Barlean's Wild & Whole Alaskan Salmon Oil Review

The page presents Barlean's Fresh & Pure Wild & Whole Alaskan Salmon Oil, sold by NetNutri, and states it is out of stock with only a placeholder count shown. The product is described as wild Alaskan salmon, one of the richest sources of Omega-3 fatty acids EPA and DHA, and as containing Omega-5, 6, 7, 8 and 9. The page says this blend of omegas supports every system in the body, including heart health, cognitive function, visual acuity and a positive mood. Listed features include a full spectrum of Omega-3s, 500 mcg of Super ORAC Antioxidant Astaxanthin, 1,000 IU of Vitamin D3, the nutritional goodness of unrefined salmon oil, a natural triglyceride form described as highly absorbable and easily digestible, sustainable catching, and batch testing by IFOS for purity and safety. The fish is said to be wild caught in the cold waters of Alaska, with minimal processing only to remove possible environmental contaminants including arsenic, lead, cadmium and mercury. Suggested use is 3 softgels daily with a meal. The Barlean family states it aims to provide fine seafood products while remaining mindful of the environment. A nutrition facts image is linked on the page. The page shows no written customer reviews and no star ratings.

Product Focus: CholesterolAlso covers:HeartMetabolism
Tier ⓘ
Tier 3 · Rank 3
Tier 3 · Reviewed. Strong review agreement, with limited or early support from human studies. Rank 3 within Tier 3 for Cholesterol; 18 of 28 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
71 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
93% of 1,500
Biohacker Mentions
8 of 10

Study, Trial or Testing Result Summary

Members Only131 human studies · 55 improved
131 human studies55 improved41 no effect1,287,134 people studied

Vitamin D is present at a full dose, but its results for cholesterol are mixed. In women with polycystic ovary syndrome, it lowered total cholesterol, bad cholesterol and triglycerides [1]. In people with diabetes or prediabetes, it lowered bad cholesterol and raised good cholesterol [2][3]. In pregnant women low in vitamin D, it slightly raised good cholesterol [4]. However, the largest trial, in 2157 older adults over three years, found no change in cholesterol [5]. A review in children with overweight found no benefit and lower good cholesterol [6]. The omega-3 amount is not stated on the label, so it is unclear whether it reaches the doses studied. Omega-3 reliably lowers triglycerides, a blood fat, by about 15 percent, with more benefit at higher doses and little effect on other blood fats [7][8]. Benefits were clearest above 2 grams a day [9]. Fish oil slightly raised good cholesterol, but it also raised bad cholesterol [10][11]. In older adults, 1 gram a day lowered triglycerides but raised bad and total cholesterol [5]. Animal and cell studies are never counted.

See all 131 studies →Hide the studies

Review Totals and Summary

Members Only1,500 reviews · 93% positive
1,500 reviews · Google Shopping 1,500
93% positive0% neutral7% negative

The feedback I could retrieve was limited. It was mostly Amazon reviews, and the sample was small: the 90-count listing showed only about a dozen ratings. The themes below come from that sample, so treat them as indicative rather than comprehensive. Reviewers' most common praise is for purity and quality. One buyer explained that they chose it after comparing independent International Fish Oil Standards data on label accuracy, oxidation and contaminants. They said it offered the best combination of quality and price. Others call it "very pure and clean." Several say it is their favorite fish oil or one of the best. Shoppers like that it is 100% salmon oil, whereas they say other brands blend in other fish oils. The organic and Alaskan labeling is also a reason people pick it, including one buyer who bought it on a sister's recommendation. Brand trust in Barlean's is a recurring reason for buying. The main criticism is unmet expectations of noticeable benefits. One 3-star reviewer bought it after reading that it would improve mood and hair growth. They saw no changes. This is common with fish oil, because effects are gradual and subtle, and many people notice nothing perceptible. Some shoppers also see the price as a trade-off, although the quality-for-price comparison was favorable in the reviews I saw. I did not find enough review text to draw firm conclusions about taste, burps, softgel size or digestive tolerance. Those are common themes for fish oil in general, so check the full review pages on Amazon and other retailers before buying.

