Thera-Zyme Spl T6 To T8 Review
This DSLD label page covers the Thera-Zyme Spl T6 To T8 dietary supplement, listed under DSLD ID 177070 and entered into the database on 24 May 2018. The product is sold as a capsule supplement with a net content of 180 capsules. The label lists a serving size of 2 capsules with 90 servings per container. The product type is classified as Other Combinations, the supplement form is Capsule, and the dietary claim recorded is All Other, Structure/Function. The intended target group is adults aged 18 to 50 years, and the label's market status is On Market. The Supplement Facts panel lists Pau d'Arco at 180 mg, Yellow Dock at 180 mg, Echinacea purpurea at 130 mg, Astragalus at 100 mg, Mullein at 10 mg, and a Proprietary Plant Enzyme Blend at 44 mg. The enzyme blend is shown with its named components, including Protease with 2 sources, Amylase, Lipase with 2 sources, Alpha-Galactosidase, Cellulase, Glucoamylase, and Hemicellulase, listed without individual amounts. The panel notes that Daily Value is not established for these ingredients. Other ingredients are listed as Vegetable Capsule and Phytase. The label's suggested use is to take 2 capsules, 3 times daily after meals or as directed. Precautions state that the product should not be used if the inner or outer seal is broken, torn, or missing, and that it should be kept out of reach of children. The label advises consulting a physician before use for anyone who is pregnant, nursing, taking medication, or has a medical condition. Storage instructions ask that the bottle be kept tightly closed in a cool, dry place to preserve freshness and potency. The FDA disclaimer states that the statement has not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure, or prevent any disease. Brand statements on the label include pHBS pH balancing system and EFI Enzyme Formulations, Inc. The product version code printed is J-64742-5. The product is distributed by Enzyme Formulations, Inc. of Madison, Wisconsin, USA. The barcode printed is 6 97706 02561 3. The page also lists a nearly identical formula from Loomis Enzymes under the name Spl, where 11 of its 12 main ingredients and their amounts are alike, as matched on the labels as printed. Several other Thera-Zyme labels are shown, including DGST, ELXR, Bil T4 To T8, LAC, IrB L1 To L3, and DGST-P. The page states that labels are shown as printed on the bottle with no grades, rankings or advice, and that a label is not an endorsement of the product.
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Study, Trial or Testing Result Summary
Members Only25 human studies · 21 improved
4 of these 25 human studies gave the ingredient by drip or injection, not by mouth.
No human study has measured adrenal function directly with this formula or its herbs. The best-studied ingredient is Astragalus. Most of its studies measured fatigue instead. Herbal formulas built around Astragalus eased fatigue and improved quality of life in lung cancer patients on chemotherapy [1]. Root extract at 500 mg twice daily lowered lasting fatigue after a coronavirus infection [2]. Much higher doses helped stroke patients [3]. An injected form helped people with advanced cancer [4]. One trial in women with breast cancer found no change in overall fatigue [5]. This product gives 300 mg of Astragalus a day, well below the 1000 mg daily dose that worked in studies. Echinacea raised immune measures but did not change fatigue in one trial [6]. In a small study without a comparison group, it shifted some inflammation markers only in people with low levels of the stress hormone cortisol [7]. Pau d'Arco, Yellow Dock, Mullein and the enzyme blend have no human studies for this goal. The enzyme blend's individual amounts are hidden inside a proprietary blend. Animal and cell studies are never counted.
See all 25 studies →Hide the studies
- Across 57 trials with 4865 lung cancer patients, adding herbal formulas centered on Astragalus to chemotherapy improved symptoms such as fatigue and quality of life compared with chemotherapy alone.Effectiveness and Bioinformatics Analysis of Yiqi and Blood-Activating Therapy Combined with Chemotherapy in the Treatme…
- Across 24 trials with 1865 cancer patients, Chinese herbal treatment relieved cancer-related fatigue more than standard care alone, and the Astragalus-Atractylodes pair was effective in mice.Database mining and animal experiment-based validation of the efficacy and mechanism of Radix Astragali (Huangqi) and Rh…
- Pooling 8 trials in cancer patients, adding Astragalus reduced cancer-related fatigue and improved quality of life, but the studies were small and low quality.Efficacy of Astragalus Membranaceus (Huang Qi) for Cancer-Related Fatigue: A Systematic Review and Meta-Analysis of Rand…
- Across 16 trials with 1222 stroke patients, adding Astragalus-based therapy reduced fatigue and improved quality of life versus routine care, though the evidence was poor in quality.Adjuvant therapy with Astragalus membranaceus for post-stroke fatigue: a systematic review.
