a probiotic blend, specifically mentioning L-rhamnosus as a highly researched strain.
- Thomas DeLauer recommends cranberry extract, noting that clinical trials show it improves insulin sensitivity and reduces liver fat, and considers it one of the most under-appreciated liver foods.
Dr. Mark Hyman · Probiotic Blend · uses
- Continues to recommend and take Seed's DS-01 Daily Synbiotic, highlighting its 24 unique probiotic strains, capsule-in-capsule technology, and clinical evidence for reducing bloating, alleviating gas, and improving regularity.
- Mentions that cranberry has super beneficial effects on Akkermansia muciniphila, a keystone species that protects the gut lining, prevents leaky gut, reduces inflammation, and helps metabolic health.
- Was given cranberry as part of a program to rehab his gut and rebuild bacteria.
- States he took cranberry in high doses every day in concentrates to regrow his Akkermansia when he had colitis.
- Recommends cranberry juice because its ellagitannins stimulate the gut to secrete healthy mucus, which Akkermansia bacteria loves to grow in.
- To recover from colitis, Dr. Mark Hyman created an "Akkermansia shake" that included concentrated cranberry concentrate.
- Recommends cranberry juice because it helps grow more Akkermansia due to its ellagitannins, which cause the gut to secrete more healthy mucus.
- Recommends cranberry because it fertilizes important gut microbes called Akkermansia, which, when at healthy levels, reduce the risk of autoimmune disease, diabetes, and cancer.
- Recommends cranberry as a good red plant food and mentions it was part of a protocol that helped a cancer patient raise Akkermansia levels.
- Notes that polyphenols in cranberry are loved by bacteria, fertilizing the good guys in the gut.
- Recommends cranberry because it fertilizes Akkermansia, an important microbe in the gut, which can reduce the risk of autoimmune disease, diabetes, and cancer, and also suggests it to help grow Akkermansia back for improved cardiometabolic health.
- Gave a good general probiotic blend to a patient to improve gut health.
Ben Greenfield · Probiotic Blend · neutral
- Notes that IM8health includes a full probiotic blend for the gut.
- Notes that IM8health includes a full prebiotic blend for the gut.
- Ben's test recommends taking cranberry to increase akkermansia.
- Recommends Seed's Daily Synbiotic for those who want to add a probiotic + prebiotic to their daily routine, noting that gut health affects whole-body health.
- Recommends cranberry juice as it contains natural chemicals that prompt the secretion of mucus, supporting the growth of Akkermansia muciniphila.
- Recommends Organifi Red, a low-sugar powder with organic ingredients like Siberian ginseng, cordyceps, acai, beets, pomegranate, raspberry, cranberry, and strawberry, for increasing nitric oxide, adaptogenic energy, and building new blood cells.
- Specifically recommends cranberry-containing polyphenols supplements.
- Provided new options for polyphenols and flavonoids, explaining why cranberry could be especially good for the individual.
- Recommends Organifi Red Juice, describing it as a blood builder that can increase blood flow, containing ingredients like beets, pomegranate, raspberry, cranberry, and strawberry, and notes that his kids drink it too.
- Recommends Organifi Red Juice Powder, describing it as an anti-aging, high antioxidant blend with acai, pomegranate, cranberry, raspberry, blueberry, strawberry, cordyceps, ginseng, reishi mushroom, and rhodiola, which he uses for a 'blood boost' in his morning smoothie.
- Says his buddy Drew Canole's company Organifi launched a red juice, which he tasted at Drew's house before a workout and it blew his mind and body. He describes it as a blend of acai, beet, pomegranate, cranberry, raspberry, blueberry, strawberry, and adaptogenic herbs like cordyceps, Siberian ginseng, reishi mushroom, and rhodiola, which are amazing for fat burning.
- Ben Greenfield uses Life Shots which contain cranberry.
- Uses probiotic blends APO-808™ and APO-19™ as part of Dr. John Lieurance's Travel Hacking Kit, which are designed to assist in gut health by placing probiotics in the lower intestine.