Biohacker Summary

Members Only8 of 10 recommend it
8 of 10 biohackers on our panel recommend it

Vitamin D is the main ingredient here, and the panel is largely favorable: four of the ten say they take it, including 5000 units of D3 in the morning for general health and longevity, and D3 in fall and winter when sun is scarce, while several others recommend it for muscle, immune, brain and sperm health. Many want blood levels tested, with targets between 40 and 100 depending on who is speaking, and one panelist says most people are probably deficient but supplementing only makes sense if you are. Because vitamin D is fat soluble, one panelist says to take it with dietary fat rather than alone in the morning with other supplements. Doses vary widely, from 5000 units to 10,000 units daily in winter, and one panelist warns the standard daily recommendation is far too low. Omega-3 is a smaller ingredient in this product, and most of the panel speaks well of it, though one panelist says the research on heart disease outcomes is not strong.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Vitamin D · warns
    • 2 Nov 2026 · warns · Facebook ↗
      Dr. Berg warns that the recommended daily intake for vitamin D is based on a massive error and that the actual necessary amount is closer to 8,895 IU, with millions remaining deficient.
    • 31 Oct 2026 · recommends · YouTube ↗
      Recommends getting vitamin D levels tested to ensure they are between 50 and 70, as vitamin D is intimately involved in regulating prostate size.
    • 31 Oct 2026 · Omega-3 Fatty Acids · recommends · Facebook ↗
      Recommends wild-caught salmon as a healthy food to eat every day, noting it contains about 2000 mg of omega-3s in just 3 ounces.
    • 31 Oct 2026 · Omega-3 Fatty Acids · recommends · Podcast ↗
      Recommends wild salmon as it is rich in omega-3 fatty acids, which help reduce inflammation and support brain health and cognitive function, especially important as one ages.
    • 30 Oct 2026 · recommends · YouTube ↗
      Recommends taking at least 10,000 IUs of vitamin D3 every single day in the winter, stating it is the most important vitamin to lower cancer risk.
    • 30 Oct 2026 · recommends · YouTube ↗
      Recommends vitamin D to support the immune system, aiming for blood levels between 80 to 100 ng per ml.
    • 30 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends DHA, an omega-3 fatty acid, as a natural remedy that, along with sweet wormwood, can trigger iron into an explosion to hit cancer.
    • 25 Oct 2026 · recommends · YouTube ↗
      Recommends taking no less than 10,000 IU's of vitamin D3 for osteoporosis, alongside magnesium and K2.
    • 25 Oct 2026 · recommends · X ↗
      Recommends increasing vitamin D to restore balance and support healthy blood pressure.
    • 24 Oct 2026 · neutral · YouTube ↗
      States that a lack of vitamin D can potentially cause achy bones or crashing mood.
    • 24 Oct 2026 · Omega-3 Fatty Acids · neutral · Facebook ↗
      Dr. Eric Berg mentions that sardines are packed with omega-3 fatty acids, which support brain health and metabolism.
    • 23 Oct 2026 · recommends · YouTube ↗
      States that vitamin D is intimately involved in the immune system and recommends taking at least 10,000 IUs each day.
    • 21 Oct 2026 · recommends · YouTube ↗
      States that taking high doses of vitamin D3 for 14 days can improve mood, sleep, low back pain, skin issues, and blood pressure, as well as act as a natural anti-inflammatory and reduce susceptibility to sickness.
    • 19 Oct 2026 · Omega-3 Fatty Acids · neutral · YouTube ↗
      Mentions that wild salmon, specifically half a fillet, has 970 mg of potassium, zero carbohydrates, a good amount of magnesium, and is loaded with omega-3 fatty acids.
  • Dave Asprey · Vitamin D · uses
    • 1 Nov 2026 · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs.
    • 25 Oct 2026 · recommends · Podcast ↗
      Suggests that vitamin D supports brain health, muscle function, and focus.
    • 25 Oct 2026 · Omega-3 Fatty Acids · recommends · Podcast ↗
      Suggests that omega-3s may help slow aging and support cellular repair.
    • 9 Oct 2026 · recommends · Podcast ↗
      Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
    • 7 Oct 2026 · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 5 Sep 2026 · recommends · YouTube ↗
      Recommends vitamin D, noting it's actually a hormone and that most people are deficient, even those who take it, because they don't take enough.
    • 5 Sep 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends omega-3s, noting that 1 gram a day slowed epigenetic aging by up to 4 months in a randomized trial of people over 70.
