Thorne L-Arginine Review
Thorne L-Arginine - Sustained Release is a single active ingredient supplement presented as a sustained-release capsule. The page headline describes it as a way to maintain healthy blood pressure and support optimal blood flow with sustained-release L-arginine. Product copy states that it supports blood flow to the extremities to benefit heart health, exercise capacity, collagen formation, and sexual wellness. Each serving is 2 capsules, with 60 servings per container, for 120 capsules in total. Each serving provides 1g of L-Arginine. The other ingredients listed are Leucine, Silicon Dioxide, High and Low Viscosity Hydroxypropyl Methylcellulose, Calcium Laurate, and Magnesium (Citrate). The page explains that L-arginine is a conditionally essential amino acid, meaning the body can make it but may need dietary or supplemental intake under certain circumstances or for certain physical conditions. It is described as a building block of protein that helps promote muscle and tissue repair, supports a healthy immune system, and benefits cellular metabolism. A key function noted is its role in producing nitric oxide, which is essential to the regulation of blood flow. The page says that by supporting nitric oxide levels, L-arginine can support cardiovascular health, benefit healthy blood pressure, and optimize blood flow to the extremities. Thorne states that this product combines L-arginine with its Time-Sorb complex to help maintain optimal levels of L-arginine over 24 hours with suggested use. Listed benefits include helping maintain normal blood pressure and vascular elasticity, supporting a healthy heart and vascular system, helping promote cellular repair and collagen formation, supporting blood flow to the extremities to increase work capacity during exercise, and benefiting the occurrence and maintenance of erections during intimacy. Features include a single active ingredient formula for ease of personalized health plans and a sustained release formula to maintain optimal levels over time when used as suggested. Target users include individuals who want to maintain healthy blood pressure, athletes seeking enhanced blood flow during exercise, individuals desiring increased blood flow to the extremities, and individuals who want to support sexual wellness. The Why Thorne section says the formula is clinically studied, tested through multiple rounds of quality control, and trusted by health-care practitioners. The page states the product has been third-party tested and certified to verify label accuracy and to confirm it contains no unsafe levels of contaminants such as heavy metals, pesticides, and microorganisms. The warnings section states the product is contraindicated in individuals with a history of hypersensitivity to any ingredient, and pregnant individuals should consult a health-care practitioner before use. Individuals with a known herpes infection should not take L-arginine without also taking lysine, and L-arginine supplementation is contraindicated in a patient with hepatocellular carcinoma.
We don’t sell supplements. We help you make decisions and get the best price.
Lowest prices
We may earn a commission from some store links. How we choose.
Finding the lowest prices at the stores now. This takes a few seconds.
Study, Trial or Testing Result Summary
Members Only32 human studies · 14 improved
12 of these 32 human studies gave l-arginine by drip or injection, not by mouth.
The research on L-arginine for blood flow is mixed. Of 32 human studies, 14 found an improvement and 12 found no effect. The largest and longest trial gave 133 people with leg artery disease 3 grams a day for 6 months, close to what this product gives at three capsules a day. Blood vessel widening did not improve, and walking distance improved less than with placebo, 11.5 percent versus 28.3 percent [1]. Most positive results used much higher doses or short studies. A single 6 gram dose improved arm artery widening in 35 people with high blood pressure [2]. In 12 adults over 70, 8 grams twice a day for two weeks improved artery widening [3]. A 30 gram infusion into the vein raised brain artery blood flow speed by about 28 percent in 55 people [4], but this is not comparable to a capsule. Other trials found no benefit, including a single 3 gram dose in 30 healthy young adults [5]. In 19 older adults with diabetes or high blood pressure, 4 days of L-arginine made small blood vessel function in the fingers worse [6]. Animal and cell studies are never counted.
See all 32 studies →Hide the studies
- A review of 27 studies in people with migraine with aura found no clear blood vessel lining problem; one study showed lower brain artery response to L-arginine in migraine patients.Endothelial function in migraine with aura - a systematic review.
- A review of 25 studies in pregnant women (plus animal studies) found L-arginine lowered blood pressure, reduced pre-eclampsia, and improved blood flow between placenta and fetus in growth-restricted pregnancies compared with controls.L-Arginine supplementation in pregnancy: a systematic review of maternal and fetal outcomes.
- A review of 19 trials in heart failure found that supplements including L-arginine improved the heart's pumping ability (ejection fraction), but no blood flow result for L-arginine alone was given.Dietary strategies and nutritional supplements in the management of heart failure: a systematic review.
