AB American Biologics Ultra Hepa Trope II Review

Ultra Hepa Trope II is a liver performance nutrient supplement sold by AB American Biologics, listed in the Dietary Supplement Label Database with DSLD ID 203820. The label describes it as a vegetarian capsule product with a net content of 120 vegetarian capsules (4.23 oz, 120 grams). The suggested use is 4 capsules per day with meals, which equals one serving, and each container holds 30 servings. Each serving supplies Vitamin B6 as pyridoxine hydrochloride, magnesium as magnesium glycinate, and molybdenum as sodium molybdate, along with Siliphos milk thistle extract, alpha-lipoic acid, trimethylglycine, glutathione, NAC, glycine, glutamine, taurine, and dandelion root concentrate. The label states the product is free of gluten, yeast, wheat, corn, dairy, sugar, starch, and artificial coloring or flavoring, and it is classed for adults. The maker says the formula was designed to nutritionally support the body's renewal of liver tissue and was formulated by Parris M. Kidd, PhD. The product is manufactured in the USA exclusively for American Biologics in Chula Vista, California. The label carries the standard FDA disclaimer that the statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure or prevent any disease. Storage is in a cool, dry place, and the label advises keeping the product out of the reach of children. Pregnant or nursing mothers are told to consult a physician before use.

Product Focus: Liver HealthAlso covers:DigestionMetabolism
Tier ⓘ
Tier 4 · Rank 12
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 12 within Tier 4 for Liver Health; 36 of 40 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
35 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Biohacker Mentions
10 of 10

Study, Trial or Testing Result Summary

Members Only213 human studies · 91 improved

45 of these 213 human studies gave the ingredient by drip or injection, not by mouth.

213 human studies91 improved84 no effect108,050 people studied

Silymarin, the milk thistle extract in Siliphos, is the best-supported ingredient here at a full dose: a pooled analysis of 55 trials in people with liver injury found it lowered two main liver enzymes [1], and silybin with phosphatidylcholine and vitamin E improved liver enzymes and liver tissue in fatty liver over 12 months [2]. Older reviews found no change in deaths or liver tissue, though most of those trials were low quality [3]. N-acetylcysteine helps mainly in hospital care of serious liver failure [4], but 2400 milligrams a day by mouth did not improve fatty liver [5]. Taurine at 2 grams a day lowered liver enzymes after liver transplant [6]. Alpha-lipoic acid did not change liver enzymes in a pooled analysis of fatty liver trials [7]. Trimethylglycine lowered liver enzymes at 2 grams or more a day [8], but betaine alone did not in a pooled analysis [9]. Magnesium is below the studied dose and showed no clear liver benefit [10]. Glycine was studied at a dose based on body weight, far above this amount, and without a placebo group [11]. Dandelion was tested only inside a multi-herb formula [12]. Vitamin B6 alone did not help in cirrhosis [13]. Animal and cell studies are never counted.

See all 213 studies →Hide the studies

Review Totals and Summary

Members OnlyWhat buyers say

Not available. I found no customer reviews for this product during the search, so I can't responsibly describe qualitative feedback themes.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

The statements list no main ingredient for this product, only smaller ingredients, and magnesium drew the most comment, with all ten panelists mentioning it. Most of the panel recommends or uses it, mainly for sleep, but also for blood pressure, muscle function, workout performance and bone support; the forms named were glycinate, threonate (400 mg before bed) and electrolyte drinks, and one panelist pairs it with vitamins D3 and K2. Two panelists warned that labels can overstate how much real magnesium a supplement contains, and one said it does not fix waking in the night. Glycine, also a smaller ingredient in this product, is used by two panelists at 2 grams before bed for sleep, and others recommend it for longevity, gut repair and body fat, while glutathione, another smaller ingredient, got a few mentions for detox and post-surgery use. Nobody said they stopped taking any of these.}