    • 3 Sep 2026 · recommends · YouTube ↗
      States that most people on the spectrum are low in vitamin D and need more of it, mentioning his own product, Vitam DAKNE, which contains real vitamin A.
    • 3 Sep 2026 · Omega-6 Fatty Acids · warns · YouTube ↗
      Warns against omega-6 oils, stating he hasn't intentionally had any in 20 years and attributes a significant positive difference in his health to avoiding them.
    • 29 Aug 2026 · recommends · YouTube ↗
      Dave Asprey recommends Vitamin D3 with K2, explaining D3 is a hormone made from sunlight and K2 directs calcium into bones, not arteries, highlighting its low cost, widespread deficiency, and the ability to test its effectiveness.
    • 29 Aug 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Dave Asprey recommends Omega-3, citing a randomized trial showing 1g a day slowed epigenetic aging in older adults, but warns that most people underdose due to low EPA and DHA content in standard capsules.
    • 18 Aug 2026 · recommends · YouTube ↗
      Recommends Vitamin D as one of the most important supplements for overall health.
    • 12 Aug 2026 · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs because D3, A, K2, and E work together.
    • 7 Aug 2026 · Omega-3 Fatty Acids · neutral · Podcast ↗
      A review of 41 human studies testing interventions against newer-generation epigenetic clocks found favorable changes for exercise, caloric restriction, omega-3s, plant-rich diets, multivitamins, a med, pitavastatin, and ketamine.
  • Siim Land · Vitamin D · recommends
    • 31 Oct 2026 · recommends · YouTube ↗
      Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
    • 31 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends taking omega-3s, including EPA and DHA, with a fat-containing meal to increase absorption.
    • 29 Oct 2026 · recommends · Instagram ↗
      Recommends taking Vitamin D with fat for better absorption.
    • 24 Oct 2026 · neutral · Instagram ↗
      States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
    • 21 Oct 2026 · Omega-3 Fatty Acids · uses · YouTube ↗
      Increased his omega-3 intake to achieve a higher omega-3 index, which is associated with greater insulin sensitivity and better metabolic health markers.
    • 13 Oct 2026 · Omega-3 Fatty Acids · uses · Instagram ↗
      Increased his omega-3 index to 9.5% and notes that omega-3s have strong evidence for reducing elevated triglycerides.
    • 9 Oct 2026 · Omega-3 Fatty Acids · neutral · Instagram ↗
      Mentions that EPA and DHA Omega-3s support heart and brain function and can lower triglycerides, with a higher omega-3 index associated with lower heart disease, Alzheimer's and mortality risk.
    • 7 Oct 2026 · Omega-3 Fatty Acids · recommends · Instagram ↗
      Recommends Omega-3s for triglycerides and cardiovascular health, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 7 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends choosing an omega-3 supplement from a brand that uses independent third-party testing and publishes a recent certificate of analysis, verifying EPA and DHA amounts, and testing for heavy metals, contaminants, and oxidation markers.
    • 6 Oct 2026 · Omega-3 Fatty Acids · neutral · X ↗
      Lists Omega-3s as one of 15 supplements backed by human studies.
    • 2 Oct 2026 · Omega-3 Fatty Acids · neutral · YouTube ↗
      Explains that omega-3s can alter mitochondrial membranes and have broader cardiometabolic effects, making mitochondria more responsive to cellular signaling and oxidative stress from exercise, but they don't increase maximal mitochondrial respiration.
    • 28 Sep 2026 · Omega-3 Fatty Acids · recommends · Instagram ↗
      Notes that 75% of people aren't meeting the daily recommendation for omega-3s and that Japanese people eat 2-3x more omega-3s per day than Americans or Europeans, which reflects in their higher omega-3 index.
    • 6 Sep 2026 · recommends · Instagram ↗
      Thinks vitamin D has some of the strongest evidence and is worth considering.
    • 6 Sep 2026 · neutral · X ↗
      Notes that Vitamin K2 pairs well with vitamin D by regulating calcium and bone mineralization.
  • Ben Greenfield · Vitamin D · recommends
    • 29 Oct 2026 · recommends · YouTube ↗
      Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
    • 15 Oct 2026 · recommends · Podcast ↗
      Mentions vitamin D as part of a bare-minimum protocol.
    • 15 Oct 2026 · recommends · YouTube ↗
      Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
    • 21 Sep 2026 · Omega-3 Fatty Acids · neutral · Facebook ↗
      Notes that omega-3s have solid research behind them for fertility.