- In 133 people with leg artery disease, 3 g of L-arginine daily for 6 months did not improve blood vessel widening and walking distance improved less than with placebo (11.5% versus 28.3%).L-arginine supplementation in peripheral arterial disease: no benefit and possible harm.
- In 35 people with high blood pressure, a single 6 g dose of L-arginine improved artery widening in the arm (from 1.7% to 5.9%) 1.5 hours later, while placebo did not.Oral L-arginine improves endothelial dysfunction in patients with essential hypertension.
- In 30 healthy young adults, a single 3 g dose of L-arginine did not enhance artery widening or exercise performance compared with placebo around resistance exercise.Endothelial, Cardiovascular, and Performance Responses to L-Arginine Intake and Resistance Exercise.
- In 24 healthy young adults, a single dose of Nitrosigine (1.5 g) or citrulline malate (8 g) raised blood vessel dilation by 31% and 34% an hour later, compared with a 2% drop on placebo.Acute effects of Nitrosigine® and citrulline malate on vasodilation in young adults.
- In 10 people with type 1 diabetes and 10 healthy people, an L-arginine infusion increased pulsing blood flow in the back of the eye and lowered blood pressure similarly in both groups.Nitric oxide and ocular blood flow in patients with IDDM.
- In 19 older adults with diabetes or high blood pressure, 4 days of L-arginine worsened small blood vessel function in the fingers compared with placebo and did not help thinking skills.Arginine impairs endothelial and executive function in older subjects with cardiovascular risk.
- In 18 critically ill people with septic shock, 72 hours of intravenous L-arginine did not improve small blood vessel blood flow or organ function compared with an alanine control, despite raising nitric oxide production.A randomized-controlled trial of arginine infusion in severe sepsis on microcirculation and metabolism.
- In 18 abdominally obese men, adding 0.8 to 3.0 g of L-arginine to beetroot powder did not improve blood vessel flow-mediated dilation after a high-fat meal compared with meals without it.Effects of Beetroot Powder with or without L-Arginine on Postprandial Vascular Endothelial Function: Results of a Random…
- In healthy adults given intravenous L-arginine, the kidney blood flow drop caused by angiotensin II was not reduced compared with placebo, although L-arginine alone raised kidney blood flow.Exogenous L-arginine does not affect angiotensin II-induced renal vasoconstriction in man.
- In 15 men, a single 6 g dose of L-arginine increased blood volume in the arm muscles during recovery from exercise but did not improve strength compared with placebo.Acute l-arginine supplementation increases muscle blood volume but not strength performance.
- In 12 healthy adults over 70, 8 g of L-arginine twice daily for 14 days improved brachial artery widening compared with placebo.Oral L-arginine improves endothelial function in healthy individuals older than 70 years.
- In 12 healthy lean adults during an insulin clamp, an infusion of L-arginine raised blood flow and glucose uptake compared with saline, while D-arginine had no effect.L-arginine but not D-arginine stimulates insulin-mediated glucose uptake.
- In 8 healthy young men, a single 10 gram arginine drink taken with resistance exercise did not increase thigh muscle blood flow or muscle protein synthesis compared with a control drink.Bolus arginine supplementation affects neither muscle blood flow nor muscle protein synthesis in young men at rest or af…
- In 8 healthy men, a single 30 gram intravenous L-arginine dose lowered blood pressure and resistance in the blood vessels, while a single 6 gram dose given by vein or by mouth did not significantly change blood pressure.L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship.
- A single 10 g oral dose of L-arginine taken with carbohydrate did not change blood glucose, insulin, forearm blood flow or blood pressure in healthy males, whether rested or after exercise.L-arginine ingestion after rest and exercise: effects on glucose disposal.
- In people with heart failure from blocked arteries, infusions of L-arginine and vitamin C were studied for effects on nerve control of blood vessels, and healthy people showed a clear ability to adjust vessel resistance that the heart failure patients lacked.Influence of L-arginine and vitamin C on the autonomic nervous system in chronic heart failure secondary to ischemic car…
- In young heart transplant recipients with high blood pressure, oral L-arginine was reported to reverse blood vessel inner lining dysfunction and lower high blood pressure.Effect of oral L-arginine on oxidant stress, endothelial dysfunction, and systemic arterial pressure in young cardiac tr…
- In a double-blind crossover trial in people with primary Raynaud's phenomenon, 8 grams of L-arginine daily for 28 days did not change finger blood vessel dilation compared with placebo.Oral L-arginine supplementation and cutaneous vascular responses in patients with primary Raynaud's phenomenon.
