Thorne Ferrasorb Review

Advanced Iron Complex is presented on this Thorne page as a capsule that supplies iron, essential B vitamins and vitamin C for comprehensive nutritional support for iron-deficiency anemia. The page states that the product provides iron in chelated form for optimal absorption, with vitamin C included to enhance iron's absorption, plus the active forms of folate and vitamins B6 and B12. Each capsule provides 36 mg of elemental iron as Ferrochel chelate. The page explains that iron is essential to the formation and function of healthy red blood cells, and that an adequate amount of iron in the diet is required for blood cells to efficiently transport oxygen throughout the body. It cites the U.S. Centers for Disease Control, noting that up to 16 percent of individuals in certain populations are deficient in iron. Listed features include reduced GI side effects such as nausea and constipation, and active forms of vitamins B12, B6 and folate with vitamin C for an enhanced approach to red blood cell health. The page lists who may benefit, including individuals looking for nutritional support for anemia, women of menstruating age, individuals who follow a vegan or vegetarian diet, older individuals who tend to have less stomach acid, individuals who have undergone gastric bypass surgery, those with intestinal conditions that affect nutrient absorption, and individuals with an autoimmune disorder. Signs of iron deficiency named on the page include fatigue or weakness, shortness of breath, pale skin, cold hands and feet, feeling lightheaded or dizzy, changes in menstrual cycles and decreased athletic performance. The page notes that iron is difficult for the body to absorb and that conventional forms such as ferrous sulfate can cause gastrointestinal side effects including nausea, vomiting, constipation, diarrhea and dark-colored stools. Thorne states that this product contains iron reacted with glycine to enhance absorption and help decrease those typical side effects. The page also explains the reason for the B vitamins: a deficiency in them can lead to adverse issues with red blood cell formation, and signs named include fatigue or muscle weakness, decreased mood quality, sores in the mouth or on the tongue, problems with memory or cognition, and a feeling of being on pins and needles. The product is described as combining the active forms of vitamin B6 as pyridoxal 5'-phosphate, vitamin B12 as methylcobalamin and folate as L-5-methyltetrahydrofolate, along with vitamin C and a well-absorbed form of iron. Thorne describes the formula as made with the scientific rigor the brand is known for, with ingredients selected, clinically studied and tested through multiple rounds of quality control. The page states the product has been third-party tested and certified to verify that what is in the package matches the label and that it contains no unsafe levels of contaminants such as heavy metals, pesticides and microorganisms. The warnings section adds that the product is contraindicated in anyone with a history of hypersensitivity to its ingredients, that pregnant people should consult a health-care practitioner before use, and that 5-MTHF is not recommended concurrent with a med cancer therapy. It also warns that accidental iron overdose is a leading cause of fatal poisoning in children under six and that the product should be kept out of reach of children.

Product Focus: EnergyAlso covers:BrainDigestion
Tier ⓘ
Tier 2 · Rank 5
Tier 2 · Researched. Human studies show improvement in an aging-related function or a specific goal, and the reviews agree. Rank 5 within Tier 2 for Energy; 5 of 83 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
86 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
89% of 312
Biohacker Mentions
10 of 10

Study, Trial or Testing Result Summary

Members Only132 human studies · 62 improved

34 of these 132 human studies gave the ingredient by drip or injection, not by mouth.

132 human studies62 improved54 no effect62,160 people studied

Iron is the main ingredient here, at a full dose of three capsules a day. Iron reduces tiredness mainly in people who are low in iron. A review of 18 trials in iron-deficient adults found less fatigue, but no better measured fitness [1]. Another review found that iron reduced fatigue in people without anemia, but the benefit disappeared when people with normal iron were included [2]. In 198 menstruating women with low iron stores, 80 milligrams daily for 12 weeks reduced fatigue more than placebo [3]. An iron infusion reduced fatigue in 65.3% of tired, iron-deficient women versus 52.7% on placebo [4]. Vitamin B6 reaches a full dose at three capsules a day, but large trials of blends containing it found no energy benefit [5][6]. Vitamin C here is below the studied dose. It helped mainly people whose vitamin C was low [7]. Vitamin B12 did not boost energy in people who were not deficient [8][9]. Adding folic acid to iron did not change fatigue in women with anemia after childbirth [10]. Expect benefit mostly if you are low in iron. Animal and cell studies are never counted.