    • 19 Sep 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends omega-3 fatty acids, specifically EPA and DHA, at 1 to 3 grams per day for better sperm morphology and motility, noting that sperm membranes are rich in polyunsaturated fatty acids.
    • 8 Sep 2026 · Omega-3 Fatty Acids · recommends · X ↗
      Recommends getting Omega-3 from oily fish such as sardines, anchovies, mackerel, herring, and salmon with skin.
    • 22 Aug 2026 · Omega-3 Fatty Acids · neutral · Facebook ↗
      Discusses why fatty fish or fish oil may matter more than plant-based omega-3s if seed oils are in one's diet.
    • 20 Aug 2026 · uses · YouTube ↗
      Has been taking Vitamin D3 K2 for over a decade.
    • 8 Aug 2026 · neutral · Instagram ↗
      Notes that sunlight influences more than just vitamin D production.
    • 8 Aug 2026 · recommends · YouTube ↗
      Recommends keeping vitamin D levels high, suggesting that a supplement is probably not a bad idea, especially given that many people are deficient due to spending most of their time indoors.
    • 25 Jul 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Says that omega-3 fatty acids are a great way to feed the system and help with stress.
    • 18 Jul 2026 · recommends · YouTube ↗
      Recommends getting enough vitamin D for blood pressure management.
    • 9 Jul 2026 · recommends · YouTube ↗
      Recommends optimizing vitamin D levels to a serum score of around 50 to 80 nanograms per milliliter, as deficiency is linked to tinnitus volume and can assist with it.
    • 9 Jul 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends testing for and replenishing omega-3 fatty acids if levels are low, as they can affect the ability to maintain or preserve muscle, especially for those on GLP-1s.
  • Dr. Mark Hyman · Vitamin D · recommends
    • 26 Oct 2026 · recommends · Facebook ↗
      Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
    • 21 Oct 2026 · neutral · YouTube ↗
      Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 21 Oct 2026 · Omega-3 Fatty Acids · neutral · YouTube ↗
      Mentions omega-3 fats as existing biomarkers that play a role in mental health, which Function Health includes in their measurements.
    • 19 Oct 2026 · neutral · YouTube ↗
      Notes that vitamin D plays a role in immune function.
    • 9 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Mentions that omega-3s are anti-inflammatory and helpful.
    • 8 Oct 2026 · recommends · Instagram ↗
      Recommends checking vitamin D levels and states that if they had to pick one single intervention for immune health, vitamin D would be it.
    • 7 Oct 2026 · neutral · Podcast ↗
      Dr. Hyman discusses vitamin D in relation to sun exposure patterns.
    • 7 Oct 2026 · recommends · YouTube ↗
      States that vitamin D supplementation can help with oxidative stress.
    • 7 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Tries to supplement with omega-3s for psoriasis and considers them the one clearly clinically effective skin nutrient for skin, hair, and nails.
    • 5 Oct 2026 · neutral · Podcast ↗
      Mentions vitamin D as a key nutrient for supporting immune function.
    • 5 Oct 2026 · recommends · YouTube ↗
      States that vitamin D is probably the single most important intervention for immune health, recommending levels of 45 to 70 and emphasizing testing to determine the right dose.
    • 30 Sep 2026 · neutral · YouTube ↗
      Notes that rickets, which causes terrible bone deformities, is caused by vitamin D deficiency.
    • 30 Sep 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Emphasizes the importance of focusing on omega-3s, noting that a national crisis of omega-3 deficiency exists and that low omega-3 levels are a significant problem, more so than omega-6s.
    • 30 Sep 2026 · Omega-6 Fatty Acids · neutral · YouTube ↗
      Clarifies that the concept of omega-6 polyunsaturated fatty acids being pro-inflammatory, derived from molecular theories and animal research, does not hold true in humans.
  • Thomas DeLauer · Vitamin D · uses
    • 23 Oct 2026 · uses · YouTube ↗
      Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
    • 27 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends fish oil supplements as an omega-3 source for gut health, as they help reduce inflammatory signaling while tissue repairs.
    • 23 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends high-dose omega-3s, specifically 2 to four grams of combined EPA and DHA daily, to lower hepatic fat output and improve chylomicron clearance, which helps with non-fasting triglycerides.
    • 20 Oct 2026 · recommends · YouTube ↗
