Absonutrix S-Acetyl L-Glutathione Review
This eBay listing sells the Absonutrix S-Acetyl L-Glutathione 100 mg per Serving product in a 4 oz liquid bottle, stated as containing 200 servings. The item specifics list the brand as Absonutrix LLC, the formulation as liquid, the country of origin as the United States, and the UPC as 685167905100. The condition is listed as new, and the quantity shows more than 10 available. The listing is sold by the seller fucoidanking, who is shown with 100% positive feedback, 639 items sold, and joined in July 2015. The gallery includes several photos: a blue bottle with a white label and navy cap that states 12 oz per serving, a blue bottle with a white cap labelled 100 mg per serving, a white 4 oz bottle with a gluten-free supplement facts label, and a white 4 oz liquid bottle with 200 servings and a certificate of conformity. The page's seller item description section is blank, so no ingredient list, directions, or detailed product claims are given on this page. The page reports the item as located in Colfax, North Carolina, with seller-stated shipping that may not reach France, delivery that varies, and no returns accepted. The 250 ratings shown beside the seller name are seller feedback rather than product star ratings, so no product review histogram or written product reviews are available on this page.
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Study, Trial or Testing Result Summary
Members Only4 human studies · 3 improved
2 of these 4 human studies gave s-acetyl glutathione by drip or injection, not by mouth.
At two servings a day, the dose members are told to take, this product gives what the research counts as a full dose of S-acetyl glutathione. None of the studies below tested the S-acetyl form itself, and none measured biological age directly. In a six-month placebo-controlled trial of 54 healthy adults, plain oral glutathione raised blood glutathione levels and improved the balance of oxidized to protective glutathione, which points to less oxidative stress. Levels went back to baseline one month after stopping [1]. A large review of 194 studies found that glutathione taken by mouth or put on the skin improved skin brightness, pigmentation and hydration and lowered oxidative stress markers. Injections raised levels quickly, but the effects were short-lived and raised safety concerns [2]. In 44 postmenopausal women, glutathione with citrulline for four weeks improved blood vessel function compared with placebo, but no aging markers were measured [3]. Weekly glutathione injections gave no benefit in 24 autistic children, but that trial did not study aging [4]. Overall, glutathione may lower oxidative stress, but direct proof that it reverses aging is lacking. Animal and cell studies are never counted.
See all 4 studies →Hide the studies
- A review of 194 studies found that topical and oral glutathione improved skin pigmentation, brightness, hydration and oxidative stress markers, while injections raised levels quickly but had short-lasting effects and safety concerns.Glutathione in Skin Aging and Tissue Regeneration: A Systematic Review of Molecular Mechanisms, Redox Modulation, and Bi…
- In 54 healthy adults taking 250 or 1,000 mg of oral glutathione daily for 6 months, glutathione levels in blood rose and the oxidized-to-reduced glutathione ratio fell, and levels returned to baseline after a 1-month washout.Randomized controlled trial of oral glutathione supplementation on body stores of glutathione.
- In 44 healthy postmenopausal women, 4 weeks of citrulline plus glutathione improved blood vessel dilation and lowered blood pressure reactions to cold stress compared with placebo, but no aging markers were measured.Combined Citrulline and Glutathione Supplementation Improves Endothelial Function and Blood Pressure Reactivity in Postm…
- In 24 autistic children given weekly glutathione injections for 8 weeks, there were no differences in behavior or biologic measures compared with placebo.Glutathione, Vitamin C, and Cysteine Use in Autistic Children With Disruptive Behavior: A Double-Blind, Placebo-Controll…
Review Totals and Summary
Members Only1 reviews
No customer reviews for Absonutrix S-Acetyl L-Glutathione could be found. The eBay listing shows none, and the Amazon page text I could access contained no review content. I can't extract genuine themes without making them up. For context only, reviews of other S-acetyl glutathione products (for example Nutricost capsules on iHerb) are generally positive. Reviewers there describe it as well absorbed and as feeling good after use. One reviewer reported less of a "poisoned" feeling and better venous flow. These comments are about a different brand, so they say nothing reliable about Absonutrix's taste, mixability, value or results. To get real feedback, check the Amazon listing (ASIN B0BXZ5N55F) directly.