- Ben states that cranberry extract acts similarly to D-mannose but is not as effective.
Siim Land · Cranberry · neutral
- Mentions cranberry oil as a natural agent with a low SPF of 5-8, which can be used as a complementary ingredient in sunscreens but is insufficient as a primary sunscreen.
Dave Asprey · Cranberry · neutral
- Notes that cranberry extract is good for UTIs and guesses it probably has other beneficial effects, though there is less research on its direct link to the vaginal microbiome.
- Discusses the potential of cranberry extract to deliver bioactive constituents that protect the urinary tract from infection, without the unwanted sugar found in cranberry juice.
- Recommends taking extra unsweetened cranberry juice to detoxify the lymphatic system, as it targets the lymphatic system and digests fats through the lymphatics.
- Suggests that a cranberry extract could deliver the bioactive constituents that protect the urinary tract, without the unwanted sugar found in cranberry juice, especially since the FDA allowed a qualified health claim for cranberry.
Peter Attia · Cranberry · neutral
- Mentions cranberry juice as a recommended remedy for UTIs, illustrating the connection between food consumption and the vaginal microbiome.
Dr. Eric Berg · Cranberry · recommends
- Dr. Berg suggests trying cranberry as a natural a med.
- States that cranberry juice is not very effective for an existing UTI and contains sugar, making it less ideal.
- Recommends cranberry for UTIs, highlighting its anti-adhesive properties that prevent bacteria from accumulating in the bladder and its ability to inhibit biofilms.
- States that unsweetened cranberry juice is really good for UTIs because it contains compounds that prevent bacteria from sticking to the bladder.
- Warns that unsweetened cranberry juice has a significant amount of carbs and has been observed to stop weight loss in some individuals, so it should be avoided during a fast.
- States that while cranberry juice might be good for the kidney, it is not necessarily good for dissolving stones.
- Explains that a small amount of cranberry is acceptable on a ketogenic diet because cranberries are tart and have less sugar than other berries, fitting within the daily carb allowance.
- States that cranberry does not help dissolve kidney stones; it only helps lessen the stickiness of bacteria in the bladder.
- Dr. Berg recommends unsweetened cranberry juice for its immune-enhancing benefits, specifically for preventing microbes from sticking to inner organs and for urinary tract infections, H. pylori, and E. coli.
- Uses the example of a patient who started drinking cranberry juice and developed pain, explaining that cranberry affects the kidneys and dissolves kidney stones, suggesting the pain was caused by dissolved crud moving through the urinary tract.
Andrew Huberman · Cranberry · recommends
- Andrew Huberman notes that cranberry, specifically 36 milligrams of soluble proanthocyanidins (PACs), is in the American Urological Association guidelines for preventing recurrent UTIs.
RAL Summary
Members OnlyTier 4 for Kidney Health
The tier 2 grade rests on cranberry, a minor 60 mg ingredient whose strongest studies concern urinary infections at much larger doses rather than kidney function, while the main probiotic blend shows mixed results for kidney health. So it is graded Tier 4, lower than the rules alone gave.
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 38 of the 100 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Digestive system, Urinary system, Kidneys, Reproductive system
Possible side effects: No major side effects reported. Small studies found cranberry may raise some kidney stone risk markers.
Supplement Facts
Women's Probiotic Blend 298 mg · Prebiotic Blend 60 mg · Cranberry, Powder 60 mg
| Women's Probiotic Blend | 298 mg | † |
| Prebiotic Blend | 60 mg | † |
| Cranberry, Powder | 60 mg | † |
Other ingredients: Potato Starch, Hypromellose, Gellan Gum, Water, Purified, L-Leucine, Pectin.
Directions: Suggested Use: As a dietary supplement, healthy adults take 1 delayed release veggie capsule daily with food. Best when taken as directed by a qualified healthcare professional.
Barcode (UPC) 023249091387 · Label source: NIH label database · Report a label change
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Graded November 11, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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