      Recommends taking a massive amount of vitamin D simultaneously with an early morning massive breakfast to help reset circadian rhythms and address hyperphagia.
    • 19 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends omega-3s, specifically 4 grams a day, to boost the muscle building response by making muscle cell membranes work better for the mTor switch to fire, and specifically mentions Pury for their clean, third-party tested omega-3s.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends Vitamin D, stating that it has receptors throughout the brain and deficiency can quickly impact brain and mood.
    • 7 Oct 2026 · Omega-7 Fatty Acids · recommends · YouTube ↗
      Recommends palmitoleic acid, an omega-7 fat, as another food that can lower blood sugar, potentially even better than apple cider vinegar.
    • 6 Oct 2026 · uses · YouTube ↗
      Takes supplemental vitamin D because he is skin sensitive and from northern latitudes, limiting his UV exposure.
    • 5 Oct 2026 · recommends · YouTube ↗
      Recommends taking vitamin D on non-liver days to ensure both nutrients get proper receptor access.
    • 4 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends consuming more omega-3s to help balance the mitochondrial membrane, as it will absorb more omega-3s instead of omega-6s.
    • 1 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends consuming more omega-3s to drive down inflammation.
    • 29 Sep 2026 · uses · YouTube ↗
      Takes Purity's liquid vitamin D3 with K2 because she is constantly inside during the day; D3 is for overall wellness and K2 helps the body absorb calcium properly.
    • 11 Sep 2026 · recommends · YouTube ↗
      Recommends getting vitamin D, suggesting it can be obtained while walking.
    • 8 Sep 2026 · Omega-3 Fatty Acids · stopped · YouTube ↗
      Recommends omega-3s, stating that a meta-analysis found 1,000 mg significantly reduced liver fat by shutting down inflammatory signals that promote fat storage, and advises looking for a triglycerol form for better absorption and to avoid oxidation.
  • Bryan Johnson · Vitamin D · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Aug 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 3 Jul 2026 · neutral · X ↗
      Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
    • 4 May 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for longevity.
    • 2 May 2026 · uses · X ↗
      He takes 5000 IU of Vitamin D3 in the morning for general health.
    • 21 Apr 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Apr 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for longevity.
    • 14 Apr 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning.
    • 8 Apr 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning.
    • 7 Apr 2026 · uses · X ↗
      He takes 5000 IU of Vitamin D3 in the morning for general health.
  • Dr. Rhonda Patrick · Vitamin D · neutral
    • 5 Oct 2026 · neutral · Facebook ↗
      Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
    • 22 Oct 2026 · Omega-3 Fatty Acids · neutral · Instagram ↗
      Mentions that EPA is an omega-3 examined in mortality analysis and found primarily in seafood.
    • 30 Sep 2026 · recommends · YouTube ↗
      Mentions that vitamin D also plays a role in maintaining muscle mass.
    • 28 Sep 2026 · recommends · YouTube ↗
      Recommends ensuring adequate vitamin D intake for men's sperm health.
    • 28 Sep 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      States that Omega-3 fatty acids are very important for sperm health.
    • 24 Sep 2026 · neutral · Facebook ↗
      Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
    • 24 Sep 2026 · Omega-3 Fatty Acids · neutral · Facebook ↗
      Omega-3s may help slow biological aging, with added benefits when combined with vitamin D and strength training. In a 3-year randomized trial of healthy, mostly active older adults, omega-3 alone slowed several DNA-based aging clocks.
    • 21 Sep 2026 · Omega-3 Fatty Acids · recommends · Instagram ↗
      Recommends regular intake of omega-3 rich seafood and supplementation with omega-3 fatty acids if it's appropriate for one's lifestyle, as they are beneficial for the heart by resolving inflammation and preserving membrane fluidity.
    • 16 Sep 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Notes that a 100 mg per day increase in omega-3 fatty acids was associated with lowering the risk of Alzheimer's disease and cognitive decline by 10%, and that it takes about two grams a day to get to a high omega-3 index if one has a low index.
    • 15 Sep 2026 · Omega-3 Fatty Acids · recommends · Facebook ↗
      Practical habits to help keep chronic inflammation in check include getting enough omega-3s.