See all 132 studies →Hide the studies

Review Totals and Summary

Members Only312 reviews · 89% positive
312 reviews · Thorne 312
89% positive2% neutral9% negative

Thorne's page shows 312 ratings in total, and the themes below come from the written reviews that could be read on that page, which were five short reviews from verified buyers. Reviews of other forms of the product were not part of this, and only the capsules are covered. What buyers praise most is the combination of ingredients in a single capsule. Michelle R. likes that vitamin C is included to increase absorption, and that B12 is also included so she does not need an additional pill. The most specific outcome comes from Kathleen S., who had low ferritin before starting and says it is now back up to normal. Carol M. says it has been great and plans to order again. Jewell W. and Sarah B. left brief positive comments, "Excellent" and "Really good product," without saying what they liked or how it worked for them. The page also carries its own AI-generated summary, labelled as produced from customer reviews. It says the product, formerly known as Ferrasorb, is praised for enhancing iron absorption and providing comprehensive nutritional support for anemia, and that customers report feeling better and more energetic. The popular topic tags on the page point the same way, with recurring words such as results, quality, feel and improvement. On the complaint side, the same AI summary says some people experience constipation or stomach issues, and "issues" and "stomach" also appear among the topic tags. None of the five visible written reviews mentions constipation or stomach problems, so those complaints rest on the summary text and tags, not on any review a reader can see. Beyond that, no complaints appear in the readable reviews. As for who it seems to suit, the feedback points to people managing low iron or anemia, such as the reviewer whose ferritin returned to normal, and to people who want iron, vitamin C and B12 in one capsule instead of taking separate pills. Repeat purchase is mentioned once, by Carol M. On form, taste and value, the reviewers say nothing about price in the visible text. None of the five written reviews complains about pill size or taste, but none praises them either, so nothing can be said about either point. Overall, the five written reviews are all positive, but only a few give detail: the convenience of the combined formula and one reported return of ferritin to normal. Five written comments against 312 ratings is a small sample of the written feedback, so the star distribution on the page is the better guide to overall satisfaction. The stomach and constipation concern is worth keeping in mind, since it appears in the page's summary even though no readable review describes it.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

