Thorne Bacillus Coagulans Review
We don’t sell supplements. We help you make decisions and get the best price.
Lowest prices
Finding the lowest prices at the stores now. This takes a few seconds.
Study, Trial or Testing Result Summary
Members Only16 human studies · 16 improved
Bacillus coagulans is present at a full dose in this product, about 20 billion live organisms a day, well above the 2 billion used in most trials. In 70 adults with gas and bloating, 2 billion spores daily for 4 weeks cut indigestion scores from about 8.9 to 3.1, while placebo barely changed [1]. In 61 adults with gas after meals, 4 weeks of Bacillus coagulans eased abdominal pain and overall digestive symptoms more than placebo, though a strong placebo effect hid other differences [2]. In 68 adults with indigestion, a mix of Bacillus coagulans and Bacillus subtilis helped 48% of people versus 20% on placebo over 8 weeks; that study used a combination, not this probiotic alone [3]. Large pooled reviews of irritable bowel syndrome trials ranked Bacillus coagulans among the best probiotics for abdominal pain and bloating [4][5], and one found it made pain relief about 4.9 times more likely than control [6]. Most of this research is in people with gas, bloating or irritable bowel syndrome rather than upper-belly comfort after meals alone. Animal and cell studies are never counted.
See all 16 studies →Hide the studies
- Pooling 81 trials with 9253 adults with irritable bowel syndrome, two Bacillus coagulans strains ranked among the most effective probiotics for reducing abdominal pain, and one also ranked high for improving stool form in diarrhea-type irritable bowel syndrome.Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review a…
- Pooling 43 trials with 5531 people with irritable bowel syndrome, Bacillus coagulans ranked best among probiotic species for symptom relief, abdominal pain and bloating, with the 8-week use ranking first for pain and straining.Efficacy of Probiotics for Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.
- Pooling 42 trials with 3856 people with irritable bowel syndrome, Bacillus coagulans MTCC5260 made abdominal pain relief about 4.9 times more likely than control.Strain-specific and outcome-specific efficacy of probiotics for the treatment of irritable bowel syndrome: A systematic …
- In 141 children aged 4 to 12 with irritable bowel syndrome, Bacillus coagulans Unique IS2 once daily for 8 weeks reduced pain intensity and abdominal discomfort, bloating and gas more than placebo.Efficacy of Bacillus coagulans Unique IS2 in treatment of irritable bowel syndrome in children: a double blind, randomis…
- In 136 adults with irritable bowel syndrome, 2 billion CFU of Bacillus coagulans Unique IS2 daily for 8 weeks improved abdominal discomfort or pain and bowel movements more than placebo, with no change in inflammation markers.Randomized clinical trial: the effect of probiotic Bacillus coagulans Unique IS2 vs. placebo on the symptoms management …
- In 70 adults with gas and bloating, 2 billion spores of Bacillus coagulans MTCC 5856 daily for 4 weeks cut indigestion scores from 8.91 to 3.06 versus 9.42 to 8.43 with placebo.The effects of Bacillus coagulans MTCC 5856 on functional gas and bloating in adults: A randomized, double-blind, placeb…
- In 68 adults with functional dyspepsia, a Bacillus coagulans and Bacillus subtilis combination twice daily for 8 weeks gave a clinical response in 48% versus 20% with placebo.Efficacy and safety of spore-forming probiotics in the treatment of functional dyspepsia: a pilot randomised, double-bli…
- In 61 adults with gas symptoms after meals, Bacillus coagulans GBI-30 for 4 weeks improved abdominal pain and total digestive symptom scores more than placebo, though a strong placebo effect limited other differences.A prospective, randomized, double-blind, placebo-controlled parallel-group dual site trial to evaluate the effects of a …
- In 60 people with acute diarrhea and abdominal discomfort, Bacillus coagulans LBSC was reported to help recovery from abdominal pain and discomfort and improve quality of life compared with placebo, with no adverse events.A prospective, interventional, randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy and …
- In 60 adults with undiagnosed digestive discomfort, a three-strain Bacillus blend improved dyspepsia scores such as belching, bloating, sour taste and pain more than placebo by day 30 and day 37, with no side effects reported.A prospective, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of…
- In 52 adults with irritable bowel syndrome, a simethicone and Bacillus coagulans combination taken after each meal for 4 weeks reduced bloating and discomfort more than placebo.A randomized double-blind placebo-controlled clinical trial on efficacy and safety of association of simethicone and Bac…
- In a placebo-controlled trial of 44 adults with irritable bowel syndrome, Bacillus coagulans GBI-30, 6086 taken once daily for 8 weeks significantly reduced abdominal pain and bloating scores from baseline.Bacillus coagulans significantly improved abdominal pain and bloating in patients with IBS.
