Thorne Thyroid Health Complex Review

Product Focus: Thyroid HealthAlso covers:HormonesImmune systemBrain
Tier ⓘ
Tier 4 · Rank 6
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 6 within Tier 4 for Thyroid Health; 31 of 41 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
15 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Biohacker Mentions
0 of 10

Study, Trial or Testing Result Summary

Members Only204 human studies · 60 improved

3 of these 204 human studies gave the ingredient by drip or injection, not by mouth.

204 human studies60 improved98 no effect678,592 people studied

Selenium is given at a full studied dose. In people with Hashimoto thyroiditis, pooled trials found it lowered thyroid antibodies and thyroid stimulating hormone [1][2]. In a mildly underactive thyroid, it restored normal function in 31 percent versus 3 percent of controls [3]. One review judged the evidence too weak for routine use [4]. Iodine is at a full dose. It helps mainly people who lack it, for example by shrinking iodine deficiency goitre [5]. Too much can harm the thyroid [6]. Vitamin C is near the studied dose. It lowered thyroid stimulating hormone in small studies of people on meds [7][8], but a larger placebo-controlled trial found no effect [9]. Ashwagandha, at 180 milligrams a day, is well below the 600 milligrams that helped in one trial of mildly underactive thyroid [10]. Pooled trials found little change in thyroid hormones [11]. Zinc is below the studied 30 milligrams. Pooled trials found it raised the active thyroid hormone, with low certainty [12]. Copper is also below the studied dose, and there is no good evidence that it helps [13]. Vitamin E alone did not change thyroid function [14]. Tyrosine evidence is very thin [15]. Vitamin B12 has not been shown to help [16]. Animal and cell studies are never counted.

See all 204 studies →Hide the studies

Review Totals and Summary

Members OnlyWhat buyers say

No written reviews read yet.