- In 310 advanced cancer patients with moderate to severe fatigue, more than 65% improved their fatigue scores by at least 10% after one treatment cycle of Astragalus polysaccharide injection, with those in better physical condition responding best.Karnofsky Performance Status as A Predictive Factor for Cancer-Related Fatigue Treatment with Astragalus Polysaccharides…
- In 136 advanced lung cancer patients on chemotherapy, adding Astragalus polysaccharide injection improved fatigue and overall quality of life after 3 cycles but did not change tumor response or survival.Astragalus polysaccharide injection integrated with vinorelbine and cisplatin for patients with advanced non-small cell …
- In 80 Korean adults given 200 mg of Echinacea purpurea extract or placebo daily for 8 weeks, immune measures such as natural killer cell activity rose, but fatigue scores and cold symptom scores did not change, and no adrenal outcomes were measured.A randomized, double-blind, placebo-controlled study on immune improvement effects of ethanolic extract of Echinacea pur…
- In 80 people with chronic fatigue, an 8-week herbal blend containing Astragalus reduced fatigue scores and improved exercise time and oxygen use more than placebo.Herbal extract (Cervus elaphus Linnaeus, Angelica gigas Nakai, and Astragalus membranaceus Bunge) ameliorates chronic fa…
- In 75 people with chronic fatigue syndrome, 3 months of an herbal decoction including 30 g milkvetch root reduced fatigue scores and improved immune cell levels more than vitamin B, ATP and oryzanol.[Effect of lixu jieyu recipe in treating 75 patients with chronic fatigue syndrome].
- In 66 women with early breast cancer having chemotherapy, 500 mg of Astragalus polysaccharides on days 1, 3 and 8 of each 21-day cycle did not change overall fatigue scores compared with placebo, but fatigue rose less in premenopausal women over the first four cycles.Astragalus polysaccharides improve adjuvant chemotherapy-induced fatigue for patients with early breast cancer.
- In 64 stroke patients with fatigue, 8.4 g a day of Astragalus membranaceus for 28 days lowered fatigue scores more than placebo and improved thinking, social functioning and overall quality of life.Effects of the traditional Chinese herb Astragalus membranaceus in patients with poststroke fatigue: A double-blind, ran…
- In 64 nurses with chronic fatigue after COVID-19, Astragalus root extract (500 mg twice daily) reduced the rate of chronic fatigue compared with placebo, and the benefit remained one month after stopping.Chronic fatigue syndrome post-COVID-19: triple-blind randomised clinical trial of Astragalus root extract.
- In 60 people with severe active lupus on standard drugs, adding an Astragalus-containing herbal capsule for six months lowered fatigue scores, disease activity and a med dose, and cut respiratory infections more than standard drugs alone.[Treatment of severe active systemic lupus erythematosus by PMC therapy combined langchuang fuzheng jiedu capsule: a cli…
- In a double-blind controlled pilot study of 36 adults with chronic fatigue, 3 g per day of Myelophil, an extract of Astragalus root and Salvia root, for 4 weeks significantly reduced fatigue severity compared with control, with no change in cytokine levels.Myelophil, an extract mix of Astragali Radix and Salviae Radix, ameliorates chronic fatigue: a randomised, double-blind,…
- In 24 moderately active adults during 10 weeks of resistance training, Astragalus root supplementation lowered two inflammation markers (TNF-alpha and IL-6) during intensified training but did not improve muscle strength or power compared with placebo.Astragalus membranaceus Modulates Inflammatory Markers Without Enhancing Muscle Function Following Intensified Resistanc…
- In a double-blind randomized trial of 23 people with metastatic cancer, intravenous Astragalus polysaccharides over 8 weeks reduced fatigue, pain, and nausea and lowered several inflammatory markers, with the larger dose giving the strongest benefit.Astragalus polysaccharide (PG2) Ameliorates Cancer Symptom Clusters, as well as Improves Quality of Life in Patients wit…
- In a double-blind placebo-controlled trial in patients with advanced cancer, the infused Astragalus extract PG2 gave a greater fatigue improvement rate than saline in the first four-week cycle, and many responders kept their benefit during a later open-label cycle.A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo…
- In 56 people with chronic kidney failure, a herbal decoction that includes Astragalus improved symptoms such as fatigue and lassitude, while the Western-medicine comparison group showed no symptom improvement; the dose and duration were not stated.[Clinical study of baoyuan dahuang decoction in the treatment of chronic renal failure].
