Thorne Super EPA Pro Review
Super EPA Pro is a Thorne omega-3 supplement that provides a high concentration of EPA, an omega-3 fatty acid shown to enhance the metabolism of blood fats, including triglycerides. The page describes it as supporting cardiovascular health with a higher level of EPA than standard omega-3 products. Each two-softgel serving provides 1,300 mg EPA and 320 mg DHA. The product is listed as 120 gelcaps per container, with a serving size of 2 gelcaps and 60 servings per container. The Summary section says to take 2 gelcaps two times daily. The product is described as delivering a high concentration of the omega-3 fatty acid EPA to support cardiovascular health, help maintain already normal triglyceride and cholesterol levels, promote healthy circulation, and enhance mood and cognitive function. It also says the product supports a healthy inflammatory response throughout the body and contributes to overall whole-body wellness. The page notes that the gelcaps are easy to swallow and smaller than many competitors. It states that the product uses CO2 extraction for purity and is produced with sustainable fish harvesting practices. The product details list the benefits as helping maintain already normal triglyceride and cholesterol levels, supporting healthy circulation by promoting blood vessel elasticity and blood flow, enhancing mood and supporting cognitive health, and promoting a healthy inflammatory response. The features section repeats the EPA and DHA amounts, states that CO2 extraction uses no solvents for a clean product free from heavy metals, and notes that sustainable fish harvesting practices ensure a stable supply. The page says Thorne formulates the product with the scientific rigor the brand is known for, with each ingredient carefully selected, clinically studied, and tested through multiple rounds of quality control. It says the product has been third-party tested and certified to verify that what is in the package matches the label and that it contains no unsafe levels of contaminants such as heavy metals, pesticides, and microorganisms. The comparison table places Super EPA Pro beside Omega-3 with CoQ10 and Super EPA NSF Certified for Sport. Super EPA Pro is the EPA-forward option in that group, with 1,300 mg EPA and 320 mg DHA per serving and no additional active ingredients. The warnings section says the product is contraindicated for people with a history of hypersensitivity to its ingredients. It notes that the omega-3 fatty acids are derived from fish. It advises pregnant users to consult a health-care practitioner before use. The page reports no known adverse reactions or contraindications at publication date.
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Study, Trial or Testing Result Summary
Members OnlyHuman studies
No ingredient studies were provided for this product and this goal, so we cannot say from research whether it helps heart health or blood flow. The store listing says each two-gelcap serving gives 1300 milligrams of eicosapentaenoic acid and 320 milligrams of docosahexaenoic acid, the two main omega-3 fats in fish oil. However, the label we hold shows only purified water, so we could not check these amounts against the label itself. Because no human studies on blood flow for these ingredients were given to us, there is no study result to report on whether this dose works, what it changes in the body, or how it compares with other fish oils. Buyers rate the product highly, with most ratings at four or five stars, but ratings show satisfaction, not proof that it improves blood flow. Until studies on these ingredients for heart blood flow are added, members should treat any heart benefit from this product as unproven by the evidence in this record. Animal and cell studies are never counted.
