SuperSmart EDTA Detox 1000 mg Review

SuperSmart's EDTA Calcium Disodium supplement is sold as 180 vegetarian capsules and is presented as a premium supplement formulated for overall well-being. The product is described as supporting the body's natural processes in response to environmental exposure, playing a role in maintaining mineral balance, and providing antioxidant support. The page explains that EDTA, short for ethylene diamine tetra-acetic acid, is a compound known for its ability to bind with certain minerals and metals. It has been studied for its role in maintaining mineral balance and supporting the body's natural detoxification processes, and it also interacts with calcium, a mineral involved in many physiological functions including vascular health. The page states that the body has built-in mechanisms to process and eliminate various substances, and that compounds such as EDTA have been studied for their role in supporting these pathways. It notes that environmental factors, diet, lifestyle, and everyday stressors can influence how people feel, and that maintaining balance in natural processes is important for long-term wellness. The supplement is described as generally well-tolerated by most adults, with any temporary changes in energy or digestive comfort described as typically mild and short-lived. The page advises that people taking medications, especially those related to blood sugar management or circulation, should consult a healthcare provider first. Each serving is four capsules, providing 1,000 mg of EDTA Calcium Disodium, with each vegetarian capsule containing 250 mg. The recommended use is two capsules twice a day on an empty stomach, one hour before or two hours after a meal. The container holds 45 servings. The product is labeled vegan, gluten-free, lactose-free, GMO-free, additive-free, and free of controversial excipients. The other ingredients are the vegetable capsule made of hypromellose, acacia gum, and white rice flour. The page includes warnings not to exceed the recommended daily dose, not to take the product with food or with other nutritional supplements, and to keep it out of reach of children. Adults are advised to consult a healthcare provider if pregnant, breastfeeding, or managing a health condition. Storage is recommended in a cool, dry place away from direct light, heat, and humidity. The page also notes that the statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure, or prevent any disease.

Product Focus: CirculationAlso covers:Heart
Tier ⓘ
Tier 4 · Rank 3
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 3 within Tier 4 for Circulation; 28 of 55 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
46 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
97% of 81
Biohacker Mentions
2 of 10
Cost per month
$15

Study, Trial or Testing Result Summary

Members OnlyHuman studies

We found no human studies on EDTA and heart health or blood flow to show here. The only ingredient is EDTA at 1000 mg per serving, and the store lists it as the calcium disodium form. No study results were given for this ingredient and this goal. That means we cannot say from research whether this capsule improves blood flow, heart health or circulation, or how large any effect might be. What we have instead is buyer feedback. Most buyers are happy, and several say they use it to clear heavy metals such as lead. One reviewer says their heart feels healthier and lighter. Personal reports like these cannot show whether the product itself caused the change, and they are not a substitute for controlled trials. Anyone thinking of taking EDTA for heart or blood flow reasons should know that this listing has no study evidence behind that use. It is worth talking it over with a doctor, especially if you already take heart medicines or have kidney problems. Animal and cell studies are never counted.

Review Totals and Summary

Members Only81 reviews · 97% positive
81 reviews · Walmart 37 · Nordstrom 27 · SuperSmart 17
97% positive0% neutral3% negative