- In 55 people with heart disease risk factors, a 30 g L-arginine infusion raised brain artery blood flow speed by about 28%, with a greater response in those with prior stroke or mini-stroke (29%) than those without (21%).L-arginine-mediated vasoreactivity in patients with a risk of stroke.
- In 25 people with a hereditary small vessel disease and 24 controls, an L-arginine challenge caused a larger blood vessel widening response in the patients, which suggests impaired vessel lining function rather than a benefit.Enhanced L-arginine-induced vasoreactivity suggests endothelial dysfunction in CADASIL.
- In 13 people with familial high cholesterol and 13 controls, the study found tetrahydrobiopterin restored blood vessel function in the forearm; the abstract does not report a benefit from L-arginine alone.Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
- In 14 people with high cholesterol and 11 with normal cholesterol, a single L-arginine infusion improved blood flow response in the forearm of the high-cholesterol group but not in the normal group.L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans.
- Arginine delivered through the skin did not change blood vessel widening in young Black or white women, so it did not explain the reduced skin blood vessel function seen in Black women.Contributions of endothelin-1 and l-arginine to blunted cutaneous microvascular function in young, black women.
- In 8 people with chest pain and normal coronary arteries, an infusion of arginine directly into the heart's artery increased blood flow in response to acetylcholine, while it had no effect in 8 control participants.Effects of L-arginine supplementation on endothelium-dependent coronary vasodilation in patients with angina pectoris an…
- In patients with a rare inherited mitochondrial disease (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes), two years of oral L-arginine brought blood vessel function, measured by flow-mediated dilation, back up to the level of controls.Endothelial dysfunction in MELAS improved by l-arginine supplementation.
- In 11 children, an arginine infusion lowered blood pressure, and the drop was linked to higher levels of citrulline, consistent with more nitric oxide being made.L-arginine infusion lowers blood pressure in children.
- A single 0.9 gram dose of arginine improved blood vessel dilation in young, trained healthy men, but did not change it in older or less active men.L-arginine as dietary supplement for improving microvascular function.
- In people with a rare inherited mitochondrial disease, two years of oral arginine supplementation restored blood vessel function to control levels and reduced the frequency and severity of stroke-like episodes.MELAS and L-arginine therapy.
- In people with familial amyloid nerve disease, arginine given into the arm's artery caused blood vessels to widen as it did in control participants, although their nitric oxide production was lower and their blood flow was reduced at rest.Role of nitric oxide in the peripheral vessels of patients with familial amyloidotic polyneuropathy (FAP) type I.
Review Totals and Summary
Members Only1,972 reviews · 92% positive
**Overall:** Thorne L-Arginine capsules are rated very positively across the two stores, which carry about 815 ratings in total. The written feedback is short and mostly general, so it says more about perceived benefit and brand trust than about detailed results. **What buyers say it did for them:** Several reviewers report a noticeable effect. One says they "Definitely feel better and a difference." Another reports that "my menstrual cramps have become much less severe." Others use it for exercise and circulation, such as a buyer who takes it before workouts "to support circulation, exercise performance, and overall cardiovascular health." One buyer was recommended it by a doctor for a frozen embryo transfer and called it "good," without giving results. **What buyers complain about:** There are very few complaints. The one mixed note comes from a buyer who bought it "for extending workout sessions," reported "No side effects," and was "looking for more effects." They had not yet seen the stronger results they hoped for. One store's histogram shows a single 1-star rating with no written text, so the reason is unknown. The other store's histogram shows one 2-star and one 3-star rating, also with no explanation in the visible reviews. Nothing written criticizes taste, size, or packaging. **Taste, smell, pill size or form:** The reviews do not discuss taste, smell, or capsule size. One store summary notes that the written feedback contains no complaints about these. A review that quotes the product description calls it a sustained-release formula. Reviews of other forms of this product were left out. **Value for money:** Buyers who mention price accept it. One says "I believe it's worth the price" after a doctor recommended the brand. Another says the brand is "very high quality and the price reflects that." Both treat the cost as a fair trade for quality rather than a bargain. Reviewers also praise the brand's reliability, with one saying the "reputation is precise with quality." One buyer also praised the "good time delivery." **Who it seems to suit and who it did not:** The product seems to suit people who follow a doctor's or nutritionist's suggestion and want support for circulation, heart health, or workouts. It also suits those who trust the brand's quality and accept a higher price for it. Buyers also mention it for menstrual cramps and fertility treatment, but these come from single reviews. It may suit less well anyone who expects a strong or quick performance boost, given the buyer still waiting for more effects. The written evidence is thin: there are only a handful of short reviews against hundreds of ratings, and the long-term or dosing experience is not covered.