The panel is split on iron, the main ingredient: three of ten recommend it, one uses it, four are neutral, two warn about it, and one stopped. Those who recommend it point to brain function and dementia risk, keeping muscle, and women of reproductive age who are low in iron, and one panelist said testing first and replenishing only if levels are low makes sense. One panelist said they got less sore in training after starting an iron supplement, while another had low iron for 11 years and found no form of supplement raised it, so they stopped. The cautions are that too much iron may increase aging cells that drive inflammation, and that a diagnosis of anemia does not always mean you need more iron. Vitamin C, folate and vitamin B12 are smaller ingredients in this product, and the panel mostly speaks well of vitamin C, mainly for collagen.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Iron · neutral
    • 30 Oct 2026 · neutral · YouTube ↗
      Identifies iron as the Achilles' heel of cancer, as it is needed for its DNA to replicate.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
    • 25 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Dr. Berg states that Vitamin C helps fight biofilms and is essential for making collagen in gums, teeth, and capillaries.
    • 24 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C as a cofactor, especially for collagen.
    • 23 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that high doses of vitamin C, like 2 to 4 grams, can greatly reduce inflammation and support the immune system.
    • 19 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that birth control pills deplete the body of folate, which is needed for the brain to make serotonin.
    • 18 Oct 2026 · neutral · YouTube ↗
      Mentions that grass-fed liver has heme iron, the most bioavailable form of iron that prevents anemia.
    • 17 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Highly recommends taking natural food vitamin C, about 500 mg, at the first sign of a cold.
    • 10 Oct 2026 · warns · Podcast ↗
      Dr. Berg warns that too much iron can be damaging to the body and advises focusing on food sources to avoid overconsumption.
    • 10 Oct 2026 · Vitamin B6 · warns · Podcast ↗
      Dr. Berg lists pyridoxine hydrochloride as a synthetic vitamin to avoid.
    • 4 Oct 2026 · Vitamin B6 · recommends · Facebook ↗
      Recommends taking the active form of vitamin B6, pyridoxal-5-phosphate (P5P), for its benefits to the nervous system, including building the myelin sheath and protecting sensory nerve integrity.
    • 4 Oct 2026 · Vitamin B6 · neutral · X ↗
      Notes that Vitamin B6 is intimately involved in the nervous system and may be behind sciatica and carpal tunnel syndrome.
    • 4 Oct 2026 · Vitamin B12 · recommends · Facebook ↗
      Recommends taking the natural form of vitamin B12, methylcobalamin, to support nerve regeneration, myelin production, and nerve growth factors.
    • 4 Oct 2026 · Vitamin B12 · neutral · X ↗
      Notes that Vitamin B12 is intimately involved in the nervous system and may be behind sciatica and carpal tunnel syndrome.
  • Dr. Mark Hyman · Iron · neutral
    • 21 Oct 2026 · neutral · YouTube ↗
      Mentions iron as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 21 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that taking folate can lower homocysteine levels, which has shown health benefits and physical improvements in brain scans in clinical trials.
    • 19 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that some people may need a little bit extra folate with a supplement.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 7 Oct 2026 · Vitamin C · neutral · Podcast ↗
      Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
    • 7 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Mentions topical vitamin C as an antioxidant that can help skin with aging.
    • 6 Oct 2026 · Vitamin C · neutral · X ↗
      Mentions that what they do when a cold comes on is not just vitamin C.
    • 5 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends ensuring adequate vitamin C intake on a regular basis for immune support, stating it's important for healthy immune function despite mixed data on its effectiveness for colds.
    • 30 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that vitamin C was the very first vitamin discovered, isolated, and synthesized in 1932, and its deficiency caused scurvy.
    • 14 Sep 2026 · Vitamin C · recommends · Facebook ↗
      Recommends nutrient-dense foods rich in vitamin C, such as guavas and parsley, to reduce inflammation.
    • 9 Sep 2026 · Vitamin C · uses · YouTube ↗
      Used intravenous vitamin C cocktails to help him detoxify and recover from chronic fatigue.
    • 31 Aug 2026 · neutral · YouTube ↗
      Notes that a woman patient had very low iron.
    • 31 Aug 2026 · Folate · uses · YouTube ↗
      Optimized a child's nutrient status with folate, as the child had low folate levels and was not eating greens.