See all 10 biohackers →Hide the biohackers
  • Dr. Mark Hyman · Magnesium · uses
    • 1 Nov 2026 · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 28 Oct 2026 · Glutathione · recommends · YouTube ↗
      Recommends Rosen Nutrition Liposomal Glutathione to support immunity through colder months, noting it helps maintain healthy immune cell function, supports natural detoxification, and neutralizes free radicals.
    • 21 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 19 Oct 2026 · Glutathione · neutral · YouTube ↗
      Mentions that sulforaphane helps the body make glutathione, an amazing nutrient that helps the body get rid of toxins.
    • 14 Oct 2026 · recommends · TikTok ↗
      Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
    • 7 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 30 Sep 2026 · uses · YouTube ↗
      Has recommended magnesium breakthrough from bioptimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
    • 22 Sep 2026 · recommends · Instagram ↗
      Recommends correcting nutrient deficiencies with magnesium.
    • 16 Sep 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advance 10 from BiOptimizers, which has 10 bioavailable forms of magnesium and more elemental magnesium, as part of his evening routine for sleep, muscle recovery, and metabolic health.
    • 9 Sep 2026 · uses · YouTube ↗
      Has recommended Magnesium Breakthrough from Bio Optimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
    • 9 Sep 2026 · Glutathione · uses · YouTube ↗
      Used a lot of intravenous glutathione to help him detoxify and recover from chronic fatigue.
    • 2 Sep 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advance 10 from Bio Optimizers, which contains 10 bioavailable forms of magnesium, as it plays a critical role in sleep recovery, stress regulation, and muscle function, and has become part of his evening routine, especially during periods of travel, training, and higher stress.
    • 2 Sep 2026 · Glutamine · neutral · YouTube ↗
      Mentions glutamine as something that might be helpful for gut repair.
  • Dave Asprey · Magnesium · neutral
    • 31 Oct 2026 · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 24 Oct 2026 · Glutathione · recommends · Facebook ↗
      Recommends detoxing with glutathione.
    • 17 Oct 2026 · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 29 Sep 2026 · Glutathione · recommends · YouTube ↗
      Has always recommended glutathione during pregnancy and would feel good taking it, even though he does not make a glutathione product.
    • 27 Sep 2026 · recommends · Podcast ↗
      Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
    • 25 Sep 2026 · Taurine · neutral · Podcast ↗
      Dave Asprey explains that a 2017 study in rats found taurine pretreatment reduced several behavioral and biochemical effects of chronic unpredictable stress, but notes this does not show that taurine treats depression in humans.
    • 20 Sep 2026 · Glutathione · recommends · Podcast ↗
      Discusses glutathione as part of a detox protocol for mold-related brain damage.
    • 18 Sep 2026 · Taurine · neutral · YouTube ↗
      Mentions that taurine, a common longevity molecule, affects the sense of smell, but they do not know why it works.
    • 16 Sep 2026 · Glutathione · recommends · YouTube ↗
      Suggests taking glutathione during occasional drinking to lessen the negative effects of alcohol.
    • 7 Sep 2026 · uses · Instagram ↗
      Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
    • 5 Sep 2026 · recommends · YouTube ↗
      Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
    • 5 Sep 2026 · Glycine · recommends · YouTube ↗
      Recommends GlyNAC (glycine and NAC together) as very affordable amino acids that he would bet his coffee on if he had to choose just one thing for longevity, as they help the body make glutathione, the master antioxidant.
    • 3 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
  • Siim Land · Glycine · recommends
    • 31 Oct 2026 · recommends · Instagram ↗
      Suggests that a higher glycine to methionine ratio appears to preferentially target visceral fat and improve insulin sensitivity.
    • 29 Oct 2026 · recommends · Instagram ↗
      Recommends pairing NAC with glycine to support antioxidant activity in your sleep.
    • 26 Oct 2026 · recommends · YouTube ↗
      Believes glycine is the best longevity supplement and encourages viewers to learn more about its longevity benefits.
    • 25 Oct 2026 · recommends · Instagram ↗
      States that Glycine can be a useful addition for some people for sleep.
    • 25 Oct 2026 · Magnesium · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 21 Oct 2026 · uses · YouTube ↗
      Increased his glycine supplementation to 10g a day, noting that it balances methionine and improves blood sugar and glycation.
    • 19 Oct 2026 · uses · YouTube ↗
      Personally uses glycine for its health benefits, including glutathione, blood sugar glycation, and potentially sleep, and notes that it appears to have some autophagy benefits by increasing autophagy through its role in methionine metabolism.
    • 14 Oct 2026 · neutral · Instagram ↗
      Notes that glycine is one of the most important building blocks for collagen synthesis, making up 30% of collagen, and that 12g of glycine a day is needed for collagen turnover.
    • 13 Oct 2026 · uses · Instagram ↗
      Increased his glycine intake as part of an experimental amino acid strategy.
    • 13 Oct 2026 · neutral · X ↗
      Retweeted a study stating that 3 g of glycine before bed helped people fall asleep faster and reach deep sleep sooner.
    • 12 Oct 2026 · uses · YouTube ↗
      Takes around 3 to 5 grams of glycine before bed, often mixed with chamomile tea, as human trials have found it can improve subjective sleep quality and shorten the time to fall asleep and enter deep sleep.
    • 12 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
    • 9 Oct 2026 · Taurine · neutral · Instagram ↗
      States that taurine supports normal muscle, nerve, and heart function, and supplement trials suggest benefits for some metabolic markers, exercise performance and blood pressure.
    • 7 Oct 2026 · Magnesium · recommends · Instagram ↗
      Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
  • Dr. Eric Berg · Magnesium · neutral
    • 30 Oct 2026 · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 28 Oct 2026 · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 25 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