Biohacker Summary
Members Only10 of 10 recommend it
Arginine is the main ingredient here, and the panel leans toward recommending it, though several members stay neutral and a few have stopped. Most of the ten take or suggest it to raise nitric oxide and blood flow, mainly before workouts, and some also link it to growth hormone, sexual performance, or calmness when paired with foods rich in a calming brain chemical. Forms mentioned include plain L-arginine, arginine nitrate, and arginine ketoglutarate, and the only dose given was about 5 grams for sexual performance; several also pair it with citrulline, ornithine, or proline. Cautions came up often: two warned it can trigger cold sore outbreaks, two said taking it too close to exercise can work against growth hormone, and one said it has fallen out of favor because of absorption problems, with citrulline now preferred. Two panelists stopped taking it, one because he saw no real change in blood flow and one who switched to a different compound after a gene finding and noticed a better workout pump.
See all 9 biohackers →Hide the biohackers
Ben Greenfield · Arginine · neutral
- Mentions an arginine link to thymus metabolism, noting that immune cells require a lot of arginine.
- Recommends chia and flax seeds as they are rich in arginine, which can help supply nutrients that patients may be lacking.
- Recommends L-arginine, around 5 grams, as an aid for sexual performance and to combat erectile dysfunction.
- Mentions arginine as a supplement that can increase blood flow for pre-workout.
- Ben likes it when he takes a pre-workout like arginine and gets a wonderful rush in energy and blood flow.
- Ben says his secret weapon for withstanding the cold is a higher dose niacin or niacinamide, combined with a blood flow precursor like arginine or citrulline, and T2 thyroid hormone.
- Recommends L-arginine as an amino acid that synthesizes nitric oxide.
- Warns that taking arginine prior to red light therapy can aggravate the formation of excess reactive oxygen species.
- Recommends arginine to enhance the effects of Hyperbaric and PEMF by increasing blood flow.
- Has used Joymode, a sexual performance booster with Arginine, Citrulline, and Vitamin C, and finds that it works pretty well, though it is a central nervous system stimulant.
Siim Land · Arginine · neutral
- Explains that blood vessels normally make nitric oxide from the amino acid L-arginine through an enzyme called eNOS.
- Notes that arginine is good for increasing nitric oxide and is found in many pre-workout supplements, but there are conflicting thoughts on its effectiveness.
- Tells older people to take Arginine Ketoglutarate because the arginine is helpful as a low-key vasodilator.
- Recommends Arginine before workouts to promote blood flow, which leads to better workouts and physical performance.
- Used to take Arginine but switched to Agmatine sulfate after discovering a mutation in his NOS3 gene, which synthesizes nitric oxide, and noticed massive differences in his 'pump' during workouts.
- Warns that Arginine can have negative adverse reactions with meds like a med, advising caution and checking product packaging for interactions.
- Suggests swapping out calcium Alpha-ketoglutarate for Arginine Alpha-ketoglutarate, especially if not on a low calcium diet, as it does not contain calcium.
- Suggests taking a little extra arginine when fighting an infection, as it is used a lot by the body during an infection and can help convert to citrulline.
- Increased his intake of arginine because his levels were low, and they went up.
- Is putting arginine in their meteorite scrub.
Dr. Eric Berg · Arginine · recommends
- Recommends consuming arginine, along with proline and ornithine, in the meal that breaks a prolonged fast to get the benefits of stimulating stem cells.
- Recommends arginine as a potent way to increase growth hormone, but warns against taking it too close to a workout as it will lower growth hormone.
- Explains that herpes and shingles viruses need the amino acid arginine to survive.
- Recommends L-arginine to increase nitric oxide to help prevent heart attack.
- Mentions that Arginine can trigger nitric oxide.
- Recommends taking 3 to 6 grams of Arginine daily on an empty stomach 30 minutes before a workout, as it increases growth hormone by inhibiting somatostatin.