Buyers are mostly happy with SuperSmart EDTA Detox 1000 mg, which carries about 54 ratings across the stores that sell it. Most feedback is short and positive, though it gives little detail about how the capsules were used or for how long. Only capsule feedback is covered here; reviews of other forms were left out. **What buyers say it did for them:** Many say it works, and some name specific aims. Several mention heavy metals, especially lead. One says it is "great when you need to get lead out of your system," and another says it "detoxes heavy metals from the body." Others describe feeling better in the heart and chest: "it makes my heart feel healthier and lighter." The same reviewer says it "seems to help breathing too." One buyer reports "good test results lately," and a first-time EDTA user was "very pleasantly surprised at the results." One person says it is "working better than doing green drinks alone." Other buyers give only a general verdict, such as "It does the job" or "I believe this product works." **What they complain about:** Complaints are rare. One buyer gave a single star, but not because the product failed. They were afraid of side effects, wanted to return it, and could not because they live in another country. That reviewer's own words were "afraid to take this medicine because of side effects." The store summary says no written review raises a problem with taste, size, side effects, effectiveness, the capsules, or ordering. The main limitation is how short the feedback is, since most reviews give a verdict without saying how long the product was used. **Taste, smell, pill size or form:** The reviews do not discuss these, so there is nothing to report on them. The product here is capsules, and no one comments on how easy they are to swallow. **Value for money:** Opinions on value are positive. One buyer calls it "the best brand for the money," and another says "Good prices and I will be reordering." The same review praises fast delivery and an "awesome company," so service gets a good word as well. **Who it seems to suit and who it did not:** It seems to suit people who want a heavy-metal or lead-focused detox product, and those who already follow a cleansing routine, such as green drinks. It also appeals to buyers who value price and are willing to reorder. A first-time EDTA user found it a pleasant surprise, so newcomers were not put off. The one person it did not suit was the buyer who feared side effects and regretted the purchase. That is a worry about taking it, not a report of what happened. Since the written feedback is brief and nearly all positive, anyone weighing it up has few details on dosage or timing to go on.

Biohacker Summary

Members Only2 of 10 recommend it
2 of 10 biohackers on our panel recommend it

EDTA is a smaller ingredient in this product, and four of the ten panelists spoke about it. Two lean toward using or recommending it, mainly to pull out lead and other heavy metals, and they also mention it for breaking up biofilms and for reducing calcium in arteries. One of them has had intravenous treatment for high lead and uses suppositories and a toothpaste containing it, and another has used a liposomal form. For severe iron overload, one panelist suggests it but says other needed minerals must be replaced afterward. The other two are more guarded: one says it must be used safely with a doctor's supervision, and one warns that using it incorrectly, especially by intravenous drip, can be disastrous.