    • 25 Oct 2026 · recommends · X ↗
      Recommends increasing magnesium to restore balance and support healthy blood pressure.
    • 24 Oct 2026 · recommends · Instagram ↗
      Dr. Eric Berg suggests that magnesium could help support deeper, more restful sleep.
    • 24 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Glycinate, noting that the combination of magnesium and glycine is helpful for connective tissue, sleep, and reducing stress.
    • 24 Oct 2026 · Glycine · recommends · YouTube ↗
      Recommends Glycine as a cofactor, especially for collagen.
    • 23 Oct 2026 · recommends · Instagram ↗
      Recommends taking magnesium 90 minutes to 2 hours before bedtime to support better sleep.
    • 23 Oct 2026 · recommends · YouTube ↗
      Suggests that magnesium glycinate can help support the missing 'break pads' on the nervous system, which contribute to constant pain.
    • 22 Oct 2026 · recommends · Podcast ↗
      Taking 400 mg of magnesium glycinate daily may also help support brain health during menopause.
    • 21 Oct 2026 · warns · YouTube ↗
      Warns against magnesium oxide because it is poorly absorbed, with only about 4% absorption, and can cause diarrhea, despite being commonly used in research and supplements due to its low cost.
    • 18 Oct 2026 · Glutathione · neutral · X ↗
      Avocados contain glutathione.
    • 10 Oct 2026 · Vitamin B6 · warns · Podcast ↗
      Dr. Berg lists pyridoxine hydrochloride as a synthetic vitamin to avoid.
    • 4 Oct 2026 · Vitamin B6 · recommends · Facebook ↗
      Recommends taking the active form of vitamin B6, pyridoxal-5-phosphate (P5P), for its benefits to the nervous system, including building the myelin sheath and protecting sensory nerve integrity.
  • Ben Greenfield · Glutathione · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Will do glutathione for some patients after surgery.
    • 29 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 22 Oct 2026 · Magnesium · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · Magnesium · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · Magnesium · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 16 Sep 2026 · Taurine · neutral · X ↗
      Taurine on its own isn’t particularly impressive as an ergogenic aid, but when combined with caffeine, there are significant increases in power production.
    • 3 Sep 2026 · Magnesium · recommends · YouTube ↗
      Recommends supplementing with magnesium threonate if one is low in magnesium, as it crosses the blood-brain barrier and is demonstrated to increase hippocampus plasticity, theoretically making one smarter and improving memories.
    • 25 Aug 2026 · Magnesium · uses · Facebook ↗
      Uses Magnesium Breakthrough from BIOptimizers as part of their daily stack, taking four capsules in the evening to support relaxation, recovery, and a good night of sleep.
    • 17 Aug 2026 · Magnesium · recommends · Facebook ↗
      Recommends Celtic Sea Salt's new electrolyte drink "Hydrate" for replacing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, plus magnesium, taurine, and potassium.
    • 15 Aug 2026 · Magnesium · warns · YouTube ↗
      Had heart palpitations when he was really overdoing magnesium, not knowing what he was taking.
    • 8 Aug 2026 · Magnesium · recommends · YouTube ↗
      Recommends taking magnesium as a co-factor to increase vitamin D absorption.
    • 13 Jun 2026 · Magnesium · neutral · X ↗
      Notes a new study indicating that magnesium is a core dietary antioxidant closely associated with a reduced risk of accelerated biological aging.
    • 16 May 2026 · Glycine · uses · YouTube ↗
      Mentions Dr. James Di Nicolantonio's claim that glycine, at 5 to 6 grams, can help protect cell membranes against damage from oxidized oils, citing rodent studies.
    • 9 May 2026 · uses · YouTube ↗
      Was advised by a doctor to take 5 ml of liposomal glutathione daily for as long as he has a breath, and he agreed to take it daily. He notes that some people don't do well with oral glutathione due to sulfur sensitivities.
  • Dr. Rhonda Patrick · Magnesium · neutral
    • 29 Oct 2026 · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 16 Oct 2026 · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 12 Oct 2026 · Taurine · neutral · YouTube ↗
      Mentions that taurine depletion is a concern raised in long-term animal studies regarding Beta Alanine, though not observed in human trials, and notes that one can supplement with taurine, which is a beneficial compound.
    • 29 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 28 Sep 2026 · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 7 Sep 2026 · Alpha-Lipoic Acid · neutral · YouTube ↗
      Describes alpha-lipoic acid as a short-chain fatty acid produced in mitochondria and found in various foods. They highlight its role as a cofactor in mitochondrial energy production and biogenesis, its strong antioxidant capabilities, and its ability to regenerate vitamins C and E and glutathione. They also mention its anti-inflammatory effects, its role in chelating metal ions like iron and copper, and its ability to reduce advanced glycation end products, which is beneficial for people with diabetes.
    • 2 Sep 2026 · neutral · Facebook ↗
      States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
    • 21 Aug 2026 · Glutathione · neutral · TikTok ↗
      Discusses the truth about glutathione supplements.
    • 10 Aug 2026 · neutral · Facebook ↗
      States that magnesium may help modestly lower blood pressure by playing an important role in regulating vascular tone and influencing calcium signaling, with studies showing a reduction in systolic and diastolic blood pressure by 2 mmHg at a dose of around 370 mg/day for about 3 months.
    • 10 Aug 2026 · recommends · X ↗
      Recommends considering magnesium to improve mood.
    • 31 Jul 2026 · Glutamine · uses · TikTok ↗
      Supplements with glutamine.
    • 28 Jul 2026 · recommends · Facebook ↗
      Recommends Magnesium, stating that roughly half of Americans don’t get enough and it is a cofactor for over 300 biological processes, including DNA repair and energy production.
    • 14 Jul 2026 · Glutamine · uses · X ↗
      Always packs Glutamine when traveling, taking a baseline of 5 g/day and increasing to 15-20 g/day when sleep-deprived or exposed to illness, as it is an important fuel source for immune function.
    • 29 Jun 2026 · neutral · Facebook ↗