    • 31 Aug 2026 · Vitamin B6 · uses · YouTube ↗
      Optimized a child's nutrient status with vitamin B6, as the child had low B6 levels.
  • Siim Land · Iron · neutral
    • 14 Oct 2026 · neutral · Instagram ↗
      Mentions that iron is a mineral necessary for making collagen.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 30 Sep 2026 · Vitamin C · neutral · X ↗
      Lists sauerkraut and fruit as sources of Vitamin C.
    • 6 Sep 2026 · Vitamin C · neutral · X ↗
      Notes that Vitamin C is one of several supplements with human evidence.
    • 3 Sep 2026 · warns · YouTube ↗
      States that excess iron promotes oxidative stress and inflammation, which increases heart disease risk.
    • 27 Jul 2026 · Vitamin C · neutral · X ↗
      Notes that researchers found vitamin C alleviates ferro-aging, a process of iron overload and lipid peroxidation that drives aging, and that it directly inhibited ACSL4, a protein driving ferro-aging.
    • 27 Jul 2026 · Vitamin C · neutral · X ↗
      States that Vitamin C has a central role in aging and longevity, and that in monkeys, oral vitamin C slowed ovarian aging during a 3.3-year study.
    • 27 Jul 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is one of the most important vitamins for staying healthy and aging well, and that intakes of 200 to 400 mg a day from food or supplements largely saturates plasma and neutrophils in most healthy adults. He also recommends spreading out the vitamin C across the day to avoid oversaturation.
    • 9 Jul 2026 · Vitamin C · neutral · YouTube ↗
      Mentions vitamin C in comparison to topical melatonin for oxidative defense, stating that melatonin would compete but is not as broadly validated clinically.
    • 4 Jul 2026 · Vitamin C · uses · YouTube ↗
      Was found to be vitamin C deficient by True Health and Mayo Clinic tests, and now addresses this by eating one extra kiwi fruit daily.
    • 12 Jun 2026 · Vitamin C · recommends · YouTube ↗
      States that the biggest evidence for multivitamin is that it improves cognition and enhances episodic memory in elderly people, who tend to have worse diets and are more likely to be deficient.
    • 24 Apr 2026 · Vitamin B12 · uses · YouTube ↗
      Created Microvitamin, a supplement that bundled all the supplements he was taking, to help fund his a med trial.
    • 24 Mar 2026 · neutral · YouTube ↗
      Notes that iron deficiency is found in children with premature graying of hair and that some people get gray hair due to iron deficiency.
  • Thomas DeLauer · Iron · neutral
    • 18 Sep 2026 · neutral · Facebook ↗
      Compares iron content in spinach (2.7mg) and beef (2.6mg), but emphasizes that beef's heme iron absorbs at about 25%, while spinach's non-heme iron absorbs at 2-8%.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 18 Oct 2026 · Vitamin B12 · recommends · YouTube ↗
      Recommends Vitamin B12 for mental health and mood, explaining its role in myelination and neurotransmitter production. They specifically recommend a liposomal and micellar form of methylcobalamin B12 for better absorption and to avoid toxicity.
    • 4 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
    • 29 Sep 2026 · Vitamin C · uses · YouTube ↗
      Takes Purity's liquid liposomal vitamin C for immune support and overall wellness, finding it easy to add to water, juice, or take straight up due to its good taste.
    • 18 Sep 2026 · Vitamin C · neutral · Facebook ↗
      Compares the Vitamin C content of oranges (53mg) to guava (228mg), noting guava has 4x more.
    • 29 Aug 2026 · Vitamin C · neutral · Instagram ↗
      States that collagen synthesis is vitamin C dependent, in the context of glowing skin.
    • 25 Aug 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C for sleep, noting that intake in the range of 125 to 200 mg per day is associated with a lower risk of sleep disorders and sleep apnea, with the benefit plateauing beyond this range.
    • 24 Aug 2026 · recommends · YouTube ↗
      Recommends iron from meat, specifically red meat and beef liver, stating that it is a crucial part of the mechanistic triad for thyroid hormone function and is iron-dependent for iodine incorporation into thyroid hormone.
    • 19 Aug 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming a little bit of vitamin C, such as a couple of berries or kiwi, along with flavanol-rich cocoa to help the delicate flavanols hold up and prevent oxidation in the gut.
    • 8 Aug 2026 · Vitamin C · neutral · YouTube ↗
      Explains that vitamin C improves the ability of neutrophils to engulf bacterial infections, and that they have a greater ability to engulf larger infections.
    • 29 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends using a multivitamin to ensure adequate micronutrient intake, especially when wholesome food is less available.
    • 30 Jun 2026 · Vitamin B12 · neutral · YouTube ↗