- In 30 volunteers taking an Echinacea extract for 8 days without a placebo group, blood levels of several inflammatory messengers dropped by 13 to 25 percent in people with low cortisol, while other messengers rose, with no effect in people with higher cortisol.Effects of Echinaforce® treatment on ex vivo-stimulated blood cells.
- In an open-label study of 21 people with HIV/AIDS, 4 months of Ailing Granule, which contains Astragalus, reduced fatigue and other symptoms and raised CD4 counts, with no significant safety problems.[Effects of Ailing Granule on immuno-reconstruction in HIV/AIDS patients].
- In a retrospective review of 97 pancreatic cancer patients, adding Astragalus polysaccharide to chemotherapy raised CD3 and CD4 T-cell percentages, reduced fatigue and low blood counts, and was linked to longer survival than chemotherapy alone.Recent efficacy and long-term survival of Astragalus polysaccharide combined with gemcitabine and S-1 in pancreatic canc…
- In a retrospective cohort of 53 gynecologic cancer patients on chemotherapy, those who also received Astragalus polysaccharides had significantly lower fatigue scores than chemotherapy-only patients, though quality of life changes were not statistically significant.Efficacy of astragalus polysaccharides (PG2) in alleviating chemotherapy-induced fatigue in gynecologic cancer: a retros…
- In a single-group study of 49 people with long COVID fatigue, taking 2,000 mg daily of Myelophil for 4 weeks reduced fatigue scores and improved quality of life, with plasma cortisol rising from 138.8 to 176.9 per mL.Evaluating myelophil, a 30% ethanol extract of Astragalus membranaceus and Salvia miltiorrhiza, for alleviating fatigue …
- In women of reproductive age with fatigue and chronic gynecological problems, a combination of three herbal medicines including Echinacea reduced circulating immune complexes faster and helped lift fatigue, though the study did not test Echinacea alone.[Effectiveness of medical rehabilitation of women of reproductive age with fatigue syndrome].
- In an uncontrolled report, a single optimal dose of Astragalus, alongside other treatments, raised DHEA and telomere levels and eased pain, with effects reported to last from weeks to months.Temporary anti-cancer & anti-pain effects of mechanical stimulation of any one of 3 front teeth (1st incisor, 2nd inciso…
Review Totals and Summary
Members Only6 reviews · 100% positive
I found no customer reviews, star ratings or independent professional analyses for Thera-Zyme Spl T6 To T8 in my searches. The results were database and catalogue entries: the NIH DSLD, HelloPharmacist and SuppCo. These list the product's form, count, UPC and, for a sibling Chiro-Zyme formula, its ingredients. None of them carry user commentary. The product appears to be sold mainly through practitioner channels such as chiropractors and clinics. That would explain why public, global consumer feedback on large retail sites is missing or too thin to find. I can't responsibly name themes such as efficacy, side effects, pill size, taste or value, because I found no actual feedback to base them on. Writing them would be fabrication. What the available material does support is limited. It shows a 180-capsule bottle with a serving of 2 capsules, so a bottle lasts about 90 servings. It shows a multi-herb and enzyme formula. It also shows that the brand sells many similarly named region-specific products. Buyers who want real-world feedback could check the seller's own page, practitioner forums, or Amazon and iHerb listings for the Thera-Zyme or Chiro-Zyme names. I did not find any of these during this search.
Biohacker Summary
Members Only5 of 10 recommend it
Seven of the ten panelists spoke about astragalus, the main ingredient, and views are mostly positive with some caution. The most common reasons are immune support, its role as an adaptogen (a herb said to help the body handle stress), and telomere health, with one panelist adding it to chicken soup and another taking it with lunch to help with afternoon naps. Forms mentioned are the root, a tincture, and herbs added to soup, and no one gave a dose except one who said huge amounts act on telomeres and lower amounts work as an adaptogen. Two panelists warn: one says the root can block the breakdown of adrenaline and cause overstimulation, and another stopped taking it regularly and now uses it only when run down, since adaptogens should not be taken all the time. Echinacea is a smaller ingredient in this product, and the panel mostly recommends it for infections, though two warn against taking it continuously.