Biohacker Summary

Members Only0 of 10 recommend it
0 of 10 biohackers on our panel recommend it

Zinc is the main ingredient the panel spoke about, and nine of the ten talked about it: four recommend it and four others use it, while one warns about overdoing it. They take it for testosterone and prostate health, sperm health, mood and motivation, immune support alongside vitamin C, gut lining and stomach problems (in the zinc carnosine form), wound healing, and sleep. Doses given include 15 mg each morning by one panelist and 30 mg for sperm health by another, and the one who warns says too much zinc can lead to low copper. Iodine and selenium also count as main ingredients here: one panelist recommends enough iodine for thyroid hormone levels, while another warns that high doses carry a risk of thyroid autoimmune problems, and one recommends selenium for immune balance. Vitamin C, which was often paired with collagen, is a smaller ingredient in this product and was widely recommended by the panel.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Zinc · recommends
    • 31 Oct 2026 · recommends · YouTube ↗
      Recommends ensuring sufficient zinc intake because the prostate needs enough zinc for the conversion from testosterone to DHT to be smooth and optimized.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
    • 25 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Dr. Berg states that Vitamin C helps fight biofilms and is essential for making collagen in gums, teeth, and capillaries.
    • 24 Oct 2026 · recommends · YouTube ↗
      Recommends taking zinc carnosine for an ulcer or some type of gastric problem.
    • 24 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C as a cofactor, especially for collagen.
    • 23 Oct 2026 · recommends · YouTube ↗
      Emphasizes the importance of zinc for decreasing viral replication and recommends taking 40 to 60 mg every single day.
    • 23 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that high doses of vitamin C, like 2 to 4 grams, can greatly reduce inflammation and support the immune system.
    • 21 Oct 2026 · Iodine · recommends · Podcast ↗
      Recommends applying a drop of iodine and covering the skin tag with a bandage twice a day for topical skin tag removal.
    • 19 Oct 2026 · neutral · YouTube ↗
      Notes that birth control pills deplete the body of zinc, which is needed for the brain to make serotonin.
    • 18 Oct 2026 · uses · YouTube ↗
      Added zinc to his creatine product because a deficiency in zinc might make creatine not work as well.
    • 18 Oct 2026 · neutral · YouTube ↗
      Mentions that grass-fed liver is loaded with zinc.
    • 18 Oct 2026 · recommends · Facebook ↗
      Recommends zinc to enhance testosterone.
    • 18 Oct 2026 · Copper · uses · YouTube ↗
      Added copper to his creatine product because a deficiency in copper might make creatine not work as well.
    • 18 Oct 2026 · Copper · neutral · YouTube ↗
      Mentions that grass-fed liver is loaded with copper.
  • Andrew Huberman · Zinc · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Zinc carnosine to support and improve the lining of your gut.
    • 26 Oct 2026 · uses · YouTube ↗
      Notes that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 26 Oct 2026 · Tyrosine · neutral · YouTube ↗
      Mentions Tyrosine as a precursor to dopamine.
    • 22 Oct 2026 · Tyrosine · neutral · Podcast ↗
      Discusses L-Tyrosine as a neuromodulator for cognitive enhancement and focus.
    • 22 Oct 2026 · Tyrosine · stopped · YouTube ↗
      He recommends 500 mg to 1,000 mg of L-tyrosine, an amino acid precursor to dopamine, taken alone or in conjunction with alpha GPC, to increase focus without stimulant-based alertness.
    • 19 Oct 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 12 Oct 2026 · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 1 Oct 2026 · Tyrosine · uses · YouTube ↗
      Uses 500 milligrams of L-Tyrosine in capsule form, often combined with Alpha-GPC and coffee, early in the day before workouts or concentrated mental work to increase dopamine transmission for concentration and focus.
    • 1 Oct 2026 · Tyrosine · neutral · Podcast ↗
      Discusses L-Tyrosine and its relation to dopamine, also mentioning combining tools.
    • 28 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut, and he was already taking some of these ingredients separately.
    • 21 Sep 2026 · uses · YouTube ↗
      States that AG1 Pro includes zinc carnosine, which he was already taking separately, to support and improve the lining of the gut.
    • 14 Sep 2026 · uses · YouTube ↗
      Personally takes zinc carnosine, which is included in AG1 Pro to support and improve the lining of the gut.
    • 31 Aug 2026 · uses · YouTube ↗
      AG1 Pro has zinc carnosine to support and improve the lining of your gut. Some of these ingredients I personally was already taking separate from the AG1 formula.
    • 24 Aug 2026 · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of your gut.
  • Ben Greenfield · Zinc · warns
    • 29 Oct 2026 · warns · YouTube ↗
      Ben Greenfield's formulation includes 30 grams of zinc a day, taken for one week before surgery and two weeks after, as it is an important cofactor for wound healing.
    • 29 Oct 2026 · Copper · neutral · YouTube ↗
      Mentions that overshooting zinc can lead to a copper deficiency, highlighting the interplay between these elements.
    • 29 Oct 2026 · Vitamin E · neutral · YouTube ↗
      Mentions a recent study showing no significant increase in bleeding for patients on Vitamin E supplementation during open heart surgery, which was interesting for him to learn.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 15 Oct 2026 · Iodine · recommends · YouTube ↗