Biohacker Summary
Members Only4 of 10 recommend it
Glutathione gets a mixed but mostly favorable hearing from the panel: four of the ten recommend it outright, while the rest stay neutral or point out limits. People take it mainly for detox, as the body's master antioxidant, for immune support, and to ease the effects of alcohol or mold exposure. The forms named most often are liposomal, which several say absorbs better, plus intravenous and nebulized versions, and one panelist uses a daily reduced glutathione powder; the only dose given is 5 ml of liposomal glutathione daily. Some pair it with sulforaphane, glycine or NAC to help the body make its own, and one panelist uses it alongside other mold strategies. Cautions include one warning that swallowed pills are digested and ineffective, a note that some people with sulfur sensitivity do poorly on oral forms, a comment that human evidence for hangovers is thin, and a statement that it has no effect on skin anti-aging.
See all 9 biohackers →Hide the biohackers
Ben Greenfield · Glutathione · uses
- Will do glutathione for some patients after surgery.
- Was advised by a doctor to take 5 ml of liposomal glutathione daily for as long as he has a breath, and he agreed to take it daily. He notes that some people don't do well with oral glutathione due to sulfur sensitivities.
- Mentions Dr. Patel developed transdermal glutathione, and later a transdermal GHK copper peptide, using similar technology for better absorption.
- Recommends glutathione to provocate mold, as part of a triple mold combination strategy.
- Describes glutathione as the master antioxidant, noting that our needs for it triple as we age.
- Warns that using high-dose antioxidants like glutathione directly before or after a hyperbaric session is not a great idea, as it could impair some of the effects by reducing reactive oxygen species.
- Recommends taking glutathione or NAC with AHCC, as they synergize well due to AHCC's liver benefits.
- Ben Greenfield's guest was taking glutathione in a very unique topical form as part of their protocol.
- Uses a transdermal glutathione spray called Gluteril, doing eight sprays in the morning and eight sprays in the evening while in India, which is four times his normal dose, for its antioxidant effects on mitigating air pollution damage.
- Ben Greenfield recommends transdermal glutathione over oral glutathione for lung health, as it bypasses breakdown and directly increases availability in the bloodstream.
Dr. Mark Hyman · Glutathione · recommends
- Recommends Rosen Nutrition Liposomal Glutathione to support immunity through colder months, noting it helps maintain healthy immune cell function, supports natural detoxification, and neutralizes free radicals.
- Mentions that sulforaphane helps the body make glutathione, an amazing nutrient that helps the body get rid of toxins.
- Used a lot of intravenous glutathione to help him detoxify and recover from chronic fatigue.
- Recommends glutathione for COVID-19, stating that he published the first article on its benefits in April 2020 and none of his patients died from COVID-19 while blocking the inflammatory pathway with it.
- Leans on glutathione, in oral, liposomal, IV, or nebulized forms, as an important molecule for detoxification, especially for neurologic symptoms during a Herxheimer reaction.
- States that cabbage family vegetables and onions induce glutathione, the master antioxidant in the cells, and help support detoxification.
- Uses Roe's liposomal glutathione because it's designed to help the body absorb and use it, supporting detoxification and protecting cells from damage.
- Uses Roe's liposomal glutathione because it is designed to help the body absorb and use this master antioxidant and detoxifier, which supports the liver, neutralizes toxins, and protects cells from damage.
- Explains that glutathione is the body's main detoxifying compound and it comes from amino acids, highlighting its role in detoxification.
- Recommends using liposomal glutathione as part of a detoxification protocol for at least 3 months.
Dave Asprey · Glutathione · recommends
- Recommends detoxing with glutathione.
- Has always recommended glutathione during pregnancy and would feel good taking it, even though he does not make a glutathione product.
- Discusses glutathione as part of a detox protocol for mold-related brain damage.
- Suggests taking glutathione during occasional drinking to lessen the negative effects of alcohol.
- Dave Asprey warns that swallowing glutathione pills is ineffective because it's digested, and suggests giving the body raw materials like glycine and NAC to make it instead, which is also cheaper.
- Emphasizes the importance of healthy glutathione in the liver for getting toxins out, even if one eats and breathes no toxins.
- Recommends glutathione as the body's master antioxidant, which helps the liver process toxins and cells defend against oxidative stress, especially when mycotoxins are present.
- Explains why glutathione is known as the body’s master antioxidant and why it plays a critical role in cellular defense, mitochondrial energy, immune regulation, and liver detoxification, and how it helps protect cells from daily stress.