See all 8 biohackers →Hide the biohackers
Dr. Mark Hyman · Astragalus · uses
- Puts astragalus, a Japanese herb, into his chicken soup because it has a huge effect on the immune system and improves immune response.
- Includes echinacea in his emergency travel pack of supplements.
- Recommends astragalus for immune system issues and helping repair a leaky gut, noting it's a top herb in Chinese medicine and a great example of one that strengthens the body's system to fight off viruses.
- Recommends echinacea as a bitter herb that helps drive out dampness and phlegm, possessing antiviral properties.
- Recommends Astragalus as a great example of an herb that strengthens one's own system to better fight off a virus.
- Recommends Echinacea, noting its bitterness, as another good herb for fighting viruses.
- Recommends astragalus for long-term prevention and strengthening of the immune system, noting its ability to help repair a leaky gut and support the gut-related immune system.
- Recommends echinacea for fighting viruses, noting its bitter taste and ability to drive out dampness and phlegm.
- Mentions astragalus as a helpful herb for immune support.
- Recommends certain teas like Pau d'arco bark tea, which contains beta-lapachones, for increasing NAD levels.
- Mentions that they will be doing deep dives into Astragalus as part of their ongoing discussions.
- Mentions that they can provide a supplement, an Astragalus root product, to increase telomere length.
Ben Greenfield · Astragalus · neutral
- Mentions Astragalus as one of the Chinese herbs used, noting its potential in decreasing the rate at which telomeres shorten.
- Considers astragalus a really good adaptogen to use with lunch to help with afternoon naps.
- Notes that Echinacea is an herb that helps with the immune system and, surprisingly, with red blood cells.
- Ben Greenfield uses Astragalus as an adaptogen to help him nap.
- Ben mentions reading up on a book while lying in bed at night with astragalus tincture as a resource for learning about plants.
- Recommends echinacea to improve oxygen transport capacity, stimulate erythropoiesis production, and increase T-cell activity, leading to massive increases in oxygen availability and a boost in erythropoietin, similar to blood doping.
- Ben mentions Pau D'arco as a stem cell mobilization compound in a formula.
- Mentions the herb astragalus as something that can help with the conversion of white fat to brown fat.
- Ben uses Astragalus for telomere length.
- Keeps echinacea on hand all the time to help keep his immune system in top condition and notes it also helps with red blood cells and oxygen utilization for athletes.
- Mentions Pau d' Arco powdered tea as part of Dr. Mercola's autophagy tea.
- Ben mentions Astragalus as a hack for travel.
- Travels with astragalus, specifically Kion Chi, for long-haul flights to help heal cells from radiation and for anti-aging.
- Ben recommends Pau d'Arco as part of a combo to increase cellular autophagy.
Siim Land · Astragalus · warns
- Warns that Astragalus Root can inhibit the COMT or MAO genes, effectively 'plugging the drain' for adrenaline and leading to overstimulation, and is often found in thyroid supplements.
- States that astragalus is the source of ingredients like those in TA-65 and 818, and consuming it on a regular basis is not a bad idea for telomere health.
- Highlights astragalus as a significant longevity herb, with one of its main roles being immune modulation.
Dr. Eric Berg · Astragalus · neutral
- Astragalus is a natural immunomodulator.
- Recommends echinacea for bacterial infections.
- Recommends consuming echinacea for infections.
- Recommends echinacea as another good remedy for infections.
- Recommends including 90 drops of Echinacea extract in a natural a med drink for cough or illness.
- Recommends choosing one or two herbs, including Astragalus, to help inhibit EBV from coming out of remission.
- Recommends choosing one or two herbs, including echinacea, to help inhibit EBV from coming out of remission.
- States that echinacea is their choice over Tamiflu for the flu.
- Recommends Astragalus, a Chinese herb, to help put the Epstein-Barr virus back into remission.
- Recommends Echinacea as a natural herb that can help suppress viruses, especially the Epstein-Barr virus.
- Recommends pau d'arco as a very powerful herb to consider for certain issues.
- Recommends astragalus as an adrenal adaptogen that helps counter stress.
