Anabolic Warfare Phena-Lean Review
Anabolic Warfare Phena-Lean T2 is presented as a stimulant-free thermogenic body composition support product for men and women, sold as 60 capsules. The listing describes it as a non-stim energy boost for people who find caffeine is not cutting it, with T2 (3,5-Diiodo-L-Thyronine) named as the thermogenic component intended to provide energy for workouts. The page states the formula is built around thermogenic ingredients including CapsiMax, Paradoxine and MitoBurn, which the listing says are designed to help increase energy expenditure and support weight management. A further bullet says each serving contains L-Carnitine and Lean GBB, which the listing says supports nitric oxide production and workout performance. Brown Seaweed Extract is described as supporting well-being and keeping users feeling balanced. Garcinia Cambogia is also named among the special ingredients. Recommended uses shown on the page include pre-workout energy boost, body composition support, weight loss support, and promoting feelings of fullness. The product details table lists the brand as Anabolic Warfare, item form as capsule, unit count as 60 count, product benefit as weight loss support, and a UPC of 812575035949. The page states that all Anabolic Warfare premium supplements are made at the company's cGMP facility using high quality ingredients, and that the brand stands behind its products. The listing carries the standard legal notice that statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. The item is sold by Defyned Brands and ships from Amazon, with a one-time price of $59.99 and a Subscribe and Save option at $53.99 with 10 percent savings. Amazon lists the item as non-returnable due to food safety reasons. The page's disclaimer notes that manufacturers may alter ingredient lists and that buyers should read labels before use.
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Study, Trial or Testing Result Summary
Members Only17 human studies · 1 improved
1 of these 17 human studies gave vitamin b3 by drip, not by mouth.
This product's main ingredient is a 766 mg proprietary blend whose individual doses are hidden. No human studies of the blend were provided, so there is no study evidence that it helps men manage weight. The only other listed ingredient is vitamin B3 at 25 mg, far below the 2000 mg a day used in studies. Even at full doses, vitamin B3 mostly did not help with weight. A review of 15 placebo-controlled trials found no effect on body weight or body mass index [1]. A pooled analysis of 5,144 people found a slight drop in body mass index but no change in body weight [2]. In 40 obese men, 2000 mg a day for 12 weeks did not change body composition or energy use [3]. A 12-week trial in 941 adults found no change in body mass in men or women [4]. In 22 obese men, extended-release niacin worsened insulin sensitivity [5]. One small 28-day trial of 30 overweight adults found about 1.9 kg more weight loss than placebo at 2000 mg a day [6]. None of these findings apply to the trace amount in this product. Animal and cell studies are never counted.
See all 17 studies →Hide the studies
- Across 32 studies of 18,480 children, those with autism ate less niacin and some other vitamins than typically developing children, but this was not a supplement trial and weight and body mass index did not differ.Nutritional Status of Children Diagnosed With Autism Spectrum Disorder: A Systematic Review and Meta-Analysis.
- Pooling 22 treatment arms with 5,144 people, vitamin B3 forms slightly lowered body mass index and raised adiponectin compared with controls, but did not change body weight or leptin, and nicotinic acid lowered body mass index more than nicotinamide.The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a s…
- In a review of 15 placebo-controlled trials of 250-2000 mg a day of nicotinamide mononucleotide for 14 days to 24 weeks, there was no significant effect on body weight or body mass index and no increase in side effects.Safety and Metabolism-Related Outcomes of Oral Nicotinamide Mononucleotide Supplementation in Adults: A Systematic Revie…
- A review of 51 studies of Nigerian adolescents found low dietary niacin intake among other nutrients, but it tested no niacin supplement for weight management.Nutritional status and dietary intake among Nigerian adolescent: a systematic review.
- In 941 adults (40% men) taking 500 or 1000 mg of quercetin combined with vitamin C and niacin daily for 12 weeks, body mass and body composition did not differ from placebo in men or women.Quercetin with vitamin C and niacin does not affect body mass or composition.
- In 40 obese men taking 2000 mg of nicotinamide riboside daily for 12 weeks, body composition, energy expenditure, fat breakdown and insulin sensitivity did not change compared with placebo, and it appeared safe.A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and l…
- In 30 overweight or obese adults aged 45 and over, 1000 mg of nicotinamide mononucleotide twice daily for 28 days raised blood NAD levels and lowered body weight by about 1.9 kg more than placebo, along with lower cholesterol and diastolic blood pressure.Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study.
- In 22 obese men given extended-release niacin or placebo for 8 weeks, niacin reduced insulin sensitivity and changed fat tissue gene signals linked to insulin resistance; weight was not reported.Niacin induces miR-502-3p expression which impairs insulin sensitivity in human adipocytes.
- In 20 overweight African-American women on a modest diet and exercise plan, 600 micrograms a day of niacin-bound chromium for 2 months cut fat more in one group but less in the other group, so results were mixed; this study was in women only.Effects of niacin-bound chromium supplementation on body composition in overweight African-American women.
- In 13 overweight or obese men and women, 1000 mg a day of nicotinamide riboside for 6 weeks slightly raised fat-free mass and sleeping metabolic rate, but did not change insulin sensitivity, fat in the liver or muscle, or inflammation markers.Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in heal…
- In 6 untrained women, a single dose of nicotinic acid before exercise lowered fat burning and raised carbohydrate burning during one hour of cycling; body weight was not studied.Carbohydrate metabolism during exercise in females: effect of reduced fat availability.