      Mentions that a single serving of sardines provides vitamin B12 at something like three to four times the daily needs.
  • Andrew Huberman · Iron · recommends
    • 20 Jul 2026 · recommends · YouTube ↗
      States that Iron is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
    • 17 Jun 2026 · Vitamin C · uses · X ↗
      Takes a multivitamin every day for longevity.
    • 2 Feb 2026 · Vitamin C · recommends · YouTube ↗
      Recommends AG1, a vitamin, mineral, and probiotic drink, and notes that for a limited time, a subscription comes with additional supplements.
    • 15 Dec 2025 · Vitamin B12 · neutral · YouTube ↗
      States that a deficiency in vitamin B12 can be terrible and lead to chronic fatigue-like syndromes, as many parts of mitochondria require B vitamins.
    • 30 Oct 2025 · warns · YouTube ↗
      Warns that excess iron will increase the number of senescent cells in the body, which accumulate as people get older and cause inflammation and cancer. He notes that people who are healthy and have a fairly vegetarian diet often have slightly low iron levels but super amounts of energy.
    • 7 Jul 2025 · Vitamin C · uses · YouTube ↗
      Takes an extra gram of vitamin C a day for its effects on immunity and potential synergy with collagen.
    • 16 Jun 2025 · Vitamin C · uses · YouTube ↗
      Found the Met RX Big 100 Bar to be 'magic' on the trail because it's a hunk of calories with protein and fortified with vitamins and minerals, despite being something they would never eat in normal life.
    • 28 Apr 2025 · Vitamin C · uses · YouTube ↗
      Started taking AG1 in 2012 and still takes it every single day to ensure he meets his quota for daily vitamins and minerals and to support gut health, which is critical for proper brain function, immune system, and neurotransmitter production.
    • 14 Apr 2025 · neutral · YouTube ↗
      Notes that about 50% of the population is iron deficient.
    • 31 Mar 2025 · neutral · Instagram ↗
      Mentions that the podcast will review the role of iron in treating depression.
    • 31 Mar 2025 · warns · YouTube ↗
      States that B12, folate, and iron are essential to mitochondrial function and if deficient, mitochondria will not function properly, which is consistent with the mitochondrial theory of neuropsychiatric disorders.
    • 31 Mar 2025 · Folate · recommends · YouTube ↗
      States that B12, folate, and iron are essential to mitochondrial function and if deficient, mitochondria will not function properly, which is consistent with the mitochondrial theory of neuropsychiatric disorders.
    • 3 Feb 2025 · Vitamin C · uses · YouTube ↗
      Has been taking AG1 daily since 2012 because it is the highest quality and most complete foundational nutritional supplement, ensuring he gets all necessary vitamins, minerals, and micronutrients for daily health.
    • 18 Nov 2024 · Vitamin C · uses · YouTube ↗
      Has been drinking AG1 since 2012, finding it difficult to get enough vitamins, minerals, micronutrients, and adaptogens from diet alone. He finds that taking AG1 daily improves all aspects of his health, including physical and mental health, performance, recovery from exercise, and immune system strength, and also notices more mental clarity and energy.
  • Ben Greenfield · Iron · recommends
    • 9 Jul 2026 · recommends · YouTube ↗
      Recommends testing for and replenishing iron if levels are low, as it can affect the ability to maintain or preserve muscle, especially for those on GLP-1s.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 12 Oct 2026 · Folate · recommends · Facebook ↗
      Recommends methylfolate as an active form of folate that the body can use directly without conversion.
    • 24 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
    • 25 Aug 2026 · Vitamin C · neutral · X ↗
      Notes that IV vitamin C has been used for decades for cancer patients with almost no standardization and that he receives many questions about its effectiveness and combination with chemo.
    • 9 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C for skin repair post-tattoo.
    • 9 Jul 2026 · Folate · recommends · YouTube ↗
      Recommends bioavailable folate, not synthetic folic acid, as folate deficiencies seem to impact hearing health in older individuals.
    • 9 Jul 2026 · Vitamin B12 · recommends · YouTube ↗
      Recommends getting vitamin B12 tested and supplementing if deficient, as B12 deficiency can cause damage to the myelin coating around nerves, including cochlear nerves, and improve tinnitus severity scores.
    • 29 May 2026 · neutral · Facebook ↗
      Notes that one can eat iron-rich foods or supplement with iron, but still feel exhausted if iron is not the missing piece, emphasizing that focusing on a single mineral in isolation can support a number on a lab test rather than the system itself.
    • 6 May 2026 · neutral · X ↗
      Mentions iron as a common deficiency.
    • 18 Apr 2026 · Folate · recommends · YouTube ↗
      Recommends introducing methylfolate into the diet to address high homocysteine levels.