      Recommends taking sufficient iodine to ensure free T3 levels are right, which is important for the reverse calcium transport system.
    • 15 Oct 2026 · Selenium · recommends · YouTube ↗
      Recommends taking sufficient selenium to ensure free T3 levels are right, which is important for the reverse calcium transport system.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 10 Oct 2026 · recommends · YouTube ↗
      Emphasizes that zinc sufficiency is crucial for immunity because the thymus-derived peptide thymulin, which trains lymphocytes, requires zinc to be active.
    • 24 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
    • 23 Sep 2026 · Ashwagandha · neutral · X ↗
      Ashwagandha, taken as 120–1,000 mg for at least 6 weeks, with most studies providing a dose of 400–600 mg/d, can lower cortisol levels, improve sleep quality, and enhance cognitive resilience for athletes during challenging phases consisting of high-volume resistance training.
    • 19 Sep 2026 · recommends · YouTube ↗
      Recommends adding zinc into one's stack because it is a co-factor for enzymes involved in testosterone synthesis and sperm maturation, and zinc deficiency is a reproducible cause of low sperm count.
    • 19 Sep 2026 · neutral · Podcast ↗
      He mentions zinc as a supplement with real human data behind it for male fertility.
    • 8 Sep 2026 · neutral · X ↗
      Zinc may support both testosterone and sperm count.
    • 7 Sep 2026 · Copper · uses · X ↗
      Says Formula IQ CopperIQ Serum has stayed in their routine to close out summer strong.
  • Thomas DeLauer · Zinc · uses
    • 23 Oct 2026 · uses · YouTube ↗
      Adds zinc to their immunity duo because it helps them absorb vitamin C, considering the two together a fantastic combination for fall and winter.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 18 Oct 2026 · Vitamin B12 · recommends · YouTube ↗
      Recommends Vitamin B12 for mental health and mood, explaining its role in myelination and neurotransmitter production. They specifically recommend a liposomal and micellar form of methylcobalamin B12 for better absorption and to avoid toxicity.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends zinc, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 4 Oct 2026 · Selenium · recommends · YouTube ↗
      Recommends adding selenium to the diet, found in Brazil nuts (two or three a day), eggs, shellfish, and mushrooms, as the glutathione recycling process is very selenium dependent and it helps protect against feroptosis.
    • 4 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
    • 3 Oct 2026 · neutral · YouTube ↗
      Mentions that more zinc could be beneficial for testosterone, but it's not working on the axis that most people need help with.
    • 3 Oct 2026 · Ashwagandha · recommends · YouTube ↗
      Recommends ashwagandha extract, noting a study where 57 overweight men over 40 saw a 14.7% increase in testosterone and an 18% increase in DHEA over 16 weeks, suggesting it removes the cortisol block suppressing the entire hormonal cascade.
    • 29 Sep 2026 · Vitamin C · uses · YouTube ↗
      Takes Purity's liquid liposomal vitamin C for immune support and overall wellness, finding it easy to add to water, juice, or take straight up due to its good taste.
    • 18 Sep 2026 · neutral · Facebook ↗
      Compares zinc content, noting salmon has under 1mg while oysters have 74mg per 100g, a 70x difference.
    • 18 Sep 2026 · Vitamin C · neutral · Facebook ↗
      Compares the Vitamin C content of oranges (53mg) to guava (228mg), noting guava has 4x more.
    • 6 Sep 2026 · recommends · Instagram ↗
      Recommends keeping zinc levels topped off because it is a critical cofactor for over 300 enzymes and is important for immune cells, testosterone, and wound healing.
    • 2 Sep 2026 · recommends · YouTube ↗
      Recommends 15 mg of supplemental zinc if oysters are not realistic, but emphasizes that food source zinc is better as it comes with natural cofactors like copper and selenium.
  • Dave Asprey · Zinc · uses
    • 7 Oct 2026 · uses · YouTube ↗
      Developed a nonnano zinc sunscreen over five years, stating her skin is probably better now than it's ever been.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 11 Oct 2026 · Tyrosine · recommends · Podcast ↗
      Dave explains how L-tyrosine gives your brain the raw materials to make focus chemicals, and mentions the dose and timing that work.
    • 7 Oct 2026 · Vitamin C · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 7 Oct 2026 · Vitamin E · uses · YouTube ↗
      Dave Asprey's kids get a little bit of vitamin E every day, which helps to stabilize the bad oils they get when eating at restaurants.
    • 3 Sep 2026 · recommends · YouTube ↗
      Emphasizes the importance of having enough zinc before trying advanced longevity strategies like peptides.
    • 3 Sep 2026 · Selenium · recommends · YouTube ↗
      Emphasizes the importance of having enough selenium before trying advanced longevity strategies like peptides.
    • 3 Sep 2026 · Copper · recommends · YouTube ↗
      Emphasizes the importance of having enough copper before trying advanced longevity strategies like peptides.
    • 1 Sep 2026 · recommends · YouTube ↗
      Suggests that zinc has better safety and protective data than meds for reducing cardio respiratory risk.
    • 29 Aug 2026 · Ashwagandha · neutral · YouTube ↗
      Dave Asprey notes that ashwagandha, when taken as a real standardized extract at a real dose, genuinely lowers cortisol and shows effects on stress and sleep quality in randomized trials, but lacks polysomnography data.