- Recommends L-arginine as one of the best natural remedies for hypertension because it supports the production of nitric oxide.
- Mentions L-Arginine as a natural form that increases nitric oxide, which can help with erectile dysfunction.
- Recommends L-Arginine as a solution with minimal side effects to help make more nitric oxide and manage high blood pressure, suggesting taking half a scoop or a whole scoop each day in powder form.
- Mentions that some people use L-arginine, an amino acid, and notes that some studies show it works for erectile dysfunction.
Dave Asprey · Arginine · recommends
- Dave Asprey recommends Joy Mode, an electrolyte packet for sexual performance, to be taken one packet about 45 minutes before sex, as it contains clinical doses of L-citrulline, arginine nitrate, ginseng, and vitamin C to increase nitric oxide levels.
- Has tried arginine over the years but did not notice a significant difference in blood flow.
- Recommends L-arginine, or anything that leads to vasodilation, to boost the power of EWOT when taken beforehand.
- Has added Arginine to his Wonderfeel product as a powerful antioxidant to reduce DNA damage, which in turn reduces the need for PARP to consume NAD, and considers it a foundational longevity molecule.
- Notes that companies are now creating pre- and post-op surgical supplementation with arginine, similar to what he had figured out years ago.
- Dave Asprey says that the case for arginine isn't very strong and that taking high-dose Arginine can actually divert metabolism away from nitric oxide production and make things worse if you have endothelial dysfunction.
- Discusses a new study showing arginine supplementation causing more harm than good, and suggests evaluating supplements based on multiple pillars of evidence, such as lifespan extension in animals and epidemiological data in humans.
- Personally takes L-arginine, an amino acid, to increase vasodilation and nitric oxide levels, noting that it is a useful, well-studied supplement.
- Recommends taking supplements like L-arginine to help synthesize nitric oxide.
- Warns that taking excess L-arginine or L-citrulline would likely have a limited impact on N.O. production and that high-dose L-arginine may pose potential health risks.
Dr. Rhonda Patrick · Arginine · recommends
- Recommends arginine as a blood flow enhancer that boosts nitric oxide, opens up blood vessels, and can improve how one feels during endurance or high-rep sessions, also sharpening mental clarity.
- Notes that arginine has fallen out of favor as a performance enhancer due to bioavailability issues and concerns about cold sores, with citrulline now being the preferred approach.
- Discusses whether nitric oxide boosters like beetroot, citrulline, and arginine work.
- The naturally occurring amino acid arginine makes cavity-prone dental plaque less acidic after sugar intake, potentially making plaque less damaging during periods of sugar exposure.
Andrew Huberman · Arginine · neutral
- Mentions Arginine in the context of growth hormone supplements.
- Huberman mentions arginine as a nonprescription substance that increases blood flow.
- Recommends Arginine for growth hormone.
- Notes that arginine can improve performance for long bouts of exercise due to vasodilation, but warns that it can increase the likelihood of herpes cold sore outbreaks.
- Discusses supplements that increase growth hormone, such as Arginine and Ornithine, but warns that Arginine and exercise together can be counter-productive.
- Mentions that a few studies suggest arginine, an amino acid, might increase slow wave sleep, but advises caution as it can have other effects, including on the heart.
- Notes a caution about Arginine and Citrulline in relation to cold sores.
- Huberman mentions that some studies suggest arginine could increase slow-wave sleep, but advises checking for its effects on the heart and other systems.
- Discusses that arginine can substantially increase growth hormone levels, with doses ranging from 3 to 10 grams, but notes that more than 9 grams can blunt the effect and cause GI disturbance.
- Huberman mentions that some people like beet juice and related compounds that increase arginine and vasodilation.
Thomas DeLauer · Arginine · recommends
- Recommends Arginine Nitrate and other arginines to improve tissue quality and enhance power output during workouts.
- Recommends Arginine Nitrate for enhancing tissue quality and muscle performance.
- Recommends taking L-Arginine, possibly with GABA-influencing foods, as it can increase blood flow to the brain and significantly boost GABA levels in the brain, which helps with calmness.
- Recommends adding L-Arginine, a dirt cheap supplement, along with Gaba-rich foods, to increase Gaba's availability to cross the blood-brain barrier, especially the day after drinking.