    • 16 Apr 2026 · recommends · YouTube ↗
      Recommends a nutritious diet including iron, as it is critical for brain development.
    • 7 Mar 2026 · Vitamin C · warns · YouTube ↗
      Does not agree that ascorbic acid is vitamin C, comparing it to calling chaff wheat, and notes that it is made from genetically modified cornstarch or corn syrup byproducts using solvents.
  • Bryan Johnson · Iron · stopped
    • 8 Jul 2026 · stopped · YouTube ↗
      Has had low iron for 11 years and despite eating meat and trying all forms of iron supplementation at different times and sequences, none of it worked to raise his iron or ferritin levels.
    • 7 Jul 2026 · uses · X ↗
      Had low iron for 11 years, with ferritin averaging 38 ng/mL, and has finally boosted it back to healthy levels.
    • 5 Jun 2025 · Vitamin B12 · uses · YouTube ↗
      States that Blueprint essential capsules and soft gels are packed with key vitamins and minerals needed for strong bone health.
    • 3 Feb 2025 · Vitamin C · neutral · YouTube ↗
      Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
    • 8 Jan 2025 · Vitamin C · uses · YouTube ↗
      Applies vitamin C after showering.
    • 26 Sep 2023 · uses · YouTube ↗
      Takes 10 milligrams of heme iron to get his iron levels up, as they are borderline.
    • 26 Sep 2023 · Vitamin C · uses · YouTube ↗
      Takes 250 milligrams of Vitamin C.
    • Date not recorded · recommends · Website ↗
      Recommends adequate Iron for hair health, noting it is in the Blueprint stack.
    • Date not recorded · recommends · Source ↗
      Recommends supplementing with iron for brain health for both the mother and the baby during pregnancy.
    • Date not recorded · Vitamin C · recommends · Website ↗
      Recommends Vitamin C for skin health, noting it's good to pair with collagen peptides and is included in the Blueprint stack.
    • Date not recorded · Vitamin C · uses · Website ↗
      Bryan Johnson takes Vitamin C daily as part of his Longevity Mix, which is an antioxidant-rich essential vitamin that supports immune function and metabolic energy.
    • Date not recorded · Vitamin C · uses · Website ↗
      He uses Vitamin C, typically in a serum, in the morning for skin health.
    • Date not recorded · Folate · recommends · Source ↗
      Recommends supplementing with folate for brain health for both the mother and the baby during pregnancy.
  • Dave Asprey · Iron · warns
    • 24 Jun 2026 · warns · X ↗
      Warns that if a doctor diagnoses anemia, one should not assume they just need more iron, as low hemoglobin doesn't always mean low iron and the issue can sometimes be how well the body is using iron.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 17 Oct 2026 · Folate · neutral · Facebook ↗
      States that folate can affect how the body responds to a supplement.
    • 7 Oct 2026 · Vitamin C · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 14 Aug 2026 · Vitamin C · neutral · Podcast ↗
      Dave Asprey reflects on how new research clarifies the mechanism behind IV vitamin C's anti-cancer effect, vindicating a decades-old idea that was dismissed for the wrong reasons.
    • 5 Aug 2026 · Folate · recommends · Facebook ↗
      Recommends methylfolate as a better option than folic acid.
    • 25 Jul 2026 · Vitamin C · neutral · Facebook ↗
      Notes that plain Vitamin C isn't enough and that most people never think to check for a specific ingredient that makes it work.
    • 16 Jul 2026 · Vitamin C · warns · YouTube ↗
      Dave Asprey recommends taking maybe a gram of vitamin C a day in divided doses, noting that plasma levels peak around 250 milligrams twice a day.
    • 14 Jul 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Qualia Vitamin C Plus, highlighting its combination of seven forms of vitamin C with 250 mg of citrus bioflavonoids, which helps with absorption and use for building collagen and a strong immune system.
    • 9 Jul 2026 · Vitamin C · warns · YouTube ↗
      Warns that taking too much vitamin C can raise oxalate levels, emphasizing that everything has risk and reward.
    • 1 Jul 2026 · Vitamin B12 · recommends · YouTube ↗
      States that Vitamin B12 is extremely important for every kind of brain function and recommends ensuring B12 levels are optimal, around 500, not just barely above normal.
    • 16 Jun 2026 · neutral · Facebook ↗
      Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for iron, which is associated with impaired recovery.
    • 14 Jun 2026 · Vitamin C · recommends · Podcast ↗
      Recommends Vitamin C as the real biological fix for deep focus issues, explaining how the brain hoards it at levels 100 times higher than blood and how to bypass the blood-brain barrier.
    • 11 Jun 2026 · Folate · recommends · YouTube ↗
      Dave Asprey notes that 80% of their clients have a problem absorbing certain forms of folate, and when the exact form of folate or folinic acid is dialed in, clients experience shifts, with the brain waking up as one of the first improvements.