    • 22 Aug 2026 · Tyrosine · uses · YouTube ↗
      Uses L-Tyrosine, an amino acid, to provide the brain with raw ingredients to make dopamine and norepinephrine, which activate the focus switch. He takes 500 mg every morning and advises starting with that dose and working up if needed, ideally on an empty stomach.
    • 20 Aug 2026 · Selenium · warns · YouTube ↗
      Warns that too much selenium increases cancer risk, becomes a toxin, and gets sequestered in tumors.
    • 18 Aug 2026 · Vitamin E · recommends · YouTube ↗
      Recommends Vitamin E as one of the most important supplements for overall health.
    • 14 Aug 2026 · Vitamin C · neutral · Podcast ↗
      Dave Asprey reflects on how new research clarifies the mechanism behind IV vitamin C's anti-cancer effect, vindicating a decades-old idea that was dismissed for the wrong reasons.
  • Dr. Mark Hyman · Zinc · uses
    • 7 Oct 2026 · uses · YouTube ↗
      Gave a patient with psoriatic arthritis a little zinc, which contributed to significant improvement in her condition.
    • 23 Oct 2026 · Ashwagandha · recommends · Facebook ↗
      Lists ashwagandha as an herb that can help lower anxiety or depression symptoms.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 7 Oct 2026 · Vitamin C · neutral · Podcast ↗
      Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
    • 7 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Mentions topical vitamin C as an antioxidant that can help skin with aging.
    • 6 Oct 2026 · Vitamin C · neutral · X ↗
      Mentions that what they do when a cold comes on is not just vitamin C.
    • 5 Oct 2026 · recommends · YouTube ↗
      Recommends ensuring adequate zinc intake on a regular basis for immune support, noting some data on zinc lozenges for early cold.
    • 5 Oct 2026 · Selenium · recommends · YouTube ↗
      Includes selenium in a formula he uses to support health during the winter season.
    • 5 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends ensuring adequate vitamin C intake on a regular basis for immune support, stating it's important for healthy immune function despite mixed data on its effectiveness for colds.
    • 30 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that vitamin C was the very first vitamin discovered, isolated, and synthesized in 1932, and its deficiency caused scurvy.
    • 22 Sep 2026 · recommends · Instagram ↗
      Recommends correcting nutrient deficiencies with zinc.
    • 14 Sep 2026 · recommends · Facebook ↗
      Recommends nutrient-dense foods rich in zinc, such as pumpkin seeds and oysters, to reduce inflammation.
    • 14 Sep 2026 · Selenium · recommends · Facebook ↗
      Recommends nutrient-dense foods rich in selenium, such as Brazil nuts and sardines, to reduce inflammation.
    • 14 Sep 2026 · Vitamin C · recommends · Facebook ↗
      Recommends nutrient-dense foods rich in vitamin C, such as guavas and parsley, to reduce inflammation.
  • Dr. Rhonda Patrick · Zinc · recommends
    • 29 Sep 2026 · recommends · YouTube ↗
      Notes that not getting enough zinc can affect testosterone, as zinc is very important for testosterone synthesis.
    • 28 Sep 2026 · recommends · YouTube ↗
      Recommends men take a 30 milligram zinc supplement for sperm health when preparing for IVF.
    • 25 Aug 2026 · Vitamin E · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 25 Aug 2026 · Vitamin C · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 21 Aug 2026 · neutral · Instagram ↗
      Discusses findings from a meta-analysis on zinc supplementation, noting it improved insulin resistance, inflammation, and oxidative stress in people with diabetes or prediabetes, and explains its biological role in the pancreas.
    • 5 Jun 2026 · recommends · Instagram ↗
      Recommends nutrients like zinc for men to prioritize sperm mitochondrial health.
    • 5 Jun 2026 · Vitamin C · recommends · Instagram ↗
      Recommends nutrients like vitamin C for men to prioritize sperm mitochondrial health.
    • 4 May 2026 · Vitamin C · uses · YouTube ↗
      Dr. Rhonda Patrick's daughter chugs an Emergency fizzy drink in the morning to ensure she gets some vitamin C and micronutrients before school.
    • 5 Feb 2026 · Vitamin E · recommends · Facebook ↗
      Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
    • 5 Feb 2026 · Vitamin C · recommends · Facebook ↗
      Choosing a multivitamin that includes lutein and zeaxanthin ensures you get meaningful amounts every day.
    • 9 Jan 2026 · Vitamin E · neutral · Facebook ↗
      Notes that ~60% of Americans are low in vitamin E.
    • 9 Jan 2026 · Vitamin C · neutral · Facebook ↗
      Notes that ~35% of Americans are low in vitamin C.
    • 29 Dec 2025 · Vitamin C · recommends · X ↗
      Recommends increasing vitamin C intake if concerned about skin aging, noting it is an essential cofactor for collagen synthesis.
    • 17 Dec 2025 · recommends · Instagram ↗
      Recommends Zinc, stating it is a critical mineral required for testosterone production and that supplementation corrects deficiency-related low testosterone.
  • Siim Land · Selenium · recommends
    • 5 Aug 2026 · recommends · YouTube ↗
      States that deficiencies in nutrients such as selenium can impair normal immune regulation.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 14 Oct 2026 · Copper · neutral · Instagram ↗
      Mentions that copper is a mineral necessary for making collagen.
    • 7 Oct 2026 · Ashwagandha · recommends · Instagram ↗
      Recommends Ashwagandha for stress, sleep and performance, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · Ashwagandha · neutral · X ↗
      Lists Ashwagandha as one of 15 supplements backed by human studies.