    • 11 Sep 2026 · Omega-3 Fatty Acids · neutral · Facebook ↗
      States that Omega-3s, specifically EPA and DHA, may be the most potent naturally occurring dietary compounds for reducing inflammation, and that about 2 g/day of combined EPA and DHA can raise a low omega-3 index.
    • 1 Sep 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends fatty fish as a source of healthy fats for muscle gain.
    • 30 Aug 2026 · Omega-3 Fatty Acids · neutral · YouTube ↗
      Mentions that an omega-3 supplement might not be working, and one would not know without taking the Omega-3 index test.
    • 25 Aug 2026 · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
  • Andrew Huberman · Vitamin D · neutral
    • 21 Sep 2026 · neutral · YouTube ↗
      Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
    • 29 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      AG1 is giving away a free bottle of omega-3 coenzyme Q10 with your first subscription.
    • 26 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Mentions that AG1 is giving away a free bottle of Omega-3 co-enzyme Q10 with the first subscription to AG1 Pro.
    • 22 Oct 2026 · Omega-3 Fatty Acids · neutral · Podcast ↗
      Discusses Omega-3 Fatty Acids and EPA.
    • 19 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Mentions that AG1 is offering a free bottle of Omega-3 co-enzyme Q10 with a first subscription to AG1 Pro.
    • 12 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends a free bottle of Omega-3 co-enzyme Q10 with the first AG1 Pro subscription.
    • 12 Oct 2026 · Omega-3 Fatty Acids · neutral · Podcast ↗
      Mentions Omega-3s in the context of the microbiome and processed foods.
    • 5 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      Recommends Omega-3 co-enzyme Q10, which is offered as a free bottle with the first AG1 Pro subscription.
    • 1 Oct 2026 · Omega-3 Fatty Acids · recommends · YouTube ↗
      States that getting 1 to 3 grams of EPA essential fatty acid per day can improve mood and cognitive function, supporting focus and concentration.
    • 1 Oct 2026 · Omega-3 Fatty Acids · neutral · Podcast ↗
      Discusses Omega-3 Fatty Acids.
    • 21 Sep 2026 · Omega-3 Fatty Acids · neutral · Podcast ↗
      Discusses omega-3s, artificial sweeteners, fructose, and fats.
    • 7 Aug 2026 · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for longevity.
    • 20 Jul 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 20 Jul 2026 · recommends · YouTube ↗
      States that Vitamin D is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
  • Peter Attia · Vitamin D · uses
    • 4 Jan 2026 · uses · YouTube ↗
      Lists vitamin D as one of her staple supplements.
    • 14 Sep 2026 · Omega-3 Fatty Acids · neutral · Podcast ↗
      Peter and Michael explore the benefits of omega-3 fatty acids for cardiovascular trials and the challenge of delivering DHA to the brain.
    • 18 Jan 2026 · Omega-3 Fatty Acids · neutral · YouTube ↗
      Mentions that some trials showing a benefit to PUFA were confounded by the inclusion of omega-3s, and argues that the literature on omega-3s is not super strong for decreasing hard cardiovascular disease endpoints.
    • 4 Jan 2026 · Omega-3 Fatty Acids · uses · YouTube ↗
      Took big doses of omega-3 postpartum to help maintain when she wasn't sitting down to eat full meals.
    • 10 Dec 2025 · Omega-3 Fatty Acids · uses · YouTube ↗
      Mentions consuming fatty fish, specifically sardines, as part of their diet, noting their high fat and protein content.
    • 16 Nov 2025 · neutral · YouTube ↗
      Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 6 Aug 2025 · neutral · YouTube ↗
      States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
    • 3 Aug 2025 · neutral · YouTube ↗
      Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
    • 20 Jul 2025 · neutral · YouTube ↗
      In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
    • 10 Jul 2025 · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends Vitamin D3 as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 800 to 1,000 IU, which can be obtained through sunlight or supplementation.
    • 6 Jul 2025 · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might overcome the negative effects of phenytoin on bone health by counteracting increased catabolism of vitamin D and subsequent decreased calcium absorption.
    • 8 Jun 2025 · recommends · YouTube ↗
      Recommends vitamin D for people who tend to be vitamin D deficient, such as those living in Portland, Oregon.
    • 17 Mar 2025 · neutral · Instagram ↗
      Discusses evaluating vitamin D, understanding deficiency, and optimal levels.