- Dave discusses a 2011 University of Texas study showing that oral and liposomal glutathione are completely broken down into raw amino acids before absorption, meaning none of it reaches the bloodstream as glutathione.
- Dave Asprey uses Aura Wellness glutathione topical spray on his abdomen, and it increases his cellular glutathione levels more than an IV. He has used glutathione for 25 years and believes it helps manage senescent cells and improve muscle quality.
Dr. Eric Berg · Glutathione · neutral
- Avocados contain glutathione.
- Notes that nutritional yeast is naturally rich in glutathione, which is one of the most powerful antioxidants in the body, helping to detoxify heavy metals and protect against free radical damage and oxidation.
- Explains that glycine is needed to make glutathione, the antioxidant in the liver that helps break down toxins, and a deficiency in glycine can affect the body's capacity to detoxify.
- Describes glutathione as one of the most powerful compounds in the liver, acting as protection and a bodyguard, and states that having enough of it is key to neutralizing poisons.
- States that glutathione regulates melanin and reduces oxidation, and without enough, melanin spots can occur. He advises increasing glutathione levels to see improvement in hyperpigmentation.
- Explains that glutathione is the master system that controls oxidative stress and regulates melanin, and a lack of it leads to uneven melanin production and aging spots.
- Explains that glutathione is the master detoxification enzyme of the entire body, protecting mitochondria, keeping hydrogen peroxide in check, protecting cell membranes, and supporting other antioxidants.
- Explains that selenium helps build up glutathione, the master antioxidant of the liver and entire body, and is a precursor for its production.
- Explains that a med depletes glutathione, which is the main antioxidant for the liver, and its depletion can destroy the liver.
- Parmigiano Reggiano helps build glutathione, which is a potent antioxidant that supports liver health.
Thomas DeLauer · Glutathione · recommends
- Recommends Row Nutrition's liposomal glutathione for detoxification due to its significantly better absorption compared to standard forms.
- Recommends nano glutathione from Purity Health, noting its liposomal delivery makes it up to 800 times more absorbable.
- Explains that activating the glutathione pathway tells the body to make more endogenously, which is a better approach than oral supplementation due to bioavailability issues.
- States that glutathione, like creatine, is a raw material and not a signaling compound, and he has never seen evidence of withdrawal syndromes with it.
- Recommends glutathione, noting there is good evidence it might help remove some of the toxic load or the stress that comes from it.
- Mentions that supporting glutathione pathways makes melanocytes more resilient to oxidative damage, which is relevant for preventing gray hair.
- Recommends supplementing with liposomal glutathione, especially when under extra stress or when feeling good, as it is one of the only supplements he has seen that can actually increase glutathione levels and help the body deal with stress.
- Warns that if serine is low, the body cannot synthesize glutathione efficiently, meaning that even taking N-acetylcysteine or glutathione supplements will result in the system running at half power.
- Highlights glutathione as one of the body's most important antioxidant and detox molecules, designed to regulate oxidative stress and cytokine production.
- Recommends Rorow Nutrition's liquid liposomal glutathione as a first line of defense against brain inflammation, noting that it has been shown to offer up to 20 times greater absorption compared to non-liposomal powder forms.
Dr. Rhonda Patrick · Glutathione · neutral
- Discusses the truth about glutathione supplements.
- Mentions that Nrf2 up-regulates glutathione, which is the brain and body's primary and most potent antioxidant.
- Sulforaphane also boosts glutathione, your brain’s most powerful antioxidant, far surpassing vitamin C or E.
- Discusses that while alcohol depletes glutathione, and some animal studies suggest boosting glutathione could help mitigate hangover effects, human clinical evidence for liposomal glutathione remains sparse and largely speculative.
- Discusses liposomal glutathione in relation to hangovers.
- Explains that when neurons use lactate as an energy source, it spares glucose, which can then be used to make precursors for glutathione, a powerful antioxidant system in the brain, beneficial for normal brain aging and traumatic brain injury.
- Describes glutathione as the body's most predominant detoxification mechanism and a potent endogenous antioxidant, present at high levels in areas like the macula of the eye.
- Notes that sulforaphane is excreted in the urine as conjugates with glutathione, one of the main antioxidant peptides in the body.
- Dr. Patrick mentions glutathione as a natural antioxidant compound produced by the body.