    • 30 Sep 2026 · Vitamin C · neutral · X ↗
      Lists sauerkraut and fruit as sources of Vitamin C.
    • 6 Sep 2026 · Vitamin C · neutral · X ↗
      Notes that Vitamin C is one of several supplements with human evidence.
    • 6 Sep 2026 · Ashwagandha · neutral · X ↗
      Notes that Ashwagandha is one of several supplements with human evidence.
    • 5 Aug 2026 · Zinc · recommends · YouTube ↗
      States that deficiencies in nutrients such as zinc can impair normal immune regulation.
    • 27 Jul 2026 · Vitamin C · neutral · X ↗
      Notes that researchers found vitamin C alleviates ferro-aging, a process of iron overload and lipid peroxidation that drives aging, and that it directly inhibited ACSL4, a protein driving ferro-aging.
    • 27 Jul 2026 · Vitamin C · neutral · X ↗
      States that Vitamin C has a central role in aging and longevity, and that in monkeys, oral vitamin C slowed ovarian aging during a 3.3-year study.
    • 27 Jul 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is one of the most important vitamins for staying healthy and aging well, and that intakes of 200 to 400 mg a day from food or supplements largely saturates plasma and neutrophils in most healthy adults. He also recommends spreading out the vitamin C across the day to avoid oversaturation.
    • 27 Jul 2026 · Vitamin E · neutral · YouTube ↗
      Notes that oral vitamin E and C supplementation has been noted to increase the dose of UVB radiation from the sun needed to cause redness of the skin, suggesting increased resilience against sun damage. He also mentions a trial where a combination of slow-release vitamin C and vitamin E decreased the progression of carotid atherosclerosis in men.
  • Bryan Johnson · Zinc · uses
    • 4 May 2026 · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 14 Apr 2026 · uses · X ↗
      Takes 15 mg of Zinc in the morning.
    • 2 Apr 2026 · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 2 Apr 2026 · Copper · uses · X ↗
      Takes 2 mg of Copper in the morning for longevity.
    • 8 Jul 2025 · Ashwagandha · uses · YouTube ↗
      Drinks his Blueprint longevity mix with additional morning supplements, including ashwagandha.
    • 5 Jun 2025 · Ashwagandha · uses · YouTube ↗
      States that Blueprint Ashwagandha can be used to stabilize mood.
    • 5 Jun 2025 · Vitamin B12 · uses · YouTube ↗
      States that Blueprint essential capsules and soft gels are packed with key vitamins and minerals needed for strong bone health.
    • 3 Feb 2025 · Vitamin C · neutral · YouTube ↗
      Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
    • 8 Jan 2025 · Vitamin C · uses · YouTube ↗
      Applies vitamin C after showering.
    • 20 Feb 2024 · Ashwagandha · uses · YouTube ↗
      Mentions that Ashwagandha is included in the LA Longevity Mix, which condenses his 100 daily pills into a drink.
    • 16 Dec 2023 · uses · YouTube ↗
      Bryan Johnson's baseline measurements showed low zinc, which was easy to fix by adjusting her protocol and supplements.
    • 7 Dec 2023 · Ashwagandha · neutral · Instagram ↗
      Mentions ashwagandha as a potential therapy that could positively influence sperm health.
    • 26 Sep 2023 · Vitamin C · uses · YouTube ↗
      Takes 250 milligrams of Vitamin C.
    • 27 Jul 2023 · Ashwagandha · uses · YouTube ↗
      Mentions ashwagandha as an ingredient in his 'bag of goodies', indicating he uses it.
  • Peter Attia · Zinc · recommends
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 1 Jun 2026 · Ashwagandha · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 17 Nov 2025 · Iodine · warns · Podcast ↗
      Discusses the dangers of supplementing with high levels of iodine.
    • 16 Nov 2025 · Iodine · warns · YouTube ↗
      Warns that high-dose iodine supplementation carries a risk of autoimmune thyroid disease, citing increased incidence in Japan due to higher dietary iodine intake.
    • 16 Nov 2025 · Selenium · neutral · YouTube ↗
      Notes that several studies show patients taking selenium can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 30 Oct 2025 · Ashwagandha · uses · YouTube ↗
      Finds ashwagandha a little bit helpful for sleep, though notes it may not be for everyone.
    • 27 Oct 2025 · Ashwagandha · neutral · YouTube ↗
      Finds ashwagandha "a little bit helpful" for sleep, but notes that it may not be for everyone.
    • 3 Jul 2025 · Vitamin C · stopped · YouTube ↗
      Recommends vitamin C as an important molecule for skin, noting its role as a precursor for collagen synthesis, a powerful antioxidant, and a regulator of complexion for even skin tone.
    • 29 Jun 2025 · Vitamin C · stopped · YouTube ↗
      Tried a vitamin C serum mixed with ferulic acid but stopped using it because she hated the smell. She notes that topical application of vitamin C far exceeds the levels achievable by ingestion for skin benefits.
    • 30 Mar 2025 · Ashwagandha · neutral · YouTube ↗
      Finds ashwagandha a little bit helpful for sleep, but notes it may not be for everyone.
    • 23 Mar 2025 · Ashwagandha · warns · YouTube ↗
      States that the data for ashwagandha are weak.
    • 17 Mar 2025 · Ashwagandha · neutral · Instagram ↗
      Discusses the current evidence for ashwagandha's effects on sleep, stress, and anxiety.
    • 16 Mar 2025 · Ashwagandha · neutral · YouTube ↗
      Mentions ashwagandha as an evergreen shrub historically used in traditional Indian medicine for indications such as sleep, stress, and immune health.
    • 9 Sep 2024 · Vitamin B12 · neutral · YouTube ↗
      Notes that deficiencies in certain vitamins and minerals, such as B12, can be a cause of hair loss in women.