RAL Summary

Members OnlyTier 3 for Cholesterol

Tier 3 rests on 1500 reviews, 93 percent of them positive. The study support is limited: omega-3 lowers triglycerides but not bad cholesterol, and vitamin D gives mixed cholesterol results [7][5].

  • Omega-3 Fatty Acids: amount hidden in a blend

Where the evidence disagrees: 41 of the 131 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Cardiovascular system, Metabolic system

Combine with: For immune support, pair this salmon oil with vitamin D3 (ideally with K2), vitamin C, and zinc, which directly support immune cell function. Selenium, elderberry, beta-glucans, and probiotics add further immune and gut-immune support. If using the oil for its cardiovascular benefits, it also stacks well with CoQ10, magnesium, and vitamin E (as mixed tocopherols) to support heart health and protect the oils from oxidation. Take it with a meal containing fat to improve absorption, and consult a healthcare provider if you use meds.

Possible side effects: Fish oil can raise bad cholesterol in some people, and one trial found higher cholesterol with high-dose vitamin D. No other major side effects were reported.

Supplement Facts

Vitamin D3 1000 IU · Omega-3 Fatty Acids 0
Supplement Facts
Serving Size 3 Softgel(s)
Servings Per Container 30
Amount Per Serving% Daily Value
Calories25
Total Fat2.5 g
Cholesterol15 mg
Vitamin D31,000 IU
Omega-3 Fatty Acids0†
† Daily Value not established.

Other ingredients: Wild Alaskan Salmon Fish Oil, Softgel.

Directions: Suggested Use: 3 softgels daily with a meal.

Label source: NIH label database · Report a label change

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Graded November 4, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.