Review Totals and Summary
Members Only561 reviews · 92% positive
Buyers are mostly positive about Thorne Super EPA Pro softgels, praising the brand, the quality and the lack of fishy taste, though many say it is too early to judge results and a few find it expensive. Across the stores it carries about 561 ratings, weighted heavily toward four and five stars. This summary covers the softgels only; reviews of other forms were left out. **What buyers say it did for them:** Most feedback is early and tentative. One buyer reports "Increase in alertness and stamina," and another taking it for triglycerides says "I seem to notice some." A store summary mentions one reviewer who says it helps with inflammation after heavy training. Others are still waiting. One says "Just started it need time," and one says "I like it so far." A Vitacost reviewer, after about a month, was not sure they felt a huge difference but planned to keep taking it. Several reviews say the buyer is still waiting to see whether it works, so firm evidence of benefit is thin. **What buyers complain about:** Complaints are few and mostly not about the product itself. Price is the main reservation, and one reviewer calls it very expensive. Another says they are unsure of a big difference after a month. One reviewer notes a bit of an after-fish taste. Some low or off-topic comments concern the store's surveys rather than the softgels, and they say nothing about how the product performs. The Thorne.com page's AI summary says opinions on taste vary. **Taste, smell and form:** This is a strength for most buyers. One says "No aftertaste," another "There is no taste or reflux experience which is a positive." Store summaries say the gelcaps are easy to swallow, with no unpleasant fishy aftertaste, and one reviewer says they taste like nothing. The one dissent is the buyer who notes a slight fish aftertaste. Reviews give no detail on pill size beyond ease of swallowing. **Value for money:** Buyers accept the cost as the price of quality. One says "Yes it's pricey, but well worth the investment for your health." Another reviewer on Vitacost calls it very expensive without saying whether it was worth it. No one calls it a bargain. **Who it seems to suit:** The product appeals to people who research brands and trust Thorne. One says "Thorne consistently has high-grade, high-efficacy products," another "After researching different brands... This was the best one I found!" One buyer chose it because a doctor recommended a higher-dose omega-3 for triglycerides, and another cites a high rating from an independent lab-testing group. Buyers also like its EPA focus, with one store summary describing it as one of the only quality EPA-biased omega-3 supplements. Those who dislike fishy aftertaste may also like it. People looking for a cheap fish oil, or wanting proof of results right away, are less well served, since price is the main complaint and most results reports are still early. The reviews give no detailed evidence about the cardiovascular or triglyceride claims beyond what buyers hope for.
Biohacker Summary
Members Only7 of 10 recommend it
Omega-3 fatty acids are listed as a smaller ingredient in this product, yet all ten panelists spoke about them, and six of the ten lean toward recommending them while four stay neutral. People take them for heart health and lower triglycerides, brain function, calming inflammation, fertility, skin, and slowing biological aging. Forms vary: several favor oily fish like salmon and sardines or fish oil, and one suggests taking them with a fat-containing meal to absorb more. Doses mentioned run from 1 gram a day up to 2 to 4 grams a day of combined EPA and DHA, and one warned that most people underdose because standard capsules hold little EPA and DHA. As a caution, one panelist said the research on omega-3s is not strong for preventing hard heart disease outcomes, and none of them said they stopped taking them.
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Dr. Eric Berg · Omega-3 Fatty Acids · recommends
- Recommends wild-caught salmon as a healthy food to eat every day, noting it contains about 2000 mg of omega-3s in just 3 ounces.
- Recommends wild salmon as it is rich in omega-3 fatty acids, which help reduce inflammation and support brain health and cognitive function, especially important as one ages.
- Recommends DHA, an omega-3 fatty acid, as a natural remedy that, along with sweet wormwood, can trigger iron into an explosion to hit cancer.
- Dr. Eric Berg mentions that sardines are packed with omega-3 fatty acids, which support brain health and metabolism.
- Mentions that wild salmon, specifically half a fillet, has 970 mg of potassium, zero carbohydrates, a good amount of magnesium, and is loaded with omega-3 fatty acids.
- Discusses what would happen if one consumed omega-3 fatty acids every day for 30 days, highlighting their benefits for brain health, heart health, and various conditions like dry eyes, dermatitis, and high blood pressure, as well as supporting calcium absorption and promoting better sleep.
- Recommends getting plenty of omega-3 fatty acids to support joint and metabolic health.
- Recommends consuming foods rich in vitamin D, including fatty fish, to boost vitamin D levels.
- Recommends fatty fish as the best type of protein for inflammation.
- Recommends fatty fish, including salmon, mackerel, and sardines, as dietary sources of vitamin D.
Siim Land · Omega-3 Fatty Acids · recommends
- Recommends taking omega-3s, including EPA and DHA, with a fat-containing meal to increase absorption.
- Increased his omega-3 intake to achieve a higher omega-3 index, which is associated with greater insulin sensitivity and better metabolic health markers.