      Mentions that kale delivers magnesium, a micronutrient many diets fall short on.
  • Thomas DeLauer · Magnesium · uses
    • 28 Oct 2026 · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 27 Oct 2026 · Glycine · neutral · YouTube ↗
      Explains that glycine is critical for collagen synthesis, which supports the intestinal wall, and deficiency can slow down the repair process.
    • 27 Oct 2026 · Glutamine · neutral · YouTube ↗
      States that glutamine is the primary fuel source for intestinal cells, and its availability is crucial for the integrity of the gut barrier.
    • 26 Oct 2026 · Glycine · recommends · YouTube ↗
      Explains that the body needs roughly 10g more of glycine per day than a typical modern diet provides, and that this deficit can lead to issues with creatine production, connective tissue repair, and sleep. He recommends increasing glycine intake.
    • 24 Oct 2026 · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 22 Oct 2026 · Taurine · recommends · YouTube ↗
      Recommends taurine, stating it raises the stress threshold, acts as a GABA and glycine receptor modulator, and protects neurons from stress, ultimately lowering cortisol release.
    • 16 Oct 2026 · Glutamine · recommends · YouTube ↗
      Recommends supplementing with glutamine for a calming effect, especially when experiencing high stress, injury, illness, or increased training volume, as it acts as a precursor to GABA and helps the body produce more of it.
    • 14 Oct 2026 · Glycine · uses · YouTube ↗
      Shifts towards glycine when cutting to keep their nervous system calm through the deficit.
    • 14 Oct 2026 · Glutamine · uses · YouTube ↗
      Loads up on extra glutamine during muscle building phases.
    • 12 Oct 2026 · Glycine · neutral · YouTube ↗
      Explains that glycine is a critical amino acid for glutathione production, and the body often has a significant shortage of it, with creatine synthesis consuming a large amount of available glycine.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 6 Oct 2026 · neutral · YouTube ↗
      Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
    • 4 Oct 2026 · Glycine · recommends · YouTube ↗
      Recommends glycine, either from supplements or food sources like bone broth, collagen peptides, and chicken skin, to help build up glutathione.
  • Andrew Huberman · Magnesium · neutral
    • 22 Oct 2026 · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 13 Aug 2026 · Glutathione · neutral · YouTube ↗
      Dr. Gottfried looks at glutathione in nutritional testing, considering it an important lever.
    • 7 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 7 Aug 2026 · Glycine · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 27 Jul 2026 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 20 Jul 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 20 Jul 2026 · recommends · YouTube ↗
      Confirms that magnesium is absolutely important for cognitive function, noting studies show those with lower magnesium intakes tend to perform less well on cognitive function tests, and it's related to brain changes over time and dementia risk.
    • 20 Jul 2026 · Glycine · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 13 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 13 Jul 2026 · Glycine · uses · X ↗
      Takes 2 grams of Double Wood Glycine before bed for sleep.
    • 12 Jul 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate from Double Wood before bed for sleep.
    • 12 Jul 2026 · Glycine · uses · X ↗
      He takes 2 grams of Glycine before bed for sleep.
    • 6 Jul 2026 · uses · X ↗
      Takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 6 Jul 2026 · Glycine · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
  • Bryan Johnson · Glycine · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 22 Oct 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 15 Aug 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 4 May 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 4 May 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 2 May 2026 · uses · X ↗
      He takes 2 g of Glycine before bed for sleep.
    • 2 May 2026 · Magnesium · uses · X ↗
      He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 21 Apr 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 21 Apr 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 15 Apr 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 15 Apr 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 14 Apr 2026 · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 14 Apr 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
  • Peter Attia · Magnesium · neutral
    • 1 Jun 2026 · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 1 Jun 2026 · Glycine · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 15 Sep 2025 · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 20 Jul 2025 · Glycine · neutral · YouTube ↗
      Mentions that they also see positive effects of glycine, among other things.
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
    • 6 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium for optimizing bone mineral density, suggesting a daily intake of 300 to 500 milligrams as a minimum, but personally aims for about a gram.
    • 15 Nov 2024 · Taurine · neutral · YouTube ↗
      Mentions that taurine supplementation in mice and other species appears to prolong life, referencing V.J. Adav's work, but notes that it is unclear if the same applies to humans.
    • 19 Aug 2024 · Taurine · neutral · YouTube ↗
      Mentions that taurine supplementation in mice and some other species appears to prolong life in VJ Addev's work, but it's unclear if the same applies to humans.
    • 7 Jul 2024 · recommends · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede the metabolism of vitamin D because magnesium is a cofactor in its enzymatic conversion.
    • 1 Jul 2024 · uses · YouTube ↗
      Takes a hardline view that most people do not have adequate or optimal levels of magnesium, and suboptimal levels will impede vitamin D metabolism because magnesium is a co-factor in the enzymatic conversion of vitamin D.
    • 20 Jun 2024 · Glycine · neutral · YouTube ↗
      Mentions that collagen tends to be rich in glycine, among other amino acids.
    • 20 May 2024 · uses · YouTube ↗
      Takes magnesium as a straightforward supplement.
    • 28 Feb 2024 · neutral · YouTube ↗
      Mentions that magnesium intake is often super low and impactful on testosterone levels.