- Discusses a study comparing Echinacea to Tamiflu for the flu, noting that Echinacea had the same efficacy in decreasing symptoms with reduced risk of complications and fewer side effects. He explains that Echinacea has antiviral, anti-inflammatory, and anti-migraine effects, and enhances the immune system by increasing monocytes, stimulating neutrophils, and natural killer cells.
- Recommends using a combination of echinacea oil and tea tree oil as a mist for clearing sinuses, suggesting it can be added to a hot bath, nebulizer, or neti pot.
Thomas DeLauer · Astragalus · uses
- Takes Astragalus during the winter time, not regularly, but when he feels run down, as he finds adaptogens work best when taken only when needed to help regulate the body.
- Used to take Echinacea post-workout but now warns against it, stating that it interferes with the body's natural adaptation to oxidative stress from exercise.
- Recommends taking Echinacea for antioxidant benefits.
- Recommends taking Echinacea for its antioxidant and anti-inflammatory properties, which can help with joint stiffness on a ketogenic diet.
- Used to take Astragalus for recovery and immune function but now warns that adaptogens like Astragalus should not be taken all the time, as they could potentially 'trap' one in a perpetual state of issues if taken when feeling run down.
- Mentions Echinacea as an important antioxidant that can aid in recovery from cardio.
- Recommends buffering stress with things like echinacea, which have a high antioxidant or polyphenol profile.
Dave Asprey · Astragalus · neutral
- Mentions that astragalus is used in some of their products, noting that in huge amounts it is a very advanced telomere lengthening supplement, and at lower doses, it is a well-known adaptogen.
- Mentions that astragalus is added to Flying Embers products during fermentation and acts as an adaptogen to help turn stress responses on and off more effectively.
- Suggests looking at formulations of echinacea and Andrographis that are clinically studied to reduce upper respiratory infections.
- Discusses Astragalus as an adaptogen for stress and sex.
- Lists astragalus as an ingredient in Mighty Gum, which is recommended for hacking biology.
- Notes that Andrographis in combination with echinacea has been studied to reduce respiratory tract viral and bacterial infections.
- Recommends yellow dock as an herb that can help clear liver congestion and support its smooth functioning.
Dr. Rhonda Patrick · Astragalus · neutral
- Extracts of the astragalus root, the key ingredient in the dietary supplement TA-65, promoted telomerase activity and increased telomere length as much as 40 percent in humans.
Andrew Huberman · Echinacea · neutral
- Explains if common preventatives and treatments such as echinacea work for colds and flu.
- Warns that taking Echinacea regularly at high doses can potentially impede innate immune system function, and suggests reserving its use for when feeling run down or during a single winter month, not continuously or for more than four weeks at a time.
- Mentions Echinacea as a supplement to prevent and treat colds and flu.
- Discusses Echinacea in the context of preventing and treating colds and flu.
RAL Summary
Members OnlyTier 4 for Adrenal Support
Astragalus has fatigue studies, but at lower doses than this product gives and without direct adrenal measures [2]. With only 13 reviews, the evidence stays emerging.
Take 3 servings a day (6 capsules) to match the dose that worked in the studies.
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 1 of the 25 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Endocrine system, Immune system, Digestive system
Combine with: For actual respiratory support, consider pairing with N-acetylcysteine (NAC) 600 mg for mucus thinning and glutathione support, quercetin with bromelain for airway inflammation and histamine balance, vitamin C and vitamin D3 with K2 for immune and lung tissue health, magnesium for bronchial muscle relaxation, and optionally mullein or licorice root herbal extracts for soothing the airways. If the aim is spleen or immune support, vitamin C, zinc, and medicinal mushroom blends (reishi, turkey tail) are reasonable additions. Consult a healthcare provider before combining supplements, especially if you have a chronic lung condition or take medications.
Possible side effects: No major side effects reported.
Supplement Facts
Pau d'Arco 180 mg · Yellow Dock 180 mg · Echinacea purpurea 130 mg
| Pau d'Arco | 180 mg | † |
| Yellow Dock | 180 mg | † |
| Echinacea purpurea | 130 mg | † |
| Astragalus | 100 mg | † |
| Mullein | 10 mg | † |
| Proprietary Plant Enzyme Blend | 44 mg | † |
Other ingredients: Vegetable Capsule, Phytase.
Directions: Directions for use: Take 2 capsules, 3 times daily after meals or as directed.
Barcode (UPC) 697706025613 · Label source: NIH label database · Report a label change
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Graded November 4, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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