- Increased his omega-3 index to 9.5% and notes that omega-3s have strong evidence for reducing elevated triglycerides.
- Mentions that EPA and DHA Omega-3s support heart and brain function and can lower triglycerides, with a higher omega-3 index associated with lower heart disease, Alzheimer's and mortality risk.
- Recommends Omega-3s for triglycerides and cardiovascular health, based primarily on human research, especially randomized controlled trials showing measurable benefits.
- Recommends choosing an omega-3 supplement from a brand that uses independent third-party testing and publishes a recent certificate of analysis, verifying EPA and DHA amounts, and testing for heavy metals, contaminants, and oxidation markers.
- Lists Omega-3s as one of 15 supplements backed by human studies.
- Explains that omega-3s can alter mitochondrial membranes and have broader cardiometabolic effects, making mitochondria more responsive to cellular signaling and oxidative stress from exercise, but they don't increase maximal mitochondrial respiration.
- Notes that 75% of people aren't meeting the daily recommendation for omega-3s and that Japanese people eat 2-3x more omega-3s per day than Americans or Europeans, which reflects in their higher omega-3 index.
- Thinks omega-3s have some of the strongest evidence and are worth considering.
Andrew Huberman · Omega-3 Fatty Acids · recommends
- AG1 is giving away a free bottle of omega-3 coenzyme Q10 with your first subscription.
- Mentions that AG1 is giving away a free bottle of Omega-3 co-enzyme Q10 with the first subscription to AG1 Pro.
- Discusses Omega-3 Fatty Acids and EPA.
- Mentions that AG1 is offering a free bottle of Omega-3 co-enzyme Q10 with a first subscription to AG1 Pro.
- Recommends a free bottle of Omega-3 co-enzyme Q10 with the first AG1 Pro subscription.
- Mentions Omega-3s in the context of the microbiome and processed foods.
- Recommends Omega-3 co-enzyme Q10, which is offered as a free bottle with the first AG1 Pro subscription.
- States that getting 1 to 3 grams of EPA essential fatty acid per day can improve mood and cognitive function, supporting focus and concentration.
- Discusses Omega-3 Fatty Acids.
- Discusses omega-3s, artificial sweeteners, fructose, and fats.
Thomas DeLauer · Omega-3 Fatty Acids · recommends
- Recommends fish oil supplements as an omega-3 source for gut health, as they help reduce inflammatory signaling while tissue repairs.
- Recommends high-dose omega-3s, specifically 2 to four grams of combined EPA and DHA daily, to lower hepatic fat output and improve chylomicron clearance, which helps with non-fasting triglycerides.
- Recommends omega-3s, specifically 4 grams a day, to boost the muscle building response by making muscle cell membranes work better for the mTor switch to fire, and specifically mentions Pury for their clean, third-party tested omega-3s.
- Recommends consuming more omega-3s to help balance the mitochondrial membrane, as it will absorb more omega-3s instead of omega-6s.
- Recommends consuming more omega-3s to drive down inflammation.
- Recommends omega-3s, stating that a meta-analysis found 1,000 mg significantly reduced liver fat by shutting down inflammatory signals that promote fat storage, and advises looking for a triglycerol form for better absorption and to avoid oxidation.
- Recommends fatty fish like salmon and sardines, aiming for two to three servings per week, especially around a workout, because their omega-3s, particularly DHA, increase BDNF expression.
- Considers omega-3s a fundamental for brain protection, recommending both dietary sources and supplementation for EPA and DHA, as they produce pro-resolving mediators to limit inflammation.
- Recommends timing omega-3 intake around workouts because they directly help build and keep muscle by making muscle more responsive to growth signals and fighting anabolic resistance as one ages.
- Notes that Scandinavians consume fatty fish multiple times a week as part of their diet, contributing to their long lifespan and healthspan.
Dave Asprey · Omega-3 Fatty Acids · recommends
- Suggests that omega-3s may help slow aging and support cellular repair.
- Recommends omega-3s, noting that 1 gram a day slowed epigenetic aging by up to 4 months in a randomized trial of people over 70.