- Dr. Patrick mentions that heat shock proteins increase endogenous antioxidants in the body, such as glutathione, to prevent protein oxidation.
Siim Land · Glutathione · neutral
- Notes that glycine helps to make glutathione, the master antioxidant.
- Mentions that glutathione is called the master antioxidant, but it is secondary to melatonin and vitamin D.
- States that glutathione is one of the main antioxidant shields against aging and oxidative stress.
- States that glutathione has no effects on skin anti-aging.
- Notes that glutathione is often called the master antioxidant, but its regulation by melatonin is highlighted.
- Does not use injectable glutathione and warns that large quantities of supplements like glutathione taken intravenously can often have harmful effects if taken in large doses without necessity.
- Discusses injectible glutathione, mentioning its role as a powerful antioxidant but also the lack of strong evidence for its widespread use in healthy individuals.
- Mentions that glycine helps to produce glutathione, which is the body's master antioxidant.
- Mentions that sulfur supports the production of glutathione, a powerful antioxidant often used in skincare for whitening the skin and reducing hyperpigmentation, as well as counteracting wrinkles by lowering oxidative stress.
- States that glutathione is good in some situations like infection or disease, but otherwise it's 'okay', and warns that large doses of antioxidants might cause more harm.
Andrew Huberman · Glutathione · neutral
- Dr. Gottfried looks at glutathione in nutritional testing, considering it an important lever.
- Mentions that sulforaphane has been shown in human studies to powerfully increase glutathione in both plasma and the brain through the NRF2 pathway, activating a powerful antioxidant pathway.
- States that glutathione helps Phase 2 liver detoxification, and they use a lot of it intravenously.
- I'm also looking, going back to the antioxidants, at glutathione, because I think that's such an important lever.
- Uses Glutathione, often intravenously, to help with phase 2 liver activity and detoxification.
Bryan Johnson · Glutathione · neutral
- Mentions glutathione as a possible injection or vitamin drip, but does not take a personal stance on it.
- Suggests that glutathione could be really helpful for picking up reactive oxygen species and managing them when exposed to high air quality.
- Bryan Johnson takes L-Glutathione Reduced daily as part of his Longevity Mix, which is a tripeptide antioxidant that helps neutralize free radicals and supports immune health.
RAL Summary
Members OnlyTier 4 for Healthy Aging
Tier 2 needs over 100 reviews with two thirds positive, but no reviews were counted, and none of the studies tested the S-acetyl form or measured biological age, so the evidence is thin. So it is graded Tier 4, lower than the rules alone gave.
Take 2 servings a day to match the dose that worked in the studies.
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 1 of the 4 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Cellular antioxidant defense, Skin, Cardiovascular system
Combine with: S-Acetyl L-Glutathione is an acetylated, more bioavailable form of the body's master antioxidant, helping neutralize reactive oxygen species and protect DNA, proteins, and mitochondria from oxidative damage. To support cellular repair and healthy aging, pair it with NAC or glycine to support endogenous glutathione synthesis, and with vitamin C and vitamin E to help recycle glutathione and broaden antioxidant coverage. Alpha-lipoic acid and selenium (a cofactor for glutathione peroxidase) further support the glutathione system. For DNA repair and mitochondrial support, consider NAD+ precursors such as NMN or nicotinamide riboside, along with CoQ10 or PQQ. Magnesium, riboflavin (B2), and B12/folate support glutathione reductase and methylation pathways. Resveratrol or quercetin can add complementary sirtuin and senescence-related support. Take on an empty stomach for best absorption, and consult a healthcare provider if you are pregnant, on medication, or have a medical condition.
Possible side effects: No major side effects reported for oral glutathione in these studies. A review noted safety concerns with injected glutathione, which is not how this product is taken.
Supplement Facts
S-Acetyl L-Glutathione 100 mg
| S-Acetyl L-Glutathione | 100 mg | † |
Other ingredients: Water, Distilled, Ethanol, Potassium Sorbate, Stevia, Peppermint Oil.
Directions: Suggested use: Shake well before use. Take 12 drops once daily. Hold in mouth for 15 seconds and then swallow. If supplement flavor is too strong, add it into a preferred drink like water or juice and consume.
Barcode (UPC) 685167905100 · Label source: NIH label database · Report a label change
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Graded November 8, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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