RAL Summary

Members OnlyTier 4 for Thyroid Health

Some ingredients, mainly selenium, iodine and zinc, have human study support for thyroid measures, but no reviews have been counted. That keeps the product at the emerging tier.

Take 4 servings a day (8 capsules) to match the dose that worked in the studies.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 98 of the 204 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Endocrine system, Immune system, Nervous system

Possible side effects: In the studies, high iodine intake enlarged the thyroid in healthy men and slowed recovery after thyroid surgery. One selenium review reported a higher risk of side effects, though another found no more than with control.

Supplement Facts

Ashwagandha Extract 90 mg · Copper 500 mcg · Iodine 225 mcg
Supplement Facts
Serving Size 2 Capsules
Servings Per Container 60
Amount Per Serving% Daily Value
Ashwagandha Extract (Withania somnifera)90 mg†
Copper500 mcg
Iodine225 mcg
Selenium100 mcg
L-Tyrosine500 mg†
Vitamin B12100 mcg
Vitamin C200 mg
Vitamin E67 mg
Zinc5 mg
† Daily Value not established.

Other ingredients: Leucine, Silicon Dioxide, Hypromellose (derived from cellulose) capsule.

Directions: Take 2 capsules two times daily or as recommended by your health-care professional.

Label source: Reverseagelab · Report a label change

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Our articles on this subject

Graded November 5, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.