- In 11 healthy middle-aged Japanese men, 250 mg per day of nicotinamide mononucleotide for 8 weeks was well tolerated and raised NAD+ in blood cells, with no weight outcome reported.Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide aden…
- In a large Taiwanese survey, obese men were more likely than normal-weight men to meet the recommended intake of vitamin B3 from food, but this is an association and not a test of supplementation.Relationship between overweight and obesity and insufficient micronutrient intake: a nationwide study in Taiwan.
- In 120 people with colon polyps, those with overweight or obesity had lower niacin levels in the polyp tissue than normal-weight people, but this study did not test any supplement.Gut microbiota and metabolome signatures in obese and normal-weight patients with colorectal tumors.
- In 20 pairs of twins who differed in body weight, nicotinamide riboside taken for about 5 months at 250 to 1000 mg per day raised blood NAD+ and muscle mitochondria but did not reduce body fat or improve metabolic health.Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a …
- In 12 children with obesity (8 boys, 4 girls), niacin doses of 250 to 500 mg given every 1 to 2 hours lowered free fatty acids and raised growth hormone, with flushing and tingling as common side effects; body weight was not studied.A pilot study of the effects of niacin administration on free fatty acid and growth hormone concentrations in children w…
- In 10 healthy volunteers, a single intravenous dose of nicotinamide mononucleotide raised blood NAD+ and lowered blood triglycerides, but body weight was not studied.Nicotinamide Mononucleotide Is Safely Metabolized and Significantly Reduces Blood Triglyceride Levels in Healthy Individ…
Review Totals and Summary
Members Only35 reviews · 59% positive
Customers most often praise the energy and focus. Amazon reviewers describe a noticeable lift within the first few days, one of them calling it "a boost of energy", and say it is good for early workouts. Many say it takes the edge off cravings, and some report going about five hours after breakfast without snacking. TikTok users describe a first-day energy surge and fewer cravings. Several say the product is an appetite aid and not a magic fix, and that results still depend on diet and effort. The main complaint is that it is too strong for some people. Reviewers report jitters, a racing or elevated heart rate, and hot flashes. One person said they were "extremely jittery" after a few days and still jittery on day three of trying again. Others warn that anyone sensitive to caffeine should be careful. Taking it in the late afternoon can cause insomnia, so people recommend taking it early. Sellers say the product is meant for users with a high caffeine tolerance, which fits this feedback. Some reviewers feel only the energy and little appetite suppression. One said they stayed hungry even though a previous bottle had worked well for appetite, so the effect seems to vary from person to person. Reviewers outside the user base criticize the capsule's proprietary blend, since doses are not disclosed. One database gave it a thumbs-down for transparency. The powder version, with its fully disclosed label, was welcomed for that reason. Overall, users like it for energy, focus and reduced appetite. They dislike the stimulant side effects, which can be unpleasant for anyone who isn't a seasoned stimulant user. Most of what I found came from Amazon, TikTok and review sites, and I couldn't read many longer reviews from other countries, so this summary may not represent every region.
Biohacker Summary
Members Only3 of 10 recommend it
Our biohacker panel has not discussed this product’s ingredients yet.
RAL Summary
Members OnlyTier 4 for Weight and Metabolism for Men
The ineffective grade rests on vitamin B3, which is only a trace 25 mg here against the 2000 mg used in studies, while the main ingredient, the 766 mg Phena-Lean Blend, has no human studies, so the evidence is thin rather than negative. So it is graded Tier 4, as the studies disagree.
- Emerging: not enough evidence to rank higher yet.
Where the evidence disagrees: 13 of the 17 human studies found no effect.
More Details
Members OnlyBody systems · Combine with · Possible side effects
Body systems: Nervous system, Cardiovascular system, Metabolic system, Digestive system
Combine with: Because Phena-Lean is a thermogenic fat burner, it pairs best with weight management and metabolic support supplements. Consider omega-3 fish oil for cardiovascular support, magnesium glycinate to offset stimulant-related tension and support sleep, and a quality multivitamin to cover nutrient gaps during calorie restriction. Berberine or chromium may support healthy blood sugar and carbohydrate metabolism, and electrolytes help with hydration. Protein or EAAs help preserve lean muscle during a cut. Avoid stacking with other stimulants or high caffeine intake, and stop use 6-8 hours before bed. If cellular and DNA repair is the true goal, choose a separate regimen of NMN or NR, resveratrol, CoQ10, and alpha-lipoic acid. Consult a healthcare provider, especially with heart conditions, high blood pressure, or medications.
Possible side effects: Reviewers report jitters, a racing heart, hot flashes and trouble sleeping when taken late in the day, especially in people sensitive to caffeine. In studies, high-dose extended-release niacin worsened insulin sensitivity, though this product has only a trace amount.
Supplement Facts
Vitamin B3 25 mg · Phena-Lean Blend 766 mg
| Vitamin B3 | 25 mg | |
| Phena-Lean Blend | 766 mg | † |
Other ingredients: Gelatin, Silicon Dioxide, Magnesium Stearate.
Directions: Suggested use Take 1 capsule daily with 8-12 fl. oz. of water.
Barcode (UPC) 812575031866 · Label source: NIH label database · Report a label change
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Graded November 4, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.
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