  • Dr. Rhonda Patrick · Iron · uses
    • 4 May 2026 · uses · YouTube ↗
      Recently found out he needed to get on an iron supplement and noticed he gets less sore in his training after taking it.
    • 28 Sep 2026 · Folate · recommends · YouTube ↗
      Recommends ensuring adequate methyl folate intake, ideally through a prenatal vitamin, for women preparing for IVF.
    • 25 Aug 2026 · Vitamin C · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 5 Jun 2026 · Vitamin C · recommends · Instagram ↗
      Recommends nutrients like vitamin C for men to prioritize sperm mitochondrial health.
    • 4 May 2026 · Vitamin C · uses · YouTube ↗
      Dr. Rhonda Patrick's daughter chugs an Emergency fizzy drink in the morning to ensure she gets some vitamin C and micronutrients before school.
    • 5 Feb 2026 · Vitamin C · recommends · Facebook ↗
      Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
    • 22 Jan 2026 · recommends · YouTube ↗
      Advises that menstruating women should ensure they are getting enough iron.
    • 9 Jan 2026 · Vitamin C · neutral · Facebook ↗
      Notes that ~35% of Americans are low in vitamin C.
    • 29 Dec 2025 · Vitamin C · recommends · X ↗
      Recommends increasing vitamin C intake if concerned about skin aging, noting it is an essential cofactor for collagen synthesis.
    • 8 Oct 2025 · Vitamin B12 · warns · Facebook ↗
      Warns that Vitamin B12 enhances light's melatonin-suppressing effects and should be avoided too close to bedtime.
    • 9 Sep 2025 · Vitamin C · warns · YouTube ↗
      Suggests avoiding a multivitamin if it contains biotin before a testosterone blood test to prevent confounding results.
    • 4 Sep 2025 · Vitamin C · neutral · Facebook ↗
      Multiple randomized controlled trials show older adults taking a standard multivitamin (like Centrum Silver) had measurable improvements in processing speed, cognition, and episodic memory.
    • 20 Aug 2025 · Folate · neutral · Instagram ↗
      Notes that dark leafy greens are a great source of folate.
    • 11 Aug 2025 · Vitamin C · uses · X ↗
      Currently takes the Pure Encapsulations O.N.E Multivitamin.
  • Peter Attia · Iron · recommends
    • 8 Jun 2025 · recommends · YouTube ↗
      Recommends iron supplements for women of reproductive age who are iron deficient.
    • 3 Jul 2025 · Vitamin C · stopped · YouTube ↗
      Recommends vitamin C as an important molecule for skin, noting its role as a precursor for collagen synthesis, a powerful antioxidant, and a regulator of complexion for even skin tone.
    • 29 Jun 2025 · Vitamin C · stopped · YouTube ↗
      Tried a vitamin C serum mixed with ferulic acid but stopped using it because she hated the smell. She notes that topical application of vitamin C far exceeds the levels achievable by ingestion for skin benefits.
    • 9 Sep 2024 · neutral · YouTube ↗
      Notes that deficiencies in certain vitamins and minerals, such as iron, can be a cause of hair loss in women.
    • 9 Sep 2024 · Vitamin B12 · neutral · YouTube ↗
      Notes that deficiencies in certain vitamins and minerals, such as B12, can be a cause of hair loss in women.
    • 6 Sep 2024 · Vitamin C · neutral · YouTube ↗
      States that vitamin C deficiency is associated with an elevated risk of cataract, but supplementation to supranormal levels has not been shown to protect against cataract formation.
    • 19 Aug 2024 · Vitamin C · recommends · YouTube ↗
      Mentions the elimination of scurvy through the work of James Lind and the eventual understanding that it was due to vitamin C, initially thought to be just citrus.
    • 19 Aug 2024 · Folate · recommends · YouTube ↗
      Highlights folate supplementation as a significant practical progress in nutrition science, which has radically reduced spinabifida.
    • 8 Apr 2024 · neutral · X ↗
      Delves into the crucial yet often overlooked topic of iron and iron deficiency.
    • 8 Apr 2024 · neutral · YouTube ↗
      Explains that humans consume about 10 to 20 milligrams of iron per day, absorbing roughly 10% of that, which is 1 to 2 milligrams per day, perfectly offsetting the 1 to 2 milligrams lost daily.
    • 8 Apr 2024 · recommends · Podcast ↗
      Peter emphasizes the importance of consuming an adequate amount of iron daily to prevent deficiency.
    • 24 Oct 2023 · Folate · uses · YouTube ↗
      Takes Jarrow methylfolate to keep homocysteine levels below nine, taking the lower of two available strengths once a day.
    • 23 Oct 2023 · Folate · uses · YouTube ↗
      Takes Jarrow methylfolate, a methylated version, once a day at the lower of two strengths, to keep homocysteine levels below nine.
    • 28 Aug 2023 · Folate · neutral · YouTube ↗
      Mentions that in a mouse model for obesity, the amount of folate given to the mother mouse during pregnancy affects the epigenetics of her offspring, leading to changes in coat color and obesity.