RAL Summary

Members OnlyTier 4 for Liver Health

Some human studies support ingredients such as milk thistle extract and N-acetylcysteine, but much of the evidence is mixed or comes from hospital settings, and there are no customer reviews, so the tier stays at emerging.

Take 4 servings a day (16 capsules) to match the dose that worked in the studies.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 84 of the 213 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Digestive system, Metabolic system

Combine with: For fast heartburn relief, pair with a true acid-neutralizing option such as calcium carbonate chewables or a sodium alginate/bicarbonate formula (e.g., Gaviscon-type), which forms a barrier against reflux. For longer-term esophageal and stomach lining comfort, consider DGL licorice, zinc-carnosine, or aloe vera juice. To support the liver focus of this product, milk thistle (silymarin), NAC, and B-complex vitamins are synergistic. Digestive bitters or betaine HCl should be used cautiously and generally avoided during active heartburn. Consult a healthcare professional if heartburn occurs frequently.

Possible side effects: Betaine raised total and bad cholesterol in some studies, and very high doses of vitamin B6 were linked to raised liver enzymes; no reviews were available to add more.

Supplement Facts

Vitamin B6 25 mg · Magnesium 50 mg · Molybdenum 100 mcg
Supplement Facts
Serving Size 4 Capsule(s)
Servings Per Container 30
Amount Per Serving% Daily Value
Vitamin B625 mg
Magnesium50 mg
Molybdenum100 mcg
Siliphos240 mg†
Alpha-Lipoic Acid300 mg†
Trimethylglycine500 mg†
Glutathione50 mg†
NAC400 mg†
Glycine100 mg†
Glutamine200 mg†
Taurine1,000 mg†
Dandelion root concentrate100 mg†
† Daily Value not established.

Other ingredients: Hydroxypropyl Methylcellulose, Silicon Dioxide, Magnesium Stearate, Gum Acacia.

Directions: Recommended use: As an adult dietary supplement, take 4 capsules per day with meals, or as directed by a healthcare practitioner.

Barcode (UPC) 690290530129 · Label source: NIH label database · Report a label change

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Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.