- Notes that Sacha Inchi protein is high in Arginine, which is being investigated for its influence on obesity, mitochondrial biogenesis, brown adipose tissue, and fatty acid oxidation genes.
- Recommends arginine to combat erectile dysfunction and improve sexual desire, citing a meta-analysis that found 1.5 to 5 grams was effective.
- Recommends getting arginine in the diet, as it is a strong activator of mtor, which is desired for building muscle and creating big spikes in mtor for short amounts of time.
- Warns that arginine cannot be effectively used in supplement form because it is heavily broken down and catabolized by the gut microbiome, making it not bioavailable for improving blood flow.
- Suggests adding arginine or citrulline malate on longer or higher intensity workout days to increase nitric oxide, which allows for more blood flow to the gut, improving oxygen and nutrient delivery.
- Recommends getting extra arginine, as it is a strong activator of mtor, which is desired for building muscle.
Dr. Mark Hyman · Arginine · neutral
- Notes that arginine is important for nitric oxide production, which dilates blood vessels and helps with inflammation.
- Mentions arginine as one of the things that can be used to repair mucosal membranes as part of the 'repair' step in the 4R program.
- Recommends certain supplements like Arginine to naturally help build growth hormone.
- Explains that Arginine is an amino acid that is a precursor for nitric oxide, which causes vasodilation and can help lower blood pressure.
- Raises the question of whether taking arginine, which increases nitric oxide in the body, could be beneficial.
- Notes that foods containing arginine, like nuts, can activate the herpes virus.
- Discusses whether people should be taking arginine to increase nitric oxide in the body, noting that there are dietary supplements that introduce arginine precursors and L-arginine.
- Recommends arginine, an amino acid that arteries use to make nitric oxide, which dilates blood vessels, and suggests supplementing with it for symptomatic Raynaud's.
- Explains that arginine is the amino acid precursor to nitric oxide and that taking more arginine will lead to more nitric oxide production. He personally takes a powder containing 5 grams of arginine every single morning.
- Recommends consuming arginine, an amino acid and precursor to nitric oxide, noting that taking in more arginine will lead to more nitric oxide production, as shown in various studies.
Peter Attia · Arginine · neutral
- Notes that nitrogen from arginine goes to nitric oxide, which is involved in vasodilation.
- Notes that the Tor pathway evolved to detect both leucine and arginine, at least in most tissues, but the reason for sensing these two structurally different amino acids is a mystery.
RAL Summary
Members OnlyTier 4 for Circulation
The studies on L-arginine for blood flow disagree, and the largest and longest trial at a dose near this product's found no benefit, so they do not show a clear improvement for tier 2. So it is graded Tier 4, lower than the rules alone gave.
Take 3 servings a day (6 capsules) to match the dose that worked in the studies.
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 12 of the 32 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Cardiovascular system
Combine with: For blood flow and nitric oxide support, pair L-Arginine with L-Citrulline, which raises arginine levels more effectively and sustainably, and with beet root or other nitrate sources. Pycnogenol (French maritime pine bark) has clinical data showing synergy with arginine for erectile function. Vitamin C and other antioxidants help preserve nitric oxide bioavailability, and magnesium supports healthy vascular tone. If the user is specifically after libido, consider adding ashwagandha, tongkat ali, fenugreek, maca or zinc to address hormone and desire pathways. Avoid combining with prescription nitrates or PDE5 inhibitors without a physician's guidance, because of additive blood pressure lowering, and use caution with meds.
Possible side effects: One small trial found 4 days of L-arginine worsened small blood vessel function in the fingers of older adults with diabetes or high blood pressure. A reviewer reported no side effects.
Supplement Facts
L-Arginine 1 g
| L-Arginine | 1 g | † |
Other ingredients: Hydroxypropyl Methylcellulose, Calcium Laurate, Magnesium Citrate, Hypromellose, Leucine, Silicon Dioxide.
Directions: Suggested use: Take 2 capsules two times daily or as recommended by your health-care practitioner.
Barcode (UPC) 693749525028 · Label source: NIH label database · Report a label change
Show entire label
More circulation products
Members OnlyThe highest ranked for the same goal
Read more
Our articles on this subject
- How to Lower Diastolic Blood Pressure for LongevityArticle · Sep 17, 2026
- Supplements for Focus and Mental ClarityArticle · Jun 16, 2026
Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
Privacy policyConsumer health dataAffiliate disclosureTermsDo Not Sell or Share My Personal InformationCookie settings