- Dave Asprey recommends Omega-3, citing a randomized trial showing 1g a day slowed epigenetic aging in older adults, but warns that most people underdose due to low EPA and DHA content in standard capsules.
- A review of 41 human studies testing interventions against newer-generation epigenetic clocks found favorable changes for exercise, caloric restriction, omega-3s, plant-rich diets, multivitamins, a med, pitavastatin, and ketamine.
- Recommends getting nutrients like omega-3s from real food or Vision 101 for eyesight.
- Recommends adding omega-3 fats to improve how neurons absorb and use nutrients like vitamin C.
- States that Fatty15 supports cells better than omega-3s or fish oil, but he uses both.
- Notes that Inuit people consumed very high levels of omega-3s, specifically EPA and DHA, which contributed to their health on a whale blubber diet.
- Lists Omega-3s as a nutrient that forms the structure and different parts of the brain.
- Uses both C15 and omega-3s, noting that C15 supports cells better than omega-3s or fish oil with three times more benefits.
Dr. Rhonda Patrick · Omega-3 Fatty Acids · neutral
- Mentions that EPA is an omega-3 examined in mortality analysis and found primarily in seafood.
- States that Omega-3 fatty acids are very important for sperm health.
- Omega-3s may help slow biological aging, with added benefits when combined with vitamin D and strength training. In a 3-year randomized trial of healthy, mostly active older adults, omega-3 alone slowed several DNA-based aging clocks.
- Recommends regular intake of omega-3 rich seafood and supplementation with omega-3 fatty acids if it's appropriate for one's lifestyle, as they are beneficial for the heart by resolving inflammation and preserving membrane fluidity.
- Notes that a 100 mg per day increase in omega-3 fatty acids was associated with lowering the risk of Alzheimer's disease and cognitive decline by 10%, and that it takes about two grams a day to get to a high omega-3 index if one has a low index.
- Practical habits to help keep chronic inflammation in check include getting enough omega-3s.
- States that Omega-3s, specifically EPA and DHA, may be the most potent naturally occurring dietary compounds for reducing inflammation, and that about 2 g/day of combined EPA and DHA can raise a low omega-3 index.
- Recommends fatty fish as a source of healthy fats for muscle gain.
- Mentions that an omega-3 supplement might not be working, and one would not know without taking the Omega-3 index test.
- Recommends considering omega-3s to improve mood.
Dr. Mark Hyman · Omega-3 Fatty Acids · neutral
- Mentions omega-3 fats as existing biomarkers that play a role in mental health, which Function Health includes in their measurements.
- Mentions that omega-3s are anti-inflammatory and helpful.
- Tries to supplement with omega-3s for psoriasis and considers them the one clearly clinically effective skin nutrient for skin, hair, and nails.
- Emphasizes the importance of focusing on omega-3s, noting that a national crisis of omega-3 deficiency exists and that low omega-3 levels are a significant problem, more so than omega-6s.
- Consumes omega-3 fats through salmon at dinner.
- Notes that omega-3s are important nutrients for brain performance and aging, and that many people have gaps in these nutrients.
- Recommends omega-3 fats from wild fish, seafood, and certain nuts and seeds to fight inflammation.
- Mentions omega-3 fats as something that might be helpful for gut repair.
- Used omega-3 fats as part of a protocol to rebuild the gut microbiome and heal the gut of a nine-year-old girl with severe behavioral issues.
- States that omega-3 fats from fatty fish, flax, and walnuts help balance inflammatory pathways, but no supplement can replace daily signals from sleep, nutrition, exercise, stress management, and metabolic health.
Ben Greenfield · Omega-3 Fatty Acids · neutral
- Notes that omega-3s have solid research behind them for fertility.
- Recommends omega-3 fatty acids, specifically EPA and DHA, at 1 to 3 grams per day for better sperm morphology and motility, noting that sperm membranes are rich in polyunsaturated fatty acids.
- Recommends getting Omega-3 from oily fish such as sardines, anchovies, mackerel, herring, and salmon with skin.