- In a placebo-controlled trial of 40 adults with irritable bowel syndrome, 6 billion Bacillus coagulans LBSC daily for 80 days improved bloating, cramping, abdominal pain and stool consistency more than placebo, with no serious side effects.Efficacy and safety of Bacillus coagulans LBSC in irritable bowel syndrome: A prospective, interventional, randomized, d…
- In a placebo-controlled trial of 36 adults with diarrhea-predominant irritable bowel syndrome, 2 billion CFU of Bacillus coagulans MTCC 5856 daily for 90 days reduced bloating, abdominal pain, diarrhea and stool frequency more than placebo and improved quality of life.Bacillus coagulans MTCC 5856 supplementation in the management of diarrhea predominant Irritable Bowel Syndrome: a doubl…
- In 50 people with diarrhea-predominant irritable bowel syndrome, 2 billion CFU of Bacillus coagulans daily for about 8 weeks reduced abdominal pain, bloating, diarrhea and stool frequency compared with placebo.The role of Weizmannia (Bacillus) coagulans LMG S-31876 in treating IBS-diarrhea.
- In 50 older adults with indigestion, a Bacillus coagulans and digestive enzyme syrup taken for 5 days improved dyspepsia scores more than the control syrup in an open-label trial, with good tolerability.A prospective, randomized, open-label, placebo-controlled comparative study of Bacillus coagulans GBI-30,6086 with diges…
Review Totals and Summary
Members OnlyWhat buyers say
No written reviews read yet.
Biohacker Summary
Members Only0 of 10 recommend it
Five of the ten panelists spoke about Bacillus coagulans, and the group leans positive: two recommend it, one uses it, and two are neutral. One panelist recommends a shelf-stable, spore-based form, calling it well studied for bloating, bowel trouble and sleep, and also describes it as a soil-based organism that calms inflammation and encourages friendly gut bacteria. Another uses it as one of the strains in a homemade yogurt to help control gut overgrowth, and has also used it as a binder in a detox plan. A third recommends a specific strain in a bar and calls it a heavily researched blend, while the neutral voices only note that it forms spores and that kombucha contains it. No one gave a dose, no one named a supplement to pair it with beyond yogurt and other probiotics, and no one reported a caution or said they stopped taking it.
See all 5 biohackers →Hide the biohackers
Ben Greenfield · Bacillus Coagulans · uses
- Uses B. coagulans as one of the bacterial strains in his homemade SIBO yogurt to help control SIBO.
- He uses bacillus coagulans as a binder to help remove compounds from the body as part of the body phase of his detox protocol.
Dr. Mark Hyman · Bacillus Coagulans · recommends
- Recommends Lactospore, a shelf-stable, spore-based probiotic (Bacillus coagulans) that has been well-studied and shown to significantly reduce bloating, irritable bowel, vomiting, diarrhea, pain, depression, and improve sleep and quality of life.
- Mentions bacillus coagulans as another soil-based organism that has been shown in clinical studies to be anti-inflammatory and encourage the growth of beneficial bacteria.
- Recommends Bacillus coagulans as a soil-based organism that has been shown in clinical studies to be anti-inflammatory and encourage the growth of beneficial gut bacteria.
- Recommends bacillus coagulans, a soil-based organism, as a probiotic that has been shown in clinical studies to be anti-inflammatory and encourage the growth of F. prausnitzii.
Dave Asprey · Bacillus Coagulans · neutral
- Mentions that Bacillus Coagulans is a spore former that maintains its integrity in an aqueous format and helps get the product fully dry, aiding in the fermentation process.
- Dave Asprey takes the Just Thrive Health probiotic because it contains bacillus indicus HU36, which makes compounds beneficial for eye health, and he believes doing both the probiotic and separate supplements is the right approach.
Thomas DeLauer · Bacillus Coagulans · recommends
- Highlights the inclusion of Bacillus coagulans SNZ 1969 in the Redd Bar, calling it a 'heavily researched blend' of probiotics.
Dr. Eric Berg · Bacillus Coagulans · neutral
- Dr. Berg mentions that kombucha provides Bacillus coagulans.
RAL Summary
Members OnlyTier 4 for After-Meal Comfort: Long-Term Relief
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Digestive system
Possible side effects: No major side effects reported.
Supplement Facts
Bacillus coagulans 133 mg
| Bacillus coagulans | 133 mg | † |
Other ingredients: Microcrystalline Cellulose, delayed-release Capsules, Medium Chain Triglyceride.
Directions: Suggested use: Take 1 capsule two to three times daily or as recommended by your health-care practitioner.
Barcode (UPC) 693749758020 · Label source: NIH label database · Report a label change
Show entire label
More after-meal comfort: long-term relief products
Members OnlyThe highest ranked for the same goal
Graded November 5, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
Privacy policyConsumer health dataTermsDo Not Sell or Share My Personal InformationCookie settings



