SuperSmart Wild Amazonian Formula Review
Supersmart Wild Amazonian Formula is presented by brand SuperSmart as a clever mix of five wild plants from the Amazon. The brand describes itself as a pioneer in dietary and nutritional supplements for over 30 years, offering top and pharmaceutical quality products since 1992. The product is described as an effective form for men and women and is encapsulated in a vegetarian capsule, which the page says ensures maximized effectiveness for all. The listing states that the company's products and formulas are constantly updated to reflect the latest scientific research, advances, and production methods. The brand says it offers Gluten Free, Non-GMO, Additive Free, Soy Free, Nano Particles Free and Vegan Friendly products. It notes that more than 400 Supersmart products are made in GMP and HACCP certified facilities, with facilities located in the EU and the USA. The brand says its guiding principles, which prioritize quality, safety, efficacy, and scientific validation, have remained the same for the past 30 years. The page lists the formula's five hand-harvested, wild Amazonian plants: Cat's Claw (Uncaria Tomentosa), Suma Root (Pfaffia paniculata), Pau d'arco (Lapacho), Graviola (Soursop), and Mullaca (Physallis angulata). It is described as a unique blend of Amazonian medicinal plants that is plant based, non-GMO, gluten free, and vegan. Recommended use on the page is to take 2 capsules twice a day. The page suggests that to support immunity, it is best to begin a six-month course of supplementation in the autumn, and that in all other cases it can be continued for longer. The page also offers a 100% satisfaction promise, saying that since 1992 the brand wants customers to be fully satisfied and invites questions by contacting the company 24/7. The item is currently shown as sold out, and the page says it is no longer available. Nordstrom lists the item number as 10565112 and a core product ID of 333333M7HC. Shipping is listed as free, and items sold and shipped by SuperSmart can be returned by mail or to a Nordstrom store within 90 days of when the item shipped, in new condition with tags attached. Gift options are offered at checkout, including an email gift message. No customer reviews are currently posted on the page.
Study, Trial or Testing Result Summary
Members OnlyHuman studies
No study in people has tested this formula or any of its five herbs for thinking, memory or mental clarity. The only research found is on cat's claw, and all of it is in animals. In middle-aged rats, cat's claw extract given for one month or one year shortened the time needed to find a hidden platform in a water maze, and the one-year group spent more time near the platform zone [1]. In lab and mouse experiments, a cat's claw extract and one of its plant compounds reduced the brain plaques and tangles seen in Alzheimer's disease, improved short-term memory in mice bred to develop these changes, and lowered brain inflammation [2]. In mice, cat's claw alkaloids given as single injections reduced memory loss caused by a drug [3]. These results may not carry over to people, and they do not show whether the amount in this product, about 800 mg a day, is enough. No studies on brain function were found for suma, graviola, pau d'arco or mullaca. Animal and cell studies are never counted.
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Review Totals and Summary
Members Only28 reviews · 88% positive
**Overall picture:** The feedback is warm but thin for this product. Almost none of it names the SuperSmart Wild Amazonian Formula or says which form was bought. Most of it praises the store and its other supplements, so treat it as weak evidence about these capsules. No review identifies the form, so I could not separate capsule reviews from those of other forms, and I have not left any out on that basis. **What buyers say it did for them:** The closest match is a long-term user of ParActin, who is the only reviewer describing effects over time. They say they "can really tell the difference" and that it "helps aches and pains recover quicker." They felt less well after they stopped taking it and better once they resumed. Other reviews describe results from other products. One says a supplement was the only thing that helped melasma after ten years of trying, another recommends eye-pressure pills for glaucoma patients, and a third credits a Bacillus subtilis product with helping their microbiome. It is unclear whether any of these refer to this formula. One buyer is still waiting, giving a product 90 days before judging it. **What they complain about:** The reviews contain no complaints about the product, the store, or delivery. That is encouraging, but most of the entries are very short and general. **Taste, smell, pill size or form:** Nothing in the reviews covers taste, smell, capsule size, or how the product is taken. I can't tell you anything on these points. **Value for money:** Only one reviewer comments on price, calling it "a reasonable price for what we're getting." The same reviewer calls the brand "clean," with "no bad ingredients." That is one opinion, and it is not clearly about this formula. **Ordering and delivery:** This is the most common praise. Reviewers describe the store as "easy to order" and "fast," and say orders arrived "on time and in good condition." One mentions good follow-up from the seller, and another likes the variety available. A few call the supplements "high quality" without being specific. **Who it seems to suit and who it did not:** The only person described in any detail is the long-term ParActin user looking for help with aches and recovery. They pair it with a turmeric/curcumin supplement, so their results may not come from the formula alone. Other reviewers were looking for a calcium supplement, skin pigmentation help, or eye health support, but these needs relate to other products. Nobody reports that it did not suit them. **Bottom line:** If you are buying mainly for reliable ordering and delivery, the feedback is positive. If you want evidence about how these capsules perform, taste, or compare on price, the reviews give very little to go on.