- Discusses why fatty fish or fish oil may matter more than plant-based omega-3s if seed oils are in one's diet.
- Says that omega-3 fatty acids are a great way to feed the system and help with stress.
- Recommends testing for and replenishing omega-3 fatty acids if levels are low, as they can affect the ability to maintain or preserve muscle, especially for those on GLP-1s.
- Recommends including EPA from fatty fish or fish oil in one's diet, especially if seed oils are present in the diet.
- Notes that B vitamins and Omega-3s work as a pair to support the brain, but not independently.
- Notes that the DO-Health study showed omega-3 had good effects, and it's a supplement people commonly take.
- Mentions that omega-3, vitamin D, and exercise all had good effects in the DO-Health study.
Peter Attia · Omega-3 Fatty Acids · neutral
- Peter and Michael explore the benefits of omega-3 fatty acids for cardiovascular trials and the challenge of delivering DHA to the brain.
- Mentions that some trials showing a benefit to PUFA were confounded by the inclusion of omega-3s, and argues that the literature on omega-3s is not super strong for decreasing hard cardiovascular disease endpoints.
- Took big doses of omega-3 postpartum to help maintain when she wasn't sitting down to eat full meals.
- Mentions consuming fatty fish, specifically sardines, as part of their diet, noting their high fat and protein content.
- Peter discusses how omega-3s from fish oil impact inflammation, heart health, and brain function, as well as the strengths and limitations of current research.
- Mentions the importance of DHA omega-3 fatty acids for neuronal membranes, which are concentrated in synapses and crucial for communication between neurons.
- Highlights the importance of DHA omega-3 fatty acids for neuronal membranes and communication between neurons, as they are concentrated in synapses.
- Discusses the mfsd2a transporter, which is specific to DHA in phospholipid form, and its role in blood-brain barrier integrity, noting that animal studies show disruption of this transporter causes significant breakdown of the blood-brain barrier and loss of omega-3 in the brain.
- States that there is a very strong clinical impression that high doses of omega-3s help with dry eye, primarily from an anti-inflammatory standpoint.
- Recommends omega-3 fatty acids, specifically DHA and EPA, for brain protection, especially for individuals with the APOE4 gene, stating that they require higher doses.
Bryan Johnson · Omega-3 Fatty Acids · recommends
- Recommends Omega 3 fatty acids as a supplement for skin health, noting they are in the Blueprint stack.
- During menopause, Bryan Johnson recommends ensuring adequate omega-3s for brain health.
RAL Summary
Members OnlyTier 4 for Circulation
Tier 3 needs some study support, but no human studies on heart blood flow were given for this product's ingredients, so the evidence is thin and supports tier 4. So it is graded Tier 4, lower than the rules alone gave.
- Emerging: not enough evidence to rank higher yet.
- No human studies on this goal for its ingredients.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Cardiovascular system
Combine with: For cholesterol, pair it with agents that lower LDL: plant sterols/stanols (about 2 g/day), soluble fiber such as psyllium or beta-glucan (5-10 g/day), and bergamot extract. Red yeast rice (monitor like a med, ideally with CoQ10) and berberine can also help. Niacin may be considered under medical supervision. Adding CoQ10 or ubiquinol supports heart muscle energy, especially if on a med. Vitamin E (mixed tocopherols) can protect omega-3s from oxidation, and magnesium supports vascular health. Take the fish oil with a fat-containing meal for better absorption, and consult a doctor first if you take meds or other cardiovascular medications.
Possible side effects: No major side effects reported.
Supplement Facts
Total Omega-3 Fatty Acids 1780 mg
| Calories | 20 | |
| Total Fat | 2 g | |
| Total Omega-3 Fatty Acids | 1,780 mg | † |
Other ingredients: Bovine Gelatin, Water, Purified, Glycerin.
Directions: Suggested use: Take 2 gelcaps two times daily or as recommended by your health-care practitioner.
Barcode (UPC) 693749610014 · Label source: NIH label database · Report a label change
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