See all 4 biohackers →Hide the biohackers
  • Dr. Eric Berg · EDTA · neutral
    • 18 Sep 2025 · neutral · YouTube ↗
      Mentions EDTA as another form of therapy for gallstones, describing it as a chelator that connects to calcium and other minerals to pull them out of the body.
    • 27 Sep 2023 · recommends · Podcast ↗
      Suggests Calcium EDTA as a great natural remedy to help protect against lead poisoning.
    • 4 Sep 2023 · recommends · YouTube ↗
      Recommends calcium EDTA as a chelator to help pull out heavy metals like lead.
    • 25 Dec 2022 · neutral · YouTube ↗
      Mentions EDTA as a chelation-type remedy that breaks up biofilms.
    • 4 Nov 2022 · recommends · YouTube ↗
      For severe cases of hereditary hemochromatosis, Dr. Eric Berg suggests taking EDTA as a very powerful chelator to remove iron, with the caveat that other necessary minerals must be replenished.
    • 18 Nov 2021 · recommends · YouTube ↗
      Recommends taking a chelator called EDTA, which can help remove some of the calcium inside the arteries.
    • 26 Aug 2021 · warns · YouTube ↗
      Warns that EDTA pulls out other minerals like magnesium and zinc, and can cause side effects like arrhythmias, hypocalcemia, hypotension, prolonged bleeding, and cramps if not managed carefully.
    • 25 Aug 2021 · recommends · YouTube ↗
      Recommends considering taking a chelating product called EDTA, explaining that it binds with things like mercury and pulls them out of the body.
    • 11 Jul 2021 · recommends · YouTube ↗
      Recommends EDTA, a chelator that helps pull out excess calcium from the arteries, noting it's very powerful for circulation and other things, but requires a specific method of taking it to replace desired minerals.
    • 17 Sep 2020 · neutral · Podcast ↗
      Dr. Berg mentions EDTA.
  • Dave Asprey · EDTA · uses
    • 16 Sep 2024 · uses · YouTube ↗
      Stated that EDTA is the only thing they have found that will help with lead, and recounted a personal experience where intravenous EDTA treatment significantly improved their skin color.
    • 10 Sep 2024 · uses · YouTube ↗
      Dave Asprey recounts receiving intravenous EDTA treatment in his mid-to-late 20s for very high lead levels, which resulted in his skin turning pink after just one treatment.
    • 21 Feb 2023 · recommends · YouTube ↗
      Dave Asprey recommends EDTA chelation suppositories as a gentle and affordable way to reduce calcium in arteries, noting that it's a long-term process.
    • 16 Dec 2022 · uses · YouTube ↗
      Mentions that EDTA is used in their custom toothpaste to dissolve calcium and other minerals to remove plaque and biofilms.
    • 26 Apr 2022 · recommends · YouTube ↗
      Recommends asking for EDTA during chelation therapy, as it works well for lead, and notes it can also be found in suppositories.
  • Dr. Mark Hyman · EDTA · neutral
    • 8 Jan 2024 · neutral · YouTube ↗
      Mentions that EDTA can be used for lead poisoning, but it needs to be used properly and safely with a doctor's supervision.
    • 9 Jun 2023 · neutral · YouTube ↗
      Notes that EDTA can be used to remove lead from the body, but it requires proper and safe use under doctor supervision.
  • Ben Greenfield · EDTA · uses
    • 3 Oct 2019 · uses · YouTube ↗
      Sometimes uses a product called Interfase Plus, which contains EDTA, to chelate out minerals that are part of the biofilm matrix.
    • 18 Feb 2017 · uses · YouTube ↗
      Says that EDTA is one of the synthetic keyers they use, specifically in a liposomal format, for detoxification.
    • 31 Aug 2016 · warns · YouTube ↗
      Mentions EDTA as a true binder but implies it can be used incorrectly, leading to disastrous results, similar to other allopathic binders.
    • Date not recorded · warns · Website ↗
      Mentions EDTA as a true binder but warns that allopathic use of such binders, especially via IV, can be incorrect and disastrous for chronic poisoning.

RAL Summary

Members OnlyTier 4 for Circulation

Tier 3 needs some study support, but no human studies on blood flow were given for EDTA, so the evidence is thin and only supports tier 4. So it is graded Tier 4, lower than the rules alone gave.

  • Emerging: not enough evidence to rank higher yet.
  • No human studies on this goal for its ingredients.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Cardiovascular system

Combine with: If using a chelator like EDTA at all, which should be done only under medical guidance, pair it with a broad mineral replacement taken at a separate time of day, such as zinc, magnesium, and a trace mineral complex, because EDTA can strip essential minerals. A B-complex and vitamin C can offset some losses and support antioxidant defense. For the actual goal of cellular and DNA repair, better-supported options include NAD+ precursors (nicotinamide riboside or NMN), resveratrol or pterostilbene, quercetin, alpha-lipoic acid, CoQ10 or PQQ for mitochondrial support, and omega-3s. Glutathione or NAC supports detox and antioxidant capacity. Kidney and liver function should be checked before any chelation.

Possible side effects: No major side effects reported. One buyer said they were afraid to take it because of possible side effects but did not report any.

Supplement Facts

Ethylenediaminetetraacetic Acid 1000 mg
Supplement Facts
Serving Size 2 Capsule(s)
Servings Per Container 45
Amount Per Serving% Daily Value
Ethylenediaminetetraacetic Acid1,000 mg†
† Daily Value not established.

Other ingredients: Acacia Gum, White Rice Flour.

Directions: Recommended use: Adults. Take two vegetarian capsules twice a day (ie, 1000 mg of EDTA). Must be taken on an empty stomach, one hour before, or two hours after meals.

Barcode (UPC) 05453003820246 · Label source: NIH label database · Report a label change

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Graded November 7, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.