RAL Summary

Members OnlyTier 2 for Energy

Tier 2 rests on iron at a full dose, which reduced fatigue in iron-deficient people across several reviews and placebo-controlled trials [1][3], together with 322 reviews that are 88% positive.

Where the evidence disagrees: 54 of the 132 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Blood and circulatory system, Nervous system, Digestive system

Combine with: For its intended purpose of supporting iron levels and energy, Ferrasorb pairs well with vitamin B12 and folate (methylcobalamin and methylfolate) for healthy red blood cell production, and with vitamin A or copper in modest amounts to support iron metabolism. Taking it away from calcium, magnesium, zinc, coffee, tea, and high-fiber foods improves absorption. If iron causes constipation, magnesium glycinate or extra fiber and fluids may help. Only supplement iron if blood tests (ferritin, serum iron, TIBC) confirm a need. For occasional heartburn, look at a separate product such as calcium carbonate or magnesium/aluminum antacids, alginate (sodium alginate), or DGL licorice, and take iron on a different schedule from antacids because they reduce iron absorption.

Possible side effects: The store page's own summary and topic tags mention constipation or stomach issues for some buyers, though none of the readable reviews describes them. The studies given report no side effects.

Supplement Facts

Vitamin C 15 mg · Vitamin B6 5 mg · Folate 667 mcg DFE
Supplement Facts
Serving Size 1 Capsule(s)
Servings Per Container 60
Amount Per Serving% Daily Value
Vitamin C15 mg
Vitamin B65 mg
Folate667 mcg DFE
Vitamin B12300 mcg
Iron36 mg

Other ingredients: Hypromellose, Microcrystalline Cellulose, Leucine, Silicon Dioxide.

Directions: Suggested Use: Take 1 capsule one to three times daily or as recommended by your healthcare practitioner.

Barcode (UPC) 693749750031 · Label source: NIH label database · Report a label change

Show entire label

More energy products

Members OnlyThe highest ranked for the same goal

Read more

Our articles on this subject

Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.