Biohacker Summary
Members Only3 of 10 recommend it
Five of the ten panelists spoke about cat's claw, the main ingredient, and the group leans positive: two recommend it, one uses it in a regular rotation, and two mention it without taking a side. Reasons given include blocking inflammation and keeping the brain clear, supporting the body against tick borne infections and mycoplasma, cleaning the blood and addressing Epstein-Barr, and helping with autoimmune conditions and rheumatoid arthritis. One panelist noted that herbs like this are hard to find in the West with good quality and dosing, and another said it can build up defenses without meds. Nobody gave a dose or preferred form, nobody paired it with anything specific, and nobody said they stopped taking it. Pau d'arco, a smaller ingredient in this product, drew recommendations from a few panelists, while graviola, also a smaller ingredient, got only a neutral mention.
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Dr. Mark Hyman · Cat's Claw · recommends
- Mentions cat's claw as a well-known anchor in herbal anti-tick borne infection protocols.
- Mentions Uncaria tomentosa, also known as cat's claw, as one of 50 extraordinary NRF2 activators found in the Amazon that promote longevity, but notes they are difficult to obtain in the West due to quality and dosing concerns.
- Intuitively takes Cat's Claw, believing their body needs it to block inflammation and keep their brain clear, based on their genomics.
- Mentions cat's claw as one of the top herbs found to be effective in a recent paper on botanicals for Lyme disease.
- Recommends certain teas like Pau d'arco bark tea, which contains beta-lapachones, for increasing NAD levels.
Siim Land · Cat's Claw · neutral
- Mentions Cat's Claw, also known as AC-11, as a tropical plant that helps get rid of CPDs, which are formed when DNA is melted together by UV radiation.
Dr. Eric Berg · Cat's Claw · recommends
- Dr. Berg states that cat's claw plant is one of the best remedies for mycoplasma.
- Recommends pau d'arco as a very powerful herb to consider for certain issues.
- Lists cats claw as a new remedy for rheumatoid arthritis.
- Recommends Cat's Claw as a natural remedy for autoimmune conditions, noting its antioxidant, anti-inflammatory, and antimicrobial properties, and its ability to build up defenses without meds.
Dave Asprey · Cat's Claw · neutral
- Lists Cat's Claw as one of the things that affect and modulate IL-6.
Ben Greenfield · Cat's Claw · uses
- Reintegrates Cat's Claw as a regular part of his rotation to keep the blood clean and impact Epstein-Barr.
- Mentions soursop or graviola as being popular for its anti-cancer benefits.
- Ben mentions Pau D'arco as a stem cell mobilization compound in a formula.
- Mentions Pau d' Arco powdered tea as part of Dr. Mercola's autophagy tea.
- Ben recommends Pau d'Arco as part of a combo to increase cellular autophagy.
- Uses Pau d'Arco powder, derived from tree bark, as part of a specialty powder blend taken before bed to increase NAD production, mitochondrial health, and antioxidant activity while sleeping.
- Mentions Pau d'Arco as part of a nighttime autophagy powder.
- Takes Pau d'arco at night as part of an autophagy mimicking stack.
- Lists Pau d'arco bark tea as an advanced biohacking practice.
- Recommends Pau d'Arco bark tea for mitochondrial support, noting it has a similar effect to other mitochondrial supplements.
- Uses 1 teaspoon of Pau d' Arco powdered tea as part of his 'autophagy tea' before his nightly fast.
- Includes pau d'arco bark in their autophagy tea to upregulate autophagy or increase NAD+.
RAL Summary
Members OnlyTier 4 for Focus and Memory
The review summary describes store service and other products such as ParActin, a melasma product, eye-pressure pills and a Bacillus subtilis product, not this Amazonian formula, so the reviews and the 28-review count should be set aside. Its reviews are set aside, so it is graded on its studies alone. Animal studies support Cat's Claw, but there are not yet enough reviews to confirm it (0).
- Emerging: not enough evidence to rank higher yet.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Nervous system
Combine with: For cognitive support, pair it with omega-3 DHA/EPA for neuronal membrane health, a bioavailable B-complex (methylfolate, B12, B6) for neurotransmitter synthesis, and L-theanine to smooth out stimulant effects and reduce jitters. Citicoline or alpha-GPC can add cholinergic support, and magnesium (threonate or glycinate) supports calm focus and sleep quality. If the real goal is cellular and DNA repair, consider adding NMN or NR with trans-resveratrol, plus PQQ, CoQ10 or ubiquinol, and alpha-lipoic acid, in addition to a diet rich in polyphenols. Check with a clinician first, especially if you take medications or have heart or blood pressure concerns, since stimulant herbs can interact.
Possible side effects: No major side effects reported.
Supplement Facts
Suma root extract 400 mg · Cat's Claw Bark Extract 400 mg · Graviola leaf extract 400 mg
| Suma root extract | 400 mg | † |
| Cat's Claw Bark Extract | 400 mg | † |
| Graviola leaf extract | 400 mg | † |
| Pau d'Arco Root Extract | 300 mg | † |
| Mullaca, Powder | 300 mg | † |
Other ingredients: Acacia Gum, White Rice Flour.
Directions: Recommended use: Adults. Take 2 capsules twice a day.
Barcode (UPC) 05453003827894 · Label source: NIH label database · Report a label change
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Graded November 3, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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